Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | NADH oxidase | 0.0073 | 0.0226 | 0.0586 |
Plasmodium falciparum | thioredoxin reductase | 0.0211 | 0.1164 | 0.2856 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0073 | 0.0226 | 0.0515 |
Brugia malayi | AF-10 protein | 0.004 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0536 | 0.337 | 0.7754 |
Mycobacterium tuberculosis | Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase | 0.0356 | 0.2152 | 0.4951 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0536 | 0.337 | 0.7754 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0482 | 0.3005 | 0.6912 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0202 | 0.1102 | 0.2532 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0294 | 0.1725 | 0.3966 |
Brugia malayi | GMP reductase | 0.0282 | 0.1647 | 0.1882 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.019 | 0.1022 | 0.2349 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0073 | 0.0226 | 0.0515 |
Loa Loa (eye worm) | glutaminase | 0.0313 | 0.186 | 0.2125 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0071 | 0.0213 | 0.0244 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0144 | 0.0709 | 0.1626 |
Brugia malayi | jmjC domain containing protein | 0.0149 | 0.0743 | 0.0848 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0062 | 0.015 | 0.0342 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0255 | 0.1459 | 0.1667 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0054 | 0.0093 | 0.0107 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.019 | 0.1022 | 0.2349 |
Schistosoma mansoni | alpha-glucosidase | 0.0301 | 0.1776 | 0.4085 |
Loa Loa (eye worm) | chloride channel 3 | 0.004 | 0.0002 | 0.0002 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0073 | 0.0226 | 0.0515 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0601 | 0.3816 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0071 | 0.0213 | 0.0244 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0123 | 0.0566 | 0.1299 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0144 | 0.0709 | 0.1627 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0073 | 0.0226 | 0.055 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0213 | 0.0487 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0536 | 0.337 | 0.7754 |
Echinococcus granulosus | geminin | 0.0165 | 0.085 | 0.1952 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0073 | 0.0226 | 0.0515 |
Loa Loa (eye worm) | loechrig isoform VII | 0.004 | 0.0002 | 0.0002 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.019 | 0.1022 | 0.2349 |
Trichomonas vaginalis | glutaminase, putative | 0.0313 | 0.186 | 0.186 |
Mycobacterium leprae | Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) | 0.0679 | 0.4346 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0601 | 0.3816 | 0.3816 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.035 | 0.2108 | 0.2408 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0078 | 0.0256 | 0.0585 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0078 | 0.0256 | 0.0292 |
Brugia malayi | glutathione reductase | 0.0211 | 0.1164 | 0.133 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.0165 | 0.0375 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.0165 | 0.0188 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.0518 | 0.0592 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.0256 | 0.0585 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0144 | 0.0709 | 0.0809 |
Plasmodium falciparum | phd finger protein, putative | 0.0123 | 0.0566 | 0.1387 |
Brugia malayi | Voltage gated chloride channel family protein | 0.004 | 0.0002 | 0.0002 |
Brugia malayi | Bromodomain containing protein | 0.0123 | 0.0566 | 0.0647 |
Brugia malayi | Pre-SET motif family protein | 0.1327 | 0.8753 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.151 | 1 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0211 | 0.1164 | 0.2856 |
Loa Loa (eye worm) | GMP reductase | 0.0282 | 0.1647 | 0.1882 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0213 | 0.0487 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0073 | 0.0226 | 0.0515 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0073 | 0.0226 | 0.0515 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0054 | 0.0093 | 0.0107 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0073 | 0.0226 | 0.0515 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0601 | 0.3816 | 0.3816 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.0165 | 0.0375 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.035 | 0.2108 | 0.4848 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0213 | 0.1179 | 0.271 |
Wolbachia endosymbiont of Brugia malayi | IMP dehydrogenase | 0.0679 | 0.4346 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0073 | 0.0226 | 0.0515 |
Echinococcus multilocularis | peregrin | 0.0123 | 0.0566 | 0.1299 |
