Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0474 | 0.0046 | 0.5 |
Echinococcus granulosus | tumor suppressor p53 binding protein 1 | 0.5339 | 0.3628 | 0.6089 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.1564 | 0.0848 | 0.1424 |
Schistosoma mansoni | sex comb on midleg homolog | 0.4336 | 0.2889 | 0.2889 |
Trypanosoma cruzi | Kinesin-13 5, putative | 0.0411 | 0 | 0.5 |
Echinococcus multilocularis | chromobox protein 2 | 0.3215 | 0.2065 | 0.3464 |
Echinococcus multilocularis | histone acetyltransferase myst3 | 0.0665 | 0.0186 | 0.0313 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.1564 | 0.0848 | 0.1635 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0441 | 0.0022 | 0.0022 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.1564 | 0.0848 | 0.0848 |
Onchocerca volvulus | 0.4923 | 0.3322 | 0.6402 | |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0441 | 0.0022 | 0.0036 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.1518 | 0.0815 | 0.1367 |
Trichomonas vaginalis | cgi-62, putative | 0.0411 | 0 | 0.5 |
Trypanosoma brucei | SAM domain (Sterile alpha motif), putative | 0.0411 | 0 | 0.5 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.4336 | 0.2889 | 0.4848 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.1564 | 0.0848 | 0.1424 |
Brugia malayi | jmjC domain containing protein | 0.0415 | 0.0002 | 0.0005 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.6279 | 0.432 | 0.725 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.1862 | 0.1068 | 0.1792 |
Loa Loa (eye worm) | hypothetical protein | 0.1564 | 0.0848 | 0.1635 |
Brugia malayi | mbt repeat family protein | 0.4512 | 0.3019 | 0.5818 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0415 | 0.0002 | 0.0004 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.4336 | 0.2889 | 0.4848 |
Echinococcus multilocularis | tumor suppressor p53 binding protein 1 | 0.5339 | 0.3628 | 0.6089 |
Loa Loa (eye worm) | mbt repeat family protein | 0.4512 | 0.3019 | 0.5818 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0415 | 0.0002 | 0.0004 |
Schistosoma mansoni | sex comb on midleg homolog | 0.4336 | 0.2889 | 0.2889 |
Trichomonas vaginalis | c2h2 zinc finger protein, putative | 0.0411 | 0 | 0.5 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.1564 | 0.0848 | 0.1424 |
Echinococcus granulosus | histone acetyltransferase myst3 | 0.0665 | 0.0186 | 0.0313 |
Trypanosoma cruzi | Kinesin-13 5, putative | 0.0411 | 0 | 0.5 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.8505 | 0.5959 | 1 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.6279 | 0.432 | 0.725 |
Trypanosoma cruzi | hypothetical protein | 0.0411 | 0 | 0.5 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.7459 | 0.5189 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0411 | 0 | 0.5 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.6279 | 0.432 | 0.432 |
Giardia lamblia | Kinesin-13 | 0.0411 | 0 | 0.5 |
Giardia lamblia | Giardia trophozoite antigen GTA-1 | 0.0411 | 0 | 0.5 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.8505 | 0.5959 | 1 |
Toxoplasma gondii | PLU-1 family protein | 0.0717 | 0.0225 | 1 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.1564 | 0.0848 | 0.1424 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.1518 | 0.0815 | 0.0815 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.1862 | 0.1068 | 0.1792 |
Schistosoma mansoni | jumonji domain containing protein | 0.0415 | 0.0002 | 0.0002 |
Schistosoma mansoni | phd finger protein | 0.0665 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.7459 | 0.5189 | 1 |
Brugia malayi | jmjC domain containing protein | 0.2235 | 0.1343 | 0.2588 |
Schistosoma mansoni | chromobox protein | 0.3215 | 0.2065 | 0.2065 |
Plasmodium vivax | JmjC domain containing protein | 0.0474 | 0.0046 | 1 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0528 | 0.0086 | 0.3694 |
Loa Loa (eye worm) | MBCTL1 | 0.1564 | 0.0848 | 0.1635 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0441 | 0.0022 | 0.0042 |
Brugia malayi | mbt repeat family protein | 0.7459 | 0.5189 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.1518 | 0.0815 | 0.0815 |
Schistosoma mansoni | hypothetical protein | 0.5339 | 0.3628 | 0.3628 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0441 | 0.0022 | 0.0036 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.2235 | 0.1343 | 0.2588 |
Echinococcus granulosus | chromobox protein 2 | 0.3215 | 0.2065 | 0.3464 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.1265 | 0.0628 | 0.1055 |
Trypanosoma brucei | Present in the outer mitochondrial membrane proteome 24 | 0.0411 | 0 | 0.5 |
Brugia malayi | CHD4 protein | 0.0441 | 0.0022 | 0.0042 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.