TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 316.35 | Formula: C14H24N2O6
H donors: 4 H acceptors: 6 LogP: 0.92 Rotable bonds: 13
Rule of 5 violations (Lipinski): 1
SMILES: CCCCCCC(C(=O)O)NC(=O)[C@@H](NC(=O)C)CC(=O)O
InChi: 1S/C14H24N2O6/c1-3-4-5-6-7-10(14(21)22)16-13(20)11(8-12(18)19)15-9(2)17/h10-11H,3-8H2,1-2H3,(H,15,17)(H,16,20)(H,18,19)(H,21,22)/t10?,11-/m0/s1
InChiKey: KOIPURIEXQHWOB-DTIOYNMSSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	DNA topoisomerase 2 alpha	0.0137	0.2985	0.8124
Trypanosoma brucei	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Brugia malayi	hypothetical protein	0.0035	0.0589	0.156
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0033	0.0538	0.1421
Trypanosoma cruzi	lysyl-tRNA synthetase, putative	0.0023	0.0297	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0482	0.1337
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0015	0.0122	0.021
Plasmodium vivax	calcium-dependent protein kinase 1, putative	0.0031	0.0497	0.0497
Brugia malayi	Calcium/calmodulin-dependent protein kinase type II alpha chain	0.0031	0.0497	0.1269
Trypanosoma brucei	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0538	0.1512
Entamoeba histolytica	hypothetical protein	0.0097	0.2042	0.2436
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0102	0.2171	0.5894
Trypanosoma brucei	DNA polymerase IV, putative	0.0059	0.1152	0.1711
Brugia malayi	hypothetical protein	0.0025	0.034	0.0771
Schistosoma mansoni	ap endonuclease	0.0018	0.0192	0.0524
Mycobacterium ulcerans	fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT	0.0014	0.0097	0.0283
Mycobacterium ulcerans	DNA polymerase IV	0.0059	0.1152	0.3357
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0023	0.0297	0.0864
Echinococcus multilocularis	calcium dependent protein kinase	0.0029	0.0451	0.1183
Schistosoma mansoni	protein kinase	0.0031	0.0497	0.1354
Trichomonas vaginalis	conserved hypothetical protein	0.0032	0.0506	0.1416
Entamoeba histolytica	DNA topoisomerase II, putative	0.0137	0.2985	0.3679
Brugia malayi	Bifunctional aminoacyl-tRNA synthetase	0.0031	0.0482	0.1221
Echinococcus granulosus	solute carrier family 22	0.0014	0.0097	0.0214
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0506	0.0752
Schistosoma mansoni	glucose transport protein	0.0102	0.2171	0.5915
Trypanosoma brucei	bifunctional aminoacyl-tRNA synthetase, putative	0.0036	0.0602	0.0894
Trypanosoma brucei	PAB1-binding protein , putative	0.0025	0.034	0.0505
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0506	0.0752
Chlamydia trachomatis	DNA gyrase subunit A	0.0029	0.0452	0.2696
Mycobacterium ulcerans	integral membrane transport protein	0.0014	0.0097	0.0283
Schistosoma mansoni	sugar transporter	0.0014	0.0097	0.0265
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0482	0.1337
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type 1	0.0031	0.0497	0.1309
Toxoplasma gondii	prolyl-tRNA synthetase (ProRS)	0.0036	0.0602	0.0915
Giardia lamblia	Prolyl-tRNA synthetase	0.0031	0.0482	0.0619
Loa Loa (eye worm)	hypothetical protein	0.0056	0.1071	0.3182
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0102	0.2171	0.5894
Plasmodium vivax	calcium-dependent protein kinase, putative	0.0031	0.0497	0.0497
Toxoplasma gondii	calcium-dependent protein kinase CDPK3	0.0031	0.0497	0.0756
Loa Loa (eye worm)	sugar transporter	0.0014	0.0097	0.0132
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0506	0.0752
Brugia malayi	CHE-14 protein	0.0041	0.0734	0.202
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0051	0.0953	0.1416
Echinococcus multilocularis	transient receptor potential gamma protein	0.0095	0.1999	0.5423
Trypanosoma cruzi	hexose transporter	0.0032	0.0506	0.0752
Mycobacterium leprae	Possible lysyl-tRNA synthetase 2 LysX	0.0023	0.0297	0.213
Schistosoma mansoni	hypothetical protein	0.004	0.0698	0.1903
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0036	0.0602	0.0894
Trypanosoma brucei	calcium/calmodulin-dependent protein kinase, putative	0.0031	0.0497	0.0738
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0018	0.0192	0.0615
Loa Loa (eye worm)	hypothetical protein	0.0148	0.3247	1
