TDR Targets

Basic information

Technical information

TDR Targets ID: 187131
Name: N-[(2S,3S)-5-[[(2S)-1-[[(2S)-1-amino-4-methyl -1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]ami no]-1-[(4-bromophenyl)methoxy]-3-hydroxy-5-ox opentan-2-yl]-2,4,6-trifluorobenzamide
MW: 659.492 | Formula: C28H34BrF3N4O6
H donors: 5 H acceptors: 5 LogP: 2.65 Rotable bonds: 18
Rule of 5 violations (Lipinski): 2
SMILES: CC(C[C@@H](C(=O)N)NC(=O)[C@@H](NC(=O)C[C@@H]([C@@H](NC(=O)c1c(F)cc(cc1F)F)COCc1ccc(cc1)Br)O)C)C
InChi: 1S/C28H34BrF3N4O6/c1-14(2)8-21(26(33)39)35-27(40)15(3)34-24(38)11-23(37)22(13-42-12-16-4-6-17(29)7-5-16)36-28(41)25-19(31)9-18(30)10-20(25)32/h4-7,9-10,14-15,21-23,37H,8,11-13H2,1-3H3,(H2,33,39)(H,34,38)(H,35,40)(H,36,41)/t15-,21-,22-,23-/m0/s1
InChiKey: BTVFEHHDPWMSER-OBAATPRFSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

N-[(1S,2S)-1-[(4-bromophenyl)methoxymethyl]-4-[[(1S)-2-[[(1S)-1-carbamoyl-3-methyl-butyl]amino]-1-methyl-2-oxo-ethyl]amino]-2-hydroxy-4-oxo-butyl]-2,4,6-trifluoro-benzamide
N-[(1S,2S)-1-[(4-bromophenyl)methoxymethyl]-4-[[(1S)-2-[[(1S)-1-carbamoyl-3-methylbutyl]amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-4-oxobutyl]-2,4,6-trifluorobenzamide
N-[(2S,3S)-5-[[(2S)-1-[[(2S)-1-azanyl-4-methyl-1-oxo-pentan-2-yl]amino]-1-oxo-propan-2-yl]amino]-1-[(4-bromophenyl)methoxy]-3-hydroxy-5-oxo-pentan-2-yl]-2,4,6-trifluoro-benzamide
N-[(1S,2S)-1-[(4-bromobenzyl)oxymethyl]-4-[[(1S)-2-[[(1S)-1-carbamoyl-3-methyl-butyl]amino]-2-keto-1-methyl-ethyl]amino]-2-hydroxy-4-keto-butyl]-2,4,6-trifluoro-benzamide
N-[(2S,3S)-5-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxo-pentan-2-yl]amino]-1-oxo-propan-2-yl]amino]-1-[(4-bromophenyl)methoxy]-3-hydroxy-5-oxo-pentan-2-yl]-2,4,6-trifluoro-benzamide
Statine-like inhibitor 27

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	cathepsin D	Starlite/ChEMBL	References
Plasmodium falciparum	plasmepsin I	Starlite/ChEMBL	References
Plasmodium falciparum	plasmepsin II	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Plasmodium falciparum	plasmepsin IV	Get druggable targets OG5_126885	All targets in OG5_126885
Theileria parva	pepsinogen, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium yoelii	plasmepsin	Get druggable targets OG5_126885	All targets in OG5_126885
Schistosoma mansoni	cathepsin D (A01 family)	Get druggable targets OG5_126885	All targets in OG5_126885
Trichomonas vaginalis	Clan AA, family A1, cathepsin D-like aspartic peptidase	Get druggable targets OG5_126885	All targets in OG5_126885
Toxoplasma gondii	aspartyl proteinase (eimepsin), putative	Get druggable targets OG5_126885	All targets in OG5_126885
Babesia bovis	eukaryotic aspartyl protease family protein	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium berghei	plasmepsin VI	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium yoelii	hypothetical protein	Get druggable targets OG5_126885	All targets in OG5_126885
Echinococcus multilocularis	cathepsin d (lysosomal aspartyl protease)	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium vivax	aspartyl proteinase, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Candida albicans	vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C)	Get druggable targets OG5_126885	All targets in OG5_126885
Cryptosporidium hominis	aspartyl protease precursor	Get druggable targets OG5_126885	All targets in OG5_126885
Candida albicans	vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C)	Get druggable targets OG5_126885	All targets in OG5_126885
Loa Loa (eye worm)	aspartic protease BmAsp-2	Get druggable targets OG5_126885	All targets in OG5_126885
Cryptosporidium parvum	membrane bound aspartyl proteinase with a signal peptide plus transmembrane domain	Get druggable targets OG5_126885	All targets in OG5_126885
Schistosoma japonicum	ko:K01379 cathepsin D [EC3.4.23.5], putative	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium berghei	plasmepsin IV	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium vivax	plasmepsin IV, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Neospora caninum	Pepsinogen A1, related	Get druggable targets OG5_126885	All targets in OG5_126885
Neospora caninum	Renin, related	Get druggable targets OG5_126885	All targets in OG5_126885
Schistosoma japonicum	Cathepsin D precursor, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium falciparum	plasmepsin II	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium knowlesi	aspartyl protease, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium yoelii	hypothetical protein	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium falciparum	plasmepsin I	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium knowlesi	plasmepsin IV, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Schistosoma mansoni	cathepsin D (A01 family)	Get druggable targets OG5_126885	All targets in OG5_126885
Toxoplasma gondii	aspartyl protease ASP1	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium falciparum	plasmepsin VI	Get druggable targets OG5_126885	All targets in OG5_126885
Theileria parva	cathepsin E, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126885	All targets in OG5_126885
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	Get druggable targets OG5_126885	All targets in OG5_126885
Echinococcus granulosus	cathepsin d lysosomal aspartyl protease	Get druggable targets OG5_126885	All targets in OG5_126885

