Detailed information for compound 1462793

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 664.71 | Formula: C34H30N7O6S+
  • H donors: 4 H acceptors: 7 LogP: 7.27 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: CN(c1ccc2c(c1)[s+]c1c(n2)cc(c(c1)N)C)C.Oc1ccc(cc1)C(=NNc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])c1ccc(cc1)O
  • InChi: 1S/C19H14N4O6.C15H16N3S/c24-15-6-1-12(2-7-15)19(13-3-8-16(25)9-4-13)21-20-17-10-5-14(22(26)27)11-18(17)23(28)29;1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13/h1-11,20,24-25H;4-8H,16H2,1-3H3/q;+1
  • InChiKey: BVFPVDCLAHRQIO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein kinase, putative 0.0032 0.0139 0.4772
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0169 0.0146
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0082 0.0203
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.0956
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0139 0.0115
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0042 0.0202 0.0877
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0169 0.015
Leishmania major protein kinase, putative 0.0032 0.0139 0.0119
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0042 0.0202 0.0956
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0042 0.0202 0.0842
Trypanosoma brucei squalene monooxygenase, putative 0.0413 0.2628 0.2611
Loa Loa (eye worm) hypothetical protein 0.0338 0.2141 0.9811
Leishmania major farnesyltransferase beta subunit 0.0042 0.0202 0.0184
Schistosoma mansoni importin beta-1 0.0032 0.0138 0.0526
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.0139 0.0404
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0042 0.0202 0.0826
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0082 0.031
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.0135 0.0523
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0082 0.0268
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0098 0.1233
Entamoeba histolytica Ran family GTPase 0.0024 0.0082 0.0035
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.0081 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.0135 0.0523
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0139 0.0533
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0142 0.1973
Plasmodium falciparum mitogen-activated protein kinase 2 0.0171 0.1049 0.3595
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0139 0.1927
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0042 0.0202 0.0842
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Echinococcus granulosus importin subunit beta 1 0.0032 0.0138 0.0526
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0081 0.0271
Plasmodium falciparum importin beta, putative 0.0032 0.0138 0.0398
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Leishmania major geranylgeranyltransferase, putative 0.0042 0.0202 0.0184
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.0135 1
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0142 0.1973
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0081 0.0058
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0024 0.2954
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0138 0.0526
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.0135 0.1855
Onchocerca volvulus 0.0338 0.2141 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0042 0.0202 0.2985
Schistosoma mansoni glucose transport protein 0.0106 0.0621 0.2767
Brugia malayi RNA, U transporter 1 0.0092 0.0527 0.2377
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.0135 0.6214
Giardia lamblia Rab geranylgeranyltransferase 0.0042 0.0202 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0042 0.0202 0.2985
Loa Loa (eye worm) sugar transporter 0.0015 0.0024 0.0056
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0042 0.0202 0.0826
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0024 0.0056
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0081 0.322
Loa Loa (eye worm) hypothetical protein 0.0032 0.0138 0.0579
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0037 0.0169 0.0779
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.0139 0.0404
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0171 0.1049 0.3595
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0139 0.0586
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0042 0.0202 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0082 0.3243
Leishmania major importin beta-1 subunit, putative 0.0026 0.0098 0.0076
Mycobacterium ulcerans sugar transporter 0.0015 0.0024 0.2954
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Leishmania major glucose transporter, lmgt2 0.0033 0.0142 0.0121
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0042 0.0202 0.0826
Plasmodium falciparum protein kinase 7 0.03 0.189 0.6542
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.1973
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0082 0.0268
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0042 0.0202 0.0826
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0082 0.0058
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0081 0.0058
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0171 0.1049 0.5495
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0142 0.1973
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0082 0.0273
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.0139 0.0404
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0621 1
Plasmodium vivax importin-beta 2, putative 0.0032 0.0138 0.0398
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0081 0.0201
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.0135 0.0513
Echinococcus multilocularis General substrate transporter 0.0091 0.0524 0.2314
Loa Loa (eye worm) hypothetical protein 0.0032 0.0135 0.0566
Trypanosoma cruzi squalene monooxygenase, putative 0.0413 0.2628 0.2611
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.0179
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0081 0.0201
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.0139 0.0404
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0106 0.0621 0.2767
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0042 0.0202 1
Trypanosoma cruzi lanosterol synthase, putative 0.1538 1 1
Schistosoma mansoni protein kinase 0.0032 0.0139 0.0533
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0081 0.0266
Trypanosoma cruzi hexose transporter 0.0033 0.0142 0.0118
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.0179
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.0139 0.0404
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0142 0.0118
Leishmania major squalene monooxygenase-like protein 0.0413 0.2628 0.2685
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.0139 0.0617
Entamoeba histolytica hypothetical protein 0.0026 0.0098 0.1344
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0126 0.0472
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0042 0.0202 0.0826
Plasmodium falciparum protein kinase 6 0.045 0.2876 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0082 0.0203
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0081 0.3046
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0988 0.6399 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0081 0.0961
Brugia malayi Sugar transporter family protein 0.0106 0.0621 0.2821
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0024 0.0056
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0142 0.1973
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.0139 0.0404
Schistosoma mansoni hypothetical protein 0.0106 0.0621 0.2767
Brugia malayi Cam kinase protein 1 0.0032 0.0139 0.0544
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0042 0.0202 0.0826
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0015 0.0024 0.5
