Detailed information for compound 1462793

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 664.71 | Formula: C34H30N7O6S+
  • H donors: 4 H acceptors: 7 LogP: 7.27 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: CN(c1ccc2c(c1)[s+]c1c(n2)cc(c(c1)N)C)C.Oc1ccc(cc1)C(=NNc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])c1ccc(cc1)O
  • InChi: 1S/C19H14N4O6.C15H16N3S/c24-15-6-1-12(2-7-15)19(13-3-8-16(25)9-4-13)21-20-17-10-5-14(22(26)27)11-18(17)23(28)29;1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13/h1-11,20,24-25H;4-8H,16H2,1-3H3/q;+1
  • InChiKey: BVFPVDCLAHRQIO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0042 0.0202 0.0179
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0142 0.1973
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Brugia malayi hypothetical protein 0.0338 0.2141 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Schistosoma mansoni ran 0.0024 0.0082 0.0268
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0098 0.1233
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0142 0.1973
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0042 0.0202 0.0956
Brugia malayi Cam kinase protein 1 0.0032 0.0139 0.0544
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0042 0.0202 0.2985
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0142 0.0118
Trypanosoma cruzi hexose transporter 0.0033 0.0142 0.0118
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.2985
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.0179
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0024 0.0056
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0126 0.0472
Plasmodium vivax importin-beta 2, putative 0.0032 0.0138 0.0398
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.0139 0.0404
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0081 0.0266
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Trypanosoma cruzi protein farnesyltransferase, putative 0.0042 0.0202 0.0179
Plasmodium falciparum hexose transporter 0.0106 0.0621 0.2094
Echinococcus granulosus importin subunit beta 1 0.0032 0.0138 0.0526
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0138 0.0609
Plasmodium vivax proline--tRNA ligase, putative 0.0037 0.0169 0.051
Loa Loa (eye worm) hypothetical protein 0.0032 0.0139 0.0586
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0142 0.1973
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.2985
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0042 0.0202 0.2985
Entamoeba histolytica hypothetical protein 0.0026 0.0098 0.1344
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.0139 0.0404
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0142 0.1973
Plasmodium vivax hexose transporter 0.0106 0.0621 0.2094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0139 0.0586
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0081 0.0308
Loa Loa (eye worm) hypothetical protein 0.0042 0.0202 0.0877
Leishmania major GTP-binding protein, putative 0.0024 0.0082 0.006
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0082 0.0058
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0042 0.0202 0.2985
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0042 0.0202 0.0826
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0082 0.0268
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0042 0.0202 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0082 0.3243
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.1973
Trypanosoma cruzi squalene monooxygenase, putative 0.0413 0.2628 0.2611
Loa Loa (eye worm) hypothetical protein 0.0338 0.2141 0.9811
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0081 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0169 0.0146
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0044 0.002
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.0135 0.0513
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0042 0.0202 0.0842
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.0135 0.0523
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0082 0.0203
Schistosoma mansoni ran 0.0024 0.0082 0.0268
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0345 0.2182 1
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.0139 0.0404
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Loa Loa (eye worm) hypothetical protein 0.0026 0.0096 0.0386
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0169 0.0146
Brugia malayi RNA, U transporter 1 0.0092 0.0527 0.2377
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0135 0.0513
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0042 0.0202 0.2985
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0142 0.0118
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0139 0.0115
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Trypanosoma brucei glucose transporter 2A 0.0033 0.0142 0.0118
Leishmania major protein kinase, putative 0.0032 0.0139 0.0119
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Leishmania major farnesyltransferase beta subunit 0.0042 0.0202 0.0184
Schistosoma mansoni glucose transport protein 0.0106 0.0621 0.2767
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0139 0.1927
Entamoeba histolytica Ran family GTPase 0.0024 0.0082 0.0035
Loa Loa (eye worm) hypothetical protein 0.0042 0.0202 0.0877
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0042 0.0202 1
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0126 0.0472
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0082 0.0058
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Loa Loa (eye worm) sugar transporter 0.0015 0.0024 0.0056
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.0139 0.0617
Loa Loa (eye worm) hypothetical protein 0.0032 0.0135 0.0566
Echinococcus granulosus snurportin 1 0.0345 0.2182 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.0139 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0142 0.1973
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0202 0.0179
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0042 0.0202 0.0826
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0138 0.0526
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0139 0.0544
Trichomonas vaginalis ran, putative 0.0024 0.0082 0.0968
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0138 0.0114
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0082 0.0273
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0098 0.1233
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Brugia malayi Importin beta-1 subunit 0.0032 0.0138 0.0537
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.0135 0.0523
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0042 0.0202 0.0842
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0024 0.2954
Schistosoma mansoni hypothetical protein 0.0345 0.2182 1
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0169 0.015
Entamoeba histolytica protein kinase, putative 0.0032 0.0139 0.4772
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0081 1
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.2985
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0042 0.0202 0.0625
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0081 0.0058
Schistosoma mansoni glucose transport protein 0.0106 0.0621 0.2767
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.1973
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0142 0.0118
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0169 0.0146
Plasmodium falciparum proline--tRNA ligase 0.0037 0.0169 0.051
Echinococcus multilocularis snurportin 1 0.0345 0.2182 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Trypanosoma brucei squalene monooxygenase, putative 0.0413 0.2628 0.2611
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0142 0.0118