Giardia lamblia	DNA topoisomerase II	0.013	0.2817	0.3619
Echinococcus multilocularis	flap endonuclease 1	0.0025	0.0359	0.0932
Mycobacterium ulcerans	DNA polymerase IV	0.0059	0.1152	0.3357
Plasmodium falciparum	hexose transporter	0.0102	0.2171	0.2171
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0592	0.168
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0102	0.2171	0.5894
Echinococcus granulosus	dna polymerase kappa	0.0059	0.1152	0.3102
Toxoplasma gondii	hypothetical protein	0.0048	0.0883	0.1342
Schistosoma mansoni	NADP-specific isocitrate dehydrogenase	0.0015	0.0123	0.0334
Schistosoma mansoni	hypothetical protein	0.0015	0.0122	0.0333
Schistosoma mansoni	transcription factor LCR-F1	0.0035	0.0589	0.1604
Toxoplasma gondii	ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein	0.008	0.164	0.2494
Schistosoma mansoni	hypothetical protein	0.0015	0.0122	0.0333
Mycobacterium tuberculosis	DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase)	0.0029	0.0452	0.1064
Echinococcus multilocularis	short transient receptor potential channel 6	0.0063	0.124	0.3345
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Toxoplasma gondii	transporter, major facilitator family protein	0.0014	0.0097	0.0148
Plasmodium falciparum	lysine--tRNA ligase	0.0023	0.0297	0.0297
Trypanosoma cruzi	isocitrate dehydrogenase, putative	0.0015	0.0123	0.0182
Trypanosoma brucei	DNA polymerase IV, putative	0.0053	0.0999	0.1485
Trypanosoma brucei	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Trichomonas vaginalis	ap endonuclease, putative	0.0018	0.0192	0.0329
Trypanosoma brucei	flap endonuclease-1 (FEN-1), putative	0.0025	0.0359	0.0534
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Loa Loa (eye worm)	flap endonuclease-1	0.0025	0.0359	0.0953
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0953	0.2813
Echinococcus granulosus	short transient receptor potential channel 6	0.0063	0.124	0.3345
Trichomonas vaginalis	sugar transporter, putative	0.0032	0.0506	0.1416
Toxoplasma gondii	calcium-dependent protein kinase CDPK2B	0.0031	0.0497	0.0756
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.034	0.0505
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0023	0.0297	0.0864
Schistosoma mansoni	patched 1	0.0041	0.0734	0.1998
Trichomonas vaginalis	CAMK family protein kinase	0.0031	0.0497	0.1384
Plasmodium vivax	hexose transporter	0.0102	0.2171	0.2171
Echinococcus granulosus	synaptic vesicle 2 protein	0.0014	0.0097	0.0214
Trypanosoma brucei	DNA topoisomerase II alpha, putative	0.0129	0.2811	0.4176
Mycobacterium leprae	Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase)	0.0036	0.0597	1
Plasmodium falciparum	calcium-dependent protein kinase 2	0.0031	0.0497	0.0497
Plasmodium vivax	isocitrate dehydrogenase [NADP], mitochondrial, putative	0.0015	0.0123	0.0123
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0033	0.0538	0.1465
Trichomonas vaginalis	sugar transporter, putative	0.0032	0.0506	0.1416
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Schistosoma mansoni	protein kinase	0.0031	0.0497	0.1354
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0097	0.0214
Chlamydia trachomatis	DNA gyrase subunit B	0.0063	0.1245	0.7571
Leishmania major	hypothetical protein, conserved	0.0025	0.034	0.0505
Echinococcus granulosus	short transient receptor potential channel 6	0.0063	0.124	0.3345
Echinococcus granulosus	Protein patched homolog 1	0.0041	0.0734	0.1957
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0032	0.0506	0.0752
Echinococcus multilocularis	sterol regulatory element binding protein	0.0041	0.0734	0.1957
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0033	0.0538	0.1465
Leishmania major	myo-inositol/proton symporter (MIT)	0.0014	0.0097	0.0144
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0035	0.0589	0.156
Schistosoma mansoni	nuclear transcription factor X-box binding 1 (nfx1)	0.0014	0.0097	0.0265
Onchocerca volvulus	Putative DNA topoisomerase 2, mitochondrial	0.0092	0.1939	0.5847
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0156	0.3431	1
Schistosoma mansoni	transient receptor potential channel	0.0095	0.1999	0.5446
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0032	0.0506	0.0752
