Detailed information for compound 1689911

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 390.415 | Formula: C16H31N4O5P
  • H donors: 4 H acceptors: 3 LogP: -0.41 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOP(=O)(C1=C[C@H]([C@@H]([C@H](C1)NC(=N)N)NC(=O)C)OC(CC)CC)O
  • InChi: 1S/C16H31N4O5P/c1-5-11(6-2)25-14-9-12(26(22,23)24-7-3)8-13(20-16(17)18)15(14)19-10(4)21/h9,11,13-15H,5-8H2,1-4H3,(H,19,21)(H,22,23)(H4,17,18,20)/t13-,14+,15+/m0/s1
  • InChiKey: FRYSRHHJWNBUDF-RRFJBIMHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus(strain A/WS/1933 H1N1)) Neuraminidase Starlite/ChEMBL References
Influenza A virus Neuraminidase Starlite/ChEMBL References
Influenza A virus Neuraminidase Starlite/ChEMBL References
Influenza A virus Neuraminidase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium knowlesi ubiquitin-conjugating enzyme E2 N, putative Get druggable targets OG5_127739 All targets in OG5_127739
Candida albicans 3' exon of potential Low molecular weight phosphoTyrosine Phosphatase gene Get druggable targets OG5_127571 All targets in OG5_127571
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Leishmania donovani ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Cryptosporidium parvum ubiquitin-conjugating enzyme Get druggable targets OG5_127739 All targets in OG5_127739
Echinococcus granulosus ubiquitin conjugating enzyme E2 N Get druggable targets OG5_127739 All targets in OG5_127739
Brugia malayi Ubiquitin conjugating enzyme protein 13 Get druggable targets OG5_127739 All targets in OG5_127739
Loa Loa (eye worm) phosphotyrosine protein phosphatase Get druggable targets OG5_127571 All targets in OG5_127571
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein Get druggable targets OG5_127571 All targets in OG5_127571
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 Get druggable targets OG5_127739 All targets in OG5_127739
Neospora caninum Ubiquitin carrier protein (EC 6.3.2.-), related Get druggable targets OG5_127739 All targets in OG5_127739
Trypanosoma brucei ubiquitin-protein ligase, putative Get druggable targets OG5_127739 All targets in OG5_127739
Schistosoma mansoni ubiquitin conjugating enzyme 13 Get druggable targets OG5_127739 All targets in OG5_127739
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative Get druggable targets OG5_127571 All targets in OG5_127571
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Candida albicans ubiquitin-conjugating enzyme Get druggable targets OG5_127739 All targets in OG5_127739
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Trypanosoma brucei gambiense ubiquitin-conjugating enzyme e2, putative,ubiquitin carrier protein, putative,ubiquitin-protein ligase, putative Get druggable targets OG5_127739 All targets in OG5_127739
Entamoeba histolytica protein tyrosine phosphatase, putative Get druggable targets OG5_127571 All targets in OG5_127571
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative Get druggable targets OG5_127739 All targets in OG5_127739
Trypanosoma congolense ubiquitin-protein ligase, putative Get druggable targets OG5_127739 All targets in OG5_127739
Leishmania major ubiquitin-conjugating enzyme e2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Leishmania infantum ubiquitin-conjugating enzyme e2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 Get druggable targets OG5_127739 All targets in OG5_127739
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase Get druggable targets OG5_127571 All targets in OG5_127571
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative Get druggable targets OG5_127571 All targets in OG5_127571
Entamoeba histolytica protein tyrosine phosphatase, putative Get druggable targets OG5_127571 All targets in OG5_127571
Brugia malayi ubiquitin conjugating enzyme protein 13 Get druggable targets OG5_127739 All targets in OG5_127739
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein Get druggable targets OG5_127739 All targets in OG5_127739
Candida albicans post-replication repair Get druggable targets OG5_127739 All targets in OG5_127739
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative Get druggable targets OG5_127571 All targets in OG5_127571
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) Get druggable targets OG5_127571 All targets in OG5_127571
Leishmania mexicana ubiquitin-conjugating enzyme e2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Plasmodium berghei ubiquitin-conjugating enzyme E2 N, putative Get druggable targets OG5_127739 All targets in OG5_127739
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative Get druggable targets OG5_127571 All targets in OG5_127571
Candida albicans ubiquitin conjugating enzyme Get druggable targets OG5_127739 All targets in OG5_127739
Babesia bovis ubiquitin-conjugating enzyme E2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Cryptosporidium hominis ubiquitin-conjugating enzyme Get druggable targets OG5_127739 All targets in OG5_127739
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative Get druggable targets OG5_127739 All targets in OG5_127739
Entamoeba histolytica ubiquitin-conjugating enzyme family protein Get druggable targets OG5_127739 All targets in OG5_127739
Leishmania braziliensis ubiquitin-conjugating enzyme e2, putative Get druggable targets OG5_127739 All targets in OG5_127739
