Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.2282 | 0.5682 | 0.5682 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3914 | 0.9829 | 0.9829 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0067 | 0.0052 | 0.0025 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0052 | 0.0025 |
Onchocerca volvulus | 0.0067 | 0.0052 | 0.0025 | |
Leishmania major | hypothetical protein, unknown function | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | phosphoglycerate mutase protein, putative | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma brucei | metacaspase MCA3 | 0.0058 | 0.0027 | 0.0027 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.235 | 0.5853 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqD | 0.0067 | 0.0052 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0063 | 0.0042 | 0.0014 |
Plasmodium falciparum | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0025 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0215 | 0.0428 | 0.0402 |
Echinococcus multilocularis | aurora kinase A | 0.0063 | 0.0042 | 0.0014 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Entamoeba histolytica | protein kinase, putative | 0.0063 | 0.0042 | 0.0071 |
Leishmania major | protein kinase, putative | 0.0063 | 0.0042 | 0.0014 |
Brugia malayi | Cell death protein 3 precursor | 0.0058 | 0.0027 | 0.5268 |
Echinococcus granulosus | caspase 3 | 0.0158 | 0.0282 | 0.0255 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0067 | 0.0052 | 0.0089 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0067 | 0.0052 | 0.0089 |
Echinococcus granulosus | aurora kinase A | 0.0063 | 0.0042 | 0.0014 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0067 | 0.0052 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.235 | 0.5853 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0027 | 0.0027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Echinococcus granulosus | caspase | 0.0215 | 0.0428 | 0.0402 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3914 | 0.9829 | 0.9829 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.3914 | 0.9829 | 0.9829 |
Trypanosoma brucei | metacaspase | 0.0058 | 0.0027 | 0.0027 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0025 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0063 | 0.0042 | 0.0014 |
Mycobacterium leprae | conserved hypothetical protein | 0.0067 | 0.0052 | 0.5 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0058 | 0.0027 | 0.5268 |
Trypanosoma brucei | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0052 |
Trypanosoma brucei | metacaspase MCA2 | 0.0058 | 0.0027 | 0.0027 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3914 | 0.9829 | 0.9829 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium tuberculosis | Conserved protein | 0.0067 | 0.0052 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Trypanosoma cruzi | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0215 | 0.0428 | 0.0402 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3981 | 1 | 1 |
Trypanosoma brucei | aurora B kinase | 0.0063 | 0.0042 | 0.0042 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Loa Loa (eye worm) | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0052 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0067 | 0.0052 | 0.0025 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0067 | 0.0052 | 0.0025 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0058 | 0.0027 | 0.5268 |
Trypanosoma brucei | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0052 |
Brugia malayi | UBASH3A protein homolog | 0.0067 | 0.0052 | 1 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0063 | 0.0042 | 0.5782 |
Mycobacterium tuberculosis | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0067 | 0.0052 | 0.5 |
Echinococcus multilocularis | caspase 3 | 0.0158 | 0.0282 | 0.0255 |
Mycobacterium leprae | probable isochorismate synthase EntC | 0.0067 | 0.0052 | 0.5 |
Leishmania major | fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium tuberculosis | Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) | 0.0067 | 0.0052 | 0.5 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0058 | 0.0027 | 0.5268 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0063 | 0.0042 | 0.5782 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3914 | 0.9829 | 0.9829 |
Mycobacterium tuberculosis | Possible hydrolase MutT1 | 0.0067 | 0.0052 | 0.5 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0042 | 0.8004 |
Trypanosoma cruzi | phosphoglycerate mutase family member 5, putative | 0.0067 | 0.0052 | 0.0025 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3981 | 1 | 1 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0063 | 0.0042 | 0.8004 |
Brugia malayi | serine/threonine kinase 12 | 0.0063 | 0.0042 | 0.8004 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative | 0.0067 | 0.0052 | 0.0025 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0063 | 0.0042 | 0.0071 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0067 | 0.0052 | 1 |
Mycobacterium leprae | POSSIBLE HYDROLASE MUTT1 | 0.0067 | 0.0052 | 0.5 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0067 | 0.0052 | 0.0025 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Trypanosoma brucei | phosphoglycerate mutase protein, putative | 0.0067 | 0.0052 | 0.0052 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3981 | 1 | 1 |
Toxoplasma gondii | phosphoglycerate mutase | 0.0067 | 0.0052 | 1 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.3981 | 1 | 1 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) | 0.0067 | 0.0052 | 0.5 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0067 | 0.0052 | 0.0025 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma brucei | Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative | 0.0067 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0052 | 0.0052 |