Schistosoma mansoni	hypothetical protein	0.004	0.0698	0.1903
Plasmodium vivax	ataxin-2 like protein, putative	0.0025	0.034	0.034
Trypanosoma cruzi	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.0015	0.0123	0.0182
Entamoeba histolytica	prolyl-tRNA synthetase, putative	0.0031	0.0482	0.0382
Plasmodium falciparum	isocitrate dehydrogenase [NADP], mitochondrial	0.0015	0.0123	0.0123
Loa Loa (eye worm)	hypothetical protein	0.006	0.1166	0.3479
Echinococcus granulosus	geminin	0.0166	0.3671	1
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.0102	0.2171	0.5894
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 2 LysX	0.0019	0.0215	0.0354
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0497	0.1309
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.034	0.0505
Entamoeba histolytica	hypothetical protein	0.0035	0.0589	0.0522
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0014	0.0097	0.0132
Leishmania major	glucose transporter/membrane transporter D2, putative	0.0032	0.0506	0.0752
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0497	0.1384
Schistosoma mansoni	sugar transporter	0.0014	0.0097	0.0265
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0909	0.2675
Brugia malayi	DNA gyrase/topoisomerase IV, A subunit family protein	0.0137	0.2985	0.9169
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0018	0.0192	0.0286
Echinococcus granulosus	lysyl tRNA synthetase	0.0023	0.0297	0.076
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0031	0.0497	0.1309
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0202	0.0459
Schistosoma mansoni	hypothetical protein	0.0011	0.0019	0.0052
Leishmania major	flap endonuclease-1 (FEN-1), putative	0.0025	0.0359	0.0534
Plasmodium falciparum	DNA topoisomerase 2	0.0137	0.2985	0.2985
Loa Loa (eye worm)	calcium/calmodulin-dependent protein kinase ID	0.0031	0.0497	0.1384
Brugia malayi	ImpB/MucB/SamB family protein	0.0033	0.0538	0.1399
Echinococcus multilocularis	DNA topoisomerase 2 alpha	0.0137	0.2985	0.8124
Brugia malayi	Sugar transporter family protein	0.0102	0.2171	0.6584
Brugia malayi	Flap endonuclease-1	0.0025	0.0359	0.0832
Leishmania major	mitochondrial DNA topoisomerase II	0.0154	0.3381	0.5022
Toxoplasma gondii	protein kinase, putative	0.0289	0.6576	1
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0033	0.0538	0.1421
Trypanosoma brucei	lysyl-tRNA synthetase, putative	0.0023	0.0297	0.0441
Entamoeba histolytica	deoxycytidyl transferase, putative	0.0033	0.0538	0.0455
Toxoplasma gondii	sugar transporter ST3	0.0014	0.0097	0.0148
Toxoplasma gondii	facilitative glucose transporter GT1	0.0102	0.2171	0.3302
Toxoplasma gondii	sugar transporter ST1	0.0014	0.0097	0.0148
Trypanosoma brucei	DNA topoisomerase II beta, putative	0.0129	0.2811	0.4176
Echinococcus multilocularis	lysyl tRNA synthetase	0.0023	0.0297	0.076
Entamoeba histolytica	DNA repair and recombination protein RAD52, putative	0.034	0.7785	1
Plasmodium falciparum	protein kinase 7	0.0289	0.6576	0.6576
Leishmania major	DNA topoisomerase ii	0.0129	0.2811	0.4176
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Brugia malayi	Niemann-Pick C1 protein precursor	0.0096	0.2031	0.614
Toxoplasma gondii	cell-cycle-associated protein kinase MAPK, putative	0.0165	0.3657	0.5562
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0102	0.2171	0.5894
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0297	0.0756
Echinococcus granulosus	solute carrier family 22	0.0014	0.0097	0.0214
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0506	0.0752
Echinococcus granulosus	sterol regulatory element binding protein	0.0041	0.0734	0.1957
Schistosoma mansoni	hypothetical protein	0.0015	0.0122	0.0333
Echinococcus granulosus	Niemann Pick C1 protein	0.0096	0.2031	0.5511
Plasmodium falciparum	DNA gyrase subunit A	0.0029	0.0452	0.0452
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Giardia lamblia	DINP protein human, muc B family	0.004	0.069	0.0886
Plasmodium vivax	calcium-dependent protein kinase 3, putative	0.0031	0.0497	0.0497
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0506	0.0752
Echinococcus multilocularis	synaptic vesicle 2 protein	0.0014	0.0097	0.0214
