TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 552.442 | Formula: C19H41IN2O8
H donors: 1 H acceptors: 1 LogP: -0.03 Rotable bonds: 23
Rule of 5 violations (Lipinski): 2
SMILES: COCCOCCOCCOCCOCCOCCOC(=O)NCC[N+](C)(C)C.[I-]
InChi: 1S/C19H40N2O8.HI/c1-21(2,3)6-5-20-19(22)29-18-17-28-16-15-27-14-13-26-12-11-25-10-9-24-8-7-23-4;/h5-18H2,1-4H3;1H
InChiKey: XGWKKJHXQLTIQR-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	beta adrenergic receptor kinase	0.0019	0.0356	0.0356
Loa Loa (eye worm)	TYRA-2 protein	0.0053	0.1214	0.2007
Schistosoma mansoni	steroid hormone receptor ad4bp	0.001	0.0132	0.0132
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0356	0.0589
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0053	0.1214	0.2007
Echinococcus multilocularis	Regulator of G protein signaling 20	0.0019	0.0356	0.0356
Brugia malayi	hypothetical protein	0.0019	0.0356	0.0589
Echinococcus multilocularis	expressed protein	0.0369	0.9115	0.9115
Echinococcus multilocularis	regulator of G protein signaling 3	0.0019	0.0356	0.0356
Brugia malayi	nuclear hormone receptor	0.001	0.0132	0.0218
Schistosoma mansoni	ap endonuclease	0.0019	0.0347	0.0347
Brugia malayi	PXA domain containing protein	0.0019	0.0356	0.0589
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0014	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0014	0.0023
Loa Loa (eye worm)	hypothetical protein	0.004	0.0879	0.1454
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0054	0.1228	0.1545
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.001	0.0132	0.0132
Echinococcus multilocularis	neuropeptide s receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0014	0.0023
Brugia malayi	Dopamine receptor protein 1	0.0053	0.1214	0.2007
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0018	0.0344	0.0568
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0053	0.1221	0.1221
Loa Loa (eye worm)	hypothetical protein	0.001	0.0132	0.0218
Echinococcus granulosus	A kinase anchor protein 10 mitochondrial	0.0019	0.0356	0.0356
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Brugia malayi	hypothetical protein	0.0053	0.1214	0.2007
Entamoeba histolytica	hypothetical protein	0.0041	0.0905	0.0979
Schistosoma mansoni	biogenic amine receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0356	0.0589
Schistosoma mansoni	amine GPCR	0.0053	0.1214	0.1214
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.1214	0.1214
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0053	0.1214	0.1214
Leishmania major	basic transcription factor 3a, putative	0.0041	0.0905	0.0979
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0053	0.1214	0.1214
Brugia malayi	AKH receptor	0.0053	0.1214	0.2007
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.001	0.0132	0.0218
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.001	0.0132	0.0132
Schistosoma mansoni	growth hormone secretagogue receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0356	0.0589
Trypanosoma cruzi	transcription factor btf3, putative	0.0041	0.0905	0.0979
Brugia malayi	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus granulosus	neuropeptide receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0053	0.1214	0.1214
Brugia malayi	Latrophilin receptor protein 2	0.0018	0.0344	0.0568
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.001	0.0132	0.0218
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.1214	0.1214
Echinococcus granulosus	tm gpcr rhodopsin	0.0053	0.1214	0.1214
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0028	0.0592	0.098
Schistosoma mansoni	regulator of G protein signaling	0.0019	0.0356	0.0356
Entamoeba histolytica	prenyl cysteine carboxyl methyltransferase, putative	0.0246	0.6048	1
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0053	0.1214	0.2007
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.001	0.0132	0.0218
Onchocerca volvulus		0.0053	0.1214	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.001	0.0132	0.0218
Schistosoma mansoni	regulator of G protein signaling	0.0019	0.0356	0.0356
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.001	0.0132	0.1088
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.001	0.0132	0.0132
Onchocerca volvulus		0.001	0.0132	0.1088
Plasmodium vivax	basic transcription factor 3b, putative	0.0041	0.0905	0.0979
Schistosoma mansoni	thyroid hormone receptor	0.001	0.0132	0.0132
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0053	0.1214	1