Treponema pallidum | phosphoglyceromutase | 0.0067 | 0.0052 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0063 | 0.0042 | 0.0042 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0063 | 0.0042 | 0.8004 |
Trypanosoma cruzi | glycerolphosphate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Entamoeba histolytica | protein kinase , putative | 0.0063 | 0.0042 | 0.0071 |
Onchocerca volvulus | 0.0067 | 0.0052 | 0.0025 | |
Toxoplasma gondii | phosphoglycerate mutase PGMII | 0.0067 | 0.0052 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1699 | 0.4199 | 0.4199 |
Mycobacterium leprae | conserved hypothetical protein | 0.0067 | 0.0052 | 0.5 |
Mycobacterium tuberculosis | Glucosyl-3-phosphoglycerate phosphatase GpgP | 0.0067 | 0.0052 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0063 | 0.0042 | 0.0042 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0067 | 0.0052 | 0.0025 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0052 | 0.0052 |
Plasmodium vivax | phosphoglucomutase-2, putative | 0.0067 | 0.0052 | 1 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0215 | 0.0428 | 0.0402 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3981 | 1 | 1 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0063 | 0.0042 | 0.0071 |
Mycobacterium leprae | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0067 | 0.0052 | 0.5 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma brucei | metacaspase 5, putative | 0.0058 | 0.0027 | 0.0027 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0042 | 0.8004 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0067 | 0.0052 | 1 |
Trypanosoma brucei | glycerolphosphate mutase, putative | 0.0067 | 0.0052 | 0.0052 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0063 | 0.0042 | 0.0014 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0063 | 0.0042 | 0.0071 |
Toxoplasma gondii | aurora kinase | 0.0063 | 0.0042 | 0.8004 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1699 | 0.4199 | 0.4183 |
Giardia lamblia | Hypothetical protein | 0.235 | 0.5853 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0042 | 0.8004 |
Loa Loa (eye worm) | AUR protein kinase | 0.0063 | 0.0042 | 0.0042 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Schistosoma mansoni | 6-phosphofructokinase | 0.3981 | 1 | 1 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Trypanosoma cruzi | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1699 | 0.4199 | 0.4183 |
Leishmania major | phosphoglycerate mutase protein, putative | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma cruzi | phosphoglycerate mutase protein, putative | 0.0067 | 0.0052 | 0.0025 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Schistosoma mansoni | protein kinase | 0.0063 | 0.0042 | 0.0014 |
Mycobacterium tuberculosis | PE-PGRS family protein PE_PGRS11 | 0.0067 | 0.0052 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0063 | 0.0042 | 0.0071 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma brucei | Histidine phosphatase superfamily (branch 1), putative | 0.0067 | 0.0052 | 0.0052 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0052 | 0.0025 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Trypanosoma brucei | Metacaspase-4 | 0.0058 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Plasmodium vivax | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Trypanosoma cruzi | phosphoglycerate mutase family member 5, putative | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.235 | 0.5853 | 1 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0215 | 0.0428 | 0.0402 |
Leishmania major | phosphoglycerate mutase family member 5, putative | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative | 0.0067 | 0.0052 | 0.0052 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Trypanosoma brucei | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 0.0052 |
Leishmania major | glycerolphosphate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) | 0.0067 | 0.0052 | 0.5 |
Trypanosoma cruzi | glycerolphosphate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein | 0.1699 | 0.4199 | 0.4183 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0058 | 0.0027 | 0.5268 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0052 | 0.0052 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0058 | 0.0027 | 0.5268 |
Mycobacterium tuberculosis | Conserved protein | 0.0067 | 0.0052 | 0.5 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0027 | 0.0027 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0067 | 0.0052 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0063 | 0.0042 | 0.0071 |
Entamoeba histolytica | phosphoglycerate mutase family protein. putative | 0.0067 | 0.0052 | 0.0089 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0058 | 0.0027 | 0.5268 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0052 | 0.0052 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0067 | 0.0052 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.3981 | 1 | 1 |
Echinococcus multilocularis | caspase | 0.0215 | 0.0428 | 0.0402 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0063 | 0.0042 | 0.8004 |
Chlamydia trachomatis | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | 0.0067 | 0.0052 | 0.5 |
Mycobacterium leprae | Possible phosphoglycerate mutase | 0.0067 | 0.0052 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0067 | 0.0052 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.235 | 0.5853 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0052 | 0.0025 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0067 | 0.0052 | 0.0025 |
Onchocerca volvulus | 0.3981 | 1 | 1 | |
Onchocerca volvulus | 0.0067 | 0.0052 | 0.0025 | |
Leishmania major | phosphoglycerate mutase, putative | 0.0067 | 0.0052 | 0.0025 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0063 | 0.0042 | 0.0014 |
Plasmodium falciparum | phosphoglucomutase-2 | 0.0067 | 0.0052 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.