Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | protein jagged 1 | 0.0074 | 0.0778 | 0.1141 |
Echinococcus granulosus | Tolloid protein 1 | 0.0056 | 0.0347 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0157 | 0.2738 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0134 | 0.2209 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0061 | 0.0484 | 0.0709 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0464 | 1 | 0.5 |
Echinococcus multilocularis | fibropellin Ia | 0.0074 | 0.0778 | 0.1141 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0134 | 0.2209 | 0.3237 |
Echinococcus granulosus | dihydrofolate reductase | 0.0134 | 0.2209 | 0.3237 |
Brugia malayi | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Giardia lamblia | High cysteine protein | 0.0074 | 0.0778 | 0.5 |
Onchocerca volvulus | 0.0074 | 0.0778 | 0.1141 | |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.033 | 0.6823 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0061 | 0.0484 | 0.0709 |
Onchocerca volvulus | Dual oxidase homolog | 0.0061 | 0.0484 | 0.0709 |
Echinococcus multilocularis | laminin | 0.0056 | 0.0347 | 0.0508 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0061 | 0.0484 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Echinococcus multilocularis | neural cadherin | 0.0074 | 0.0778 | 0.1141 |
Echinococcus multilocularis | protein jagged 2 | 0.0074 | 0.0778 | 0.1141 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0074 | 0.0778 | 0.1141 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Onchocerca volvulus | Peroxidasin homolog | 0.0061 | 0.0484 | 0.0709 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | notch protein | 0.0074 | 0.0778 | 0.1141 |
Echinococcus granulosus | delta-like protein 1 | 0.0074 | 0.0778 | 0.1141 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | Fibulin-1 precursor | 0.0056 | 0.0347 | 0.0508 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Onchocerca volvulus | 0.0074 | 0.0778 | 0.1141 | |
Onchocerca volvulus | 0.0074 | 0.0778 | 0.1141 | |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | Delta serrate ligand family protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Onchocerca volvulus | Slit protein homolog | 0.0074 | 0.0778 | 0.1141 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0464 | 1 | 0.5 |
Brugia malayi | notch-like transmembrane receptor | 0.0074 | 0.0778 | 0.1141 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | Notch2 | 0.0074 | 0.0778 | 0.1141 |
Echinococcus granulosus | laminin | 0.0056 | 0.0347 | 0.0508 |
Brugia malayi | EGF-like domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Echinococcus granulosus | peroxidasin | 0.0061 | 0.0484 | 0.0709 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0464 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | dihydrofolate reductase family protein | 0.0134 | 0.2209 | 0.3237 |
Schistosoma mansoni | notch | 0.0074 | 0.0778 | 0.1141 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0464 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0347 | 0.0508 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0074 | 0.0778 | 0.1141 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.033 | 0.6823 | 1 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0464 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0074 | 0.0778 | 0.1141 |
Schistosoma mansoni | septate junction protein | 0.0074 | 0.0778 | 0.1141 |
Mycobacterium ulcerans | thymidylate synthase | 0.033 | 0.6823 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Onchocerca volvulus | Peroxidase homolog | 0.0061 | 0.0484 | 0.0709 |
Onchocerca volvulus | 0.0213 | 0.4056 | 0.5944 | |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0056 | 0.0347 | 0.0508 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0134 | 0.2209 | 0.3237 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Schistosoma mansoni | peroxidasin | 0.0061 | 0.0484 | 0.0709 |
Schistosoma mansoni | notch | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0347 | 0.0508 |
Echinococcus granulosus | protein jagged 1 | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0056 | 0.0347 | 0.0508 |
Brugia malayi | Animal haem peroxidase family protein | 0.0061 | 0.0484 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | hypothetical protein | 0.0157 | 0.2738 | 0.4013 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | Peroxidasin | 0.0061 | 0.0484 | 0.0709 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0134 | 0.2209 | 0.3237 |
Brugia malayi | thymidylate synthase | 0.033 | 0.6823 | 1 |
Onchocerca volvulus | 0.0061 | 0.0484 | 0.0709 | |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0056 | 0.0347 | 0.0508 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0187 | 0.3446 | 0.505 |
