Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.052 | 0.7067 | 0.6563 |
Loa Loa (eye worm) | serotonin transporter b | 0.0728 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0719 | 0.9879 | 0.9877 |
Mycobacterium tuberculosis | Probable glutamine-binding lipoprotein GlnH (GLNBP) | 0.002 | 0 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0124 | 0.1465 | 0.5 |
Onchocerca volvulus | CoRest homolog | 0.052 | 0.7067 | 0.6563 |
Loa Loa (eye worm) | hypothetical protein | 0.0728 | 1 | 1 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0728 | 1 | 1 |
Echinococcus granulosus | serotonin transporter | 0.0728 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0728 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0728 | 1 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0124 | 0.1465 | 0.5 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0124 | 0.1465 | 0.1371 |
Plasmodium falciparum | transporter, putative | 0.0124 | 0.1465 | 0.5 |
Mycobacterium ulcerans | glutamine-binding lipoprotein GlnH | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0124 | 0.1465 | 0.1371 |
Plasmodium falciparum | amino acid transporter, putative | 0.0124 | 0.1465 | 0.5 |
Plasmodium vivax | amine transporter, putative | 0.0124 | 0.1465 | 0.5 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0124 | 0.1465 | 0.1371 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0124 | 0.1465 | 0.1371 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0728 | 1 | 1 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0728 | 1 | 1 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0124 | 0.1465 | 1 |
Brugia malayi | Serotonin receptor | 0.0482 | 0.6527 | 0.5931 |
Plasmodium vivax | hypothetical protein, conserved | 0.0124 | 0.1465 | 0.5 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0124 | 0.1465 | 0.5 |
Onchocerca volvulus | 0.0728 | 1 | 1 | |
Toxoplasma gondii | hypothetical protein | 0.0124 | 0.1465 | 0.5 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0728 | 1 | 1 |
Brugia malayi | Myb-like DNA-binding domain containing protein | 0.0505 | 0.6858 | 0.6319 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0124 | 0.1465 | 0.1371 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0124 | 0.1465 | 0.1371 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0124 | 0.1465 | 0.5 |
Echinococcus multilocularis | serotonin transporter | 0.0728 | 1 | 1 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0124 | 0.1465 | 0.1371 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0124 | 0.1465 | 0.1371 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0728 | 1 | 1 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0124 | 0.1465 | 0.1371 |
Loa Loa (eye worm) | hypothetical protein | 0.0505 | 0.6858 | 0.6319 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0124 | 0.1465 | 0.1371 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0124 | 0.1465 | 0.1371 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0712 | 0.9775 | 0.9772 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.