Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Dopamine receptor protein 2 | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | neuropeptide receptor | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0193 | 0.0446 | 0.0446 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein | 0.0081 | 0.0018 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.1659 | 0.6082 | 1 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0267 | 0.0733 | 0.1206 |
Schistosoma mansoni | neuropeptide receptor | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.011 | 0.0129 | 0.0212 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0456 | 0.1459 | 0.1459 |
Schistosoma mansoni | nAChR subunit | 0.0142 | 0.0251 | 0.0251 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0142 | 0.0251 | 0.1723 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.013 | 0.0207 | 0.0207 |
Echinococcus granulosus | fmrfamide receptor | 0.013 | 0.0207 | 0.0341 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0111 | 0.0133 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0456 | 0.1459 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.028 | 0.0781 | 0.5355 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0158 | 0.0313 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.1104 | 0.7569 |
Echinococcus granulosus | allatostatin A receptor | 0.013 | 0.0207 | 0.0341 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Loa Loa (eye worm) | neuropeptide F receptor | 0.013 | 0.0207 | 0.1422 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0086 | 0.0037 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.013 | 0.0207 | 0.1422 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Loa Loa (eye worm) | BEN-1 protein | 0.0158 | 0.0313 | 0.2144 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0097 | 0.0079 | 0.0131 |
Schistosoma mansoni | nAChR subunit | 0.0142 | 0.0251 | 0.0251 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0097 | 0.0079 | 0.0131 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0129 | 0.0129 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0142 | 0.0251 | 0.0413 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.011 | 0.0129 | 0.0883 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0097 | 0.0079 | 0.0544 |
Trypanosoma brucei | calpain-like protein, putative | 0.0111 | 0.0133 | 0.0294 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0097 | 0.0079 | 0.0131 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0097 | 0.0079 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0129 | 0.0883 |
Echinococcus multilocularis | neuropeptide s receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.013 | 0.0207 | 0.1422 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0079 | 0.0544 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | Cation transporter family protein | 0.0142 | 0.0251 | 0.1723 |
Echinococcus granulosus | neuropeptide receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | g protein coupled receptor | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.0781 | 0.5355 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0097 | 0.0079 | 0.0544 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0307 | 0.0885 | 0.0885 |
Brugia malayi | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Schistosoma mansoni | tubulin subunit beta | 0.0158 | 0.0313 | 0.0313 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0097 | 0.0079 | 0.0079 |
Echinococcus multilocularis | GPCR, family 2 | 0.011 | 0.0129 | 0.0212 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0097 | 0.0079 | 0.0544 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.013 | 0.0207 | 0.0207 |
Echinococcus multilocularis | sodium channel protein | 0.0197 | 0.0461 | 0.0759 |
Schistosoma mansoni | amine GPCR | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | opsin-like receptor | 0.013 | 0.0207 | 0.0207 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein (hisJ) | 0.0081 | 0.0018 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0097 | 0.0079 | 0.0544 |
Echinococcus granulosus | neuropeptides capa receptor | 0.013 | 0.0207 | 0.0341 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.028 | 0.0781 | 0.5355 |
Loa Loa (eye worm) | ACC-1 protein | 0.0142 | 0.0251 | 0.1723 |
Schistosoma mansoni | amine GPCR | 0.013 | 0.0207 | 0.0207 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.0384 | 0.1908 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0097 | 0.0079 | 0.0544 |
Schistosoma mansoni | serine-type protease inhibitor | 0.2679 | 1 | 1 |
Schistosoma mansoni | myosin xvIII | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | Serotonin receptor | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0142 | 0.0251 | 0.0413 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | tubulin, beta 4A class IVa | 0.0158 | 0.0313 | 0.0514 |
Echinococcus granulosus | neuropeptide Y receptor | 0.013 | 0.0207 | 0.0341 |
Mycobacterium ulcerans | hypothetical protein | 0.0332 | 0.098 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0097 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Echinococcus multilocularis | anti dorsalizing morphogenetic protein 1a | 0.0123 | 0.0179 | 0.0294 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | neuropeptide receptor | 0.013 | 0.0207 | 0.0341 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0097 | 0.0079 | 0.0544 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0142 | 0.0251 | 0.0251 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Brugia malayi | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | Integrin alpha cytoplasmic region family protein | 0.0112 | 0.0137 | 0.094 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0312 | 0.0903 | 0.0903 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0097 | 0.0079 | 0.0544 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0142 | 0.0251 | 0.0413 |