Candida albicans C terminus of potential Low molecular weight phosphoTyrosine Phosphatase Get druggable targets OG5_127571 All targets in OG5_127571
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA Get druggable targets OG5_127571 All targets in OG5_127571
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative Get druggable targets OG5_127571 All targets in OG5_127571
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative Get druggable targets OG5_127571 All targets in OG5_127571
Onchocerca volvulus Get druggable targets OG5_127571 All targets in OG5_127571
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N Get druggable targets OG5_127739 All targets in OG5_127739
Theileria parva ubiquitin-protein ligase, putative Get druggable targets OG5_127739 All targets in OG5_127739
Schistosoma japonicum ko:K10580 ubiquitin-conjugating enzyme E2 N, putative Get druggable targets OG5_127739 All targets in OG5_127739
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0046 0.2675 1
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0062 0.0062
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0886 0.1149
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0694 0.0694
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0694 0.0694
Loa Loa (eye worm) hypothetical protein 0.0023 0.1144 0.1088
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0156 1 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.3546 0.4862
Onchocerca volvulus 0.0028 0.1467 0.1414
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.1144 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.1144 0.1088
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0757 0.2658
Mycobacterium ulcerans hypothetical protein 0.0023 0.1144 0.1088
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0156 1 1
Brugia malayi AMP-binding enzyme family protein 0.0023 0.1144 0.1088
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0046 0.2675 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.1144 0.1088
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0886 0.3152
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0074 0.0016
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.1144 0.1088
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0757 0.0757
Brugia malayi CXXC zinc finger family protein 0.0028 0.1467 0.1414
Schistosoma mansoni lipoxygenase 0.008 0.4937 0.6802
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0156 1 1
Schistosoma mansoni cpg binding protein 0.0029 0.1573 0.2108
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.1144 0.4139
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0046 0.2675 0.8528
Echinococcus multilocularis cpg binding protein 0.0029 0.1573 0.2108
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0046 0.2675 1
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0062 0.0062
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0156 1 1
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0156 1 0.5
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.1144 0.4139
Loa Loa (eye worm) hypothetical protein 0.0017 0.0757 0.0699
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.1144 0.1088
Onchocerca volvulus 0.0019 0.0886 0.0829
Brugia malayi AMP-binding enzyme family protein 0.0023 0.1144 0.1088
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0156 1 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0074 0.0016
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0046 0.2675 0.3646
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.1144 0.1088
Loa Loa (eye worm) hypothetical protein 0.0017 0.0757 0.0699
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.1144 0.1088
Loa Loa (eye worm) hypothetical protein 0.0023 0.1144 0.1088
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.1144 0.1088
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0062 0.0062
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0062 0.0062
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0046 0.2675 0.3646
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0156 1 1
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0046 0.2675 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.3126 1
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0156 1 1
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0017 0.0757 0.0699
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0074 0.0016
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0062 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.1144 0.1144
Schistosoma mansoni lipoxygenase 0.0115 0.7229 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.1144 0.1088
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0886 0.3152
Schistosoma mansoni cpg binding protein 0.0028 0.1467 0.1961
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0886 0.1149
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0179 0.0118
Brugia malayi hypothetical protein 0.0019 0.0886 0.0829
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0046 0.2675 0.3646
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0757 0.0699
Brugia malayi hypothetical protein 0.0019 0.0886 0.0829
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0046 0.2675 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0115 0.7229 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0156 1 1
