Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.194 | 0.2407 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0703 | 0.1156 |
Trypanosoma brucei | Fibronectin type III domain containing protein, putative | 0.0025 | 0 | 0.5 |
Schistosoma mansoni | titin | 0.0032 | 0.194 | 0.2407 |
Echinococcus multilocularis | neuroglian | 0.0027 | 0.0662 | 0.0662 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0032 | 0.194 | 0.3192 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.1982 | 0.326 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0039 | 0.3922 | 0.4866 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.194 | 0.3192 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0033 | 0.2163 | 0.2163 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.194 | 0.3192 |
Trypanosoma cruzi | Fibronectin type III domain containing protein, putative | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0039 | 0.3922 | 0.3922 |
Echinococcus multilocularis | roundabout 2 | 0.0059 | 1 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.194 | 0.3192 |
Onchocerca volvulus | 0.0032 | 0.194 | 1 | |
Brugia malayi | Fibronectin type III domain containing protein | 0.0046 | 0.6078 | 1 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0035 | 0.2866 | 0.4715 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.2643 | 0.4349 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.194 | 0.3192 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.194 | 0.3192 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0032 | 0.194 | 0.3192 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0032 | 0.1982 | 0.326 |
Echinococcus granulosus | neuroglian | 0.0039 | 0.3922 | 0.3922 |
Echinococcus multilocularis | roundabout 2 | 0.0039 | 0.3922 | 0.3922 |
Echinococcus granulosus | titin | 0.0032 | 0.194 | 0.194 |
Onchocerca volvulus | 0.0032 | 0.194 | 1 | |
Echinococcus multilocularis | Down syndrome cell adhesion molecule | 0.0032 | 0.1982 | 0.1982 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0039 | 0.3922 | 0.3922 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0032 | 0.194 | 0.3192 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.6078 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0032 | 0.194 | 0.3192 |
Echinococcus multilocularis | transfer RNA-Phe | 0.0032 | 0.194 | 0.194 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.194 | 0.3192 |
Schistosoma mansoni | cell adhesion molecule | 0.0053 | 0.806 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0039 | 0.3922 | 0.3922 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0039 | 0.3922 | 0.6452 |
Echinococcus granulosus | roundabout 2 | 0.0039 | 0.3922 | 0.3922 |
Schistosoma mansoni | cell adhesion molecule | 0.0039 | 0.3922 | 0.4866 |
Schistosoma mansoni | cell adhesion molecule | 0.0039 | 0.3922 | 0.4866 |
Schistosoma mansoni | titin | 0.0032 | 0.194 | 0.2407 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0046 | 0.6078 | 1 |
Echinococcus granulosus | titin | 0.0032 | 0.194 | 0.194 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.194 | 0.3192 |
Echinococcus granulosus | Down syndrome cell adhesion molecule | 0.0032 | 0.1982 | 0.1982 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0032 | 0.194 | 0.194 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0039 | 0.3922 | 0.6452 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0035 | 0.2866 | 0.4715 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | roundabout 2 | 0.0039 | 0.3922 | 0.3922 |
Brugia malayi | protein unc-22 | 0.0032 | 0.194 | 0.3192 |
Trypanosoma cruzi | Fibronectin type III domain containing protein, putative | 0.0025 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.3922 | 0.6452 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0 | 0.5 |
Echinococcus granulosus | roundabout 2 | 0.0039 | 0.3922 | 0.3922 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0032 | 0.194 | 0.2407 |
Echinococcus granulosus | contactin | 0.0039 | 0.3922 | 0.3922 |
Echinococcus granulosus | twitchin | 0.0027 | 0.0662 | 0.0662 |
Schistosoma mansoni | neuroglian | 0.0039 | 0.3922 | 0.4866 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0039 | 0.3922 | 0.3922 |
Echinococcus granulosus | neuroglian | 0.0027 | 0.0662 | 0.0662 |
Schistosoma mansoni | cell adhesion molecule | 0.0032 | 0.194 | 0.2407 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.194 | 0.3192 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0039 | 0.3922 | 0.3922 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.6078 | 1 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0028 | 0.0703 | 0.0703 |
Loa Loa (eye worm) | projectin | 0.0032 | 0.194 | 0.3192 |
Schistosoma mansoni | hemicentin | 0.0032 | 0.194 | 0.2407 |
Onchocerca volvulus | 0.0032 | 0.194 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.2643 | 0.4349 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.6078 | 1 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0033 | 0.2163 | 0.2163 |
Schistosoma mansoni | cell adhesion molecule | 0.0032 | 0.194 | 0.2407 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0039 | 0.3922 | 0.6452 |
Schistosoma mansoni | myosin-binding protein-related | 0.0032 | 0.194 | 0.2407 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0039 | 0.3922 | 0.6452 |
Schistosoma mansoni | nephrin | 0.0053 | 0.8018 | 0.9949 |
Schistosoma mansoni | nephrin | 0.0039 | 0.3922 | 0.4866 |
Brugia malayi | hypothetical protein | 0.0046 | 0.6078 | 1 |
Schistosoma mansoni | ephrin receptor | 0.0033 | 0.2163 | 0.2684 |
Echinococcus granulosus | nephrin | 0.0032 | 0.194 | 0.194 |
Echinococcus multilocularis | neuroglian | 0.0039 | 0.3922 | 0.3922 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.194 | 0.3192 |
Echinococcus multilocularis | titin | 0.0032 | 0.194 | 0.194 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0039 | 0.3922 | 0.6452 |
Loa Loa (eye worm) | CAMK protein kinase | 0.0032 | 0.194 | 0.3192 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.