Onchocerca volvulus | 0.0456 | 0.1459 | 1 | |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0142 | 0.0251 | 0.1723 |
Brugia malayi | Latrophilin receptor protein 2 | 0.011 | 0.0129 | 0.0883 |
Echinococcus multilocularis | tubulin subunit beta | 0.0158 | 0.0313 | 0.0514 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | g-protein coupled receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | nAChR subunit | 0.0142 | 0.0251 | 0.0251 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0142 | 0.0251 | 0.0413 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0197 | 0.0461 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0193 | 0.0446 | 0.0734 |
Onchocerca volvulus | Putative nachr subunit | 0.0282 | 0.079 | 0.5413 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0142 | 0.0251 | 0.0413 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0097 | 0.0079 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.0358 | 0.0358 |
Brugia malayi | Cation transporter family protein | 0.0456 | 0.1459 | 1 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0364 | 0.1104 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.0349 | 0.0981 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Giardia lamblia | Beta tubulin | 0.0158 | 0.0313 | 0.5 |
Echinococcus granulosus | neuropeptide receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | beta tubulin | 0.0158 | 0.0313 | 0.0514 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0282 | 0.079 | 0.1298 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0123 | 0.0179 | 0.0295 |
Echinococcus multilocularis | allatostatin A receptor | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0282 | 0.079 | 0.1298 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0142 | 0.0251 | 0.1723 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0079 | 0.0544 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.0446 | 0.0446 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.0349 | 0.0981 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0332 | 0.098 | 1 |
Onchocerca volvulus | 0.0456 | 0.1459 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.0421 | 0.2884 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Trypanosoma brucei | beta tubulin | 0.0158 | 0.0313 | 0.209 |
Echinococcus multilocularis | sex peptide receptor | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0142 | 0.0251 | 0.0251 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.013 | 0.0207 | 0.0341 |
Giardia lamblia | Beta tubulin | 0.0158 | 0.0313 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.0349 | 0.0981 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.0349 | 0.0981 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0282 | 0.079 | 0.5413 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0142 | 0.0251 | 0.1723 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.0207 | 0.0207 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | tubulin beta-1 chain | 0.0158 | 0.0313 | 0.2144 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0142 | 0.0251 | 0.1723 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0142 | 0.0251 | 0.1723 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0142 | 0.0251 | 0.1723 |
Onchocerca volvulus | 0.0097 | 0.0079 | 0.0544 | |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0142 | 0.0251 | 0.0413 |
Echinococcus granulosus | nAChR subunit | 0.0142 | 0.0251 | 0.0413 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0167 | 0.0349 | 0.2396 |
Schistosoma mansoni | thyroid hormone receptor | 0.0097 | 0.0079 | 0.0079 |
Plasmodium falciparum | tubulin beta chain | 0.0158 | 0.0313 | 0.5 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Schistosoma mansoni | hypothetical protein | 0.0103 | 0.0104 | 0.0104 |
Schistosoma mansoni | tubulin subunit beta | 0.0158 | 0.0313 | 0.0313 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.013 | 0.0207 | 0.1422 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Echinococcus granulosus | hypothetical protein | 0.013 | 0.0207 | 0.0341 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.017 | 0.0358 | 0.2457 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.1488 | 0.5423 | 0.8916 |
Brugia malayi | G protein-coupled receptor | 0.013 | 0.0207 | 0.1422 |
Trypanosoma brucei | calpain, putative | 0.0111 | 0.0133 | 0.0294 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0142 | 0.0251 | 0.1723 |
Schistosoma mansoni | biogenic amine receptor | 0.013 | 0.0207 | 0.0207 |
Brugia malayi | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0079 | 0.0544 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0113 | 0.014 | 0.023 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0456 | 0.1459 | 0.1459 |
Brugia malayi | beta-tubulin, identical | 0.0158 | 0.0313 | 0.2144 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.011 | 0.0129 | 0.0212 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0097 | 0.0079 | 0.0079 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0197 | 0.0461 | 0.3381 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0158 | 0.0313 | 0.0514 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0255 | 0.0687 | 0.4707 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0079 | 0.0544 |
Brugia malayi | ORL1-like opioid receptor | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.011 | 0.0129 | 0.0212 |
