Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0523 | 1 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0031 | 0.0169 | 0.0561 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0 | 0.5 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0067 | 0.0891 | 0.2957 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0023 | 0.0009 | 0.0029 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0023 | 0.0009 | 0.0029 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0067 | 0.0891 | 0.2957 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0067 | 0.0891 | 0.1052 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0067 | 0.0891 | 0.1868 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0067 | 0.0891 | 0.1052 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0009 | 0.0105 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1, putative | 0.0046 | 0.0467 | 0.0467 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0273 | 0.0332 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0031 | 0.0169 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0051 | 0.0569 | 0.0569 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0031 | 0.0169 | 0.0561 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0051 | 0.0569 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0009 | 0.0011 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0067 | 0.0891 | 0.1868 |
Brugia malayi | Cation transporter family protein | 0.0067 | 0.0891 | 0.1868 |
Loa Loa (eye worm) | RGS-3 protein | 0.0023 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0273 | 0.0332 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0023 | 0.0009 | 0.0011 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0067 | 0.0891 | 0.1052 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0023 | 0.0009 | 0.0018 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0067 | 0.0891 | 0.1868 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0023 | 0.0009 | 0.0011 |
Brugia malayi | Ectopic membrane ruffles in embryo protein 1 | 0.0064 | 0.0821 | 0.172 |
Brugia malayi | Cation transporter family protein | 0.0067 | 0.0891 | 0.1868 |
Echinococcus multilocularis | NEDD8 activating enzyme E1 catalytic subunit | 0.0064 | 0.0821 | 0.0969 |
Brugia malayi | Cation transporter family protein | 0.0067 | 0.0891 | 0.1868 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0031 | 0.0169 | 0.0199 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0067 | 0.0891 | 0.2957 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0 | 0.5 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0067 | 0.0891 | 0.1868 |
Loa Loa (eye worm) | LGC-31 protein | 0.0067 | 0.0891 | 0.1084 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0051 | 0.0569 | 0.6933 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0023 | 0.0009 | 0.001 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0023 | 0.0009 | 0.0018 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0169 | 0.0354 |
Toxoplasma gondii | NEDD8-activating enzyme E1 catalytic subunit | 0.0064 | 0.0821 | 1 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0169 | 0.0354 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0023 | 0.0009 | 0.0011 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0023 | 0.0009 | 0.001 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0031 | 0.0169 | 0.0561 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0023 | 0.0009 | 0.001 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0067 | 0.0891 | 0.1084 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0031 | 0.0169 | 0.0199 |
Brugia malayi | Neuronal acetylcholine receptor protein, alpha-2 chain precursor | 0.0031 | 0.0169 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0023 | 0.0009 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0023 | 0.0009 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0434 | 0.8222 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0273 | 0.0332 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0169 | 0.2918 | 0.3444 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0273 | 0.0332 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0067 | 0.0891 | 0.1052 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0067 | 0.0891 | 0.1052 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0047 | 0.0484 | 0.59 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0031 | 0.0169 | 0.0354 |
Echinococcus granulosus | nAChR subunit | 0.0036 | 0.0273 | 0.0322 |
Loa Loa (eye worm) | acetylcholine receptor protein | 0.0031 | 0.0169 | 0.0206 |
Schistosoma mansoni | ubiquitin-activating enzyme E1C | 0.0064 | 0.0821 | 0.2723 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Echinococcus granulosus | axis inhibition protein axin | 0.0023 | 0.0009 | 0.001 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0261 | 0.4772 | 1 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0036 | 0.0273 | 0.0572 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.4154 | 0.5052 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0036 | 0.0273 | 0.0572 |
Schistosoma mansoni | nAChR subunit | 0.0031 | 0.0169 | 0.0561 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0067 | 0.0891 | 0.1052 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0031 | 0.0169 | 0.0354 |
Echinococcus granulosus | NEDD8 activating enzyme E1 catalytic subunit | 0.0064 | 0.0821 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.4772 | 0.5804 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0023 | 0.0009 | 0.001 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0031 | 0.0169 | 0.0354 |