Echinococcus multilocularis RUN 0.0019 0.0886 0.1149
Brugia malayi AMP-binding enzyme family protein 0.0023 0.1144 0.1088
Schistosoma mansoni polycystin 1-related 0.0019 0.0886 0.1149
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0046 0.2675 1
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0062 0.0062
Brugia malayi Doublecortin family protein 0.0019 0.0886 0.0829
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0156 1 1
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0046 0.2675 0.2629
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0886 0.0829
Schistosoma mansoni hypothetical protein 0.0019 0.0886 0.1149
Echinococcus granulosus cpg binding protein 0.0029 0.1573 0.2108
Loa Loa (eye worm) hypothetical protein 0.0019 0.0886 0.0829
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0046 0.2675 0.2629
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0156 1 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0156 1 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0187 0.0173
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0757 0.2658
Echinococcus granulosus RUN 0.0019 0.0886 0.1149
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0187 0.0125
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0074 0.0016
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0046 0.2675 0.2629
Schistosoma mansoni rab6-interacting 0.0019 0.0886 0.1149
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.1144 0.1088
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0062 0.0062
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0187 0.0173
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0062 0.0062
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.1144 0.4139
Loa Loa (eye worm) hypothetical protein 0.0017 0.0757 0.0699
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0886 0.1149
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0886 0.1149
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0062 0.0029
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.1144 0.1144
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0886 0.1149
Loa Loa (eye worm) hypothetical protein 0.0017 0.0757 0.0699
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0062 0.0062
Onchocerca volvulus 0.0023 0.1144 0.1088
Onchocerca volvulus 0.0019 0.0886 0.0829
Schistosoma mansoni loxhd1 0.0019 0.0886 0.1149
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0115 0.7229 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0886 0.0829
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.1467 0.1414
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0046 0.2675 0.2629
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0062 0.0062
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0046 0.2675 0.2651
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0886 0.1149
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.1144 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0074 0.0016
Onchocerca volvulus 0.0156 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0694 0.0694
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0046 0.2675 0.2629
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0046 0.2675 0.2651
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0694 0.0694
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.1144 0.1088
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0757 0.5
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0062 0.0062
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.1144 0.1088
Schistosoma mansoni cpg binding protein 0.0029 0.1573 0.2108
Schistosoma mansoni rab6-interacting 0.0019 0.0886 0.1149

Activities

Activity type Activity value Assay description Source Reference
Fu (ADMET) = 86 % Fraction unbound in human plasma at 1 uM after 4 hrs ChEMBL. 23009169
IC50 (binding) = 1.1 nM Inhibition of wild type Influenza A virus A/WSN/1933(H1N1) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid as substrate incubated for 10 mins prior to substrate addition by fluorescence assay ChEMBL. 23009169
IC50 (binding) = 17.4 nM Inhibition of Influenza A virus (A/reassortant/NIBRG-14(Viet Nam/1194/2004 x Puerto Rico/8/1934)(H5N1)) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid as substrate incubated for 10 mins prior to substrate addition by fluorescence assay ChEMBL. 23009169
IC50 (binding) = 25.1 nM Inhibition of oseltamivir-resistant Influenza A virus A/WSN/1933/H275Y(H1N1) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid as substrate incubated for 10 mins prior to substrate addition by fluorescence assay ChEMBL. 23009169
IC50 (binding) = 114 nM Inhibition of Influenza A virus A/Udorn/1972(H3N2) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid as substrate incubated for 10 mins prior to substrate addition by fluorescence assay ChEMBL. 23009169
IC50 (binding) = 131.7 nM Inhibition of Influenza A virus A/Taiwan/3446/2002(H3N2) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid as substrate incubated for 10 mins prior to substrate addition by fluorescence assay ChEMBL. 23009169
Vd/F (ADMET) = 20 L/Kg Apparent oral volume of distribution in mouse at 10 mg/kg ChEMBL. 23009169

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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