Brugia malayi	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	hypothetical protein	0.0018	0.0344	0.0344
Echinococcus granulosus	regulator of G protein signaling 3	0.0019	0.0356	0.0356
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.001	0.0132	0.0132
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0053	0.1214	0.1214
Brugia malayi	Melatonin receptor type 1A	0.0053	0.1214	0.2007
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.001	0.0132	0.0132
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0053	0.1214	0.2007
Onchocerca volvulus	Bile acid receptor homolog	0.001	0.0132	0.1088
Schistosoma mansoni	cpg binding protein	0.003	0.0633	0.0633
Schistosoma mansoni	amine GPCR	0.0053	0.1214	0.1214
Echinococcus granulosus	hypothetical protein	0.0053	0.1214	0.1214
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	G-protein coupled receptor	0.0053	0.1214	0.2007
Echinococcus granulosus	regulator of G protein signaling 3	0.0019	0.0356	0.0356
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0019	0.0347	0.0574
Schistosoma mansoni	ap endonuclease	0.0019	0.0347	0.0347
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0018	0.0344	0.0344
Echinococcus multilocularis	serotonin receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	neuropeptide receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0053	0.1221	0.1221
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0018	0.0344	0.0344
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.0019	0.0356	0.0589
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Schistosoma mansoni	regulator of G protein signaling	0.0019	0.0356	0.0356
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0356	0.0589
Echinococcus granulosus	transcription factor btf3	0.0041	0.0905	0.0905
Trichomonas vaginalis	regulator of G protein signaling 5, rgs5, putative	0.0019	0.0356	0.0522
Schistosoma mansoni	serine/threonine protein kinase	0.0019	0.0356	0.0356
Schistosoma mansoni	cpg binding protein	0.003	0.0633	0.0633
Schistosoma mansoni	hypothetical protein	0.0198	0.4841	0.4841
Brugia malayi	PXA domain containing protein	0.0019	0.0356	0.0589
Schistosoma mansoni	regulator of G protein signaling	0.0019	0.0356	0.0356
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.001	0.0132	0.0218
Onchocerca volvulus		0.0053	0.1214	1
Trichomonas vaginalis	conserved hypothetical protein	0.0019	0.0356	0.0522
Echinococcus multilocularis	G protein coupled receptor 139	0.0053	0.1214	0.1214
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0053	0.1221	0.2018
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	neuropeptide receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	hypothetical protein	0.0198	0.4841	0.4841
Schistosoma mansoni	biogenic amine receptor	0.0053	0.1214	0.1214
Giardia lamblia	Isoprenylcysteine carboxyl methyltransferase	0.0246	0.6048	1
Echinococcus granulosus	neuropeptide s receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	axis inhibition protein axin	0.0019	0.0356	0.0356
Schistosoma mansoni	hypothetical protein	0.0018	0.0344	0.0344
Brugia malayi	Steroid receptor seven-up type 2	0.001	0.0132	0.0218
Echinococcus granulosus	biogenic amine 5HT receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Trypanosoma brucei	transcription factor BTF3, putative	0.0041	0.0905	0.0979
Echinococcus granulosus	geminin	0.0198	0.4841	0.4841
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	adenoreceptor	0.0053	0.1214	0.1214
Brugia malayi	latrophilin 2 splice variant baaae	0.004	0.0879	0.1454
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.001	0.0132	0.0132
Trypanosoma cruzi	prenyl protein specific carboxyl methyltransferase, putative	0.0246	0.6048	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0053	0.1214	0.2007
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0019	0.0356	0.0356
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0053	0.1214	0.1214
Echinococcus granulosus	expressed protein	0.0369	0.9115	0.9115
Schistosoma mansoni	amine GPCR	0.0053	0.1214	0.1214
Brugia malayi	nuclear receptor NHR-88	0.001	0.0132	0.0218
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.001	0.0132	0.0218
Echinococcus multilocularis		0.0246	0.6048	0.6048
Echinococcus multilocularis	transcription factor btf3	0.0041	0.0905	0.0905
Brugia malayi	photoreceptor-specific nuclear receptor	0.001	0.0132	0.0218
Echinococcus multilocularis	serotonin receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	neuropeptide FF receptor 2	0.0053	0.1214	0.1214