Mycobacterium ulcerans sugar transporter 0.0015 0.0024 0.2954
Leishmania major glucose transporter, lmgt3 0.0033 0.0142 0.0121
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.0139 0.0404
Onchocerca volvulus 0.0338 0.2141 1
Plasmodium falciparum importin beta, putative 0.0032 0.0138 0.0398
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0081 0.0266
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0988 0.6399 1
Plasmodium vivax geranylgeranyltransferase, putative 0.0042 0.0202 0.0625
Schistosoma mansoni protein kinase 0.0032 0.0139 0.0533
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0081 0.0271
Trypanosoma cruzi squalene monooxygenase, putative 0.0413 0.2628 0.2611
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Trypanosoma cruzi lanosterol synthase, putative 0.1538 1 1
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.0142 0.0121
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0138 0.0114
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0082 0.0058
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0135 0.0513
Schistosoma mansoni glucose transport protein 0.0106 0.0621 0.2767
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0042 0.0202 0.0842
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0042 0.0202 0.0826
Schistosoma mansoni protein kinase 0.0032 0.0139 0.0533
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0042 0.0202 0.0877
Treponema pallidum prolyl-tRNA synthetase 0.0011 0 0.5
Leishmania major lanosterol synthase, putative 0.1496 0.9724 1
Schistosoma mansoni hypothetical protein 0.0106 0.0621 0.2767
Loa Loa (eye worm) sugar transporter 0.0106 0.0621 0.2808
Giardia lamblia Prenyltransferase 0.0042 0.0202 1
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.0179
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.0956
Plasmodium vivax CDK-related protein kinase 6, putative 0.045 0.2876 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0042 0.0202 1
Leishmania major importin beta-1 subunit, putative 0.0026 0.0098 0.0076
Leishmania major squalene monooxygenase-like protein 0.0413 0.2628 0.2685
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.0139 0.0404
Loa Loa (eye worm) hypothetical protein 0.0024 0.0081 0.032
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Toxoplasma gondii protein kinase, putative 0.03 0.189 1
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0139 0.0533
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0139 0.0586
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0042 0.0202 0.0625
Plasmodium falciparum mitogen-activated protein kinase 2 0.0171 0.1049 0.3595
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0042 0.0202 0.0956
Leishmania major geranylgeranyltransferase, putative 0.0042 0.0202 0.0184
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.0139 0.0404
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0082 0.0322
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0081 0.3046
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0139 0.0533
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0081 0.0201
Schistosoma mansoni protein kinase 0.0032 0.0139 0.0533
Leishmania major glucose transporter, lmgt1 0.0033 0.0142 0.0121
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0142 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0621 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0098 0.0074
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0082 0.0268
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0042 0.0202 0.0877
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.0135 0.0513
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0081 0.0201
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0082 0.0203
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0024 0.2954
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0037 0.0169 0.0779
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0042 0.0202 0.0826
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.0139 0.0617
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0042 0.0202 0.0826
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0042 0.0202 0.0625
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0042 0.0202 0.2985
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0081 0.322
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0024 0.0056
Plasmodium falciparum protein kinase 6 0.045 0.2876 1
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0142 0.0118
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.0139 0.0617
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.0135 0.4415
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.0139 0.0404
Loa Loa (eye worm) hypothetical protein 0.0032 0.0135 0.0566
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.0135 0.1855
Trypanosoma cruzi lanosterol synthase, putative 0.1538 1 1
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0042 0.0202 0.0826
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0171 0.1049 0.3595
Echinococcus multilocularis General substrate transporter 0.0091 0.0524 0.2314
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0082 0.031
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.0135 0.6214
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0171 0.1049 0.5495
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0081 0.0961
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0106 0.0621 0.2767
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0042 0.0202 0.0826
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0042 0.0202 0.0625
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0058 0.0053
Schistosoma mansoni importin beta-1 0.0032 0.0138 0.0526
Plasmodium falciparum geranylgeranyltransferase, putative 0.0042 0.0202 0.0625
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0081 0.0266
Loa Loa (eye worm) hypothetical protein 0.0032 0.0138 0.0579
Plasmodium falciparum protein kinase 7 0.03 0.189 0.6542
Toxoplasma gondii facilitative glucose transporter GT1 0.0106 0.0621 0.3201
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0042 0.0202 0.0826
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0042 0.0202 0.0826
Echinococcus granulosus General substrate transporter 0.0091 0.0524 0.2314
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0202 0.0179
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0098 0.1233
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0081 0.0058
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0169 0.015
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0058 0.0053
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0081 0.0059
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Trypanosoma cruzi protein farnesyltransferase, putative 0.0042 0.0202 0.0179
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.0135 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Trypanosoma brucei glucose transporter 1E 0.0033 0.0142 0.0118
Brugia malayi Sugar transporter family protein 0.0106 0.0621 0.2821
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.0139 0.0404
Entamoeba histolytica protein kinase, putative 0.0032 0.0139 0.4772
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0042 0.0202 0.2985
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.0081 1
Giardia lamblia Rab geranylgeranyltransferase 0.0042 0.0202 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0015 0.0024 0.5
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0062 0.0641
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0081 0.0266
Leishmania major glucose transporter, lmgt2 0.0033 0.0142 0.0121
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0024 0.2954

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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