Loa Loa (eye worm) | ACC-1 protein | 0.0067 | 0.0891 | 0.1084 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Loa Loa (eye worm) | ectopic membrane ruffles in embryo protein 1 | 0.0064 | 0.0821 | 0.0999 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0067 | 0.0891 | 0.1868 |
Loa Loa (eye worm) | acetyltransferase | 0.0173 | 0.3015 | 0.3667 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0009 | 0.0009 |
Schistosoma mansoni | nAChR subunit | 0.0067 | 0.0891 | 0.2957 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0023 | 0.0009 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0031 | 0.0169 | 0.0561 |
Brugia malayi | PXA domain containing protein | 0.0023 | 0.0009 | 0.0018 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0067 | 0.0891 | 0.1052 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0273 | 0.0332 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0067 | 0.0891 | 0.1052 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0067 | 0.0891 | 0.1868 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0023 | 0.0009 | 0.0011 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0009 | 0.0009 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0169 | 0.0354 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0031 | 0.0169 | 0.0206 |
Entamoeba histolytica | ubiquitin-activating enzyme, putative | 0.0064 | 0.0821 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0067 | 0.0891 | 0.1052 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0023 | 0.0009 | 0.001 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0067 | 0.0891 | 0.1868 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Echinococcus multilocularis | nAChR subunit | 0.0067 | 0.0891 | 0.1052 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0023 | 0.0009 | 0.0029 |
Onchocerca volvulus | 0.0067 | 0.0891 | 1 | |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0023 | 0.0009 | 0.0018 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0023 | 0.0009 | 0.001 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0031 | 0.0169 | 0.0561 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0023 | 0.0009 | 0.001 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0023 | 0.0009 | 0.001 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0067 | 0.0891 | 0.1052 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0067 | 0.0891 | 0.1084 |
Schistosoma mansoni | regulator of G protein signaling | 0.0023 | 0.0009 | 0.0029 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0036 | 0.0273 | 0.0905 |
Brugia malayi | Acetylcholine receptor protein, alpha-like chain 1 precursor | 0.0031 | 0.0169 | 0.0354 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0009 | 0.0009 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0067 | 0.0891 | 0.1052 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0036 | 0.0273 | 0.0572 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0067 | 0.0891 | 0.1084 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0023 | 0.0009 | 0.001 |
Onchocerca volvulus | 0.0036 | 0.0273 | 0.1438 | |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0067 | 0.0891 | 0.1052 |
Loa Loa (eye worm) | ACC-1 protein | 0.0067 | 0.0891 | 0.1084 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0067 | 0.0891 | 0.1052 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0067 | 0.0891 | 0.1084 |
Onchocerca volvulus | 0.0067 | 0.0891 | 1 | |
Schistosoma mansoni | nAChR subunit | 0.0067 | 0.0891 | 0.2957 |
Loa Loa (eye worm) | neuronal acetylcholine receptor protein | 0.0031 | 0.0169 | 0.0206 |
Echinococcus granulosus | axis inhibition protein axin | 0.0023 | 0.0009 | 0.001 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0169 | 0.0354 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0067 | 0.0891 | 0.1052 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0051 | 0.0569 | 0.0672 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0067 | 0.0891 | 0.1052 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0067 | 0.0891 | 0.1052 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0523 | 1 | 1 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0023 | 0.0009 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0273 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0009 | 0.0011 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0067 | 0.0891 | 0.1052 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0067 | 0.0891 | 0.2957 |
Schistosoma mansoni | regulator of G protein signaling | 0.0023 | 0.0009 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0067 | 0.0891 | 0.1868 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0009 | 0.0011 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0031 | 0.0169 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Schistosoma mansoni | nAChR subunit | 0.0067 | 0.0891 | 0.2957 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0067 | 0.0891 | 0.1052 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0067 | 0.0891 | 0.2957 |
Schistosoma mansoni | nAChR subunit | 0.0067 | 0.0891 | 0.2957 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0523 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0067 | 0.0891 | 0.1868 |
Schistosoma mansoni | nAChR subunit | 0.0067 | 0.0891 | 0.2957 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0523 | 1 | 1 |
Echinococcus granulosus | nAChR subunit | 0.0067 | 0.0891 | 0.1052 |
Schistosoma mansoni | axis inhibition protein axin | 0.0023 | 0.0009 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0009 | 0.0011 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0067 | 0.0891 | 0.1052 |