Echinococcus multilocularis	neuropeptides capa receptor	0.0053	0.1214	0.1214
Brugia malayi	G protein-coupled receptor F59B2.13	0.0053	0.1214	0.2007
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.001	0.0132	0.0218
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0053	0.1214	0.2007
Echinococcus multilocularis	geminin	0.0198	0.4841	0.4841
Toxoplasma gondii	isoprenylcysteine carboxyl methyltransferase (icmt) family protein	0.0246	0.6048	1
Entamoeba histolytica	hypothetical protein	0.0019	0.0356	0.0016
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.001	0.0132	0.0218
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Brugia malayi	G-protein coupled receptor	0.0053	0.1214	0.2007
Echinococcus granulosus	neuropeptide receptor A26	0.0053	0.1214	0.1214
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.001	0.0132	0.0218
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus granulosus	G protein coupled receptor 139	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.001	0.0132	0.0218
Toxoplasma gondii	NAC domain-containing protein	0.0041	0.0905	0.0979
Entamoeba histolytica	hypothetical protein	0.0019	0.0356	0.0016
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	g protein coupled receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.001	0.0132	0.0132
Schistosoma mansoni	hypothetical protein	0.0053	0.1214	0.1214
Schistosoma mansoni	nuclear hormone receptor	0.001	0.0132	0.0132
Echinococcus granulosus	mixed lineage leukemia protein mll	0.0007	0.0059	0.0059
Echinococcus multilocularis	dro:myosuppressin receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.1214	0.1214
Echinococcus multilocularis	FTZ F1 alpha	0.001	0.0132	0.0132
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus granulosus	7TM GPCR rhodopsin	0.0053	0.1214	0.1214
Trichomonas vaginalis	conserved hypothetical protein	0.0041	0.0905	0.1436
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0007	0.0059	0.0059
Schistosoma mansoni	hypothetical protein	0.004	0.0879	0.0879
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0014	0.0023
Echinococcus multilocularis	neuropeptide receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	histone methyltransferase	0.0009	0.0102	0.0168
Onchocerca volvulus		0.0028	0.0592	0.4882
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0053	0.1214	0.1214
Echinococcus granulosus	g protein coupled receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.001	0.0132	0.0132
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	neuropeptide receptor A26	0.0053	0.1214	0.1214
Echinococcus granulosus	ecdysone induced protein 78C	0.001	0.0132	0.0132
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0053	0.1214	0.2007
Loa Loa (eye worm)	ICD-1 protein	0.0041	0.0905	0.1497
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.001	0.0132	0.0218
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.001	0.0132	0.0132
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.001	0.0132	0.0218
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0009	0.0102	0.0102
Echinococcus granulosus	regulator of G protein signaling 7	0.0019	0.0356	0.0356
Schistosoma mansoni	axis inhibition protein axin	0.0019	0.0356	0.0356
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.001	0.0132	0.0132
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Brugia malayi	regulator of G-protein signaling rgs-7	0.0019	0.0356	0.0589
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0356	0.0589
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0053	0.1214	0.1214
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0058	0.1341	0.2217
Echinococcus multilocularis	regulator of G protein signaling 7	0.0019	0.0356	0.0356
Brugia malayi	putative neuropeptide receptor	0.0053	0.1214	0.2007
Schistosoma mansoni	regulator of G protein signaling 3 rgs3	0.0019	0.0356	0.0356
Schistosoma mansoni	hypothetical protein	0.0018	0.0344	0.0344
Schistosoma mansoni	neuropeptide receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	z-protein (S1r protein)	0.0019	0.0356	0.0356
Brugia malayi	GnHR receptor homolog	0.0053	0.1214	0.2007
Plasmodium falciparum	basic transcription factor 3b, putative	0.0041	0.0905	0.0979
Loa Loa (eye worm)	hypothetical protein	0.001	0.0132	0.0218
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0019	0.0356	0.0589
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Mycobacterium tuberculosis	Conserved hypothetical membrane protein	0.0108	0.2574	1