Echinococcus multilocularis	protein dispatched 1	0.0047	0.0871	0.2334
Plasmodium falciparum	mitogen-activated protein kinase 2	0.0165	0.3657	0.3657
Loa Loa (eye worm)	hypothetical protein	0.0056	0.1071	0.3182
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0545	0.1534
Schistosoma mansoni	glucose transport protein	0.0102	0.2171	0.5915
Trypanosoma cruzi	hexose transporter, putative	0.0032	0.0506	0.0752
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0015	0.0122	0.0283
Treponema pallidum	DNA gyrase, subunit B (gyrB)	0.008	0.164	1
Toxoplasma gondii	sugar transporter ST2	0.0014	0.0097	0.0148
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0102	0.2171	0.5894
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0015	0.0122	0.0079
Mycobacterium tuberculosis	Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP)	0.0015	0.0123	0.0076
Mycobacterium tuberculosis	Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))	0.004	0.069	0.1778
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0015	0.0122	0.0283
Loa Loa (eye worm)	CAMK/CAMK2 protein kinase	0.0031	0.0497	0.1384
Plasmodium falciparum	flap endonuclease 1	0.0025	0.0359	0.0359
Trypanosoma brucei	DNA polymerase kappa, putative	0.0029	0.0448	0.0666
Toxoplasma gondii	DNA gyrase/topoisomerase IV, A subunit domain-containing protein	0.0029	0.0452	0.0688
Trypanosoma cruzi	mitochondrial DNA topoisomerase II, putative	0.0154	0.3381	0.5022
Chlamydia trachomatis	lysine--tRNA ligase	0.0023	0.0297	0.174
Trypanosoma cruzi	mitochondrial DNA topoisomerase II, putative	0.0154	0.3381	0.5022
Loa Loa (eye worm)	transcription factor SMAD2	0.0117	0.2515	0.7705
Leishmania major	DNA polymerase kappa, putative	0.004	0.069	0.1025
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.034	0.034
Trypanosoma brucei	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0059	0.1152	0.3651
Leishmania major	protein kinase, putative	0.0031	0.0497	0.0738
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0097	0.0214
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0031	0.0482	0.1313
Brugia malayi	isocitrate dehydrogenase	0.0015	0.0123	0.0081
Trypanosoma brucei	isocitrate dehydrogenase, putative	0.0015	0.0123	0.0182
Echinococcus multilocularis	TRP (transient receptor potential) channel	0.0035	0.0592	0.1568
Schistosoma mansoni	flap endonuclease-1	0.0023	0.0302	0.0821
Plasmodium vivax	proline--tRNA ligase, putative	0.0036	0.0602	0.0602
Plasmodium falciparum	calcium-dependent protein kinase 4	0.0031	0.0497	0.0497
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0097	0.0214
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0497	0.1309
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0018	0.0192	0.1098
Trichomonas vaginalis	ap endonuclease, putative	0.0018	0.0192	0.0329
Echinococcus multilocularis	short transient receptor potential channel 6	0.0063	0.124	0.3345
Leishmania major	mitochondrial DNA polymerase beta	0.0296	0.6732	1
Trypanosoma cruzi	DNA topoisomerase II, putative	0.0129	0.2811	0.4176
Mycobacterium leprae	Probable prolyl tRNA synthetase ProS	0.0031	0.0482	0.6992
Plasmodium falciparum	DNA gyrase subunit B	0.008	0.164	0.164
Schistosoma mansoni	hypothetical protein	0.0015	0.0122	0.0333
Schistosoma mansoni	transient receptor potential channel	0.0063	0.124	0.3379
Plasmodium vivax	DNA gyrase subunit B, putative	0.008	0.164	0.164
Loa Loa (eye worm)	sugar transporter	0.0102	0.2171	0.6629
Schistosoma mansoni	DNA topoisomerase II	0.0137	0.2985	0.8133
Echinococcus granulosus	solute carrier family 22	0.0014	0.0097	0.0214
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Mycobacterium ulcerans	DNA gyrase subunit B	0.008	0.164	0.478
Schistosoma mansoni	transient receptor potential channel 4	0.0095	0.1999	0.5446
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.034	0.034
Trypanosoma brucei	DNA polymerase kappa, putative	0.0029	0.0448	0.0666
Schistosoma mansoni	lysyl-tRNA synthetase	0.0023	0.0297	0.0808
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0032	0.0506	0.0752
Loa Loa (eye worm)	TOPoisomerase family member	0.0137	0.2985	0.918
Trypanosoma cruzi	hexose transporter, putative	0.0032	0.0506	0.0752
