Detailed information for compound 1829469

Basic information

Technical information
  • TDR Targets ID: 1829469
  • Name: 1,3-dihydroxy-2-methoxyxanthen-9-one
  • MW: 258.226 | Formula: C14H10O5
  • H donors: 2 H acceptors: 3 LogP: 2.77 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1c(O)cc2c(c1O)c(=O)c1c(o2)cccc1
  • InChi: 1S/C14H10O5/c1-18-14-8(15)6-10-11(13(14)17)12(16)7-4-2-3-5-9(7)19-10/h2-6,15,17H,1H3
  • InChiKey: PVNLFOMDIZUYGA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1,3-dihydroxy-2-methoxy-xanthen-9-one
  • 1,3-dihydroxy-2-methoxy-9-xanthenone
  • 1,3-dihydroxy-2-methoxy-xanthone
  • 1,3-Dihydroxy-2-methoxy xanthone
  • 6,8-Dihydroxy-7-methoxyxanthone
  • AIDS-122700
  • AIDS122700

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Calcitonin receptor-like protein seb-1 0.0147 0.1459 0.1403
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Brugia malayi Inositol-1 0.0073 0.0538 0.0475
Trypanosoma brucei Casein kinase II 0.0833 1 1
Mycobacterium leprae Possible transporter protein 0.0079 0.0609 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0448 0.0385
Echinococcus granulosus GPCR family 2 0.0046 0.021 0.0145
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0062 0.0408 0.0345
Trichomonas vaginalis adenylate cyclase type, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate cyclase type III, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0079 0.0609 0.0547
Echinococcus multilocularis microtubule associated protein 2 0.0669 0.795 0.7937
Echinococcus multilocularis inositol monophosphatase 1 0.0073 0.0538 0.0475
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.1325 0.1267
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0049 0.0247 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0609 0.0547
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Schistosoma mansoni voltage-gated potassium channel 0.0079 0.0609 0.0547
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0188 0.1965 0.1912
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0046 0.021 0.0145
Trichomonas vaginalis adenylate cyclase type III, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0833 1 1
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Brugia malayi calpain family protein 1 0.0062 0.0408 0.0345
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0359 0.0295
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0079 0.0609 0.0547
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.1325 0.1267
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0306 0.0242
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0065 0.0443 0.6937
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0066 0.0448 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0609 0.0547
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0609 0.0547
Loa Loa (eye worm) calpain family protein 1 0.0044 0.0177 0.0112
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0046 0.021 0.0145
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0066 0.0448 0.0385
Brugia malayi calpain family protein 1 0.0062 0.0408 0.0345
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0306 0.0242
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.1325 0.1267
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Onchocerca volvulus 0.0044 0.0177 0.0118
Plasmodium vivax unspecified product 0.0833 1 1
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0079 0.0609 0.0547
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0448 0.0385
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0359 0.0295
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0079 0.0609 0.0547
Echinococcus multilocularis voltage gated potassium channel 0.0079 0.0609 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0833 1 1
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0079 0.0609 0.0547
Echinococcus granulosus microtubule associated protein 2 0.0669 0.795 0.7937
Loa Loa (eye worm) hypothetical protein 0.0049 0.0247 0.0183
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0079 0.0609 0.0547
Echinococcus multilocularis neuropeptide receptor A26 0.0448 0.5206 0.5174
Brugia malayi hypothetical protein 0.0466 0.5431 0.5401
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0306 0.0242
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0538 0.0475
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0359 0.0295
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0079 0.0609 0.0547
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0609 0.0547
Echinococcus multilocularis muscleblind protein 1 0.0146 0.1443 0.1386
Schistosoma mansoni voltage-gated potassium channel 0.0079 0.0609 0.0547
Echinococcus granulosus casein kinase ii subunit alpha 0.0833 1 1
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0538 0.0475
Entamoeba histolytica hypothetical protein 0.0035 0.0065 0.0065
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0079 0.0609 0.0547
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.1325 0.1267
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0609 0.0547
Entamoeba histolytica hypothetical protein 0.0035 0.0065 0.0065
Schistosoma mansoni hypothetical protein 0.0079 0.0609 0.0547