Schistosoma mansoni	retinoic acid receptor RXR	0.001	0.0132	0.0132
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0009	0.0102	0.0102
Echinococcus granulosus	tm gpcr rhodopsin	0.0053	0.1214	0.1214
Brugia malayi	RE15519p	0.0053	0.1214	0.2007
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	neuropeptide receptor	0.0053	0.1214	0.1214
Entamoeba histolytica	hypothetical protein	0.0019	0.0356	0.0016
Echinococcus multilocularis	GPCR, family 2	0.0018	0.0344	0.0344
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.001	0.0132	0.0218
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.001	0.0132	0.0218
Echinococcus multilocularis	allatostatin A receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0053	0.1221	0.1221
Schistosoma mansoni	cpg binding protein	0.0028	0.0592	0.0592
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0053	0.1214	0.1214
Echinococcus multilocularis	ecdysone induced protein 78C	0.001	0.0132	0.0132
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0058	0.1341	0.2217
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0014	0.0023
Trichomonas vaginalis	conserved hypothetical protein	0.0019	0.0356	0.0522
Echinococcus granulosus	axis inhibition protein axin	0.0019	0.0356	0.0356
Schistosoma mansoni	neuropeptide F-like receptor	0.0053	0.1214	0.1214
Brugia malayi	putative neuropeptide receptor NPR1	0.0053	0.1214	0.2007
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.001	0.0132	0.0218
Schistosoma mansoni	thyroid hormone receptor	0.001	0.0132	0.0132
Brugia malayi	Serotonin receptor	0.0053	0.1214	0.2007
Echinococcus granulosus	Regulator of G protein signaling 20	0.0019	0.0356	0.0356
Echinococcus multilocularis	g protein coupled receptor	0.0053	0.1214	0.1214
Brugia malayi	Serotonin receptor	0.0053	0.1214	0.2007
Plasmodium vivax	protein-S-isoprenylcysteine O-methyltransferase, putative	0.0246	0.6048	1
Brugia malayi	G-protein coupled receptor	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Trichomonas vaginalis	conserved hypothetical protein	0.0041	0.0905	0.1436
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0053	0.1214	0.1214
Onchocerca volvulus		0.0053	0.1214	1
Loa Loa (eye worm)	RGS-3 protein	0.0019	0.0356	0.0589
Echinococcus multilocularis	g-protein coupled receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	sex peptide receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	regulator of G protein signaling 3	0.0019	0.0356	0.0356
Echinococcus granulosus	dro:myosuppressin receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	beta-adrenergic receptor kinase	0.0019	0.0356	0.0356
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0007	0.0059	0.0059
Brugia malayi	hypothetical protein	0.0053	0.1214	0.2007
Brugia malayi	neuropeptide F receptor	0.0053	0.1214	0.2007
Trichomonas vaginalis	protein-S isoprenylcysteine O-methyltransferase, putative	0.0246	0.6048	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	hypothetical protein	0.0018	0.0344	0.0344
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	protein-S isoprenylcysteine O-methyltransferase	0.0246	0.6048	1
Entamoeba histolytica	transcription factor BTF3, putative	0.0041	0.0905	0.0979
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0356	0.0589
Trichomonas vaginalis	conserved hypothetical protein	0.0041	0.0905	0.1436
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	opsin-like receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	neuropeptide Y receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	protein-s-isoprenylcysteine o-methyltransferase	0.0246	0.6048	0.6048
Brugia malayi	hypothetical protein	0.0053	0.1214	0.2007
Onchocerca volvulus		0.0053	0.1214	1
Echinococcus multilocularis	regulator of G protein signaling 7	0.0019	0.0356	0.0356
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.1214	0.1214
Brugia malayi	hypothetical protein	0.0053	0.1214	0.2007
Entamoeba histolytica	prenyl cysteine carboxyl methyltransferase, putative	0.0246	0.6048	1
Echinococcus granulosus	serotonin receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0019	0.0356	0.0356
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0053	0.1214	0.1214
Brugia malayi	CXXC zinc finger family protein	0.0028	0.0592	0.098
Echinococcus multilocularis	cpg binding protein	0.003	0.0633	0.0633
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.001	0.0132	0.0218