Echinococcus granulosus | notch | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Brugia malayi | Animal haem peroxidase family protein | 0.0061 | 0.0484 | 0.0709 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.033 | 0.6823 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Schistosoma mansoni | slit | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | Animal haem peroxidase family protein | 0.0061 | 0.0484 | 0.0709 |
Echinococcus granulosus | protein jagged 2 | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0061 | 0.0484 | 0.0709 |
Schistosoma mansoni | dihydrofolate reductase | 0.0134 | 0.2209 | 0.3237 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Echinococcus granulosus | fibropellin Ia | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | EGF-like domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0074 | 0.0778 | 0.1141 |
Schistosoma mansoni | notch | 0.0074 | 0.0778 | 0.1141 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0074 | 0.0778 | 0.1141 |
Onchocerca volvulus | 0.033 | 0.6823 | 1 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0061 | 0.0484 | 0.0709 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0056 | 0.0347 | 0.0508 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0074 | 0.0778 | 0.1141 |
Echinococcus granulosus | neural cadherin | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0056 | 0.0347 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Echinococcus granulosus | protein jagged 1 | 0.0074 | 0.0778 | 0.1141 |
Echinococcus multilocularis | peroxidasin | 0.0061 | 0.0484 | 0.0709 |
Schistosoma mansoni | notch | 0.0074 | 0.0778 | 0.1141 |
Echinococcus granulosus | thymidylate synthase | 0.033 | 0.6823 | 1 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0074 | 0.0778 | 0.0447 |
Brugia malayi | Dihydrofolate reductase | 0.0134 | 0.2209 | 0.3237 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | EGF-like domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | thymidylate synthase | 0.033 | 0.6823 | 1 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0056 | 0.0347 | 0.0508 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0074 | 0.0778 | 0.1141 |
Echinococcus granulosus | slit 2 protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Schistosoma mansoni | egf-like domain protein | 0.0056 | 0.0347 | 0.0508 |
Onchocerca volvulus | 0.0074 | 0.0778 | 0.1141 | |
Echinococcus multilocularis | protein jagged 1 | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0347 | 0.0508 |
Onchocerca volvulus | Arrow homolog | 0.0056 | 0.0347 | 0.0508 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0061 | 0.0484 | 0.0709 |
Brugia malayi | Cadherin domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Echinococcus multilocularis | fibrillin 1 | 0.0056 | 0.0347 | 0.0508 |
Brugia malayi | Animal haem peroxidase family protein | 0.0061 | 0.0484 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Echinococcus multilocularis | slit 2 protein | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Onchocerca volvulus | 0.0061 | 0.0484 | 0.0709 | |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Onchocerca volvulus | Putative cubilin | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0347 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | Muscle positioning protein 4 | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | Blistered cuticle protein 3 | 0.0061 | 0.0484 | 0.0709 |
Trichomonas vaginalis | set domain proteins, putative | 0.0213 | 0.4056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0056 | 0.0347 | 0.0508 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0074 | 0.0778 | 0.1141 |
Schistosoma mansoni | notch | 0.0074 | 0.0778 | 0.1141 |
Echinococcus multilocularis | thymidylate synthase | 0.033 | 0.6823 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0187 | 0.3446 | 0.505 |
Brugia malayi | EGF-like domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0347 | 0.0508 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0061 | 0.0484 | 0.0709 |
Onchocerca volvulus | Peroxidase homolog | 0.0061 | 0.0484 | 0.0709 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Schistosoma mansoni | peroxidasin | 0.0061 | 0.0484 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Schistosoma mansoni | cell polarity protein | 0.0074 | 0.0778 | 0.1141 |
Echinococcus multilocularis | notch | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0778 | 0.1141 |
Echinococcus granulosus | protein jagged 2 | 0.0074 | 0.0778 | 0.1141 |
Onchocerca volvulus | 0.0074 | 0.0778 | 0.1141 | |
Onchocerca volvulus | 0.0061 | 0.0484 | 0.0709 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0061 | 0.0484 | 0.0709 |
Brugia malayi | Cadherin domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0484 | 0.0709 |
Schistosoma mansoni | notch | 0.0074 | 0.0778 | 0.1141 |
Brugia malayi | EGF-like domain containing protein | 0.0074 | 0.0778 | 0.1141 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.