Detailed information for compound 1154079

Basic information

Technical information
  • TDR Targets ID: 1154079
  • Name: ethyl-tri(phenyl)phosphanium
  • MW: 291.347 | Formula: C20H20P+
  • H donors: 0 H acceptors: 0 LogP: 4.99 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1
  • InChi: 1S/C20H20P/c1-2-21(18-12-6-3-7-13-18,19-14-8-4-9-15-19)20-16-10-5-11-17-20/h3-17H,2H2,1H3/q+1
  • InChiKey: GELSOTNVVKOYAW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • ethyl-tri(phenyl)phosphonium
  • Ethyltriphenylphosphonium iodide, polymer-bound
  • 572934_ALDRICH

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0079 0.0207
Loa Loa (eye worm) hypothetical protein 0.0286 0.3435 1
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.0079 0.0099
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0523 0.1411
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0523 0.048
Echinococcus multilocularis cysteine protease 0.002 0.0206 0.0162
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0013 0.0112 0.3945
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0013 0.0112 0.0983
Plasmodium vivax serine-repeat antigen (SERA) 0.0013 0.0112 0.3945
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.0079 0.0083
Onchocerca volvulus 0.002 0.0206 0.4689
Schistosoma mansoni cpg binding protein 0.0029 0.0312 0.0889
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.0079 0.0034
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0206 1
Trichomonas vaginalis ferritin, putative 0.001 0.0077 0.0674
Onchocerca volvulus 0.002 0.0206 0.4689
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0013 0.0112 0.0983
Brugia malayi Cathepsin L-like precursor 0.002 0.0206 0.0459
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0206 1
Loa Loa (eye worm) cathepsin B 0.0097 0.114 0.3218
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.002 0.0206 0.0578
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0112 0.0983
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0037 0.0328
Brugia malayi cathepsin Z-like cysteine proteinase 0.0013 0.0112 0.0181
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0013 0.0112 0.3945
Onchocerca volvulus Cathepsin L homolog 0.002 0.0206 0.4689
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0112 0.0983
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0112 0.0983
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0067 0.0064
Brugia malayi transcription factor E74 isoform 0.001 0.0079 0.0083
Brugia malayi Cathepsin L-like precursor 0.002 0.0206 0.0459
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0206 0.1807
Echinococcus multilocularis ets variant gene 4 0.001 0.0079 0.0034
Brugia malayi CXXC zinc finger family protein 0.0029 0.0312 0.0773
Brugia malayi Papain family cysteine protease containing protein 0.0013 0.0112 0.0181
Schistosoma mansoni ferritin light chain 0.001 0.0077 0.0201
Toxoplasma gondii cathepsin B 0.0097 0.114 1
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0013 0.0112 0.0304
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Brugia malayi Fli-1 protein 0.021 0.2509 0.7264
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0206 0.1807
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0013 0.0112 0.3945
Loa Loa (eye worm) fibroinase 0.002 0.0206 0.0459
Trypanosoma cruzi major cysteine proteinase, putative 0.0013 0.0112 0.0181
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0206 0.0578
Echinococcus granulosus GA binding protein alpha chain 0.0069 0.0797 0.2219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Onchocerca volvulus 0.002 0.0206 0.4689
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0079 0.0099
Brugia malayi cathepsin B-like cysteine proteinase 0.0286 0.3435 1
Onchocerca volvulus 0.002 0.0206 0.4689
Plasmodium vivax unspecified product 0.0013 0.0112 0.3945
Brugia malayi cathepsin L-like precursor 0.0013 0.0112 0.0181
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0097 0.114 0.3218
Echinococcus granulosus cathepsin l1 0.0013 0.0112 0.0197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0037 0.0328
Echinococcus granulosus cysteine protease 0.002 0.0206 0.0475
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0079 0.0034
Schistosoma mansoni cathepsin B (C01 family) 0.0013 0.0112 0.0304
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.002 0.0206 0.0578
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0112 0.0983
Onchocerca volvulus 0.0029 0.0312 1
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.001 0.0077 0.5
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0206 0.0475
Onchocerca volvulus Cathepsin L homolog 0.002 0.0206 0.4689
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0037 0.0328
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0079 0.0083
Plasmodium vivax unspecified product 0.002 0.0206 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.002 0.0206 0.0459
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0286 0.3435 1
Loa Loa (eye worm) cysteine protease 0.002 0.0206 0.0459
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0037 0.0328
Loa Loa (eye worm) hypothetical protein 0.0013 0.0112 0.0181
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0013 0.0112 0.0304
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0112 0.0983
Echinococcus granulosus cathepsin b 0.0286 0.3435 1
Brugia malayi cathepsin L precursor 0.0013 0.0112 0.0181
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0013 0.0112 0.3945
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0206 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0112 0.0983
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0097 0.114 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0079 0.0083
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0206 0.0459
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0067 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0206 0.1807
Echinococcus multilocularis cathepsin L 0.0013 0.0112 0.0067
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0013 0.0112 0.3945
Echinococcus multilocularis cathepsin b 0.0286 0.3435 0.3405
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0013 0.0112 0.3945
Trypanosoma cruzi cysteine proteinase, putative 0.002 0.0206 0.0459
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.002 0.0206 0.0578
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Onchocerca volvulus 0.002 0.0206 0.4689
Loa Loa (eye worm) fli-1 protein 0.021 0.2509 0.7264
