Detailed information for compound 1160320

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 344.451 | Formula: C19H28N4O2
  • H donors: 0 H acceptors: 3 LogP: 0.64 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCN1C(=O)CCC21CCCN(CC2)C(=O)c1cccnc1)C
  • InChi: 1S/C19H28N4O2/c1-21(2)13-14-23-17(24)6-8-19(23)7-4-11-22(12-9-19)18(25)16-5-3-10-20-15-16/h3,5,10,15H,4,6-9,11-14H2,1-2H3
  • InChiKey: YLHAIUKNHROLII-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cytosolic malate dehydrogenase 0.015 0.3235 0.3188
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.003 0.0107 0.0331
Echinococcus granulosus L lactate dehydrogenase 0.014 0.298 0.2931
Trypanosoma cruzi malate dehydrogenase, putative 0.0125 0.259 0.251
Schistosoma mansoni L-lactate dehydrogenase 0.0265 0.6234 0.6193
Brugia malayi intermediate filament protein 0.0058 0.0854 0.0755
Toxoplasma gondii thioredoxin reductase 0.004 0.0376 0.0438
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.0389 0.0323
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0854 0.0755
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.1961 0.5927
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.1089 0.0992
Brugia malayi Probable malate dehydrogenase, mitochondrial precursor 0.0143 0.3059 0.2984
Toxoplasma gondii malate dehydrogenase MDH 0.0265 0.6234 1
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.1961 0.1928
Leishmania major glycosomal malate dehydrogenase 0.0143 0.3059 0.2984
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0376 0.0271
Echinococcus granulosus lactate dehydrogenase a 0.0265 0.6234 0.6207
Schistosoma mansoni carbonic anhydrase 0.0222 0.5111 0.5058
Plasmodium falciparum malate dehydrogenase 0.0265 0.6234 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.1961 0.1928
Loa Loa (eye worm) carbonic anhydrase 3 0.0409 1 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0075 0.1298 0.1943
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0222 0.5111 0.5058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Trypanosoma brucei trypanothione reductase 0.004 0.0376 0.0271
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Schistosoma mansoni hypothetical protein 0.0222 0.5111 0.5058
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0409 1 1
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.003 0.0107 0.0331
Echinococcus multilocularis carbonic anhydrase II 0.0409 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0107 0.0066
Plasmodium vivax glutathione reductase, putative 0.004 0.0376 0.0438
Echinococcus granulosus carbonic anhydrase 0.0222 0.5111 0.5077
Loa Loa (eye worm) glutathione reductase 0.004 0.0376 0.0336
Loa Loa (eye worm) hypothetical protein 0.0075 0.1298 0.1262
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0409 1 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.1961 0.1928
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Leishmania major carbonic anhydrase-like protein 0.0409 1 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.0937 0.0839
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0101 0.1961 0.6062
Echinococcus multilocularis musashi 0.0058 0.0854 0.0791
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0101 0.1961 0.5927
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.1961 0.5927
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.003 0.0107 0.0331
Chlamydia trachomatis malate dehydrogenase 0.015 0.3235 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0091 0.1707 0.5275
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0101 0.1961 0.5927
Entamoeba histolytica acyl-coA synthetase, putative 0.0101 0.1961 0.3026
Loa Loa (eye worm) AMP-binding enzyme family protein 0.003 0.0107 0.0066
Loa Loa (eye worm) hypothetical protein 0.0075 0.1298 0.1262
Echinococcus granulosus lamin 0.0058 0.0854 0.0791
Echinococcus multilocularis lactate dehydrogenase a 0.0265 0.6234 0.6207
Trypanosoma brucei malate dehydrogenase-related 0.0125 0.259 0.251
Trypanosoma cruzi mitochondrial malate dehydrogenase, putative 0.0143 0.3059 0.2984
Echinococcus multilocularis L lactate dehydrogenase B chain 0.0265 0.6234 0.6207
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0101 0.1961 0.5927
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.015 0.3235 1
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.1089 0.0992
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0222 0.5111 0.5058
Schistosoma mansoni lamin 0.0058 0.0854 0.0755
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0143 0.3059 0.2984
Brugia malayi AMP-binding enzyme family protein 0.0101 0.1961 0.1874
Echinococcus multilocularis lactate dehydrogenase a 0.0265 0.6234 0.6207
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0091 0.1707 0.5275
Loa Loa (eye worm) malate dehydrogenase 0.0143 0.3059 0.303
Plasmodium falciparum carbonic anhydrase 0.0222 0.5111 0.8168
Echinococcus granulosus carbonic anhydrase II 0.0409 1 1
Entamoeba histolytica malate dehydrogenase, putative 0.0265 0.6234 1
Echinococcus multilocularis carbonic anhydrase 0.0222 0.5111 0.5077
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.015 0.3235 0.3162
Echinococcus granulosus lactate dehydrogenase a 0.0265 0.6234 0.6207