Echinococcus granulosus	TRP transient receptor potential channel	0.0035	0.0592	0.1568
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Trypanosoma cruzi	DNA polymerase beta thumb, putative	0.0042	0.0739	0.1097
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0018	0.0192	0.0429
Toxoplasma gondii	isocitrate dehydrogenase	0.0015	0.0123	0.0187
Brugia malayi	lysyl-tRNA synthetase	0.0023	0.0297	0.0633
Schistosoma mansoni	niemann-pick C1 (NPC1)	0.0098	0.2066	0.563
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0018	0.0192	0.0286
Brugia malayi	hypothetical protein	0.0148	0.3247	1
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0097	0.0214
Echinococcus granulosus	expressed conserved protein	0.009	0.1893	0.5133
Entamoeba histolytica	hypothetical protein	0.0023	0.0297	0.0137
Onchocerca volvulus	DNA topoisomerase 2 homolog	0.0092	0.1939	0.5847
Echinococcus multilocularis	GPCR, family 2	0.0015	0.0122	0.0283
Echinococcus granulosus	dna polymerase eta	0.0033	0.0538	0.1421
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0015	0.0123	0.0284
Onchocerca volvulus		0.0148	0.3247	1
Schistosoma mansoni	hypothetical protein	0.0102	0.2171	0.5915
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0614	0.1751
Plasmodium vivax	CDK-related protein kinase 6, putative	0.0434	1	1
Schistosoma mansoni	DNA polymerase eta	0.0033	0.0538	0.1465
Echinococcus multilocularis	isocitrate dehydrogenase	0.0015	0.0123	0.0284
Echinococcus granulosus	Niemann Pick C1 protein	0.0138	0.3007	0.8182
Trichomonas vaginalis	glucose transporter, putative	0.0032	0.0506	0.1416
Leishmania major	glucose transporter, lmgt1	0.0032	0.0506	0.0752
Plasmodium falciparum	major facilitator superfamily domain-containing protein, putative	0.0014	0.0097	0.0097
Entamoeba histolytica	protein kinase, putative	0.0031	0.0497	0.0401
Schistosoma mansoni	hypothetical protein	0.0166	0.3671	1
Wolbachia endosymbiont of Brugia malayi	DNA gyrase subunit A	0.0029	0.0452	0.23
Echinococcus multilocularis	Sugar transporter ERD6 protein	0.0014	0.0097	0.0214
Schistosoma mansoni	transient receptor potential channel	0.0063	0.124	0.3379
Trypanosoma brucei	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	0.0015	0.0123	0.0284
Plasmodium falciparum	calcium-dependent protein kinase 1	0.0031	0.0497	0.0497
Trypanosoma brucei	DNA polymerase eta, putative	0.0033	0.0538	0.0799
Entamoeba histolytica	protein kinase, putative	0.0031	0.0497	0.0401
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0018	0.0192	0.0247
Trichomonas vaginalis	prolyl-tRNA synthetase, putative	0.0031	0.0482	0.1332
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0497	0.1309
Echinococcus granulosus	Sugar transporter ERD6 protein	0.0014	0.0097	0.0214
Schistosoma mansoni	hypothetical protein	0.0166	0.3671	1
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.002	0.023	0.046
Toxoplasma gondii	BRCA1 C Terminus (BRCT) domain-containing protein	0.0017	0.0152	0.0232
Trypanosoma cruzi	sugar transporter, putative	0.0014	0.0097	0.0144
Trypanosoma cruzi	DNA polymerase beta thumb, putative	0.0042	0.0739	0.1097
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0296	0.6732	1
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0506	0.0752
Plasmodium vivax	sugar transporter, putative	0.0014	0.0097	0.0097
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0018	0.0192	0.0474
Leishmania major	DNA polymerase eta, putative	0.0033	0.0538	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0346	0.0912
Schistosoma mansoni	hypothetical protein	0.004	0.0698	0.1903
Schistosoma mansoni	hypothetical protein	0.004	0.0698	0.1903
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0018	0.0192	0.0192
Trichomonas vaginalis	glucose transporter, putative	0.0032	0.0506	0.1416
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0018	0.0192	0.0285
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0023	0.0297	0.069
Leishmania major	glucose transporter, lmgt2	0.0032	0.0506	0.0752
Leishmania major	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.0015	0.0123	0.0182
Trypanosoma cruzi	hexose transporter, putative	0.0032	0.0506	0.0752
