TDR Targets

Basic information

Technical information

TDR Targets ID: 1487172
Name: N-[(Z)-1-(1-ethylindol-3-yl)-3-morpholin-4-yl -3-oxoprop-1-en-2-yl]-4-methoxybenzamide
MW: 433.5 | Formula: C25H27N3O4
H donors: 1 H acceptors: 2 LogP: 2.83 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc(cc1)C(=O)N/C(=C\c1cn(c2c1cccc2)CC)/C(=O)N1CCOCC1
InChi: 1S/C25H27N3O4/c1-3-27-17-19(21-6-4-5-7-23(21)27)16-22(25(30)28-12-14-32-15-13-28)26-24(29)18-8-10-20(31-2)11-9-18/h4-11,16-17H,3,12-15H2,1-2H3,(H,26,29)/b22-16-
InChiKey: HYKAZFBLEYYXAO-JWGURIENSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

N-[(Z)-2-(1-ethylindol-3-yl)-1-(morpholine-4-carbonyl)vinyl]-4-methoxy-benzamide
N-[(Z)-2-(1-ethyl-3-indolyl)-1-(morpholino-oxomethyl)vinyl]-4-methoxybenzamide
N-[(Z)-1-(1-ethylindol-3-yl)-3-morpholin-4-yl-3-oxo-prop-1-en-2-yl]-4-methoxy-benzamide

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	SMAD family member 2	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Loa Loa (eye worm)	MH2 domain-containing protein	Get druggable targets OG5_131716	All targets in OG5_131716
Brugia malayi	MH2 domain containing protein	Get druggable targets OG5_131716	All targets in OG5_131716
Loa Loa (eye worm)	transcription factor SMAD2	Get druggable targets OG5_131716	All targets in OG5_131716

