Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0103 | 0.1344 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0713 | 0.0777 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0066 | 0.0713 | 0.5234 |
Schistosoma mansoni | dual specificity serine/threonine tyrosine kinase | 0.0554 | 0.8948 | 0.8948 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0067 | 0.0745 | 0.0711 |
Schistosoma mansoni | rab6-interacting | 0.0103 | 0.1344 | 0.1344 |
Loa Loa (eye worm) | doublecortin family protein | 0.0103 | 0.1344 | 0.1502 |
Schistosoma mansoni | lipoxygenase | 0.0431 | 0.6872 | 0.6872 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0087 | 0.0515 |
Onchocerca volvulus | Dual specificity protein kinase TTK homolog | 0.0554 | 0.8948 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0103 | 0.1344 | 0.1312 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0066 | 0.0713 | 0.5 |
Schistosoma mansoni | polycystin 1-related | 0.0103 | 0.1344 | 0.1344 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0103 | 0.1344 | 1 |
Brugia malayi | hypothetical protein | 0.0348 | 0.548 | 0.6115 |
Toxoplasma gondii | aurora kinase | 0.0066 | 0.0713 | 0.4576 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0087 | 0.0515 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0066 | 0.0713 | 0.5 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0087 | 0.0076 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0103 | 0.1344 | 0.1312 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0103 | 0.1344 | 0.1312 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0713 | 0.0777 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0087 | 0.045 |
Onchocerca volvulus | 0.0103 | 0.1344 | 0.1484 | |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.0114 | 0.1535 | 0.1535 |
Trypanosoma brucei | aurora B kinase | 0.0066 | 0.0713 | 1 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0103 | 0.1344 | 0.1312 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.0499 | 0.8021 | 0.8021 |
Echinococcus multilocularis | dual specificity serine:threonine tyrosine | 0.0554 | 0.8948 | 0.8944 |
Echinococcus granulosus | RUN | 0.0103 | 0.1344 | 0.1312 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0066 | 0.0713 | 0.0679 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0713 | 0.0777 |
Echinococcus granulosus | dual specificity serine:threonine tyrosine | 0.0554 | 0.8948 | 0.8944 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0082 | 0.007 |
Schistosoma mansoni | loxhd1 | 0.0103 | 0.1344 | 0.1344 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0066 | 0.0713 | 0.0777 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0066 | 0.0713 | 0.0777 |
Brugia malayi | Protein kinase domain containing protein | 0.0554 | 0.8948 | 1 |
Brugia malayi | Doublecortin family protein | 0.0103 | 0.1344 | 0.1484 |
Loa Loa (eye worm) | TTK protein kinase | 0.0554 | 0.8948 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | AUR protein kinase | 0.0066 | 0.0713 | 0.0796 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0103 | 0.1344 | 0.1312 |
Entamoeba histolytica | protein kinase, putative | 0.0066 | 0.0713 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1344 | 0.1502 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0066 | 0.0713 | 0.5 |
Echinococcus multilocularis | aurora kinase A | 0.0066 | 0.0713 | 0.0679 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0554 | 0.8948 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0072 | 0.0813 | 0.0813 |
Giardia lamblia | Kinase, TTK | 0.0554 | 0.8948 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0338 | 0.0378 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0087 | 0.0515 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0103 | 0.1344 | 0.1312 |
Schistosoma mansoni | protein kinase | 0.0066 | 0.0713 | 0.0713 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0713 | 0.0777 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0066 | 0.0713 | 0.5 |
Brugia malayi | serine/threonine kinase 12 | 0.0066 | 0.0713 | 0.0777 |
Brugia malayi | Bromodomain containing protein | 0.0085 | 0.1037 | 0.114 |
Echinococcus granulosus | microsomal glutathione S transferase 3 | 0.0114 | 0.1535 | 0.1504 |
Entamoeba histolytica | protein kinase, putative | 0.0066 | 0.0713 | 0.5 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0066 | 0.0713 | 1 |
Entamoeba histolytica | protein kinase , putative | 0.0066 | 0.0713 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0383 | 0.0428 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0066 | 0.0713 | 0.5234 |
Toxoplasma gondii | MAPEG family protein | 0.0114 | 0.1535 | 1 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0066 | 0.0713 | 0.0679 |
Leishmania major | protein kinase, putative | 0.0066 | 0.0713 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0019 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.042 | 0.0469 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1344 | 0.1502 |
Schistosoma mansoni | rab6-interacting | 0.0103 | 0.1344 | 0.1344 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0292 | 0.0256 |
Brugia malayi | hypothetical protein | 0.0103 | 0.1344 | 0.1484 |
Brugia malayi | hypothetical protein | 0.0103 | 0.1344 | 0.1484 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0067 | 0.0745 | 0.0711 |
Loa Loa (eye worm) | AUR protein kinase | 0.0066 | 0.0713 | 0.0796 |
Loa Loa (eye worm) | hypothetical protein | 0.0348 | 0.548 | 0.6124 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0087 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0103 | 0.1344 | 0.1344 |
Loa Loa (eye worm) | AUR protein kinase | 0.0066 | 0.0713 | 0.0796 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0292 | 0.0256 |
Brugia malayi | Bromodomain containing protein | 0.0043 | 0.0337 | 0.0356 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0554 | 0.8948 | 1 |
Echinococcus granulosus | aurora kinase A | 0.0066 | 0.0713 | 0.0679 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.0114 | 0.1535 | 0.1504 |
Echinococcus multilocularis | RUN | 0.0103 | 0.1344 | 0.1312 |
Onchocerca volvulus | 0.0103 | 0.1344 | 0.1484 | |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0955 | 0.1068 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0713 | 0.0713 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.