Plasmodium vivax	mitogen-activated protein kinase 2, putative	0.0165	0.3657	0.3657
Giardia lamblia	Flap structure-specific endonuclease	0.0025	0.0359	0.0461
Schistosoma mansoni	hypothetical protein	0.0035	0.0589	0.1604
Loa Loa (eye worm)	hypothetical protein	0.0025	0.034	0.0892
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0015	0.0123	0.0284
Trichomonas vaginalis	conserved hypothetical protein	0.0102	0.2171	0.718
Brugia malayi	Isocitrate dehydrogenase	0.0015	0.0123	0.0081
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0031	0.0497	0.1309
Echinococcus granulosus	glutamyl tRNA synthetase cytoplasmic	0.0031	0.0482	0.1268
Mycobacterium tuberculosis	DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase)	0.008	0.164	0.4627
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.0019	0.0215	0.0354
Echinococcus granulosus	transient receptor potential gamma protein	0.0095	0.1999	0.5423
Echinococcus granulosus	flap endonuclease 1	0.0025	0.0359	0.0932
Loa Loa (eye worm)	hypothetical protein	0.0095	0.1999	0.609
Entamoeba histolytica	Flap nuclease, putative	0.0025	0.0359	0.022
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0036	0.0602	0.0894
Loa Loa (eye worm)	isocitrate dehydrogenase	0.0015	0.0123	0.0212
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0035	0.0589	0.156
Echinococcus granulosus	calcium dependent protein kinase	0.0029	0.0451	0.1183
Onchocerca volvulus	DNA topoisomerase 2 homolog	0.0092	0.1939	0.5847
Echinococcus granulosus	transient receptor potential ion channel A	0.0092	0.1924	0.5218
Trichomonas vaginalis	DNA polymerase eta, putative	0.0059	0.1152	0.3651
Trypanosoma brucei	glucose transporter 1E	0.0032	0.0506	0.0752
Wolbachia endosymbiont of Brugia malayi	DNA gyrase, topoisomerase II, B subunit, GyrB	0.008	0.164	1
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.0909	0.2577
Trypanosoma brucei	mitochondrial DNA polymerase beta-PAK	0.014	0.3058	0.4543
Schistosoma mansoni	glucose transporter	0.0014	0.0097	0.0265
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0014	0.0097	0.0132
Echinococcus granulosus	solute carrier family 22	0.0014	0.0097	0.0214
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0018	0.0192	0.0286
Brugia malayi	ImpB/MucB/SamB family protein	0.0033	0.0538	0.1399
Echinococcus multilocularis	General substrate transporter	0.0088	0.1832	0.4964
Trypanosoma brucei	glucose transporter 2A	0.0032	0.0506	0.0752
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.014	0.3058	0.4543
Schistosoma mansoni	serine/threonine protein kinase	0.0031	0.0497	0.1354
Toxoplasma gondii	calcium-dependent protein kinase CDPK2A	0.0031	0.0497	0.0756
Brugia malayi	Cam kinase protein 1	0.0031	0.0497	0.1269
Entamoeba histolytica	hypothetical protein	0.0035	0.0589	0.0522
Loa Loa (eye worm)	hypothetical protein	0.0093	0.1942	0.5912
Mycobacterium ulcerans	sugar-transport integral membrane protein SugI	0.0014	0.0097	0.0283
Trypanosoma brucei	DNA polymerase kappa, putative	0.0036	0.0614	0.0912
Trypanosoma cruzi	hexose transporter, putative	0.0014	0.0097	0.0144
Toxoplasma gondii	exonuclease III APE	0.0018	0.0192	0.0292
Brugia malayi	exodeoxyribonuclease III family protein	0.0018	0.0192	0.0301
Trypanosoma cruzi	glucose transporter, putative	0.0014	0.0097	0.0144
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.0909	0.2577
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	0.0015	0.0123	0.0284
Trypanosoma brucei	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Brugia malayi	latrophilin 2 splice variant baaae	0.0033	0.0545	0.1421
Toxoplasma gondii	lysine-tRNA ligase	0.0023	0.0297	0.0451
Leishmania major	glucose transporter, lmgt3	0.0032	0.0506	0.0752
Trichomonas vaginalis	flap endonuclease-1, putative	0.0025	0.0359	0.0907
Trypanosoma brucei	DNA polymerase kappa, putative	0.0029	0.0448	0.0666
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0033	0.0538	0.1512
Brugia malayi	Latrophilin receptor protein 2	0.0015	0.0122	0.0079
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0102	0.2171	0.5894
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0734	0.2125
Entamoeba histolytica	hypothetical protein	0.0035	0.0589	0.0522