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Brugia malayi	MH2 domain containing protein	SMAD family member 2	467 aa	405 aa	31.6 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Trypanosoma cruzi	Eukaryotic initiation factor 4A-1	0.0143	0.0612	0.0612
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0289	0.2196	0.6565
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Schistosoma mansoni	cathepsin F (C01 family)	0.0203	0.1266	0.1266
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Schistosoma mansoni	cathepsin F (C01 family)	0.0289	0.2196	0.2196
Leishmania major	cathepsin L-like protease	0.0289	0.2196	0.6565
Loa Loa (eye worm)	hypothetical protein	0.0203	0.1266	0.1266
Brugia malayi	Cathepsin L-like precursor	0.0203	0.1266	0.1266
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0289	0.2196	0.6565
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Onchocerca volvulus	Cathepsin F homolog	0.0289	0.2196	1
Entamoeba histolytica	cysteine proteinase 2	0.0163	0.0832	0.1388
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0289	0.2196	0.2196
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Echinococcus multilocularis	cathepsin L cysteine protease	0.0289	0.2196	0.1687
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Entamoeba histolytica	cysteine proteinase, putative	0.0289	0.2196	1
Onchocerca volvulus		0.0289	0.2196	1
Brugia malayi	Papain family cysteine protease containing protein	0.0289	0.2196	0.2196
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0203	0.1266	0.1266
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0366	0.3025	0.3025
Onchocerca volvulus		0.0289	0.2196	1
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Leishmania major	cysteine peptidase A (CPA)	0.0289	0.2196	0.6565
Trypanosoma cruzi	cysteine protease, putative	0.0163	0.0832	0.0832
Trypanosoma cruzi	cysteine proteinase, putative	0.0163	0.0832	0.0832
Onchocerca volvulus	Cathepsin L homolog	0.0289	0.2196	1
Brugia malayi	Cathepsin L-like precursor	0.0289	0.2196	0.2196
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0366	0.3025	1
Echinococcus granulosus	cathepsin l1	0.0289	0.2196	0.1687
Leishmania major	cathepsin L-like protease	0.0289	0.2196	0.6565
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0289	0.2196	0.6565
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Mycobacterium tuberculosis	Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog)	0.0143	0.0612	0.5
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Schistosoma mansoni	cathepsin F (C01 family)	0.0289	0.2196	0.2196
Onchocerca volvulus		0.0289	0.2196	1
Trypanosoma cruzi	Eukaryotic initiation factor 4A-1	0.0143	0.0612	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0203	0.1266	0.1266
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0163	0.0832	0.0911
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0366	0.3025	1
Loa Loa (eye worm)	hypothetical protein	0.0203	0.1266	0.1266
Schistosoma mansoni	DEAD box ATP-dependent RNA helicase	0.0143	0.0612	0.0612
Treponema pallidum	ATP-dependent RNA helicase	0.0143	0.0612	0.5
Echinococcus multilocularis	cathepsin b	0.1012	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0289	0.2196	0.2196
Plasmodium vivax	vivapain-3	0.0163	0.0832	0.3787
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0289	0.2196	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0289	0.2196	0.6565
Echinococcus granulosus	cathepsin b	0.1012	1	1
Loa Loa (eye worm)	hypothetical protein	0.1012	1	1
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0163	0.0832	0.0832
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0163	0.0832	0.0832
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.1012	1	1
Entamoeba histolytica	cysteine proteinase, putative	0.0289	0.2196	1
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0289	0.2196	0.1687
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0289	0.2196	0.6565
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0289	0.2196	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0203	0.1266	0.271
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0135	0.0524	0.0524
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0366	0.3025	0.3025
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0163	0.0832	0.0911
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Leishmania major	cathepsin L-like protease	0.0289	0.2196	0.6565
Echinococcus multilocularis	cysteine protease	0.0289	0.2196	0.1687
Loa Loa (eye worm)	hypothetical protein	0.0135	0.0524	0.0524
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0289	0.2196	0.6565
Brugia malayi	Trypsin family protein	0.0135	0.0524	0.0524
Onchocerca volvulus		0.0203	0.1266	0.5446
Trypanosoma cruzi	cysteine proteinase, putative	0.0163	0.0832	0.0832
Echinococcus granulosus	cathepsin L cysteine protease	0.0163	0.0832	0.0234
Brugia malayi	Cathepsin L-like precursor	0.0289	0.2196	0.2196
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Giardia lamblia	Cathepsin B precursor	0.0366	0.3025	1
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0203	0.1266	0.1266
Trypanosoma cruzi	cysteine peptidase, putative	0.0289	0.2196	0.2196
Onchocerca volvulus	Cathepsin L homolog	0.0289	0.2196	1
Plasmodium vivax	vivapain-2	0.0289	0.2196	1
Brugia malayi	Cathepsin L-like precursor	0.0289	0.2196	0.2196
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Brugia malayi	Papain family cysteine protease containing protein	0.0163	0.0832	0.0832
Entamoeba histolytica	cysteine proteinase, putative	0.0163	0.0832	0.1388
Entamoeba histolytica	cysteine protease, putative	0.0289	0.2196	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0163	0.0832	0.0911
Brugia malayi	Papain family cysteine protease containing protein	0.0163	0.0832	0.0832
Onchocerca volvulus	Eukaryotic initiation factor 4A homolog	0.0143	0.0612	0.2244
Brugia malayi	MH2 domain containing protein	0.0144	0.0628	0.0628
Echinococcus multilocularis	cathepsin L cysteine protease	0.0289	0.2196	0.1687
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0163	0.0832	0.0832
Echinococcus granulosus	cathepsin l1	0.0203	0.1266	0.0697