Echinococcus multilocularis L lactate dehydrogenase 0.014 0.298 0.2931
Mycobacterium tuberculosis Probable reductase 0.0091 0.1707 0.5275
Schistosoma mansoni carbonic anhydrase-related 0.0222 0.5111 0.5058
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0101 0.1971 0.6093
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.015 0.3235 1
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.0389 0.0323
Loa Loa (eye worm) hypothetical protein 0.0075 0.1298 0.1262
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0376 0.0438
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0854 0.0817
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Echinococcus multilocularis cytosolic malate dehydrogenase 0.015 0.3235 0.3188
Entamoeba histolytica acyl-CoA synthetase, putative 0.0101 0.1961 0.3026
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0854 0.0817
Schistosoma mansoni carbonic anhydrase-related 0.0222 0.5111 0.5058
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0376 0.1161
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0107 0.0331
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0091 0.1707 0.5275
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.003 0.0107 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Plasmodium falciparum thioredoxin reductase 0.004 0.0376 0.0438
Schistosoma mansoni L-lactate dehydrogenase 0.0125 0.259 0.251
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Loa Loa (eye worm) hypothetical protein 0.0075 0.1298 0.1262
Leishmania major malate dehydrogenase, putative 0.0265 0.6234 0.6193
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.003 0.0107 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.1191 0.368
Loa Loa (eye worm) hypothetical protein 0.0028 0.0069 0.0028
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.015 0.3235 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Brugia malayi Thioredoxin reductase 0.004 0.0376 0.0271
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0107 0.0331
Schistosoma mansoni malate dehydrogenase 0.015 0.3235 0.3162
Echinococcus multilocularis malate dehydrogenase 0.0143 0.3059 0.3011
Trichomonas vaginalis malate dehydrogenase, putative 0.0086 0.1567 0.4666
Brugia malayi Malate dehydrogenase, cytoplasmic 0.015 0.3235 0.3162
Echinococcus granulosus L lactate dehydrogenase B chain 0.0265 0.6234 0.6207
Mycobacterium tuberculosis Probable dehydrogenase 0.0091 0.1707 0.5275
Leishmania major cathepsin L-like protease 0.0067 0.1089 0.0992
Mycobacterium tuberculosis Probable oxidoreductase 0.0101 0.1971 0.6093
Onchocerca volvulus 0.0058 0.0854 0.4031
Plasmodium falciparum glutathione reductase 0.004 0.0376 0.0438
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Mycobacterium leprae PROBABLE MALATE DEHYDROGENASE MDH 0.015 0.3235 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0222 0.5111 0.5058
Echinococcus multilocularis lactate dehydrogenase a 0.0265 0.6234 0.6207
Brugia malayi AMP-binding enzyme family protein 0.0101 0.1961 0.1874
Plasmodium vivax lactate dehydrogenase 0.0265 0.6234 1
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0107 0.0066
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0107 0.0331
Leishmania major malate dehydrogenase 0.0143 0.3059 0.2984
Schistosoma mansoni carbonic anhydrase-related 0.0222 0.5111 0.5058
Echinococcus multilocularis lactate dehydrogenase protein 0.0265 0.6234 0.6207
Mycobacterium ulcerans acyl-CoA synthetase 0.0101 0.1961 0.5927
Echinococcus multilocularis lamin dm0 0.0058 0.0854 0.0791
Schistosoma mansoni malate dehydrogenase 0.015 0.3235 0.3162
Echinococcus multilocularis carbonic anhydrase 0.0222 0.5111 0.5077
Trichomonas vaginalis malate dehydrogenase, putative 0.0061 0.0922 0.2604
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0075 0.1298 0.4011
Leishmania major malate dehydrogenase, putative 0.0125 0.259 0.251
Trichomonas vaginalis malate dehydrogenase, putative 0.0125 0.259 0.7937
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Echinococcus granulosus lactate dehydrogenase protein 0.0265 0.6234 0.6207
Trypanosoma cruzi malate dehydrogenase, putative 0.0143 0.3059 0.2984
Schistosoma mansoni lamin 0.0058 0.0854 0.0755
Loa Loa (eye worm) hypothetical protein 0.0075 0.1298 0.1262
Loa Loa (eye worm) hypothetical protein 0.0058 0.0854 0.0817
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.1191 0.368
Leishmania major cathepsin L-like protease 0.0067 0.1089 0.0992
Giardia lamblia Malate dehydrogenase 0.015 0.3235 0.5
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Plasmodium vivax lactate/malate dehydrogenase, putative 0.0125 0.259 0.4053
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0101 0.1971 0.6093
Trypanosoma brucei mitochondrial malate dehydrogenase 0.0143 0.3059 0.2984
Brugia malayi AMP-binding enzyme family protein 0.0101 0.1961 0.1874
Entamoeba histolytica acyl-CoA synthetase, putative 0.0101 0.1961 0.3026
Loa Loa (eye worm) hypothetical protein 0.0222 0.5111 0.5091
Entamoeba histolytica malate dehydrogenase,cytoplasmic, putative 0.015 0.3235 0.5106
Trypanosoma brucei carbonic anhydrase-like protein 0.0409 1 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0101 0.1961 0.1874
Plasmodium vivax malate dehydrogenase, putative 0.0265 0.6234 1