Loa Loa (eye worm) | ACC-1 protein | 0.0142 | 0.0251 | 0.1723 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.013 | 0.0207 | 0.0207 |
Trypanosoma brucei | hypothetical protein | 0.0111 | 0.0133 | 0.0294 |
Brugia malayi | Serotonin receptor | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0129 | 0.0129 |
Schistosoma mansoni | integrin alpha | 0.0148 | 0.0276 | 0.0276 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.0111 | 0.0133 | 0.0294 |
Echinococcus multilocularis | fmrfamide receptor | 0.013 | 0.0207 | 0.0341 |
Brugia malayi | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.1488 | 0.5423 | 0.8916 |
Schistosoma mansoni | nAChR subunit | 0.0142 | 0.0251 | 0.0251 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | nuclear hormone receptor | 0.0097 | 0.0079 | 0.0079 |
Toxoplasma gondii | PAN domain-containing protein | 0.0921 | 0.3243 | 1 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0097 | 0.0079 | 0.0544 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.013 | 0.0207 | 0.1422 |
Trypanosoma brucei | beta tubulin | 0.0158 | 0.0313 | 0.209 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | g protein coupled receptor | 0.013 | 0.0207 | 0.0341 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.0687 | 1 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | protein kinase | 0.0123 | 0.0179 | 0.0179 |
Echinococcus granulosus | neuropeptide Y receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0282 | 0.079 | 0.1298 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Mycobacterium tuberculosis | Conserved protein | 0.0332 | 0.098 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0097 | 0.0079 | 0.0079 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0332 | 0.098 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Brugia malayi | G-protein coupled receptor | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.0446 | 0.0446 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | beta tubulin | 0.0158 | 0.0313 | 0.0514 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type | 0.0123 | 0.0179 | 0.0295 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.0687 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0097 | 0.0079 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.011 | 0.0129 | 0.0212 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0097 | 0.0079 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0391 | 0.1207 | 0.8277 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0097 | 0.0079 | 0.0131 |
Schistosoma mansoni | protein kinase | 0.0123 | 0.0179 | 0.0179 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0111 | 0.0133 | 0.0294 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0142 | 0.0251 | 0.0413 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.013 | 0.0207 | 0.0207 |
Echinococcus granulosus | integrin alpha 3 | 0.0114 | 0.0143 | 0.0235 |
Brugia malayi | Angiotensin-converting enzyme family protein | 0.0158 | 0.0313 | 0.2148 |
Chlamydia trachomatis | glutamine binding protein | 0.0081 | 0.0018 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0129 | 0.0129 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Mycobacterium leprae | conserved hypothetical protein | 0.0332 | 0.098 | 0.5 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0193 | 0.0446 | 0.0734 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0097 | 0.0079 | 0.0079 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.013 | 0.0207 | 0.0207 |
Onchocerca volvulus | 0.0256 | 0.0688 | 0.472 | |
Onchocerca volvulus | 0.0307 | 0.0885 | 0.6068 | |
Schistosoma mansoni | coup transcription factor | 0.0097 | 0.0079 | 0.0079 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0142 | 0.0251 | 0.0413 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0142 | 0.0251 | 0.0413 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.013 | 0.0207 | 0.0341 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.0349 | 0.0981 |
Schistosoma mansoni | amine GPCR | 0.013 | 0.0207 | 0.0207 |
Brugia malayi | neuropeptide F receptor | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0142 | 0.0251 | 0.1723 |
Brugia malayi | Tubulin beta-1 chain | 0.0158 | 0.0313 | 0.2144 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0097 | 0.0079 | 0.0131 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0142 | 0.0251 | 0.1723 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | nAChR subunit | 0.0142 | 0.0251 | 0.0251 |
Schistosoma mansoni | nAChR subunit | 0.0142 | 0.0251 | 0.0251 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.002 | 0.014 |
Schistosoma mansoni | protein kinase | 0.0123 | 0.0179 | 0.0179 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.0446 | 0.0446 |
Loa Loa (eye worm) | calcium/calmodulin-dependent protein kinase subunit type II alpha | 0.0108 | 0.012 | 0.0824 |
Brugia malayi | bZIP transcription factor family protein | 0.0086 | 0.0037 | 0.0253 |
Echinococcus multilocularis | jun protein | 0.0086 | 0.0037 | 0.0061 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0142 | 0.0251 | 0.0413 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.013 | 0.0207 | 0.0341 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0097 | 0.0079 | 0.0544 |
Toxoplasma gondii | PAN domain-containing protein | 0.0921 | 0.3243 | 1 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.013 | 0.0207 | 0.0207 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0097 | 0.0079 | 0.0544 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0158 | 0.0313 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0079 | 0.0544 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0142 | 0.0251 | 0.1723 |
