TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 192.258 | Formula: C11H16N2O
H donors: 1 H acceptors: 1 LogP: 1.24 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: OC(c1ccccc1)C/N=C/N(C)C
InChi: 1S/C11H16N2O/c1-13(2)9-12-8-11(14)10-6-4-3-5-7-10/h3-7,9,11,14H,8H2,1-2H3/b12-9+
InChiKey: QMJISUCYXPYHBZ-FMIVXFBMSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Giardia lamblia	Phosphoinositide-3-kinase, class 3	0.0471	0.051	0.0074
Entamoeba histolytica	FKBP-rapamycin associated protein (FRAP), putative	0.6441	1	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.6441	1	1
Entamoeba histolytica	protein kinase rad3, putative	0.1239	0.173	0.1649
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0493	0.0545	0.0506
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2203	0.3263	0.3263
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.057	0.0667	0.0667
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.2191	0.3244	0.2934
Echinococcus granulosus	phosphatidylinositol 45 bisphosphate 3 kinase	0.083	0.108	0.1065
Entamoeba histolytica	hypothetical protein	0.0427	0.0439	0.0346
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0449	0.0474	0.0474
Trichomonas vaginalis	PIKK family atypical protein kinase	0.418	0.6406	0.6406
Loa Loa (eye worm)	phosphatidylinositol 3	0.0786	0.101	0.0994
Loa Loa (eye worm)	hypothetical protein	0.1303	0.1832	0.1818
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3829	0.5849	0.5849
Trichomonas vaginalis	PIKK family atypical protein kinase	0.173	0.2511	0.2511
Echinococcus granulosus	phosphatidylinositol 4 kinase alpha	0.0449	0.0474	0.0458
Trichomonas vaginalis	PIKK family atypical protein kinase	0.5133	0.792	0.792
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0493	0.0545	0.0545
Echinococcus multilocularis	PIK kinase, FAT and Armadillo domain containing protein	0.0953	0.1275	0.126
Entamoeba histolytica	phosphatidylinositol-4,5-bisphosphate 3-kinase, putative	0.0449	0.0474	0.0381
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3499	0.5324	0.5324
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.1239	0.173	0.1716
Trypanosoma brucei	phosphatidylinositol 3-related kinase, putative	0.2203	0.3263	0.2953
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0449	0.0474	0.0474
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor2	0.6441	1	1
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0427	0.0439	0.5
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0493	0.0545	0.0529
Trichomonas vaginalis	conserved hypothetical protein	0.0812	0.1051	0.1051
Trichomonas vaginalis	PIKK family atypical protein kinase	0.4802	0.7395	0.7395
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3499	0.5324	0.5324
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0427	0.0439	0.0439
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.1239	0.173	0.135
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.1239	0.173	0.1716
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0427	0.0439	0.0439
Entamoeba histolytica	hypothetical protein	0.0427	0.0439	0.0346
Echinococcus granulosus	phosphatidylinositol 4 phosphate 3 kinase C2	0.0561	0.0653	0.0637
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit gamma, putative	0.0638	0.0775	0.0775
Echinococcus multilocularis	Phosphatidylinositol 4 kinase type 2 beta	0.0427	0.0439	0.0423
Trichomonas vaginalis	PIKK family atypical protein kinase	0.5133	0.792	0.792
Trypanosoma cruzi	phosphatidylinositol 4-kinase alpha, putative	0.0449	0.0474	0.0036
Trypanosoma brucei	phosphatidylinositol 3-kinase tor, putative	0.3038	0.459	0.4342
Echinococcus granulosus	phosphatidylinositol 3 kinase catalytic subunit	0.0449	0.0474	0.0458
