Detailed information for compound 1346937

Basic information

Technical information
  • TDR Targets ID: 1346937
  • Name: 4-[2-[2-(4-methoxyphenyl)-5-morpholin-4-yl-1- benzofuran-3-yl]ethynyl]aniline
  • MW: 424.491 | Formula: C27H24N2O3
  • H donors: 1 H acceptors: 0 LogP: 5.05 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)c1oc2c(c1C#Cc1ccc(cc1)N)cc(cc2)N1CCOCC1
  • InChi: 1S/C27H24N2O3/c1-30-23-10-5-20(6-11-23)27-24(12-4-19-2-7-21(28)8-3-19)25-18-22(9-13-26(25)32-27)29-14-16-31-17-15-29/h2-3,5-11,13,18H,14-17,28H2,1H3
  • InChiKey: WKYLXDFSHZFFAL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[2-[2-(4-methoxyphenyl)-5-morpholino-benzofuran-3-yl]ethynyl]aniline
  • 4-[2-[2-(4-methoxyphenyl)-5-morpholino-3-benzofuranyl]ethynyl]aniline
  • [4-[2-[2-(4-methoxyphenyl)-5-morpholino-benzofuran-3-yl]ethynyl]phenyl]amine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Saccharomyces cerevisiae Rce1p Starlite/ChEMBL No references
Homo sapiens aryl hydrocarbon receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) Get druggable targets OG5_129169 All targets in OG5_129169
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K08658 prenyl protein peptidase, putative Get druggable targets OG5_129169 All targets in OG5_129169
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) Get druggable targets OG5_129169 All targets in OG5_129169
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum IPR001189,Manganese and iron superoxide dismutase,domain-containing Get druggable targets OG5_133500 All targets in OG5_133500
Echinococcus granulosus aryl hydrocarbon receptor Get druggable targets OG5_133500 All targets in OG5_133500
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K09093 aryl hydrocarbon receptor, putative Get druggable targets OG5_133500 All targets in OG5_133500
Leishmania infantum CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) Get druggable targets OG5_129169 All targets in OG5_129169
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi CAAX amino terminal protease family protein Get druggable targets OG5_129169 All targets in OG5_129169
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like Get druggable targets OG5_129169 All targets in OG5_129169
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans ras and a-factor terminal proteolysis Get druggable targets OG5_129169 All targets in OG5_129169
Schistosoma mansoni family U48 unassigned peptidase (U48 family) Get druggable targets OG5_129169 All targets in OG5_129169
Trypanosoma cruzi CAAX prenyl protease 2, putative Get druggable targets OG5_129169 All targets in OG5_129169
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) Get druggable targets OG5_129169 All targets in OG5_129169
Trypanosoma congolense CAAX amino terminal protease, putative Get druggable targets OG5_129169 All targets in OG5_129169
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Giardia lamblia Hypothetical protein Get druggable targets OG5_129169 All targets in OG5_129169
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133500 All targets in OG5_133500
Brugia malayi aryl hydrocarbon receptor AHR-1 Get druggable targets OG5_133500 All targets in OG5_133500
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129169 All targets in OG5_129169
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133500 All targets in OG5_133500
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) Get druggable targets OG5_129169 All targets in OG5_129169
Onchocerca volvulus Get druggable targets OG5_133500 All targets in OG5_133500
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus CAAX prenyl protease 2 Get druggable targets OG5_129169 All targets in OG5_129169
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni family U48 unassigned peptidase (U48 family) Get druggable targets OG5_129169 All targets in OG5_129169
Trypanosoma brucei CAAX amino terminal protease, putative Get druggable targets OG5_129169 All targets in OG5_129169
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133500 All targets in OG5_133500
Schistosoma mansoni aryl hydrocarbon receptor Get druggable targets OG5_133500 All targets in OG5_133500
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani CAAX prenyl protease 2, putative Get druggable targets OG5_129169 All targets in OG5_129169
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis aryl hydrocarbon receptor Get druggable targets OG5_133500 All targets in OG5_133500
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum expressed protein Get druggable targets OG5_129169 All targets in OG5_129169
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis CAAX prenyl protease 2 Get druggable targets OG5_129169 All targets in OG5_129169
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans ras and a-factor terminal proteolysis Get druggable targets OG5_129169 All targets in OG5_129169
Trypanosoma brucei gambiense CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48), putative Get druggable targets OG5_129169 All targets in OG5_129169
Entamoeba histolytica CAAX prenyl protease family Get druggable targets OG5_129169 All targets in OG5_129169
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.1576 0.087
Loa Loa (eye worm) hypothetical protein 0.0044 0.0898 0.0136
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0898 0.0136
Plasmodium falciparum transporter, putative 0.0044 0.0898 1
Schistosoma mansoni aryl hydrocarbon receptor 0.0213 0.8016 0.785
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0898 0.0136
Loa Loa (eye worm) serotonin transporter b 0.026 1 1
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0023 0 0.5
Loa Loa (eye worm) hypothetical protein 0.014 0.492 0.4495
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.1576 0.087
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0044 0.0898 1
Onchocerca volvulus 0.0158 0.5698 0.5273
Giardia lamblia Hypothetical protein 0.0111 0.3703 0.5
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0898 0.0136
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0044 0.0898 0.0136
Brugia malayi PAS domain containing protein 0.0073 0.2133 0.1475
Schistosoma mansoni single-minded 0.0073 0.2133 0.1475
Echinococcus granulosus serotonin transporter 0.026 1 1
Plasmodium falciparum amino acid transporter, putative 0.0044 0.0898 1
Echinococcus multilocularis aryl hydrocarbon receptor 0.0159 0.5725 0.5303
Echinococcus granulosus single minded 2 0.0054 0.1329 0.0473
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0139 0.4893 0.4466
Mycobacterium ulcerans putative regulatory protein 0.0054 0.1329 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.026 1 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0898 0.0136
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0898 0.0136
Loa Loa (eye worm) hypothetical protein 0.0044 0.0898 0.0136
Loa Loa (eye worm) hypothetical protein 0.0044 0.0898 0.0136
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0898 1
Loa Loa (eye worm) hypothetical protein 0.006 0.1576 0.087
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0898 0.0136
Trypanosoma brucei CAAX amino terminal protease, putative 0.0111 0.3703 0.5
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0898 0.0136
Brugia malayi CAAX amino terminal protease family protein 0.0111 0.3703 0.3176
Treponema pallidum sodium- and chloride- dependent transporter 0.026 1 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0898 1
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0111 0.3703 0.3176
Schistosoma mansoni hypothetical protein 0.0205 0.7665 0.747
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0898 0.0136
Toxoplasma gondii hypothetical protein 0.0044 0.0898 1
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0111 0.3703 0.5
Echinococcus multilocularis CAAX prenyl protease 2 0.0111 0.3703 0.3081
Echinococcus multilocularis geminin 0.0205 0.7665 0.7435
Echinococcus granulosus geminin 0.0205 0.7665 0.7435
Loa Loa (eye worm) norepinephrine transporter 0.026 1 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0898 0.0136
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0898 0.0136
Loa Loa (eye worm) hypothetical protein 0.0044 0.0898 0.0136
Loa Loa (eye worm) solute carrier family 6 member 4 0.026 1 1
Loa Loa (eye worm) hypothetical protein 0.026 1 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0898 0.0136
Echinococcus multilocularis serotonin transporter 0.026 1 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0898 1
Onchocerca volvulus 0.0055 0.1355 0.0502
Loa Loa (eye worm) hypothetical protein 0.0139 0.4893 0.4466
Loa Loa (eye worm) hypothetical protein 0.0111 0.3703 0.3176
Loa Loa (eye worm) hypothetical protein 0.026 1 1
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0023 0 0.5
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0111 0.3703 0.5
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0044 0.0898 0.0136
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0898 0.0136
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0898 0.0136
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0111 0.3703 0.3176
Mycobacterium tuberculosis Probable integral membrane protein 0.0023 0 0.5
Brugia malayi bHLH-PAS transcription factor 0.0054 0.1329 0.0603
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0111 0.3703 0.5
Loa Loa (eye worm) hypothetical protein 0.026 1 1
Echinococcus granulosus aryl hydrocarbon receptor 0.0159 0.5725 0.5303
Schistosoma mansoni sodium-dependent amino acid transporter 0.0044 0.0898 0.0136
Entamoeba histolytica CAAX prenyl protease family 0.0111 0.3703 1
Onchocerca volvulus 0.026 1 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0898 0.0136
Toxoplasma gondii hypothetical protein 0.0044 0.0898 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.1576 0.087
Loa Loa (eye worm) hypothetical protein 0.0158 0.5698 0.5338
Plasmodium vivax amine transporter, putative 0.0044 0.0898 1
Echinococcus multilocularis transfer RNA-Lys 0.0054 0.1329 0.0473
Loa Loa (eye worm) hypothetical protein 0.0044 0.0898 0.0136
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0898 0.0136
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0898 1
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0111 0.3703 0.5
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0898 0.0136
Schistosoma mansoni sodium/chloride dependent transporter 0.026 1 1
Echinococcus granulosus CAAX prenyl protease 2 0.0111 0.3703 0.3081
Brugia malayi hypothetical protein 0.0044 0.0898 0.0136
Schistosoma mansoni hypothetical protein 0.0205 0.7665 0.747