Echinococcus granulosus | expressed protein | 0.0446 | 0.8472 | 1 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0023 | 0.0009 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0273 | 0.0332 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0031 | 0.0169 | 0.0199 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0173 | 0.3015 | 0.3558 |
Trypanosoma cruzi | hypothetical protein | 0.0523 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Trypanosoma brucei | nucleoside 2-deoxyribosyltransferase | 0.0523 | 1 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0023 | 0.0009 | 0.0029 |
Echinococcus multilocularis | expressed protein | 0.0446 | 0.8472 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0009 | 0.0105 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0009 | 0.0018 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0047 | 0.0484 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0051 | 0.0569 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0023 | 0.0009 | 0.0029 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0009 | 0.0009 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0023 | 0.0009 | 0.001 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0023 | 0.0009 | 0.0018 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0067 | 0.0891 | 0.2957 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0169 | 0.0354 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0023 | 0.0009 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Onchocerca volvulus | 0.0067 | 0.0891 | 1 | |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0067 | 0.0891 | 0.1868 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0273 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0067 | 0.0891 | 0.1868 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0067 | 0.0891 | 0.1868 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0023 | 0.0009 | 0.001 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0067 | 0.0891 | 0.1052 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0023 | 0.0009 | 0.0009 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0051 | 0.0569 | 0.6933 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0067 | 0.0891 | 0.1052 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0023 | 0.0009 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Onchocerca volvulus | 0.0067 | 0.0891 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0891 | 0.1084 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0009 | 0.0011 |
Onchocerca volvulus | Putative nachr subunit | 0.0067 | 0.0891 | 1 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0067 | 0.0891 | 0.1868 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0009 | 0.0105 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0047 | 0.0484 | 1 |
Onchocerca volvulus | 0.0067 | 0.0891 | 1 | |
Onchocerca volvulus | 0.0036 | 0.0273 | 0.1438 | |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0023 | 0.0009 | 0.001 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0036 | 0.0273 | 0.0905 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0023 | 0.0009 | 0.0018 |
Echinococcus multilocularis | nAChR subunit | 0.0036 | 0.0273 | 0.0322 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0067 | 0.0891 | 0.1868 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0036 | 0.0273 | 0.0332 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0022 | 0 | 0.5 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0067 | 0.0891 | 0.1868 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0067 | 0.0891 | 0.1084 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0036 | 0.0273 | 0.0905 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0173 | 0.3015 | 0.6317 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0009 | 0.0018 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0273 | 0.3323 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0067 | 0.0891 | 0.1052 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0036 | 0.0273 | 0.0572 |
Schistosoma mansoni | nAChR subunit | 0.0067 | 0.0891 | 0.2957 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0023 | 0.0009 | 0.001 |
Schistosoma mansoni | axis inhibition protein axin | 0.0023 | 0.0009 | 0.0029 |
Schistosoma mansoni | nAChR subunit | 0.0067 | 0.0891 | 0.2957 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0067 | 0.0891 | 0.1052 |
Trypanosoma cruzi | hypothetical protein | 0.0523 | 1 | 1 |
Brugia malayi | PXA domain containing protein | 0.0023 | 0.0009 | 0.0018 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0023 | 0.0009 | 0.001 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0173 | 0.3015 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0023 | 0.0009 | 0.0029 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0067 | 0.0891 | 0.1052 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0031 | 0.0169 | 0.0199 |
Schistosoma mansoni | regulator of G protein signaling | 0.0023 | 0.0009 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0169 | 0.0206 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0067 | 0.0891 | 0.1052 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0067 | 0.0891 | 0.1868 |
Onchocerca volvulus | 0.0067 | 0.0891 | 1 | |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0067 | 0.0891 | 0.1084 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Blood glucose (functional) | = 88 % | Hypoglycemic activity was tested in rats at a standard dose of 100 mg/kg and calculated as percent of vehicle control after 2 hours (six rats per group) | ChEMBL. | 1560431 |
Blood glucose (functional) | = 95 % | Hypoglycemic activity was tested in rats at a standard dose of 100 mg/kg and calculated as percent of vehicle control after 4 hours (six rats per group) | ChEMBL. | 1560431 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.