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Plasmodium falciparum	plasmepsin X	cathepsin D	412 aa	339 aa	28.9 %
Plasmodium vivax	aspartyl protease, putative	plasmepsin I	452 aa	368 aa	26.1 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	regulator of G protein signaling 7	0.0009	0.0068	0.0068
Loa Loa (eye worm)	aspartic protease BmAsp-2	0.0236	0.5783	0.5783
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0056	0.1239	0.1239
Brugia malayi	hypothetical protein	0.0009	0.0068	0.0068
Schistosoma mansoni	tar DNA-binding protein	0.0067	0.1511	0.1511
Loa Loa (eye worm)	aspartyl protease 6	0.0056	0.1239	0.1239
Trypanosoma cruzi	guanine nucleotide releasing protein, putative	0.0007	0	0.5
Loa Loa (eye worm)	STE/STE20/TAO protein kinase	0.0403	1	1
Schistosoma mansoni	serine/threonine protein kinase	0.0403	1	1
Loa Loa (eye worm)	hypothetical protein	0.019	0.4615	0.4615
Echinococcus granulosus	serine:threonine protein kinase TAO1	0.0403	1	1
Brugia malayi	Serine/threonine-protein kinase SULU	0.0403	1	1
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0068	0.0068
Brugia malayi	Latrophilin receptor protein 2	0.0017	0.025	0.025
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Plasmodium falciparum	plasmepsin VI	0.0236	0.5783	1
Loa Loa (eye worm)	TAR-binding protein	0.0067	0.1511	0.1511
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0067	0.1511	0.1511
Schistosoma mansoni	dishevelled	0.0009	0.0068	0.0068
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0017	0.025	0.025
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0056	0.1239	0.1239
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.0009	0.0068	0.0068
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Plasmodium falciparum	plasmepsin I	0.0236	0.5783	1
Loa Loa (eye worm)	DIX domain-containing protein	0.0009	0.0068	0.0068
Toxoplasma gondii	eukaryotic aspartyl protease superfamily protein	0.0056	0.1239	0.205
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Echinococcus multilocularis	segment polarity protein dishevelled	0.0009	0.0068	0.0068
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0056	0.1239	0.1239
Onchocerca volvulus		0.0009	0.0068	0.0146
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0056	0.1239	0.1239
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0056	0.1239	0.1239
Brugia malayi	Pepsin A precursor	0.0056	0.1239	0.1239
Echinococcus multilocularis	regulator of G protein signaling 7	0.0009	0.0068	0.0068
Brugia malayi	Domain found in Dishevelled, Egl-10, and Pleckstrin family protein	0.0009	0.0068	0.0068
Loa Loa (eye worm)	aspartic protease BmAsp-1	0.0056	0.1239	0.1239
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0017	0.025	0.025
Loa Loa (eye worm)	hypothetical protein	0.0052	0.1153	0.1153
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0068	0.0068
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0017	0.025	0.025
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Schistosoma mansoni	z-protein (S1r protein)	0.0009	0.0068	0.0068
Schistosoma mansoni	tar DNA-binding protein	0.0067	0.1511	0.1511
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0017	0.025	0.025
Schistosoma mansoni	tar DNA-binding protein	0.0067	0.1511	0.1511
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Brugia malayi	latrophilin 2 splice variant baaae	0.0036	0.0735	0.0735
Schistosoma mansoni	tar DNA-binding protein	0.0067	0.1511	0.1511
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0056	0.1239	0.1239
Trypanosoma cruzi	hypothetical protein	0.0007	0	0.5
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0056	0.1239	0.1239
Echinococcus granulosus	segment polarity protein dishevelled	0.0009	0.0068	0.0068
Echinococcus granulosus	tar DNA binding protein	0.0067	0.1511	0.1511
Schistosoma mansoni	hypothetical protein	0.0036	0.0735	0.0735
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0017	0.025	0.025
Brugia malayi	Eukaryotic aspartyl protease family protein	0.0056	0.1239	0.1239
Brugia malayi	DIX domain containing protein	0.0009	0.0068	0.0068
Loa Loa (eye worm)	hypothetical protein	0.0236	0.5783	0.5783
Brugia malayi	RNA recognition motif domain containing protein	0.0067	0.1511	0.1511
Brugia malayi	hypothetical protein	0.0009	0.0068	0.0068