Entamoeba histolytica | tubulin family protein | 0.0158 | 0.0313 | 0.3191 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | tubulin beta chain | 0.0158 | 0.0313 | 0.2144 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0086 | 0.0037 | 0.0061 |
Trypanosoma brucei | beta tubulin | 0.0158 | 0.0313 | 0.209 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.0687 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0255 | 0.0687 | 0.4707 |
Schistosoma mansoni | histamine h1 receptor | 0.013 | 0.0207 | 0.0207 |
Echinococcus granulosus | sodium channel protein | 0.0197 | 0.0461 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0097 | 0.0079 | 0.0131 |
Echinococcus granulosus | somatostatin receptor | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | tubulin subunit beta | 0.0158 | 0.0313 | 0.0313 |
Echinococcus granulosus | GPCR family 2 | 0.011 | 0.0129 | 0.0212 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Onchocerca volvulus | 0.0142 | 0.0251 | 0.1723 | |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.0207 | 0.0207 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0097 | 0.0079 | 0.0544 |
Brugia malayi | Calcium/calmodulin-dependent protein kinase type II alpha chain | 0.0108 | 0.012 | 0.0824 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Brugia malayi | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | nuclear hormone receptor | 0.0097 | 0.0079 | 0.0544 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0097 | 0.0079 | 0.0544 |
Echinococcus multilocularis | integrin alpha 3 | 0.0114 | 0.0143 | 0.0235 |
Brugia malayi | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.0307 | 0.0885 | 0.6068 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.1659 | 0.6082 | 1 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0142 | 0.0251 | 0.0413 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Chlamydia trachomatis | arginine ABC transporter substrate-binding protein ArtJ | 0.0081 | 0.0018 | 0.5 |
Loa Loa (eye worm) | integrin alpha pat-2 | 0.0229 | 0.0585 | 0.4007 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0267 | 0.0733 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0282 | 0.079 | 0.1298 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Schistosoma mansoni | apoptosis regulator bax | 0.0193 | 0.0446 | 0.0446 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013 | 0.0207 | 0.0207 |
Echinococcus multilocularis | serotonin receptor | 0.013 | 0.0207 | 0.0341 |
Onchocerca volvulus | 0.0456 | 0.1459 | 1 | |
Brugia malayi | Transforming growth factor beta like domain containing protein | 0.0123 | 0.0179 | 0.1227 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0158 | 0.0313 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0137 | 0.094 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0097 | 0.0079 | 0.0544 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.013 | 0.0207 | 0.0207 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | serotonin receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | neuropeptide s receptor | 0.013 | 0.0207 | 0.0341 |
Brugia malayi | Dopamine receptor | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0142 | 0.0251 | 0.1723 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0097 | 0.0079 | 0.0544 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0097 | 0.0079 | 0.0544 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0142 | 0.0251 | 0.0413 |
Schistosoma mansoni | neuropeptide receptor | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Brugia malayi | ecdysteroid receptor | 0.0097 | 0.0079 | 0.0544 |
Echinococcus multilocularis | beta tubulin | 0.0158 | 0.0313 | 0.0514 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0142 | 0.0251 | 0.1723 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0097 | 0.0079 | 0.0544 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0267 | 0.0733 | 0.1206 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0142 | 0.0251 | 0.1723 |
Brugia malayi | steroid hormone receptor | 0.0097 | 0.0079 | 0.0544 |
Echinococcus granulosus | orexin receptor type 2 | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | tubulin beta 1 chain | 0.0158 | 0.0313 | 0.0514 |
Echinococcus multilocularis | orexin receptor type 2 | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0111 | 0.0133 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | tubulin subunit beta | 0.0158 | 0.0313 | 0.0313 |
Loa Loa (eye worm) | BEN-1 protein | 0.0158 | 0.0313 | 0.2144 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Echinococcus granulosus | tubulin beta 4A class IVa | 0.0158 | 0.0313 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0111 | 0.0133 | 0.0294 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0097 | 0.0079 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0153 | 0.1052 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0158 | 0.0313 | 0.0514 |
Echinococcus multilocularis | somatostatin receptor | 0.013 | 0.0207 | 0.0341 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Brugia malayi | G-protein coupled receptor | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.0349 | 0.0981 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0097 | 0.0079 | 0.0131 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0282 | 0.079 | 0.5413 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.013 | 0.0207 | 0.0341 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0142 | 0.0251 | 0.1723 |
Brugia malayi | GnHR receptor homolog | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0097 | 0.0079 | 0.0544 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | LGC-31 protein | 0.0142 | 0.0251 | 0.1723 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0097 | 0.0079 | 0.0544 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.011 | 0.0129 | 0.0883 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0142 | 0.0251 | 0.0413 |