Giardia lamblia | PHD finger protein 15 | 0.0123 | 0.0566 | 0.1479 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0144 | 0.0709 | 0.1627 |
Onchocerca volvulus | Putative GMP reductase | 0.0282 | 0.1647 | 0.1647 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0213 | 0.0213 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0123 | 0.0566 | 0.1299 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.019 | 0.1022 | 0.2349 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0058 | 0.0122 | 0.0139 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0073 | 0.0226 | 0.0515 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0183 | 0.0975 | 0.2239 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0062 | 0.015 | 0.0342 |
Schistosoma mansoni | alpha-glucosidase | 0.0301 | 0.1776 | 0.4085 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0064 | 0.0165 | 0.0375 |
Echinococcus granulosus | inosine 5' monophosphate dehydrogenase 2 | 0.0679 | 0.4346 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0211 | 0.1164 | 0.133 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0213 | 0.0487 |
Trypanosoma cruzi | GMP reductase | 0.0679 | 0.4346 | 1 |
Leishmania major | trypanothione reductase | 0.0211 | 0.1164 | 0.2676 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0078 | 0.0256 | 0.0585 |
Brugia malayi | PHD-finger family protein | 0.004 | 0.0002 | 0.0002 |
Brugia malayi | jmjC domain containing protein | 0.0404 | 0.2474 | 0.2826 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0073 | 0.0226 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.019 | 0.1022 | 0.2349 |
Plasmodium falciparum | thioredoxin reductase | 0.0073 | 0.0226 | 0.055 |
Mycobacterium ulcerans | inosine 5-monophosphate dehydrogenase | 0.0322 | 0.1921 | 0.4418 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.0256 | 0.0585 |
Trypanosoma brucei | trypanothione reductase | 0.0211 | 0.1164 | 0.2676 |
Brugia malayi | ancient conserved domain protein 2 | 0.004 | 0.0002 | 0.0002 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0062 | 0.015 | 0.0342 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0482 | 0.3005 | 0.6912 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0211 | 0.1164 | 0.133 |
Trypanosoma brucei | inosine-5'-monophosphate dehydrogenase | 0.0679 | 0.4346 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0601 | 0.3816 | 0.3816 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0601 | 0.3816 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0073 | 0.0226 | 0.0226 |
Schistosoma mansoni | glutaminase | 0.0313 | 0.186 | 0.4277 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0144 | 0.0709 | 0.0809 |
Trypanosoma cruzi | inosine-5'-monophosphate dehydrogenase, putative | 0.0679 | 0.4346 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0078 | 0.0256 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0002 | 0.0002 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0078 | 0.0256 | 0.0256 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.085 | 0.1952 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0047 | 0.0049 | 0.0057 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0073 | 0.0226 | 0.0515 |
Trypanosoma brucei | glucosidase, putative | 0.0078 | 0.0256 | 0.0585 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0073 | 0.0226 | 0.0515 |
Trypanosoma cruzi | inosine-5'-monophosphate dehydrogenase, putative | 0.0679 | 0.4346 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.0165 | 0.0375 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.035 | 0.2108 | 0.2408 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0062 | 0.015 | 0.0172 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0078 | 0.0256 | 0.0292 |
Leishmania major | guanosine monophosphate reductase | 0.0679 | 0.4346 | 1 |
Echinococcus granulosus | peregrin | 0.0123 | 0.0566 | 0.1299 |
Plasmodium vivax | SET domain protein, putative | 0.019 | 0.1022 | 0.2508 |
Trypanosoma brucei | GMP reductase | 0.0679 | 0.4346 | 1 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0073 | 0.0226 | 0.0515 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.0165 | 0.0375 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.0518 | 0.0592 |
Mycobacterium leprae | PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) | 0.0322 | 0.1921 | 0.4418 |
Onchocerca volvulus | Alhambra homolog | 0.0123 | 0.0566 | 0.0566 |
Echinococcus multilocularis | inosine 5' monophosphate dehydrogenase 2 | 0.0679 | 0.4346 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0123 | 0.0566 | 0.0647 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | glutaminase 2 | 0.0313 | 0.186 | 0.2125 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0149 | 0.0743 | 0.1705 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0062 | 0.015 | 0.0342 |