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Echinococcus granulosus	cathepsin d lysosomal aspartyl protease	0.0236	0.5783	0.5783
Brugia malayi	hypothetical protein	0.0056	0.1239	0.1239
Plasmodium vivax	aspartyl proteinase, putative	0.0236	0.5783	1
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0068	0.0068
Brugia malayi	aspartic protease BmAsp-2, identical	0.0056	0.1239	0.1239
Echinococcus multilocularis	serine:threonine protein kinase TAO1	0.0403	1	1
Toxoplasma gondii	aspartyl protease ASP1	0.0236	0.5783	1
Brugia malayi	Domain found in Dishevelled, Egl-10, and Pleckstrin family protein	0.0009	0.0068	0.0068
Schistosoma mansoni	cathepsin D (A01 family)	0.0351	0.8682	0.8682
Loa Loa (eye worm)	hypothetical protein	0.0056	0.1239	0.1239
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0052	0.1153	0.1153
Loa Loa (eye worm)	RNA binding protein	0.0067	0.1511	0.1511
Brugia malayi	N-terminal motif family protein	0.019	0.4615	0.4615
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Schistosoma mansoni	cathepsin D (A01 family)	0.0351	0.8682	0.8682
Schistosoma mansoni	hypothetical protein	0.0017	0.025	0.025
Echinococcus granulosus	Pleckstrin G protein interacting region	0.0009	0.0068	0.0068
Toxoplasma gondii	aspartyl protease	0.0056	0.1239	0.205
Echinococcus multilocularis	segment polarity protein dishevelled	0.0009	0.0068	0.0068
Brugia malayi	TAR-binding protein	0.0067	0.1511	0.1511
Onchocerca volvulus		0.0056	0.1239	0.2685
Schistosoma mansoni	hypothetical protein	0.0017	0.025	0.025
Schistosoma mansoni	memapsin-2 (A01 family)	0.0056	0.1239	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0017	0.025	0.025
Plasmodium falciparum	plasmepsin IV	0.0236	0.5783	1
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0056	0.1239	0.1239
Schistosoma mansoni	dep domain containing protein	0.0009	0.0068	0.0068
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0017	0.025	0.025
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0052	0.1153	0.1153
Echinococcus granulosus	segment polarity protein dishevelled	0.0009	0.0068	0.0068
Schistosoma mansoni	hypothetical protein	0.0017	0.025	0.025
Entamoeba histolytica	hypothetical protein	0.0007	0	0.5
Echinococcus granulosus	GPCR family 2	0.0017	0.025	0.025
Echinococcus granulosus	regulator of G protein signaling 7	0.0009	0.0068	0.0068
Echinococcus multilocularis	cathepsin d (lysosomal aspartyl protease)	0.0236	0.5783	0.5783
Echinococcus multilocularis	GPCR, family 2	0.0017	0.025	0.025
Schistosoma mansoni	regulator of G protein signaling	0.0009	0.0068	0.0068
Trichomonas vaginalis	Clan AA, family A1, cathepsin D-like aspartic peptidase	0.0236	0.5783	1
Schistosoma mansoni	hypothetical protein	0.0017	0.025	0.025
Toxoplasma gondii	aspartyl proteinase (eimepsin), putative	0.0236	0.5783	1
Brugia malayi	regulator of G-protein signaling egl-10	0.0009	0.0068	0.0068
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Brugia malayi	hypothetical protein	0.0056	0.1239	0.1239
Echinococcus multilocularis	Pleckstrin G protein, interacting region	0.0009	0.0068	0.0068
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0735	0.0735
Onchocerca volvulus	Segment polarity protein dishevelled homolog	0.0009	0.0068	0.0146
Schistosoma mansoni	dishevelled	0.0009	0.0068	0.0068
Echinococcus multilocularis	regulator of G protein signaling 7	0.0009	0.0068	0.0068
Toxoplasma gondii	aspartyl protease ASP3	0.0056	0.1239	0.205
Brugia malayi	aspartic protease BmAsp-1, identical	0.0056	0.1239	0.1239
Plasmodium vivax	plasmepsin IV, putative	0.0236	0.5783	1
Echinococcus multilocularis	tar DNA binding protein	0.0067	0.1511	0.1511
Brugia malayi	RNA binding protein	0.0067	0.1511	0.1511
Plasmodium falciparum	plasmepsin II	0.0236	0.5783	1
Onchocerca volvulus	Rap guanine nucleotide exchange factor 1 homolog	0.019	0.4615	1
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0052	0.1153	0.1153
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0056	0.1239	0.1239
Onchocerca volvulus		0.0056	0.1239	0.2685
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0236	0.5783	0.5783
Schistosoma mansoni	fyve finger-containing phosphoinositide kinase fyv1	0.0009	0.0068	0.0068
Schistosoma mansoni	tar DNA-binding protein	0.0067	0.1511	0.1511
Trypanosoma cruzi	hypothetical protein	0.0007	0	0.5
Entamoeba histolytica	Ras guanine nucleotide exchange factor, putative	0.0007	0	0.5