Toxoplasma gondii hypothetical protein 0.0222 0.5111 0.8168
Entamoeba histolytica malate dehydrogenase, putative 0.015 0.3235 0.5106
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Leishmania major mitochondrial malate dehydrogenase 0.0143 0.3059 0.2984
Echinococcus granulosus lamin dm0 0.0058 0.0854 0.0791
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0107 0.0331
Onchocerca volvulus 0.0058 0.0854 0.4031
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0101 0.1961 0.5927
Mycobacterium tuberculosis Probable malate dehydrogenase Mdh 0.015 0.3235 1
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.015 0.3235 0.3162
Loa Loa (eye worm) hypothetical protein 0.0222 0.5111 0.5091
Loa Loa (eye worm) hypothetical protein 0.0265 0.6234 0.6218
Echinococcus granulosus carbonic anhydrase 0.0222 0.5111 0.5077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.1961 0.6062
Leishmania major cathepsin L-like protease 0.0067 0.1089 0.0992
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.015 0.0109
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0091 0.1707 0.5275
Schistosoma mansoni malate dehydrogenase 0.0265 0.6234 0.6193
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.1089 0.0992
Loa Loa (eye worm) AMP-binding enzyme family protein 0.003 0.0107 0.0066
Leishmania major 4-coumarate:coa ligase-like protein 0.0101 0.1961 0.1874
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0222 0.5111 0.5091
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.003 0.0107 0.0331
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0101 0.1971 0.5959
Echinococcus granulosus malate dehydrogenase 0.0143 0.3059 0.3011
Echinococcus granulosus intermediate filament protein 0.0058 0.0854 0.0791
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0409 1 1
Echinococcus granulosus cytosolic malate dehydrogenase 0.015 0.3235 0.3188
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.015 0.3235 1
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0222 0.5111 0.5058
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.003 0.0107 0.0331
Plasmodium falciparum L-lactate dehydrogenase 0.0265 0.6234 1
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0409 1 1
Mycobacterium ulcerans hypothetical protein 0.0101 0.1961 0.5927
Loa Loa (eye worm) hypothetical protein 0.0222 0.5111 0.5091
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0222 0.5111 0.5058
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0376 0.0336
Mycobacterium ulcerans malate dehydrogenase 0.015 0.3235 1
Trypanosoma brucei glycosomal malate dehydrogenase 0.0143 0.3059 0.2984
Loa Loa (eye worm) malate dehydrogenase 0.015 0.3235 0.3207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Leishmania major 4-coumarate:coa ligase-like protein 0.0101 0.1961 0.1874
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0091 0.1707 0.5113
Echinococcus granulosus cytosolic malate dehydrogenase 0.015 0.3235 0.3188
Echinococcus granulosus malate dehydrogenase 0.0143 0.3059 0.3011
Plasmodium falciparum lactate dehydrogenase, putative 0.0125 0.259 0.4053
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0075 0.1298 0.3806
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.1089 0.0992
Toxoplasma gondii lactate dehydrogenase LDH2 0.0265 0.6234 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0714 0.0613
Schistosoma mansoni malate dehydrogenase 0.0143 0.3059 0.2984
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0143 0.3059 0.2984
Schistosoma mansoni intermediate filament proteins 0.0058 0.0854 0.0755
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0101 0.1961 0.5927
Plasmodium falciparum acyl-CoA synthetase 0.0075 0.1298 0.1943
Echinococcus multilocularis lamin 0.0058 0.0854 0.0791
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.003 0.0107 0.0331
Trypanosoma brucei cytosolic malate dehydrogenase 0.015 0.3235 0.3162
Leishmania major cytosolic malate dehydrogenase 0.015 0.3235 0.3162
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0409 1 1
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.015 0.0043
Onchocerca volvulus 0.0101 0.1961 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0827 0.0789
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.1089 0.0992
Brugia malayi lactate dehydrogenase. 0.0265 0.6234 0.6193
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.003 0.0107 0.0331
Echinococcus multilocularis malate dehydrogenase 0.0143 0.3059 0.3011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.1191 0.368
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.1191 0.368
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0101 0.1961 0.5927
Trichomonas vaginalis malate dehydrogenase, putative 0.015 0.3235 1
Wolbachia endosymbiont of Brugia malayi malate dehydrogenase 0.0265 0.6234 0.5
Toxoplasma gondii lactate dehydrogenase LDH1 0.0265 0.6234 1
Brugia malayi glutathione reductase 0.004 0.0376 0.0271
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0409 1 1
Loa Loa (eye worm) oxidoreductase 0.003 0.0107 0.0066
Leishmania major trypanothione reductase 0.004 0.0376 0.0271
Echinococcus multilocularis carbonic anhydrase 0.0222 0.5111 0.5077
Echinococcus granulosus carbonic anhydrase 0.0222 0.5111 0.5077

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.