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.001	0.0132	0.0132
Loa Loa (eye worm)	PXA domain-containing protein	0.0019	0.0356	0.0589
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	steroid hormone receptor	0.001	0.0132	0.0218
Trichomonas vaginalis	protein-S isoprenylcysteine O-methyltransferase, putative	0.0246	0.6048	1
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0053	0.1214	0.1214
Trichomonas vaginalis	conserved hypothetical protein	0.0019	0.0356	0.0522
Echinococcus granulosus	GPCR family 2	0.0018	0.0344	0.0344
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.006	0.1389	0.1389
Echinococcus granulosus	biogenic amine 5HT receptor	0.0053	0.1214	0.1214
Brugia malayi	steroid hormone receptor	0.001	0.0132	0.0218
Echinococcus multilocularis	A kinase anchor protein 10, mitochondrial	0.0019	0.0356	0.0356
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0019	0.0347	0.0347
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0053	0.1214	0.2007
Echinococcus granulosus	neuropeptides capa receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Schistosoma mansoni	regulator of G protein signaling	0.0019	0.0356	0.0356
Schistosoma mansoni	histamine h1 receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	tm gpcr rhodopsin	0.0053	0.1214	0.1214
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.001	0.0132	0.0218
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.0019	0.0356	0.0589
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Trypanosoma cruzi	transcription factor btf3, putative	0.0041	0.0905	0.0979
Echinococcus multilocularis	mixed lineage leukemia protein mll	0.0007	0.0059	0.0059
Echinococcus granulosus	regulator of G protein signaling 7	0.0019	0.0356	0.0356
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0053	0.1214	0.1214
Onchocerca volvulus		0.0053	0.1214	1
Brugia malayi	ecdysteroid receptor	0.001	0.0132	0.0218
Brugia malayi	sulfakinin receptor protein	0.0053	0.1214	0.2007
Brugia malayi	follicle stimulating hormone receptor	0.0053	0.1214	0.2007
Onchocerca volvulus		0.0053	0.1214	1
Leishmania major	prenyl protein specific carboxyl methyltransferase, putative	0.0246	0.6048	1
Brugia malayi	nuclear receptor RXR	0.0005	0.0014	0.0023
Schistosoma mansoni	neuropeptide F-like receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	g protein coupled receptor	0.0053	0.1214	0.1214
Trichomonas vaginalis	conserved hypothetical protein	0.0019	0.0356	0.0522
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.001	0.0132	0.0132
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0053	0.1214	0.2007
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.1214	0.1214
Onchocerca volvulus		0.0053	0.1214	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0053	0.1214	0.1214
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.001	0.0132	0.0218
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0019	0.0356	0.0589
Trichomonas vaginalis	conserved hypothetical protein	0.0019	0.0356	0.0522
Echinococcus granulosus	cpg binding protein	0.003	0.0633	0.0633
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus multilocularis	orexin receptor type 2	0.0053	0.1214	0.1214
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0053	0.1214	0.2007
Schistosoma mansoni	hypothetical protein	0.0053	0.1214	0.1214
Onchocerca volvulus		0.0053	0.1214	1
Brugia malayi	neuropeptide F receptor	0.0053	0.1214	0.2007
Schistosoma mansoni	hypothetical protein	0.0053	0.1214	0.1214
Brugia malayi	protein-S isoprenylcysteine O-methyltransferase, putative	0.0246	0.6048	1
Echinococcus multilocularis	neuropeptide Y receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	neuropeptide Y receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.001	0.0132	0.0132
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0053	0.1214	0.1214
Onchocerca volvulus		0.0053	0.1214	1
Echinococcus granulosus	protein S isoprenylcysteine O methyltransferase	0.0246	0.6048	0.6048
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0053	0.1221	0.1221
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0053	0.1221	0.1221
Brugia malayi	Dopamine receptor protein 2	0.0053	0.1214	0.2007
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0053	0.1221	0.1221
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.001	0.0132	0.0132
Onchocerca volvulus		0.0053	0.1214	1
Schistosoma mansoni	opsin-like receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.0019	0.0356	0.0589