Plasmodium vivax	phosphatidylinositol 3-kinase, putative	0.0449	0.0474	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.5488	0.8486	0.8486
Loa Loa (eye worm)	phosphatidylinositol 3	0.2203	0.3263	0.3251
Brugia malayi	phosphatidylinositol 4-kinase, catalytic, alpha polypeptide	0.0449	0.0474	0.0458
Echinococcus multilocularis	Zinc finger, PHD finger	0.0449	0.0474	0.0458
Trichomonas vaginalis	PIKK family atypical protein kinase	0.6441	1	1
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0638	0.0775	0.076
Leishmania major	target of rapamycin kinase (TOR) kinase 3	0.5138	0.7928	0.7833
Echinococcus multilocularis	phosphatidylinositol 4,5 bisphosphate 3 kinase	0.083	0.108	0.1065
Plasmodium falciparum	phosphatidylinositol 3-kinase	0.0449	0.0474	1
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0449	0.0474	0.005
Trichomonas vaginalis	conserved hypothetical protein	0.0953	0.1275	0.1275
Trichomonas vaginalis	PIKK family atypical protein kinase	0.385	0.5881	0.5881
Entamoeba histolytica	hypothetical protein	0.0594	0.0704	0.0614
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0812	0.1051	0.1051
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3494	0.5315	0.5315
Schistosoma mansoni	phosphatidylinositol 3-kinase class	0.0427	0.0439	0.04
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3829	0.5849	0.5849
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative	0.0493	0.0545	0.0545
Trichomonas vaginalis	PIKK family atypical protein kinase	0.4802	0.7395	0.7395
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0594	0.0704	0.0614
Echinococcus granulosus	FKBP12 rapamycin complex associated protein	0.6441	1	1
Trypanosoma brucei	phosphatidylinositol 4-kinase alpha, putative	0.0449	0.0474	0.0036
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3499	0.5324	0.5324
Echinococcus granulosus	DNA dependent protein kinase catalytic subunit	0.0712	0.0892	0.0877
Echinococcus multilocularis	serine:threonine protein kinase SMG1	0.1239	0.173	0.1716
Trichomonas vaginalis	PIKK family atypical protein kinase	0.5133	0.792	0.792
Schistosoma mansoni	phosphatidylinositol 4-kinase	0.0427	0.0439	0.04
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1239	0.173	0.173
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0493	0.0545	0.0545
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0638	0.0775	0.0775
Trichomonas vaginalis	phopsphatidylinositol 3-kinase, drosophila, putative	0.0427	0.0439	0.0439
Schistosoma mansoni	ataxia telangiectasia mutated (atm)	0.1239	0.173	0.1696
Loa Loa (eye worm)	hypothetical protein	0.0427	0.0439	0.0423
Echinococcus granulosus	phosphatidylinositol 3 and 4 kinase	0.2247	0.3333	0.3322
Brugia malayi	FAT domain containing protein	0.0953	0.1275	0.126
Leishmania major	phosphatidylinositol 3-kinase, putative	0.0449	0.0474	0.0036
Leishmania major	hypothetical protein, conserved	0.0528	0.06	0.0168
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0427	0.0439	0.0439
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.2247	0.3333	0.3027
Schistosoma mansoni	fkbp-rapamycin associated protein	0.1239	0.173	0.1696
Schistosoma mansoni	phosphatidylinositol 3-and 4-kinase	0.2247	0.3333	0.3306
Loa Loa (eye worm)	phosphatidylinositol 3	0.0427	0.0439	0.0423
Echinococcus granulosus	phosphatidylinositol 4 kinase beta	0.0427	0.0439	0.0423
Trypanosoma brucei	phosphatidylinositol kinase related protein, putative	0.1239	0.173	0.135
Trichomonas vaginalis	PIKK family atypical protein kinase	0.5133	0.792	0.792
Loa Loa (eye worm)	phosphatidylinositol 3	0.6441	1	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2191	0.3244	0.3244
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.6441	1	1