Loa Loa (eye worm) calpain family protein 1 0.0062 0.0408 0.0345
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0079 0.0609 0.0547
Entamoeba histolytica hypothetical protein 0.0035 0.0065 0.0065
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0049 0.0247 0.0183
Schistosoma mansoni voltage-gated potassium channel 0.0079 0.0609 0.0547
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.2405 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0538 0.0475
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0073 0.0538 0.0475
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0609 0.0547
Schistosoma mansoni inositol monophosphatase 0.0073 0.0538 0.0475
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate cyclase type, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Schistosoma mansoni voltage-gated potassium channel 0.0079 0.0609 0.0547
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0147 0.1459 0.1402
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0359 0.0295
Loa Loa (eye worm) hypothetical protein 0.0046 0.021 0.0145
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0306 0.0242
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.1325 0.1267
Brugia malayi jmjC domain containing protein 0.0058 0.0359 0.0295
Schistosoma mansoni cathepsin D (A01 family) 0.0146 0.1447 0.1391
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0079 0.0609 0.0547
Loa Loa (eye worm) hypothetical protein 0.0079 0.0609 0.0547
Schistosoma mansoni hypothetical protein 0.0046 0.021 0.0145
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Echinococcus granulosus neuropeptide s receptor 0.0448 0.5206 0.5174
Brugia malayi mbt repeat family protein 0.0048 0.0224 0.0159
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0049 0.0247 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0609 0.0547
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.1325 0.1267
Echinococcus granulosus calpain A 0.0066 0.0448 0.0385
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0224 0.0159
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0224 0.0159
Toxoplasma gondii aspartyl protease ASP1 0.0049 0.0247 0.0183
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Echinococcus multilocularis casein kinase ii subunit alpha 0.0833 1 1
Leishmania major casein kinase II, putative 0.0833 1 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0224 0.0159
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0306 0.0242
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.1325 0.1267
Schistosoma mansoni hypothetical protein 0.0095 0.0815 0.0754
Brugia malayi latrophilin 2 splice variant baaae 0.01 0.0881 0.0821
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0049 0.0247 0.0183
Onchocerca volvulus 0.0095 0.0815 0.0796
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0079 0.0609 0.0547
Schistosoma mansoni 60S ribosomal protein L21 0.0079 0.0609 0.0547
Echinococcus multilocularis calpain A 0.0066 0.0448 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0609 0.0547
Schistosoma mansoni hypothetical protein 0.0046 0.021 0.0145
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0046 0.021 0.0145
Trichomonas vaginalis CMGC family protein kinase 0.0833 1 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0049 0.0247 0.0183
Loa Loa (eye worm) hypothetical protein 0.0147 0.1459 0.1402
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0813 0.9745 0.9744
Entamoeba histolytica protein kinase domain containing protein 0.0833 1 1
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0079 0.0609 0.0547
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0188 0.1965 0.1912
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0224 0.0159
Schistosoma mansoni survival motor neuron protein 0.0095 0.0815 0.0754
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Plasmodium falciparum casein kinase 2, alpha subunit 0.0833 1 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.1325 0.1267
Echinococcus granulosus muscleblind protein 0.0146 0.1443 0.1386
Echinococcus granulosus inositol monophosphatase 1 0.0073 0.0538 0.0475
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0224 0.0159
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0079 0.0609 0.0547
Entamoeba histolytica casein kinase, putative 0.0833 1 1
Schistosoma mansoni cathepsin D (A01 family) 0.0146 0.1447 0.1391
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.009 0.0746 0.0685
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0791 0.9475 0.9472
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0815 0.0754
Onchocerca volvulus 0.0048 0.0224 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0609 0.0547
Loa Loa (eye worm) hypothetical protein 0.0062 0.0408 0.0345
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0359 0.0295
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0147 0.1459 0.1403
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0538 0.0475
Echinococcus multilocularis survival motor neuron protein 1 0.0466 0.5431 0.5401
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0079 0.0609 0.0547
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0224 0.0159