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Schistosoma mansoni	RAR-like nuclear receptor	0.001	0.0132	0.0132
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0007	0.0059	0.0059
Onchocerca volvulus		0.0053	0.1214	1
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0053	0.1214	0.1214
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.1214	0.1214
Echinococcus multilocularis	fmrfamide receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	myosin xvIII	0.0053	0.1214	0.1214
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0018	0.0344	0.0344
Brugia malayi	Nuclear hormone receptor-like 1	0.001	0.0132	0.0218
Trichomonas vaginalis	protein-S isoprenylcysteine O-methyltransferase, putative	0.0246	0.6048	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Schistosoma mansoni	serine/threonine protein kinase	0.0019	0.0356	0.0356
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Brugia malayi	hypothetical protein	0.0005	0.0014	0.0023
Trypanosoma brucei	prenyl protein specific carboxyl methyltransferase	0.0246	0.6048	1
Brugia malayi	hypothetical protein	0.0053	0.1214	0.2007
Brugia malayi	F/Y-rich N-terminus family protein	0.0009	0.0099	0.0164
Loa Loa (eye worm)	melatonin receptor type 1A	0.0053	0.1214	0.2007
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.001	0.0132	0.0132
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.1214	0.1214
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0005	0.0014	0.0014
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0018	0.0344	0.0568
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.001	0.0132	0.0132
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0019	0.0347	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.1214	0.1214
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	allatostatin A receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	coup transcription factor	0.001	0.0132	0.0132
Brugia malayi	A-kinase anchor protein 10, precursor	0.0019	0.0356	0.0589
Brugia malayi	larval opioid receptor	0.0053	0.1214	0.2007
Schistosoma mansoni	neuropeptide f receptor 76f	0.0053	0.1214	0.1214
Echinococcus multilocularis	axis inhibition protein axin	0.0019	0.0356	0.0356
Schistosoma mansoni	neuropeptide receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0005	0.0014	0.0023
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.001	0.0132	0.0218
Echinococcus granulosus	neuropeptides capa receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	fmrfamide receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	neuropeptide receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	dnaJ subfamily B	0.0404	1	1
Onchocerca volvulus		0.0053	0.1214	1
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0053	0.1214	0.1214
Echinococcus multilocularis	regulator of G protein signaling	0.0019	0.0356	0.0356
Schistosoma mansoni	axis inhibition protein axin	0.0019	0.0356	0.0356
Schistosoma mansoni	hypothetical protein	0.0404	1	1
Brugia malayi	Nuclear hormone receptor-like 1	0.0005	0.0014	0.0023
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0053	0.1214	1
Echinococcus multilocularis	neuropeptide Y receptor	0.0053	0.1214	0.1214
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.001	0.0132	0.0218
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.001	0.0132	0.0218
Brugia malayi	beta-NAC-like protein	0.0041	0.0905	0.1497
Mycobacterium ulcerans	hypothetical protein	0.0108	0.2574	1
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.0019	0.0356	0.0589
Brugia malayi	Dopamine receptor	0.0053	0.1214	0.2007
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.001	0.0132	0.0132
Onchocerca volvulus	Protein ultraspiracle homolog	0.001	0.0132	0.1088
Echinococcus granulosus	orexin receptor type 2	0.0053	0.1214	0.1214
Schistosoma mansoni	amine GPCR	0.0053	0.1214	0.1214
Onchocerca volvulus		0.0053	0.1214	1
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0019	0.0347	0.5
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0053	0.1214	0.1214
Echinococcus granulosus	somatostatin receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Trypanosoma cruzi	prenyl protein specific carboxyl methyltransferase, putative	0.0246	0.6048	1
Loa Loa (eye worm)	hypothetical protein	0.001	0.0132	0.0218
Brugia malayi	hypothetical protein	0.0005	0.0014	0.0023
Loa Loa (eye worm)	G-protein coupled receptor	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0344	0.0568