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0062 0.0641
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0142 0.0118
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0138 0.0114
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0081 1
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0139 0.0533
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0142 0.0118
Loa Loa (eye worm) hypothetical protein 0.0032 0.0139 0.0586
Giardia lamblia Prenyltransferase 0.0042 0.0202 1
Trypanosoma cruzi protein farnesyltransferase, putative 0.0042 0.0202 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.1973
Echinococcus granulosus snurportin 1 0.0345 0.2182 1
Schistosoma mansoni glucose transport protein 0.0106 0.0621 0.2767
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0042 0.0202 0.0877
Brugia malayi Importin beta-1 subunit 0.0032 0.0138 0.0537
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0042 0.0202 0.0826
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0042 0.0202 0.0625
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0081 0.0308
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0169 0.0146
Plasmodium vivax geranylgeranyltransferase, putative 0.0042 0.0202 0.0625
Plasmodium falciparum proline--tRNA ligase 0.0037 0.0169 0.051
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0082 0.0058
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0169 0.015
Schistosoma mansoni ran 0.0024 0.0082 0.0268
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0142 0.0118
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0139 0.0586
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0042 0.0202 0.0625
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0135 0.0513
Schistosoma mansoni protein kinase 0.0032 0.0139 0.0533
Loa Loa (eye worm) hypothetical protein 0.0032 0.0135 0.0566
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Schistosoma mansoni glucose transport protein 0.0106 0.0621 0.2767
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0169 0.0146
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0044 0.002
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0138 0.0609
Leishmania major GTP-binding protein, putative 0.0024 0.0082 0.006
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0098 0.1233
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0042 0.0202 0.0625
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0081 0.0266
Plasmodium vivax CDK-related protein kinase 6, putative 0.045 0.2876 1
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.2985
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Loa Loa (eye worm) hypothetical protein 0.0024 0.0081 0.032
Leishmania major glucose transporter, lmgt1 0.0033 0.0142 0.0121
Schistosoma mansoni ran 0.0024 0.0082 0.0268
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0082 0.0058
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.0621 0.2767
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0042 0.0202 0.0956
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0042 0.0202 0.0625
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0345 0.2182 1
Leishmania major lanosterol synthase, putative 0.1496 0.9724 1
Trichomonas vaginalis ran, putative 0.0024 0.0082 0.0968
Plasmodium vivax hexose transporter 0.0106 0.0621 0.2094
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0042 0.0202 0.0826
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0042 0.0202 0.0826
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0098 0.0074
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Entamoeba histolytica protein kinase, putative 0.0032 0.0139 0.4772
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0126 0.0472
Toxoplasma gondii protein kinase, putative 0.03 0.189 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0139 0.0544
Trypanosoma brucei glucose transporter 2A 0.0033 0.0142 0.0118
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Plasmodium falciparum geranylgeranyltransferase, putative 0.0042 0.0202 0.0625
Treponema pallidum prolyl-tRNA synthetase 0.0011 0 0.5
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0142 0.0118
Brugia malayi hypothetical protein 0.0338 0.2141 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.0139 0.0404
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Trypanosoma brucei glucose transporter 1E 0.0033 0.0142 0.0118
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.0139 0.0404
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.0139 0.0404
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.0135 0.0513
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0082 0.0322
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0142 0.1973
Loa Loa (eye worm) hypothetical protein 0.0026 0.0096 0.0386
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.2985
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0135 0.0513
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0024 0.2954
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0042 0.0202 0.2985
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0042 0.0202 0.2985
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0202 0.2985
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0202 0.0179
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0142 0.0118
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Schistosoma mansoni hypothetical protein 0.0345 0.2182 1
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0042 0.0202 1
Loa Loa (eye worm) sugar transporter 0.0106 0.0621 0.2808
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0042 0.0202 0.0179
Toxoplasma gondii facilitative glucose transporter GT1 0.0106 0.0621 0.3201
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.0139 0.0617
Trypanosoma cruzi lanosterol synthase, putative 0.1538 1 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0202 0.0877
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0202 0.0179
Trypanosoma brucei glucose transporter, putative 0.0033 0.0142 0.0118
Plasmodium falciparum hexose transporter 0.0106 0.0621 0.2094
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0042 0.0202 0.2985
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0098 0.1233
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.0142 0.0121
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0081 0.0059
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0081 0.0266
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0058 0.0053
Plasmodium vivax proline--tRNA ligase, putative 0.0037 0.0169 0.051
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.0139 0.0617
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0081 1
Trypanosoma cruzi protein farnesyltransferase, putative 0.0042 0.0202 0.0179
Echinococcus granulosus General substrate transporter 0.0091 0.0524 0.2314
Trypanosoma cruzi squalene monooxygenase, putative 0.0413 0.2628 0.2611
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0042 0.0202 0.2985
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.0135 0.4415
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0138 0.0114
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0081 0.0266
Loa Loa (eye worm) hypothetical protein 0.0042 0.0202 0.0877
Schistosoma mansoni protein kinase 0.0032 0.0139 0.0533
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0024 0.2954
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0058 0.0053
Echinococcus multilocularis snurportin 1 0.0345 0.2182 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0139 0.0533
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0056
Leishmania major glucose transporter, lmgt3 0.0033 0.0142 0.0121
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0042 0.0202 0.0842

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.