Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0124 | 0.1465 | 0.1371 |
Echinococcus multilocularis | serotonin transporter | 0.0728 | 1 | 1 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0124 | 0.1465 | 0.1371 |
Loa Loa (eye worm) | hypothetical protein | 0.0505 | 0.6858 | 0.6319 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0124 | 0.1465 | 0.1371 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0124 | 0.1465 | 0.1371 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0728 | 1 | 1 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0712 | 0.9775 | 0.9772 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0124 | 0.1465 | 0.1371 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0728 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0124 | 0.1465 | 0.5 |
Brugia malayi | Myb-like DNA-binding domain containing protein | 0.0505 | 0.6858 | 0.6319 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0124 | 0.1465 | 0.1371 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0124 | 0.1465 | 0.1371 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0124 | 0.1465 | 0.5 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0124 | 0.1465 | 0.1371 |
Loa Loa (eye worm) | hypothetical protein | 0.0728 | 1 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0124 | 0.1465 | 0.5 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0728 | 1 | 1 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0124 | 0.1465 | 0.1371 |
Plasmodium vivax | amine transporter, putative | 0.0124 | 0.1465 | 0.5 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0124 | 0.1465 | 0.1371 |
Mycobacterium ulcerans | glutamine-binding lipoprotein GlnH | 0.002 | 0 | 0.5 |
Plasmodium falciparum | transporter, putative | 0.0124 | 0.1465 | 0.5 |
Plasmodium falciparum | amino acid transporter, putative | 0.0124 | 0.1465 | 0.5 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0124 | 0.1465 | 0.1371 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0728 | 1 | 1 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0124 | 0.1465 | 1 |
Onchocerca volvulus | 0.0728 | 1 | 1 | |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0124 | 0.1465 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0124 | 0.1465 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0482 | 0.6527 | 0.5931 |
Echinococcus granulosus | hypothetical protein | 0.0719 | 0.9879 | 0.9877 |
Loa Loa (eye worm) | hypothetical protein | 0.052 | 0.7067 | 0.6563 |
Loa Loa (eye worm) | serotonin transporter b | 0.0728 | 1 | 1 |
Onchocerca volvulus | CoRest homolog | 0.052 | 0.7067 | 0.6563 |
Mycobacterium tuberculosis | Probable glutamine-binding lipoprotein GlnH (GLNBP) | 0.002 | 0 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0124 | 0.1465 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0728 | 1 | 1 |
Echinococcus granulosus | serotonin transporter | 0.0728 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0728 | 1 | 1 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0728 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.