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	biogenic amine receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	neuropeptide F receptor	0.0053	0.1214	0.2007
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Echinococcus multilocularis	neuropeptides capa receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	somatostatin receptor	0.0053	0.1214	0.1214
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0053	0.1221	0.2018
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0053	0.1221	0.1221
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	opsin-like receptor	0.0053	0.1214	0.1214
Onchocerca volvulus		0.0053	0.1214	1
Echinococcus granulosus	g protein coupled receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus granulosus	g-protein coupled receptor	0.0053	0.1214	0.1214
Onchocerca volvulus		0.0053	0.1214	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0053	0.1214	0.1214
Echinococcus granulosus	FTZ F1 alpha	0.001	0.0132	0.0132
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Brugia malayi	hypothetical protein	0.0053	0.1214	0.2007
Trichomonas vaginalis	ap endonuclease, putative	0.0019	0.0347	0.0507
Brugia malayi	regulator of G-protein signaling egl-10	0.0019	0.0356	0.0589
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Trichomonas vaginalis	ap endonuclease, putative	0.0019	0.0347	0.0507
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0053	0.1214	0.1214
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.001	0.0132	0.0218
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0053	0.1214	0.1214
Schistosoma mansoni	transcription factor btf3	0.0041	0.0905	0.0905
Brugia malayi	hypothetical protein	0.0053	0.1214	0.2007
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0058	0.1341	0.2217
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0053	0.1214	0.1214
Trichomonas vaginalis	conserved hypothetical protein	0.0019	0.0356	0.0522
Brugia malayi	ORL1-like opioid receptor	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.001	0.0132	0.0218
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0005	0.0014	0.0014
Echinococcus granulosus	sex peptide receptor	0.0053	0.1214	0.1214
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0053	0.1214	0.1214
Brugia malayi	hypothetical protein	0.0019	0.0356	0.0589
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Echinococcus granulosus	fmrfamide receptor	0.0053	0.1214	0.1214
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0019	0.0347	0.0347
Schistosoma mansoni	serine/threonine protein kinase	0.0019	0.0356	0.0356
Schistosoma mansoni	hypothetical protein	0.0053	0.1214	0.1214
Brugia malayi	G protein-coupled receptor	0.0053	0.1214	0.2007
Echinococcus multilocularis	g protein coupled receptor	0.0053	0.1214	0.1214
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0053	0.1214	0.2007
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Onchocerca volvulus		0.0053	0.1214	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0018	0.0344	0.0344
Brugia malayi	Nuclear hormone receptor-like 1	0.0005	0.0014	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0058	0.1341	0.2217
Plasmodium falciparum	protein-S-isoprenylcysteine O-methyltransferase, putative	0.0246	0.6048	1
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.001	0.0132	0.0132
Schistosoma mansoni	amine GPCR	0.0053	0.1214	0.1214
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0005	0.0014	0.0014
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0005	0.0014	0.0014
Loa Loa (eye worm)	hypothetical protein	0.001	0.0132	0.0218
Echinococcus granulosus	7tm_1 domain containing protein	0.0053	0.1214	0.1214
Echinococcus multilocularis	thyroid hormone receptor alpha	0.001	0.0132	0.0132
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1214	0.2007
Brugia malayi	exodeoxyribonuclease III family protein	0.0019	0.0347	0.0574
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.1214	0.1214
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0053	0.1214	0.1214
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.001	0.0132	0.0132
Echinococcus multilocularis	axis inhibition protein axin	0.0019	0.0356	0.0356
Brugia malayi	hypothetical protein	0.0053	0.1214	0.2007
Onchocerca volvulus		0.0053	0.1214	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.1214	0.1214
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.001	0.0132	0.0218

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1785000

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1528378