Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | glycogen synthase kinase 3 beta | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Protein kinase domain | 0.0084 | 0.027 | 0.027 |
Schistosoma mansoni | protein kinase | 0.0082 | 0.0246 | 0.0689 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.0246 | 0.9108 |
Echinococcus multilocularis | neural Wiskott Aldrich syndrome protein | 0.0082 | 0.0246 | 0.0271 |
Entamoeba histolytica | protein kinase, putative | 0.0084 | 0.027 | 1 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.006 | 0 | 0.5 |
Trichomonas vaginalis | STE family protein kinase | 0.0084 | 0.027 | 1 |
Echinococcus multilocularis | p21 activated protein kinase 1 Dpak1 | 0.0084 | 0.027 | 0.0297 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0084 | 0.027 | 0.0297 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 4 | 0.0877 | 0.909 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.0246 | 0.9108 |
Loa Loa (eye worm) | STE/STE20/PAKB protein kinase | 0.0959 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0084 | 0.027 | 1 |
Echinococcus granulosus | neural Wiskott Aldrich syndrome protein | 0.0082 | 0.0246 | 0.0271 |
Schistosoma mansoni | protein kinase | 0.0084 | 0.027 | 0.0756 |
Schistosoma mansoni | amine GPCR | 0.0381 | 0.3576 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 4 | 0.0877 | 0.909 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0084 | 0.027 | 1 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.0084 | 0.027 | 0.0297 |
Giardia lamblia | Kinase, STE STE20 | 0.0084 | 0.027 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0082 | 0.0246 | 0.0689 |
Trichomonas vaginalis | STE family protein kinase | 0.0084 | 0.027 | 1 |
Echinococcus granulosus | PAK box P21 Rho binding | 0.0082 | 0.0246 | 0.0271 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0246 | 0.0689 |
Onchocerca volvulus | 0.006 | 0 | 0.5 | |
Schistosoma mansoni | wiskott-aldrich syndrome protein | 0.0082 | 0.0246 | 0.0689 |
Entamoeba histolytica | protein kinase, putative | 0.0084 | 0.027 | 1 |
Schistosoma mansoni | protein kinase | 0.0084 | 0.027 | 0.0756 |
Echinococcus granulosus | 3'partial|serine:threonine protein kinase PAK 2 | 0.0082 | 0.0246 | 0.0271 |
Brugia malayi | WH1 domain containing protein | 0.0082 | 0.0246 | 0.0246 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.006 | 0 | 0.5 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.006 | 0 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0084 | 0.027 | 0.0297 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0084 | 0.027 | 0.0297 |
Brugia malayi | P21-Rho-binding domain containing protein | 0.0082 | 0.0246 | 0.0246 |
Trichomonas vaginalis | STE family protein kinase | 0.0084 | 0.027 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0084 | 0.027 | 0.0297 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.006 | 0 | 0.5 |
Entamoeba histolytica | p21-activated kinase | 0.0084 | 0.027 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0084 | 0.027 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.006 | 0 | 0.5 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.0082 | 0.0246 | 0.0271 |
Echinococcus granulosus | p21 activated protein kinase 1 Dpak1 | 0.0084 | 0.027 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0246 | 0.0246 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0246 | 0.0689 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0082 | 0.0246 | 0.0689 |
Brugia malayi | P21-Rho-binding domain containing protein | 0.0082 | 0.0246 | 0.0246 |
Entamoeba histolytica | protein kinase, putative | 0.0084 | 0.027 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0246 | 0.0689 |
Schistosoma mansoni | protein kinase | 0.0084 | 0.027 | 0.0756 |
Loa Loa (eye worm) | P21-Rho-binding domain-containing protein | 0.0082 | 0.0246 | 0.0246 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.006 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.0246 | 0.9108 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.