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Brugia malayi	Cathepsin L-like precursor	0.0289	0.2196	0.2196
Giardia lamblia	Cathepsin B precursor	0.0366	0.3025	1
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0135	0.0524	0.0524
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0289	0.2196	0.6565
Trypanosoma cruzi	cysteine peptidase, putative	0.0289	0.2196	0.2196
Loa Loa (eye worm)	hypothetical protein	0.0135	0.0524	0.0524
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Schistosoma mansoni	DEAD box ATP-dependent RNA helicase	0.0143	0.0612	0.0612
Brugia malayi	Cathepsin L-like precursor	0.0289	0.2196	0.2196
Plasmodium vivax	RNA helicase-1, putative	0.0143	0.0612	0.2786
Leishmania major	cathepsin L-like protease	0.0289	0.2196	0.6565
Echinococcus granulosus	cysteine protease	0.0163	0.0832	0.0234
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Giardia lamblia	Cathepsin B precursor	0.0366	0.3025	1
Leishmania major	cathepsin L-like protease	0.0289	0.2196	0.6565
Brugia malayi	cathepsin L-like precursor	0.0203	0.1266	0.1266
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0163	0.0832	0.0911
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0289	0.2196	0.2196
Brugia malayi	Cathepsin L-like precursor	0.0289	0.2196	0.2196
Toxoplasma gondii	cathepsin B	0.0366	0.3025	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0203	0.1266	0.271
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Entamoeba histolytica	cysteine proteinase, putative	0.0203	0.1266	0.4128
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Onchocerca volvulus		0.0289	0.2196	1
Toxoplasma gondii	cathepsin CPL	0.0289	0.2196	0.6565
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0366	0.3025	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0289	0.2196	0.6565
Entamoeba histolytica	cysteine proteinase, putative	0.0163	0.0832	0.1388
Trypanosoma cruzi	cysteine peptidase, putative	0.0163	0.0832	0.0832
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0289	0.2196	0.1687
Loa Loa (eye worm)	ctsf protein	0.0289	0.2196	0.2196
Plasmodium vivax	vivapain-1	0.0163	0.0832	0.3787
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.1012	1	1
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Trypanosoma cruzi	cysteine peptidase, putative	0.0289	0.2196	0.2196
Trypanosoma cruzi	cruzipain precursor, putative	0.0289	0.2196	0.2196
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0289	0.2196	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Loa Loa (eye worm)	MH2 domain-containing protein	0.0144	0.0628	0.0628
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0289	0.2196	0.1687
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0289	0.2196	0.6565
Brugia malayi	Cathepsin L-like precursor	0.0203	0.1266	0.1266
Echinococcus multilocularis	cathepsin L	0.0163	0.0832	0.0234
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0289	0.2196	0.6565
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0289	0.2196	0.1687
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Loa Loa (eye worm)	hypothetical protein	0.0289	0.2196	0.2196
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0163	0.0832	0.0832
Entamoeba histolytica	cysteine proteinase, putative	0.0163	0.0832	0.1388
Echinococcus multilocularis	cathepsin b	0.1012	1	1
Brugia malayi	eukaryotic initiation factor 4A	0.0143	0.0612	0.0612
Echinococcus granulosus	cathepsin b	0.1012	1	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.1012	1	1
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0163	0.0832	0.1388
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Entamoeba histolytica	cysteine proteinase, putative	0.0163	0.0832	0.1388
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Loa Loa (eye worm)	fibroinase	0.0289	0.2196	0.2196
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.1012	1	1
Loa Loa (eye worm)	hypothetical protein	0.0143	0.0612	0.0612
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Loa Loa (eye worm)	transcription factor SMAD2	0.0144	0.0628	0.0628
Plasmodium vivax	vivapain-2	0.0289	0.2196	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Echinococcus granulosus	cathepsin L	0.0163	0.0832	0.0234
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0289	0.2196	0.6565
Leishmania major	cathepsin L-like protease	0.0289	0.2196	0.6565
Loa Loa (eye worm)	cathepsin B	0.0366	0.3025	0.3025
Plasmodium vivax	unspecified product	0.0163	0.0832	0.3787
Onchocerca volvulus		0.0289	0.2196	1
Onchocerca volvulus		0.0135	0.0524	0.1813
Leishmania major	cathepsin L-like protease	0.0289	0.2196	0.6565
Echinococcus multilocularis	cysteine protease	0.0289	0.2196	0.1687
Loa Loa (eye worm)	cysteine protease	0.0289	0.2196	0.2196
Entamoeba histolytica	cysteine protease, putative	0.0163	0.0832	0.1388
Onchocerca volvulus		0.0289	0.2196	1
Entamoeba histolytica	cysteine proteinase 1, putative	0.0163	0.0832	0.1388
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0289	0.2196	0.6565
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Onchocerca volvulus		0.0289	0.2196	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.1012	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0289	0.2196	0.6565
Leishmania major	cathepsin L-like protease	0.0289	0.2196	0.6565

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	0.0828 uM	PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850]	ChEMBL.	No reference
Potency (functional)	6.3096 uM	PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860]	ChEMBL.	No reference
Potency (functional)	11.6891 uM	PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850]	ChEMBL.	No reference
Potency (functional)	25.929 uM	PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	89.1251 uM	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391]	ChEMBL.	No reference
Potency (functional)	100 uM	PUBCHEM_BIOASSAY: Inhibitors of TCP-1 ring complex (TRiC) of Methanococcus maripaludis (MmCpn): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488991]	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Plasmodium falciparum	ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1719797

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1487172