Brugia malayi | inosine-5'-monophosphate dehydrogenase | 0.0282 | 0.1647 | 0.1882 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.019 | 0.1022 | 0.2349 |
Trypanosoma cruzi | GMP reductase | 0.0679 | 0.4346 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.035 | 0.2108 | 0.4848 |
Onchocerca volvulus | 0.0202 | 0.1102 | 0.1102 | |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0213 | 0.0213 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.0518 | 0.0592 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0601 | 0.3816 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0078 | 0.0256 | 0.0256 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0404 | 0.2474 | 0.569 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0021 | 0.0021 |
Brugia malayi | inosine-5'-monophosphate dehydrogenase | 0.0282 | 0.1647 | 0.1882 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0213 | 0.1179 | 0.271 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.0165 | 0.0375 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0073 | 0.0226 | 0.0515 |
Schistosoma mansoni | inosine-5-monophosphate dehydrogenase | 0.0679 | 0.4346 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0073 | 0.0226 | 0.055 |
Mycobacterium ulcerans | glutaminase | 0.0313 | 0.186 | 0.4277 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0062 | 0.015 | 0.0342 |
Brugia malayi | CLC chloride channel protein | 0.004 | 0.0002 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.0566 | 0.1299 |
Onchocerca volvulus | 0.0202 | 0.1104 | 0.1104 | |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0078 | 0.0256 | 0.0249 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0144 | 0.0709 | 0.1626 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0073 | 0.0226 | 0.055 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0062 | 0.015 | 0.0342 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0047 | 0.0049 | 0.011 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0601 | 0.3816 | 0.3816 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0601 | 0.3816 | 0.3816 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0144 | 0.0709 | 0.1626 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0073 | 0.0226 | 0.0515 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.035 | 0.2108 | 0.4848 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0073 | 0.0226 | 0.0515 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0062 | 0.015 | 0.0342 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0294 | 0.1725 | 0.3966 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0601 | 0.3816 | 0.3816 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0002 | 0.0002 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0211 | 0.1164 | 0.2676 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0073 | 0.0226 | 0.0515 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0073 | 0.0226 | 0.0515 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0078 | 0.0256 | 0.0585 |
Onchocerca volvulus | 0.004 | 0.0002 | 0.0002 | |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0073 | 0.0226 | 0.0515 |
Mycobacterium tuberculosis | Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase | 0.0679 | 0.4346 | 1 |
Mycobacterium leprae | Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena | 0.0356 | 0.2152 | 0.4951 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0213 | 0.0487 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0149 | 0.0743 | 0.0848 |
Brugia malayi | Pre-SET motif family protein | 0.019 | 0.1022 | 0.1168 |
Mycobacterium ulcerans | inosine 5'-monophosphate dehydrogenase | 0.0679 | 0.4346 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0149 | 0.0743 | 0.1705 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0073 | 0.0226 | 0.055 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0536 | 0.337 | 0.7754 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0601 | 0.3816 | 0.3816 |
Brugia malayi | Thioredoxin reductase | 0.0211 | 0.1164 | 0.133 |
Mycobacterium tuberculosis | Probable reductase | 0.0482 | 0.3005 | 0.6912 |
Loa Loa (eye worm) | IMP dehydrogenase 1 | 0.0679 | 0.4346 | 0.4965 |
Brugia malayi | loechrig isoform VII | 0.004 | 0.0002 | 0.0002 |
Brugia malayi | PHD-finger family protein | 0.0123 | 0.0566 | 0.0647 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.1327 | 0.8753 | 1 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0073 | 0.0226 | 0.0586 |
Plasmodium falciparum | inosine-5'-monophosphate dehydrogenase | 0.0639 | 0.4072 | 1 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0123 | 0.0566 | 0.1299 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0073 | 0.0226 | 0.055 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.0165 | 0.0375 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0144 | 0.0709 | 0.1626 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0213 | 0.0487 |