Activities

Activity type	Activity value	Assay description	Source	Reference
Inhibition (functional)	= 10 %	Inhibition of Plasmodium falciparum growth in infected human red blood cells (RBC) at concentration of 5 microM	ChEMBL.	15189032
Inhibition (functional)	= 10 %	Percentage inhibition of parasite growth in human red blood cells at an inhibitor concentration of 5 uM	ChEMBL.	15974592
Inhibition (functional)	= 10 %	Inhibition of Plasmodium falciparum growth in infected human red blood cells (RBC) at concentration of 5 microM	ChEMBL.	15189032
Inhibition (functional)	= 10 %	Percentage inhibition of parasite growth in human red blood cells at an inhibitor concentration of 5 uM	ChEMBL.	15974592
Ki (binding)	= 3.4 nM	In vitro inhibition of aspartic protease plasmepsin (Plm) I of Plasmodium falciparum.	ChEMBL.	15189032
Ki (binding)	= 3.4 nM	Inhibitory concentration against the Plasmepsin I of Plasmodium falciparum	ChEMBL.	15974592
Ki (binding)	= 3.4 nM	In vitro inhibition of aspartic protease plasmepsin (Plm) I of Plasmodium falciparum.	ChEMBL.	15189032
Ki (binding)	= 3.4 nM	Inhibitory concentration against the Plasmepsin I of Plasmodium falciparum	ChEMBL.	15974592
Ki (binding)	= 10 nM	In vitro inhibition of aspartic protease plasmepsin (Plm) II of Plasmodium falciparum	ChEMBL.	15189032
Ki (binding)	= 10 nM	Inhibitory concentration against the Plasmepsin II of Plasmodium falciparum	ChEMBL.	15974592
Ki (binding)	= 10 nM	In vitro inhibition of aspartic protease plasmepsin (Plm) II of Plasmodium falciparum	ChEMBL.	15189032
Ki (binding)	= 10 nM	Inhibitory concentration against the Plasmepsin II of Plasmodium falciparum	ChEMBL.	15974592
Ki (binding)	> 4000 nM	In vitro inhibition of human liver cathepsin D.	ChEMBL.	15189032
Ki (binding)	> 4000 nM	Inhibitory concentration against the human Cathepsin D	ChEMBL.	15974592
Ki (binding)	> 4000 nM	In vitro inhibition of human liver cathepsin D.	ChEMBL.	15189032
Ki (binding)	> 4000 nM	Inhibitory concentration against the human Cathepsin D	ChEMBL.	15974592

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL113331
PubChem: 6539232

Bibliographic References

2 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 187131