Echinococcus granulosus | g protein coupled receptor | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013 | 0.0207 | 0.0207 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0364 | 0.1104 | 1 |
Brugia malayi | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Onchocerca volvulus | 0.0142 | 0.0251 | 0.1723 | |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0097 | 0.0079 | 0.0131 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.0446 | 0.3059 |
Brugia malayi | Dopamine receptor protein 1 | 0.013 | 0.0207 | 0.1422 |
Echinococcus granulosus | beta tubulin | 0.0158 | 0.0313 | 0.0514 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0079 | 0.0544 |
Loa Loa (eye worm) | bone morphogenic protein 6 | 0.0123 | 0.0179 | 0.1227 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0142 | 0.0251 | 0.0413 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0142 | 0.0251 | 0.0413 |
Trypanosoma cruzi | beta tubulin, putative | 0.0158 | 0.0313 | 0.1851 |
Schistosoma mansoni | adenoreceptor | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | amine GPCR | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.013 | 0.0207 | 0.0207 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0364 | 0.1104 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0113 | 0.014 | 0.023 |
Brugia malayi | putative neuropeptide receptor | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0097 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0142 | 0.0251 | 0.1723 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0142 | 0.0251 | 0.0413 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0142 | 0.0251 | 0.1723 |
Trypanosoma brucei | beta tubulin | 0.0158 | 0.0313 | 0.209 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0097 | 0.0079 | 0.0131 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0282 | 0.079 | 0.1298 |
Echinococcus granulosus | tubulin subunit beta | 0.0158 | 0.0313 | 0.0514 |
Schistosoma mansoni | tubulin subunit beta | 0.0158 | 0.0313 | 0.0313 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0282 | 0.079 | 0.1298 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.0687 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | tubulin beta-4 chain | 0.0158 | 0.0313 | 0.2144 |
Brugia malayi | Melatonin receptor type 1A | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.0384 | 0.1908 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.0687 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0097 | 0.0079 | 0.0544 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Onchocerca volvulus | 0.0142 | 0.0251 | 0.1723 | |
Echinococcus multilocularis | fmrfamide receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | serotonin receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.013 | 0.0207 | 0.0341 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.0349 | 0.0981 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Echinococcus granulosus | FTZ F1 alpha | 0.0097 | 0.0079 | 0.0131 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013 | 0.0207 | 0.0207 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0113 | 0.014 | 0.023 |
Brugia malayi | AKH receptor | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | biogenic amine receptor | 0.013 | 0.0207 | 0.0207 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | g protein coupled receptor | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0097 | 0.0079 | 0.0079 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.013 | 0.0207 | 0.1422 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0142 | 0.0251 | 0.0413 |
Brugia malayi | RE15519p | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0142 | 0.0251 | 0.1723 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.013 | 0.0207 | 0.0207 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Schistosoma mansoni | neuropeptide receptor | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | beta-tubulin | 0.0158 | 0.0313 | 0.2144 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0142 | 0.0251 | 0.1723 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0097 | 0.0079 | 0.0544 |
Echinococcus multilocularis | g-protein coupled receptor | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0079 | 0.0544 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0097 | 0.0079 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0251 | 0.1723 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0142 | 0.0251 | 0.0413 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.013 | 0.0207 | 0.0341 |
Brugia malayi | Trypsin family protein | 0.0307 | 0.0885 | 0.6068 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0097 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | TYRA-2 protein | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | opsin-like receptor | 0.013 | 0.0207 | 0.0207 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0142 | 0.0251 | 0.1723 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.0158 | 0.0313 | 0.2148 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | opsin-like receptor | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013 | 0.0207 | 0.0207 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.013 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0307 | 0.0885 | 0.6068 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.013 | 0.0207 | 0.0341 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0097 | 0.0079 | 0.0544 |
Giardia lamblia | Beta tubulin | 0.0158 | 0.0313 | 0.5 |