Brugia malayi | inosine-5'-monophosphate dehydrogenase family protein | 0.0679 | 0.4346 | 0.4965 |
Schistosoma mansoni | alpha glucosidase | 0.0078 | 0.0256 | 0.0585 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0601 | 0.3816 | 0.3816 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0078 | 0.0256 | 0.0256 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0078 | 0.0256 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0211 | 0.1165 | 0.1331 |
Brugia malayi | ancient conserved domain protein 4 | 0.004 | 0.0002 | 0.0002 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0172 | 0.0895 | 0.2055 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0149 | 0.0743 | 0.1705 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0078 | 0.0256 | 0.0256 |
Plasmodium falciparum | glutathione reductase | 0.0211 | 0.1164 | 0.2856 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0073 | 0.0226 | 0.0515 |
Schistosoma mansoni | jumonji domain containing protein | 0.0321 | 0.1909 | 0.4391 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0073 | 0.0226 | 0.0515 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0482 | 0.3005 | 0.6912 |
Toxoplasma gondii | thioredoxin reductase | 0.0211 | 0.1164 | 0.2676 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0064 | 0.0165 | 0.0188 |
Plasmodium vivax | hypothetical protein, conserved | 0.0123 | 0.0566 | 0.1387 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.085 | 0.1952 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0249 | 0.1422 | 0.327 |
Toxoplasma gondii | IMP dehydrogenas | 0.0679 | 0.4346 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.0566 | 0.0647 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0073 | 0.0226 | 0.0515 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0073 | 0.0226 | 0.0258 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0073 | 0.0226 | 0.0515 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0073 | 0.0226 | 0.0515 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0078 | 0.0256 | 0.0585 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0149 | 0.0743 | 0.1705 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0078 | 0.0256 | 0.0256 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0073 | 0.0226 | 0.0226 |
Brugia malayi | glutaminase DH11.1 | 0.0313 | 0.186 | 0.2125 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0073 | 0.0226 | 0.0515 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0211 | 0.1164 | 0.2856 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0078 | 0.0256 | 0.0256 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0123 | 0.0566 | 0.1299 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0213 | 0.0487 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0078 | 0.0256 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0002 | 0.0002 |
Plasmodium vivax | inosine-5'-monophosphate dehydrogenase, putative | 0.0639 | 0.4072 | 1 |
Echinococcus multilocularis | geminin | 0.0165 | 0.085 | 0.1952 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0404 | 0.2474 | 0.569 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0482 | 0.3005 | 0.6912 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0021 | 0.0021 |
Mycobacterium ulcerans | inosine 5-monophosphate dehydrogenase | 0.0639 | 0.4072 | 0.9369 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0144 | 0.0709 | 0.1627 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0211 | 0.1164 | 0.2676 |
Trypanosoma cruzi | inosine-5'-monophosphate dehydrogenase, putative | 0.0679 | 0.4346 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.019 | 0.1022 | 0.2349 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0078 | 0.0256 | 0.0256 |
Leishmania major | inosine-5-monophosphate dehydrogenase | 0.0679 | 0.4346 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0601 | 0.3816 | 1 |
Loa Loa (eye worm) | chloride channel protein 7 | 0.004 | 0.0002 | 0.0002 |
Brugia malayi | CBS domain containing protein | 0.004 | 0.0002 | 0.0002 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0073 | 0.0226 | 0.0515 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0073 | 0.0226 | 0.0515 |
Brugia malayi | chloride channel protein 7 | 0.004 | 0.0002 | 0.0002 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0073 | 0.0226 | 0.0515 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0482 | 0.3005 | 0.6912 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0482 | 0.3005 | 0.6912 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0123 | 0.0566 | 0.1299 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1022 | 0.1168 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0294 | 0.1725 | 0.3966 |
Echinococcus granulosus | jumonji domain containing protein | 0.0172 | 0.0895 | 0.2055 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0073 | 0.0226 | 0.0515 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.