Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | probable isochorismate synthase EntC | 0.0067 | 0.0052 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0042 | 0.8004 |
Loa Loa (eye worm) | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0052 |
Brugia malayi | Cell death protein 3 precursor | 0.0058 | 0.0027 | 0.5268 |
Toxoplasma gondii | aurora kinase | 0.0063 | 0.0042 | 0.8004 |
Mycobacterium leprae | conserved hypothetical protein | 0.0067 | 0.0052 | 0.5 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0063 | 0.0042 | 0.8004 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Echinococcus multilocularis | caspase | 0.0215 | 0.0428 | 0.0402 |
Trypanosoma cruzi | glycerolphosphate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0067 | 0.0052 | 0.0025 |
Leishmania major | phosphoglycerate mutase family member 5, putative | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3914 | 0.9829 | 0.9829 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1699 | 0.4199 | 0.4183 |
Trypanosoma brucei | metacaspase MCA2 | 0.0058 | 0.0027 | 0.0027 |
Trypanosoma brucei | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.3914 | 0.9829 | 0.9829 |
Echinococcus granulosus | caspase | 0.0215 | 0.0428 | 0.0402 |
Echinococcus multilocularis | aurora kinase A | 0.0063 | 0.0042 | 0.0014 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.3981 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqD | 0.0067 | 0.0052 | 0.5 |
Trypanosoma cruzi | phosphoglycerate mutase family member 5, putative | 0.0067 | 0.0052 | 0.0025 |
Loa Loa (eye worm) | AUR protein kinase | 0.0063 | 0.0042 | 0.0042 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0052 | 0.0052 |
Onchocerca volvulus | 0.3981 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0052 | 0.0052 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Leishmania major | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0063 | 0.0042 | 0.0014 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Mycobacterium leprae | POSSIBLE HYDROLASE MUTT1 | 0.0067 | 0.0052 | 0.5 |
Treponema pallidum | phosphoglyceromutase | 0.0067 | 0.0052 | 0.5 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0215 | 0.0428 | 0.0402 |
Trypanosoma brucei | phosphoglycerate mutase protein, putative | 0.0067 | 0.0052 | 0.0052 |
Chlamydia trachomatis | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | 0.0067 | 0.0052 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Echinococcus multilocularis | caspase 3 | 0.0158 | 0.0282 | 0.0255 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0025 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0063 | 0.0042 | 0.8004 |
Loa Loa (eye worm) | AUR protein kinase | 0.0063 | 0.0042 | 0.0042 |
Trypanosoma brucei | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0052 |
Entamoeba histolytica | protein kinase , putative | 0.0063 | 0.0042 | 0.0071 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0063 | 0.0042 | 0.0014 |
Trypanosoma brucei | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0052 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Mycobacterium tuberculosis | Conserved protein | 0.0067 | 0.0052 | 0.5 |
Trypanosoma cruzi | glycerolphosphate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Onchocerca volvulus | 0.0067 | 0.0052 | 0.0025 | |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3981 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Onchocerca volvulus | 0.0067 | 0.0052 | 0.0025 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0067 | 0.0052 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3981 | 1 | 1 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3981 | 1 | 1 |
Leishmania major | fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein | 0.0067 | 0.0052 | 0.0025 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0063 | 0.0042 | 0.0071 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Echinococcus granulosus | aurora kinase A | 0.0063 | 0.0042 | 0.0014 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3981 | 1 | 1 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.235 | 0.5853 | 1 |
Mycobacterium leprae | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0067 | 0.0052 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Trypanosoma brucei | glycerolphosphate mutase, putative | 0.0067 | 0.0052 | 0.0052 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0025 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0063 | 0.0042 | 0.0071 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0063 | 0.0042 | 0.0071 |
Trypanosoma brucei | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 0.0052 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative | 0.0067 | 0.0052 | 0.0025 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0067 | 0.0052 | 0.0089 |
Toxoplasma gondii | phosphoglycerate mutase PGMII | 0.0067 | 0.0052 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0042 | 0.8004 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative | 0.0067 | 0.0052 | 0.0052 |
Trypanosoma brucei | Metacaspase-4 | 0.0058 | 0.0027 | 0.0027 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0063 | 0.0042 | 0.0014 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein | 0.1699 | 0.4199 | 0.4183 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Echinococcus granulosus | caspase 3 | 0.0158 | 0.0282 | 0.0255 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.3914 | 0.9829 | 0.9829 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0063 | 0.0042 | 0.5782 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0067 | 0.0052 | 0.0089 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0063 | 0.0042 | 0.5782 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3981 | 1 | 1 |
Trypanosoma cruzi | phosphoglycerate mutase family member 5, putative | 0.0067 | 0.0052 | 0.0025 |
Leishmania major | hypothetical protein, unknown function | 0.0067 | 0.0052 | 0.0025 |