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0631 0.5046
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Brugia malayi Cathepsin L-like precursor 0.002 0.0206 0.0459
Echinococcus granulosus expressed protein 0.001 0.0077 0.0093
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0013 0.0112 0.0304
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0013 0.0112 0.0181
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0523 0.1411
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0206 0.1807
Brugia malayi cathepsin L-like cysteine proteinase 0.0013 0.0112 0.0181
Treponema pallidum bacterioferrin (TpF1) 0.001 0.0077 0.5
Schistosoma mansoni ferritin light chain 0.001 0.0077 0.0201
Schistosoma mansoni cathepsin C 0.0013 0.0112 0.0304
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0013 0.0112 0.3945
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0206 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0112 0.0983
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0206 0.1807
Echinococcus granulosus cathepsin L cysteine protease 0.002 0.0206 0.0475
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0206 0.0459
Schistosoma mansoni cpg binding protein 0.0031 0.0333 0.0948
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0206 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0206 0.0162
Plasmodium vivax serine-repeat antigen (SERA) 0.0013 0.0112 0.3945
Schistosoma mansoni ferritin 0.001 0.0077 0.0201
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0013 0.0112 0.0983
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0206 0.1807
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0523 0.1504
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0013 0.0112 0.0181
Brugia malayi Ets-domain containing protein 0.001 0.0079 0.0083
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0523 0.1504
Schistosoma mansoni cathepsin s 0.0008 0.0051 0.0125
Echinococcus granulosus cathepsin L 0.002 0.0206 0.0475
Echinococcus multilocularis ferritin 0.001 0.0077 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0013 0.0112 0.0983
Echinococcus multilocularis GA binding protein alpha chain 0.0069 0.0797 0.0756
Echinococcus granulosus protein C ets 2 0.001 0.0079 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0037 0.0328
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0013 0.0112 0.0304
Schistosoma mansoni ferritin 0.001 0.0077 0.0201
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0013 0.0112 0.0304
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.0079 0.0099
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0206 0.1807
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Entamoeba histolytica cysteine proteinase 2 0.002 0.0206 1
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0013 0.0112 0.3945
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0206 0.0459
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0112 0.0983
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0013 0.0112 0.0304
Onchocerca volvulus 0.002 0.0206 0.4689
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0013 0.0112 0.0304
Schistosoma mansoni gabp alpha 0.0069 0.0797 0.2304
Trichomonas vaginalis helicase, putative 0.0007 0.0037 0.0328
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Giardia lamblia Cathepsin B precursor 0.0097 0.114 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0013 0.0112 0.0181
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0206 0.0459
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0206 0.0459
Echinococcus multilocularis expressed protein 0.001 0.0077 0.0032
Plasmodium vivax vivapain-2 0.002 0.0206 1
Trypanosoma cruzi cruzipain precursor, putative 0.002 0.0206 0.0459
Loa Loa (eye worm) hypothetical protein 0.0013 0.0112 0.0181
Schistosoma mansoni apoferritin-2 0.001 0.0077 0.0201
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.0079 0.0034
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0079 0.0083
Trypanosoma cruzi cysteine protease, putative 0.002 0.0206 0.0459
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0206 0.0459
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0013 0.0112 0.0983
Brugia malayi Cathepsin L-like precursor 0.0013 0.0112 0.0181
Echinococcus granulosus cathepsin L 0.0013 0.0112 0.0197
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0286 0.3435 1
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0079 0.0099
Echinococcus multilocularis cathepsin b 0.0286 0.3435 0.3405
Onchocerca volvulus Cathepsin F homolog 0.002 0.0206 0.4689
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0013 0.0112 0.0181
Brugia malayi Cathepsin L-like precursor 0.002 0.0206 0.0459
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0206 0.0459
Echinococcus granulosus cathepsin l1 0.002 0.0206 0.0475
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0013 0.0112 0.0304
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Entamoeba histolytica cysteine proteinase 1, putative 0.002 0.0206 1
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0206 0.0162
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0523 0.048
Echinococcus multilocularis protein C ets 2 0.001 0.0079 0.0034
Brugia malayi Ets-domain containing protein 0.0069 0.0797 0.2206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Schistosoma mansoni ferritin 0.001 0.0077 0.0201
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0286 0.3435 1
Echinococcus multilocularis cathepsin L 0.002 0.0206 0.0162
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0013 0.0112 0.0181
Plasmodium falciparum cysteine proteinase falcipain 1 0.002 0.0206 1
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0079 0.0083
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0037 0.0328
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0097 0.114 0.3303
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0037 0.0328
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0013 0.0112 0.3945
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0013 0.0112 0.0304
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0206 0.0459
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0206 1
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Schistosoma mansoni ets-related 0.021 0.2509 0.7298
Plasmodium vivax vivapain-1 0.002 0.0206 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0206 1
Echinococcus multilocularis cysteine protease 0.002 0.0206 0.0162