Brugia malayi	MH2 domain containing protein	0.0117	0.2515	0.7675
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0036	0.0602	0.0894
Trypanosoma cruzi	DNA topoisomerase II, putative	0.0129	0.2811	0.4176
Treponema pallidum	DNA gyrase, subunit A (gyrA)	0.0029	0.0452	0.2696
Trichomonas vaginalis	sugar transporter, putative	0.0032	0.0506	0.1416
Mycobacterium ulcerans	prolyl-tRNA synthetase	0.0011	0.0014	0.004
Trypanosoma brucei	DNA polymerase kappa, putative	0.0036	0.0614	0.0912
Schistosoma mansoni	hypothetical protein	0.0033	0.0545	0.1484
Trypanosoma brucei	myo-inositol/proton symporter (MIT)	0.0014	0.0097	0.0144
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0102	0.2171	0.5894
Trypanosoma brucei	sugar transporter, putative	0.0014	0.0097	0.0144
Trypanosoma brucei	DNA polymerase IV, putative	0.0059	0.1152	0.1711
Giardia lamblia	Hexose transporter	0.0014	0.0097	0.0125
Echinococcus multilocularis	expressed conserved protein	0.009	0.1893	0.5133
Trypanosoma brucei	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Mycobacterium ulcerans	DNA gyrase subunit A	0.0029	0.0452	0.1318
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0015	0.0122	0.0283
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0018	0.0192	0.0192
Trypanosoma brucei	DNA topoisomerase ii	0.0154	0.3381	0.5022
Echinococcus multilocularis	dna polymerase eta	0.0033	0.0538	0.1421
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0018	0.0192	0.056
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0042	0.0739	0.1097
Trypanosoma cruzi	hexose transporter, putative	0.0017	0.0167	0.0248
Trichomonas vaginalis	conserved hypothetical protein	0.0032	0.0506	0.1416
Trypanosoma brucei	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.0015	0.0123	0.0182
Trypanosoma cruzi	flap endonuclease-1 (FEN-1), putative	0.0025	0.0359	0.0534
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0122	0.021
Echinococcus multilocularis	protein patched	0.0041	0.0734	0.1957
Echinococcus multilocularis	dna polymerase kappa	0.0059	0.1152	0.3102
Leishmania major	hypothetical protein, conserved	0.0014	0.0097	0.0144
Trypanosoma cruzi	DNA polymerase eta, putative	0.0033	0.0538	0.0799
Trypanosoma brucei	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0015	0.0123	0.0284
Schistosoma mansoni	sugar transporter	0.0014	0.0097	0.0265
Toxoplasma gondii	flap structure-specific endonuclease 1, putative	0.0025	0.0359	0.0546
Leishmania major	mitochondrial DNA polymerase beta-PAK, putative	0.014	0.3058	0.4543
Trichomonas vaginalis	conserved hypothetical protein	0.0041	0.0734	0.2203
Toxoplasma gondii	LsmAD domain-containing protein	0.0025	0.034	0.0517
Trypanosoma brucei	DNA polymerase kappa, putative	0.004	0.069	0.1025
Entamoeba histolytica	hypothetical protein	0.0035	0.0589	0.0522
Echinococcus multilocularis	geminin	0.0166	0.3671	1
Chlamydia trachomatis	DNA gyrase subunit B	0.008	0.164	1
Chlamydia trachomatis	DNA gyrase subunit A	0.0029	0.0452	0.2696
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0296	0.6732	1
Echinococcus multilocularis	Niemann Pick C1 protein	0.0138	0.3007	0.8182
Entamoeba histolytica	Rad52/22 family double-strand break repair protein, putative	0.0097	0.2042	0.2436
Brugia malayi	Transient-receptor-potential like protein	0.0035	0.0592	0.1569
Plasmodium falciparum	calcium-dependent protein kinase 5	0.0031	0.0497	0.0497
Trypanosoma brucei	unspecified product	0.0023	0.0296	0.0439
Loa Loa (eye worm)	hypothetical protein	0.0093	0.1942	0.5912
Giardia lamblia	Lysyl-tRNA synthetase	0.0023	0.0297	0.0381
Giardia lamblia	DNA repair protein RAD52	0.034	0.7785	1
Mycobacterium ulcerans	sugar transporter	0.0014	0.0097	0.0283
Brugia malayi	Probable DNA topoisomerase II	0.0137	0.2985	0.9169
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0033	0.0538	0.1321
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Plasmodium vivax	calcium-dependent protein kinase 4, putative	0.0031	0.0497	0.0497
Trypanosoma brucei	DNA polymerase beta thumb, putative	0.0042	0.0739	0.1097
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0036	0.0602	0.0894
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0031	0.0482	0.1313
Echinococcus granulosus	GPCR family 2	0.0015	0.0122	0.0283