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0224 0.0168
Echinococcus granulosus neuropeptide receptor A26 0.0448 0.5206 0.5174
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Loa Loa (eye worm) hypothetical protein 0.0054 0.0306 0.0242
Brugia malayi mbt repeat family protein 0.0048 0.0224 0.0159
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0079 0.0609 0.0547
Loa Loa (eye worm) hypothetical protein 0.0044 0.0177 0.0112
Trichomonas vaginalis hypothetical protein 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate cyclase type, putative 0.0079 0.0609 0.0547
Loa Loa (eye worm) hypothetical protein 0.0048 0.0224 0.0159
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0046 0.021 0.0145
Loa Loa (eye worm) latrophilin receptor protein 2 0.0046 0.021 0.0145
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0224 0.0159
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0073 0.0538 0.5
Toxoplasma gondii CMGC kinase, CK2 family 0.0833 1 1
Schistosoma mansoni hypothetical protein 0.0046 0.021 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0609 0.0547
Echinococcus multilocularis calpain family protein 1, d 0.0044 0.0177 0.0113
Trichomonas vaginalis CMGC family protein kinase 0.0833 1 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0079 0.0609 0.0547
Echinococcus granulosus single minded 2 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0079 0.0609 0.0547
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0306 0.0242
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0049 0.0247 0.0183
Schistosoma mansoni hypothetical protein 0.01 0.0881 0.0821
Trichomonas vaginalis inositol monophosphatase, putative 0.0073 0.0538 0.0475
Trichomonas vaginalis CMGC family protein kinase 0.0833 1 1
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0833 1 1
Entamoeba histolytica hypothetical protein 0.0035 0.0065 0.0065
Giardia lamblia Kinase, CMGC CK2 0.0833 1 0.5
Echinococcus multilocularis muscleblind protein 0.0146 0.1443 0.1386
Schistosoma mansoni protein kinase 0.0833 1 1
Onchocerca volvulus 0.0791 0.9475 1
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Echinococcus multilocularis neuropeptide s receptor 0.0448 0.5206 0.5174
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0538 0.0475
Echinococcus granulosus survival motor neuron protein 1 0.0466 0.5431 0.5401
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0079 0.0609 0.0547
Loa Loa (eye worm) inositol-1 0.0073 0.0538 0.0475
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.1325 0.1267
Brugia malayi Latrophilin receptor protein 2 0.0046 0.021 0.0145
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0079 0.0609 0.0547
Loa Loa (eye worm) hypothetical protein 0.01 0.0881 0.082
Loa Loa (eye worm) hypothetical protein 0.0062 0.0408 0.0345
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0833 1 1
Schistosoma mansoni hypothetical protein 0.0289 0.3231 0.3187
Brugia malayi Muscleblind-like protein 0.0146 0.1443 0.1386
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0073 0.0538 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0046 0.021 0.0145
Trichomonas vaginalis CMGC family protein kinase 0.0833 1 1
Loa Loa (eye worm) hypothetical protein 0.0466 0.5431 0.5401
Echinococcus multilocularis GPCR, family 2 0.0046 0.021 0.0145
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0833 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0079 0.0609 0.0547
Loa Loa (eye worm) MBCTL1 0.0054 0.0306 0.0242
Loa Loa (eye worm) hypothetical protein 0.0146 0.1443 0.1386
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0079 0.0609 0.0547
Echinococcus granulosus voltage gated potassium channel 0.0079 0.0609 0.0547
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Trichomonas vaginalis adenylate cyclase, putative 0.0079 0.0609 0.0547
Trypanosoma cruzi casein kinase II, putative 0.0833 1 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0224 0.0159
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0065 0.0443 0.1612
Trichomonas vaginalis guanylate cyclase, putative 0.0079 0.0609 0.0547
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0073 0.0538 0.0538
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0079 0.0609 0.0547
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0359 0.0295
Plasmodium vivax aspartyl proteinase, putative 0.0049 0.0247 0.0183
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.0359 0.0295
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0359 0.0295
Schistosoma mansoni hypothetical protein 0.0046 0.021 0.0145
Loa Loa (eye worm) hypothetical protein 0.0044 0.0177 0.0112
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0079 0.0609 0.0547
Schistosoma mansoni microtubule-associated protein tau 0.0669 0.795 0.7937
Brugia malayi jmjC domain containing protein 0.0058 0.0359 0.0295
Loa Loa (eye worm) hypothetical protein 0.0146 0.1443 0.1386
Plasmodium vivax plasmepsin IV, putative 0.0049 0.0247 0.0183
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0538 0.0475
Schistosoma mansoni inositol monophosphatase 0.0073 0.0538 0.0475

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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