Loa Loa (eye worm) hypothetical protein 0.001 0.0079 0.0083
Plasmodium vivax vivapain-2 0.002 0.0206 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0112 0.0983
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0112 0.0181
Brugia malayi cathepsin F-like cysteine proteinase 0.0013 0.0112 0.0181
Schistosoma mansoni ferritin 0.001 0.0077 0.0201
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0013 0.0112 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0037 0.0328
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.001 0.0077 0.5
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.0079 0.0034
Brugia malayi fibroinase precursor 0.0013 0.0112 0.0181
Mycobacterium ulcerans bacterioferritin BfrA 0.001 0.0077 0.5
Loa Loa (eye worm) hypothetical protein 0.0013 0.0112 0.0181
Schistosoma mansoni cpg binding protein 0.0031 0.0333 0.0948
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0206 0.0459
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0037 0.0328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0206 0.1807
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0206 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Brugia malayi cathepsin Z-like cysteine proteinase 0.0013 0.0112 0.0181
Brugia malayi Papain family cysteine protease containing protein 0.0013 0.0112 0.0181
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.0079 0.0099
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0312 0.0773
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0037 0.0328
Schistosoma mansoni ets-related 0.001 0.0079 0.0207
Schistosoma mansoni apoferritin-2 0.001 0.0077 0.0201
Schistosoma mansoni hypothetical protein 0.001 0.0079 0.0207
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0286 0.3435 1
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0206 0.0162
Brugia malayi Cathepsin L-like precursor 0.002 0.0206 0.0459
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0523 0.1396
Mycobacterium ulcerans bacterioferritin BfrB 0.001 0.0077 0.5
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0206 0.0475
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0711 0.2053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0079 0.0083
Entamoeba histolytica cysteine protease, putative 0.002 0.0206 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0112 0.0983
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0065 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0013 0.0112 0.0983
Trypanosoma brucei cysteine peptidase C (CPC) 0.0097 0.114 1
Brugia malayi Cathepsin L-like precursor 0.0013 0.0112 0.0181
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0206 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0206 0.1807
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0037 0.0328
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0013 0.0112 0.0983
Loa Loa (eye worm) hypothetical protein 0.0013 0.0112 0.0181
Brugia malayi Papain family cysteine protease containing protein 0.0013 0.0112 0.0181
Trypanosoma cruzi cysteine proteinase, putative 0.002 0.0206 0.0459
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0079 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0206 0.0459
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0206 0.0578
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0206 0.0459
Loa Loa (eye worm) hypothetical protein 0.0013 0.0112 0.0181
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0037 0.0328
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0069 0.0797 0.2206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0013 0.0112 0.3945
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0045 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0112 0.0983
Echinococcus granulosus ferritin 0.001 0.0077 0.0093
Mycobacterium tuberculosis Bacterioferritin BfrB 0.001 0.0077 0.5
Loa Loa (eye worm) hypothetical protein 0.0059 0.0676 0.1846
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.0079 0.0034
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0067 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0037 0.0328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0112 0.0983
Schistosoma mansoni ets 0.001 0.0079 0.0207
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0523 0.1504
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0013 0.0112 0.0983
Brugia malayi Cathepsin L-like precursor 0.002 0.0206 0.0459
Loa Loa (eye worm) hypothetical protein 0.0013 0.0112 0.0181
Loa Loa (eye worm) hypothetical protein 0.0013 0.0112 0.0181
Onchocerca volvulus 0.002 0.0206 0.4689
Echinococcus granulosus cpg binding protein 0.0031 0.0333 0.0848
Schistosoma mansoni elf1 0.001 0.0079 0.0207
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0206 0.1807
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0037 0.0328
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Toxoplasma gondii cathepsin CPL 0.002 0.0206 0.0915
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0286 0.3435 1
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0037 0.0328
Echinococcus granulosus cathepsin b 0.0286 0.3435 1
Loa Loa (eye worm) ctsf protein 0.002 0.0206 0.0459
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.001 0.0077 0.5
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0037 0.0328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0206 0.1807
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0097 0.114 1
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0037 0.0328
Loa Loa (eye worm) hypothetical protein 0.0013 0.0112 0.0181
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0523 0.1396
Schistosoma mansoni hypothetical protein 0.001 0.0079 0.0207
Echinococcus multilocularis cpg binding protein 0.0031 0.0333 0.0289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0206 0.1807
Brugia malayi Ets-domain containing protein 0.0069 0.0797 0.2206
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0206 0.0162
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0112 0.0304
Giardia lamblia Cathepsin B precursor 0.0097 0.114 1
Schistosoma mansoni cathepsin S (C01 family) 0.0013 0.0112 0.0304
Giardia lamblia Cathepsin B precursor 0.0097 0.114 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0112 0.0181
Plasmodium vivax vivapain-3 0.002 0.0206 1
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.0079 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0112 0.0983

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.