Schistosoma mansoni | protein kinase | 0.0063 | 0.0042 | 0.0014 |
Leishmania major | phosphoglycerate mutase protein, putative | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | phosphoglycerate mutase protein, putative | 0.0067 | 0.0052 | 0.0025 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3914 | 0.9829 | 0.9829 |
Mycobacterium tuberculosis | PE-PGRS family protein PE_PGRS11 | 0.0067 | 0.0052 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0052 | 0.0025 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0063 | 0.0042 | 0.0014 |
Entamoeba histolytica | protein kinase, putative | 0.0063 | 0.0042 | 0.0071 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Trypanosoma cruzi | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0067 | 0.0052 | 0.0025 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0063 | 0.0042 | 0.0071 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative | 0.0067 | 0.0052 | 0.0025 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0058 | 0.0027 | 0.5268 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Brugia malayi | UBASH3A protein homolog | 0.0067 | 0.0052 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0027 | 0.0027 |
Trypanosoma cruzi | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0058 | 0.0027 | 0.5268 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium tuberculosis | Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) | 0.0067 | 0.0052 | 0.5 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium tuberculosis | Possible hydrolase MutT1 | 0.0067 | 0.0052 | 0.5 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium ulcerans | hypothetical protein | 0.235 | 0.5853 | 1 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium leprae | conserved hypothetical protein | 0.0067 | 0.0052 | 0.5 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0067 | 0.0052 | 0.0025 |
Entamoeba histolytica | phosphoglycerate mutase family protein. putative | 0.0067 | 0.0052 | 0.0089 |
Plasmodium falciparum | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2282 | 0.5682 | 0.5682 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) | 0.0067 | 0.0052 | 0.5 |
Mycobacterium tuberculosis | Glucosyl-3-phosphoglycerate phosphatase GpgP | 0.0067 | 0.0052 | 0.5 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0215 | 0.0428 | 0.0402 |
Trypanosoma cruzi | phosphoglycerate mutase protein, putative | 0.0067 | 0.0052 | 0.0025 |
Leishmania major | protein kinase, putative | 0.0063 | 0.0042 | 0.0014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0067 | 0.0052 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0067 | 0.0052 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0067 | 0.0052 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1699 | 0.4199 | 0.4183 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0052 | 0.0052 |
Leishmania major | glycerolphosphate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Giardia lamblia | Hypothetical protein | 0.235 | 0.5853 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0067 | 0.0052 | 0.0025 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Brugia malayi | serine/threonine kinase 12 | 0.0063 | 0.0042 | 0.8004 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0215 | 0.0428 | 0.0402 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0067 | 0.0052 | 0.0025 |
Giardia lamblia | Hypothetical protein | 0.235 | 0.5853 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0067 | 0.0052 | 0.5 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Trypanosoma brucei | metacaspase MCA3 | 0.0058 | 0.0027 | 0.0027 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0052 | 0.0025 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0067 | 0.0052 | 0.0025 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma brucei | aurora B kinase | 0.0063 | 0.0042 | 0.0042 |
Entamoeba histolytica | protein kinase, putative | 0.0063 | 0.0042 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0052 | 0.0052 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0215 | 0.0428 | 0.0402 |
Trypanosoma brucei | metacaspase 5, putative | 0.0058 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0042 | 0.8004 |
Mycobacterium leprae | Possible phosphoglycerate mutase | 0.0067 | 0.0052 | 0.5 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma brucei | metacaspase | 0.0058 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | AUR protein kinase | 0.0063 | 0.0042 | 0.0042 |
Plasmodium falciparum | phosphoglucomutase-2 | 0.0067 | 0.0052 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1699 | 0.4199 | 0.4199 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Plasmodium vivax | phosphoglucomutase-2, putative | 0.0067 | 0.0052 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0027 | 0.0027 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) | 0.0067 | 0.0052 | 0.5 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Plasmodium vivax | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Onchocerca volvulus | 0.0067 | 0.0052 | 0.0025 | |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0058 | 0.0027 | 0.5268 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Mycobacterium tuberculosis | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0067 | 0.0052 | 0.5 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3914 | 0.9829 | 0.9829 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0058 | 0.0027 | 0.5268 |
Trypanosoma brucei | Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative | 0.0067 | 0.0052 | 0.0052 |
Toxoplasma gondii | phosphoglycerate mutase | 0.0067 | 0.0052 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.3981 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0042 | 0.8004 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.235 | 0.5853 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.