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Entamoeba histolytica	Niemann-Pick C1 protein, putative	0.0096	0.2031	0.2422
Trypanosoma brucei	unspecified product	0.0023	0.0296	0.0439
Plasmodium vivax	flap endonuclease 1, putative	0.0025	0.0359	0.0359
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0202	0.0459
Trypanosoma brucei	mitochondrial DNA polymerase beta	0.0296	0.6732	1
Schistosoma mansoni	lysyl-tRNA synthetase	0.0023	0.0297	0.0808
Brugia malayi	DNA topoisomerase II, alpha isozyme	0.0137	0.2985	0.9169
Loa Loa (eye worm)	MH2 domain-containing protein	0.0117	0.2515	0.7705
Echinococcus multilocularis	transient receptor potential ion channel A	0.0092	0.1924	0.5218
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0506	0.0752
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0031	0.0497	0.1309
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.0909	0.2675
Plasmodium falciparum	proline--tRNA ligase	0.0036	0.0602	0.0602
Toxoplasma gondii	isocitrate dehydrogenase	0.0015	0.0123	0.0187
Echinococcus multilocularis	Niemann Pick C1 protein	0.0096	0.2031	0.5511
Schistosoma mansoni	protein kinase	0.0031	0.0497	0.1354
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Brugia malayi	bifunctional aminoacyl-tRNA synthetase	0.0031	0.0482	0.1221
Plasmodium vivax	lysine--tRNA ligase, putative	0.0023	0.0297	0.0297
Loa Loa (eye worm)	hypothetical protein	0.0096	0.2031	0.6191
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0097	0.0132
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0517	0.1446
Echinococcus multilocularis	glutamyl tRNA synthetase cytoplasmic	0.0031	0.0482	0.1268
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0018	0.0192	0.0474
Mycobacterium ulcerans	hypothetical protein	0.0156	0.3431	1
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0202	0.0459
Loa Loa (eye worm)	abnormal chemotaxis protein 14	0.0041	0.0734	0.2125
Toxoplasma gondii	DNA topoisomerase 2, putative	0.0137	0.2985	0.454
Schistosoma mansoni	glucose transport protein	0.0102	0.2171	0.5915
Trypanosoma brucei	unspecified product	0.0053	0.0999	0.1485
Trichomonas vaginalis	DNA topoisomerase II, putative	0.0137	0.2985	1
Plasmodium vivax	DNA gyrase subunit A, putative	0.0029	0.0452	0.0452
Trypanosoma brucei	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0059	0.1152	0.1711
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0018	0.0192	0.0286
Schistosoma mansoni	sugar transporter	0.0014	0.0097	0.0265
Leishmania major	lysyl-tRNA synthetase, putative	0.0023	0.0297	0.0441
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0015	0.0122	0.0283
Schistosoma mansoni	ap endonuclease	0.0018	0.0192	0.0524
Echinococcus granulosus	General substrate transporter	0.0088	0.1832	0.4964
Plasmodium vivax	DNA topoisomerase II, putative	0.0137	0.2985	0.2985
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0497	0.1309
Plasmodium falciparum	calcium-dependent protein kinase 3	0.0031	0.0497	0.0497
Brugia malayi	hypothetical protein	0.0016	0.0134	0.0116
Brugia malayi	polk-prov protein	0.0036	0.0614	0.164
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0506	0.0752
Giardia lamblia	Sugar-proton symporter	0.0014	0.0097	0.0125
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.004	0.069	0.1025

Activities

Activity type	Activity value	Assay description	Source	Reference
Kcat (binding)	= 0.6 /s	Activity of recombinant human glutamate carboxypeptidase 2 expressed in Drosophila Schneider's S2 cells using NAAG as substrate after 30 mins by HPLC-based fluorometric analysis	ChEMBL.	21923190
Kcat/Km (binding)	= 75 L/mmol/s	Ratio of Kcat to Km recombinant human glutamate carboxypeptidase 2 expressed in Drosophila Schneider's S2 cells using NAAG as substrate after 30 mins by HPLC-based fluorometric analysis	ChEMBL.	21923190
Km (binding)	= 8 uM	Activity of recombinant human glutamate carboxypeptidase 2 expressed in Drosophila Schneider's S2 cells using NAAG as substrate after 30 mins by HPLC-based fluorometric analysis	ChEMBL.	21923190

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1927821

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 1565075