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0493	0.0545	0.0452
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0493	0.0545	0.0452
Echinococcus multilocularis	serine protein kinase ATM	0.1239	0.173	0.1716
Trichomonas vaginalis	PIKK family atypical protein kinase	0.385	0.5881	0.5881
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2191	0.3244	0.3244
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.2247	0.3333	0.3322
Echinococcus multilocularis	phosphatidylinositol 3 and 4 kinase	0.2247	0.3333	0.3322
Loa Loa (eye worm)	hypothetical protein	0.1379	0.1953	0.194
Leishmania major	target of rapamycin (TOR) kinase 2, putative	0.6441	1	1
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0517	0.0582	0.049
Onchocerca volvulus		0.0427	0.0439	0.5
Loa Loa (eye worm)	hypothetical protein	0.0561	0.0653	0.0637
Trichomonas vaginalis	conserved hypothetical protein	0.1379	0.1953	0.1953
Giardia lamblia	GTOR	0.6441	1	1
Trypanosoma cruzi	target of rapamycin kinase 3	0.5138	0.7928	0.7833
Trypanosoma cruzi	phosphatidylinositol 3-kinase 2, putative	0.0638	0.0775	0.0352
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.083	0.108	0.1044
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0427	0.0439	0.0423
Entamoeba histolytica	hypothetical protein	0.1239	0.173	0.1649
Trypanosoma cruzi	phosphatidylinositol 3-kinase 2, putative	0.0638	0.0775	0.0352
Trichomonas vaginalis	PIKK family atypical protein kinase	0.4802	0.7395	0.7395
Echinococcus multilocularis	Phosphatidylinositol 4 kinase type 2 beta	0.0427	0.0439	0.0423
Echinococcus granulosus	serine protein kinase ATM	0.1239	0.173	0.1716
Echinococcus multilocularis	phosphatidylinositol 4 kinase alpha	0.0449	0.0474	0.0458
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.2247	0.3333	0.3027
Echinococcus granulosus	Phosphatidylinositol 4 kinase type 2 beta	0.0427	0.0439	0.0423
Entamoeba histolytica	phosphatidylinositol3-kinaseTor2, putative	0.6441	1	1
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0449	0.0474	0.005
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0449	0.0474	0.0435
Leishmania major	phosphatidylinositol 4-kinase alpha, putative	0.0449	0.0474	0.0036
Toxoplasma gondii	target of rapamycin (TOR), putative	0.4802	0.7395	1
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0427	0.0439	0.0423
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3494	0.5315	0.5315
Trichomonas vaginalis	PIKK family atypical protein kinase	0.385	0.5881	0.5881
Entamoeba histolytica	phosphatidylinositol 3-kinase 3, putative	0.0427	0.0439	0.0346
Trichomonas vaginalis	PIKK family atypical protein kinase	0.4802	0.7395	0.7395
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1239	0.173	0.173
Trichomonas vaginalis	PIKK family atypical protein kinase	0.4802	0.7395	0.7395
Trichomonas vaginalis	PIKK family atypical protein kinase	0.4321	0.663	0.663
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.5138	0.7928	0.7833
Loa Loa (eye worm)	hypothetical protein	0.0953	0.1275	0.126
Trichomonas vaginalis	PIKK family atypical protein kinase	0.4802	0.7395	0.7395
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.6441	1	1
Echinococcus multilocularis	FKBP12 rapamycin complex associated protein	0.6441	1	1
Echinococcus granulosus	Phosphatidylinositol 4 kinase type 2 beta	0.0427	0.0439	0.0423
Trypanosoma cruzi	phosphatidylinositol 3-kinase vps34-like	0.0493	0.0545	0.011
Echinococcus multilocularis	phosphatidylinositol 4 phosphate 3 kinase C2	0.0561	0.0653	0.0637
Schistosoma mansoni	hypothetical protein	0.0427	0.0439	0.04
Trichomonas vaginalis	PIKK family atypical protein kinase	0.125	0.1749	0.1749
Loa Loa (eye worm)	phosphatidylinositol kinase	0.0427	0.0439	0.0423
