Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0394 | 0.3347 | 0.7547 |
Echinococcus granulosus | contactin | 0.029 | 0.1675 | 0.3778 |
Schistosoma mansoni | hemicentin | 0.0234 | 0.0776 | 0.1779 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.029 | 0.1675 | 0.1759 |
Onchocerca volvulus | 0.0234 | 0.0776 | 1 | |
Echinococcus granulosus | Down syndrome cell adhesion molecule | 0.0241 | 0.09 | 0.2029 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.029 | 0.1675 | 0.3778 |
Schistosoma mansoni | cell adhesion molecule | 0.029 | 0.1675 | 0.3843 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.078 | 0.9522 | 1 |
Echinococcus multilocularis | roundabout 2 | 0.0462 | 0.4435 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0241 | 0.09 | 0.0945 |
Onchocerca volvulus | 0.0234 | 0.0776 | 1 | |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.029 | 0.1675 | 0.3778 |
Loa Loa (eye worm) | projectin | 0.0234 | 0.0776 | 0.0815 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0234 | 0.0776 | 0.0776 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0234 | 0.0776 | 0.0776 |
Echinococcus granulosus | roundabout 2 | 0.029 | 0.1675 | 0.3778 |
Schistosoma mansoni | myosin-binding protein-related | 0.0234 | 0.0776 | 0.1779 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0241 | 0.09 | 0.09 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0394 | 0.3347 | 0.7547 |
Schistosoma mansoni | cell adhesion molecule | 0.0234 | 0.0776 | 0.1779 |
Echinococcus granulosus | nephrin | 0.0234 | 0.0776 | 0.1749 |
Schistosoma mansoni | cell adhesion molecule | 0.0234 | 0.0776 | 0.1779 |
Schistosoma mansoni | hypothetical protein | 0.0234 | 0.0776 | 0.1779 |
Loa Loa (eye worm) | CAMK protein kinase | 0.0234 | 0.0776 | 0.0815 |
Echinococcus multilocularis | titin | 0.0234 | 0.0776 | 0.1749 |
Echinococcus multilocularis | roundabout 2 | 0.029 | 0.1675 | 0.3778 |
Echinococcus granulosus | titin | 0.0234 | 0.0776 | 0.1749 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0358 | 0.2759 | 0.2759 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.029 | 0.1675 | 0.3778 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0234 | 0.0776 | 0.0776 |
Schistosoma mansoni | neuroglian | 0.029 | 0.1675 | 0.3843 |
Echinococcus granulosus | titin | 0.0234 | 0.0776 | 0.1749 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0234 | 0.0776 | 0.0776 |
Echinococcus multilocularis | roundabout 2 | 0.029 | 0.1675 | 0.3778 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0458 | 0.436 | 0.9831 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0234 | 0.0776 | 0.1779 |
Echinococcus granulosus | twitchin | 0.0221 | 0.0573 | 0.1292 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0234 | 0.0776 | 0.0815 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0358 | 0.2759 | 0.2759 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.029 | 0.1675 | 0.3778 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.029 | 0.1675 | 0.1675 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.078 | 0.9522 | 0.9522 |
Schistosoma mansoni | nephrin | 0.0406 | 0.3535 | 0.8108 |
Brugia malayi | hypothetical protein | 0.0358 | 0.2759 | 0.2759 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.0776 | 0.0815 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0242 | 0.0904 | 0.2039 |
Loa Loa (eye worm) | hypothetical protein | 0.0358 | 0.2759 | 0.2898 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1473 | 0.1546 |
Echinococcus granulosus | neuroglian | 0.0221 | 0.0573 | 0.1292 |
Schistosoma mansoni | cell adhesion molecule | 0.029 | 0.1675 | 0.3843 |
Schistosoma mansoni | thyroid hormone receptor | 0.0458 | 0.436 | 1 |
Schistosoma mansoni | ephrin receptor | 0.0242 | 0.0904 | 0.2074 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0285 | 0.1601 | 0.1601 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0234 | 0.0776 | 0.0776 |
Brugia malayi | protein unc-22 | 0.0234 | 0.0776 | 0.0776 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0234 | 0.0776 | 0.0815 |
Echinococcus multilocularis | neuroglian | 0.029 | 0.1675 | 0.3778 |
Echinococcus multilocularis | neuroglian | 0.0221 | 0.0573 | 0.1292 |
Schistosoma mansoni | thyroid hormone receptor | 0.0458 | 0.436 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.029 | 0.1675 | 0.1759 |
Schistosoma mansoni | titin | 0.0234 | 0.0776 | 0.1779 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.0776 | 0.0815 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0234 | 0.0776 | 0.0815 |
Echinococcus granulosus | neuroglian | 0.029 | 0.1675 | 0.3778 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0234 | 0.0776 | 0.0815 |
Loa Loa (eye worm) | hypothetical protein | 0.0358 | 0.2759 | 0.2898 |
Echinococcus multilocularis | transfer RNA-Phe | 0.0234 | 0.0776 | 0.1749 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.029 | 0.1675 | 0.1675 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0234 | 0.0776 | 0.1749 |
Schistosoma mansoni | cell adhesion molecule | 0.0414 | 0.3659 | 0.8392 |
Loa Loa (eye worm) | hypothetical protein | 0.0358 | 0.2759 | 0.2898 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0285 | 0.1601 | 0.1681 |
Echinococcus multilocularis | Down syndrome cell adhesion molecule | 0.0241 | 0.09 | 0.2029 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0242 | 0.0904 | 0.2039 |
Schistosoma mansoni | nephrin | 0.029 | 0.1675 | 0.3843 |
Schistosoma mansoni | titin | 0.0234 | 0.0776 | 0.1779 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.029 | 0.1675 | 0.3778 |
Loa Loa (eye worm) | hypothetical protein | 0.0777 | 0.9465 | 0.994 |
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.1675 | 0.1759 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0234 | 0.0776 | 0.0776 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.078 | 0.9522 | 0.9522 |
Schistosoma mansoni | hypothetical protein | 0.0394 | 0.3347 | 0.7677 |
Onchocerca volvulus | 0.0234 | 0.0776 | 1 | |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.029 | 0.1675 | 0.1675 |
Echinococcus granulosus | roundabout 2 | 0.0462 | 0.4435 | 1 |
Echinococcus granulosus | roundabout 2 | 0.029 | 0.1675 | 0.3778 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.0697 | 0.0732 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0234 | 0.0776 | 0.0776 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0229 | 0.0697 | 0.1571 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.029 | 0.1675 | 0.3843 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1473 | 0.1546 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.