Activities

Activity type Activity value Assay description Source Reference
AC50 (binding) = 5.023 uM PUBCHEM_BIOASSAY: Ras-converting Enzyme/Cell Proliferation Pathway Measured in Biochemical System Using Plate Reader - 2034-01_Inhibitor_Dose_CherryPick. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2618] ChEMBL. No reference
EC50 (ADMET) = 5.719 um PUBCHEM_BIOASSAY: Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR). (Class of assay: confirmatory) [Related pubchem assays: 2796 (Primary screen (AHR activators in singlicate)), 2845 (Confirmation screen (AHR activators in triplicate)), 434939 (Counterscreen (PXR activators in triplicate)), 2804 (Summary (AHR activators))] ChEMBL. No reference
EC50 (ADMET) = 95.267 um PUBCHEM_BIOASSAY: Luminescence-based counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): cell-based high throughput dose response screening assay for activators of the Pregnane X Receptor (PXR). (Class of assay: confirmatory) [Related pubchem assays: 2796 (Primary screen (AHR activators in singlicate)), 2845 (Confirmation screen (AHR activators in triplicate)), 434939 (Counterscreen (PXR activators in triplicate)), 2804 (Summary (AHR activators))] ChEMBL. No reference
Potency (functional) 2.5929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.8048 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 16.3601 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 70.7946 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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