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0638	0.0775	0.0685
Loa Loa (eye worm)	phosphatidylinositol 3	0.0427	0.0439	0.0423
Echinococcus granulosus	PIK kinase FAT and Armadillo domain containing protein	0.0953	0.1275	0.126
Toxoplasma gondii	non-specific serine/threonine protein kinase	0.1379	0.1953	0.2177
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor1	0.6441	1	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.5133	0.792	0.792
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3499	0.5324	0.5324
Brugia malayi	phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative	0.0192	0.0066	0.0049
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0812	0.1051	0.064
Loa Loa (eye worm)	phosphatidylinositol 3	0.0427	0.0439	0.0423
Echinococcus multilocularis		0.0427	0.0439	0.0423
Schistosoma mansoni	ataxia telangiectasia mutated (atm)-related	0.6441	1	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3494	0.5315	0.5315
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0427	0.0439	0.0423
Loa Loa (eye worm)	hypothetical protein	0.1239	0.173	0.1716
Leishmania major	phosphatidylinositol 3-related kinase, putative	0.2203	0.3263	0.2953
Toxoplasma gondii	FATC domain-containing protein	0.1239	0.173	0.1855
Loa Loa (eye worm)	phosphatidylinositol 3	0.0427	0.0439	0.0423
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2191	0.3244	0.3244
Trypanosoma cruzi	phosphatidylinositol 4-kinase alpha, putative	0.0449	0.0474	0.0036
Echinococcus multilocularis	DNA dependent protein kinase catalytic subunit	0.0712	0.0892	0.0877
Echinococcus granulosus	serine:threonine protein kinase SMG1	0.1239	0.173	0.1716
Trichomonas vaginalis	PIKK family atypical protein kinase	0.4802	0.7395	0.7395
Schistosoma mansoni	phosphatidylinositol 4-kinase	0.0449	0.0474	0.0435
Giardia lamblia	Phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.0525	0.0596	0.0164
Trichomonas vaginalis	phopsphatidylinositol 3-kinase, drosophila, putative	0.0638	0.0775	0.0775
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0561	0.0653	0.0637
Trypanosoma cruzi	phosphatidylinositol 3-kinase, putative	0.1239	0.173	0.135
Onchocerca volvulus		0.0427	0.0439	0.5
Mycobacterium leprae	conserved hypothetical protein	0.0427	0.0439	0.5
Trichomonas vaginalis	phosphatidylinositol 4-kinase, putative	0.0449	0.0474	0.0474
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2191	0.3244	0.3244
Leishmania major	target of rapamycin (TOR) kinase 1, putative	0.6441	1	1
Loa Loa (eye worm)	hypothetical protein	0.0812	0.1051	0.1036
Entamoeba histolytica	phosphatidylinositol 4-kinase, putative	0.0449	0.0474	0.0381
Trichomonas vaginalis	PIKK family atypical protein kinase	0.6441	1	1
Entamoeba histolytica	hypothetical protein	0.0427	0.0439	0.0346
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0493	0.0545	0.011
Leishmania major	phosphatidylinositol 3-kinase, putative	0.2191	0.3244	0.2934
Entamoeba histolytica	Phosphatidylinositol 3- and 4-kinase family	0.125	0.1749	0.1668
Schistosoma mansoni	hypothetical protein	0.0953	0.1275	0.124
Loa Loa (eye worm)	phosphatidylinositol 4-kinase type 3 alpha isoform 1	0.0449	0.0474	0.0458
Trypanosoma brucei	FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative	0.2688	0.4033	0.3759
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative	0.057	0.0667	0.0667
Schistosoma mansoni	phosphatidylinositol 4-kinase type-II	0.0427	0.0439	0.04

Activities

Activity type	Activity value	Assay description	Source	Reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory)	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2003135

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1647160