Brugia malayi | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0097 | 0.0079 | 0.0544 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0142 | 0.0251 | 0.0413 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0028 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.013 | 0.0207 | 0.0207 |
Leishmania major | beta tubulin | 0.0158 | 0.0313 | 0.1851 |
Schistosoma mansoni | amine GPCR | 0.013 | 0.0207 | 0.0207 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0142 | 0.0251 | 0.1723 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0158 | 0.0313 | 0.0514 |
Brugia malayi | sulfakinin receptor protein | 0.013 | 0.0207 | 0.1422 |
Trypanosoma brucei | variant surface glycoprotein (VSG), putative | 0.0111 | 0.0133 | 0.0294 |
Echinococcus granulosus | sex peptide receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | g protein coupled receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | nAChR subunit | 0.0142 | 0.0251 | 0.0413 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0097 | 0.0079 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0456 | 0.1459 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0097 | 0.0079 | 0.0544 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013 | 0.0207 | 0.0341 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0158 | 0.0313 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.013 | 0.0207 | 0.1422 |
Schistosoma mansoni | biogenic amine receptor | 0.013 | 0.0207 | 0.0207 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0097 | 0.0079 | 0.0544 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0158 | 0.0313 | 0.0514 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Brugia malayi | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | nuclear receptor NHR-88 | 0.0097 | 0.0079 | 0.0544 |
Entamoeba histolytica | tubulin family protein | 0.0158 | 0.0313 | 0.3191 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0097 | 0.0079 | 0.0131 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.013 | 0.0207 | 0.0341 |
Schistosoma mansoni | nAChR subunit | 0.0142 | 0.0251 | 0.0251 |
Schistosoma mansoni | tubulin subunit beta | 0.0158 | 0.0313 | 0.0313 |
Echinococcus granulosus | jun protein | 0.0086 | 0.0037 | 0.0061 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0142 | 0.0251 | 0.0251 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0111 | 0.0133 | 0.0294 |
Schistosoma mansoni | thyroid hormone receptor | 0.0097 | 0.0079 | 0.0079 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0097 | 0.0079 | 0.0131 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0364 | 0.1104 | 0.7569 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0097 | 0.0079 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0079 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.079 | 0.5413 |
Echinococcus granulosus | g protein coupled receptor | 0.013 | 0.0207 | 0.0341 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.013 | 0.0207 | 0.1422 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.013 | 0.0207 | 0.1422 |
Echinococcus multilocularis | neuropeptide receptor | 0.013 | 0.0207 | 0.0341 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0158 | 0.0313 | 0.0514 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0142 | 0.0251 | 0.0251 |
Brugia malayi | Integrin alpha pat-2 precursor | 0.0148 | 0.0276 | 0.1892 |
Echinococcus granulosus | anti dorsalizing morphogenetic protein 1a | 0.0123 | 0.0179 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.0358 | 0.2457 |
Brugia malayi | follicle stimulating hormone receptor | 0.013 | 0.0207 | 0.1422 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0097 | 0.0079 | 0.0131 |
Echinococcus multilocularis | tubulin beta 1 chain | 0.0158 | 0.0313 | 0.0514 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0193 | 0.0446 | 0.3059 |
Mycobacterium ulcerans | hypothetical protein | 0.0332 | 0.098 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013 | 0.0207 | 0.0207 |
Brugia malayi | neuropeptide F receptor | 0.013 | 0.0207 | 0.1422 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.0687 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Plasmodium vivax | tubulin beta chain, putative | 0.0158 | 0.0313 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | tubulin beta-2A chain | 0.0158 | 0.0313 | 0.2144 |
Brugia malayi | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.028 | 0.0781 | 0.5355 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | larval opioid receptor | 0.013 | 0.0207 | 0.1422 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0158 | 0.0313 | 0.0514 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0097 | 0.0079 | 0.0131 |
Onchocerca volvulus | 0.013 | 0.0207 | 0.1422 | |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0207 | 0.1422 |
Brugia malayi | Cation transporter family protein | 0.0142 | 0.0251 | 0.1723 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.013 | 0.0207 | 0.0207 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0193 | 0.0446 | 0.3059 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
AUC (ADMET) | = 328 ug min ml-1 | AUC in dog after oral dose (1 mg/kg) | ChEMBL. | 12270176 |
Cmax (ADMET) | = 1.52 ug ml-1 | Cmax in dog plasma after oral dose (1 mg/kg) | ChEMBL. | 12270176 |
Ki (binding) | = 22.2 ug nM-1 | In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrate | ChEMBL. | 12270176 |
Ki (binding) | = 22.2 ug nM-1 | In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrate | ChEMBL. | 12270176 |
pKa | = 8.6 | Ionisation constant (pKa) | ChEMBL. | 12270176 |
T1/2 (ADMET) | = 109 min | t1/2 in dog after oral dose (1 mg/kg) | ChEMBL. | 12270176 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.