Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0119 | 0.3398 | 0.3398 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0119 | 0.3398 | 0.3033 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0119 | 0.3398 | 0.3033 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0119 | 0.3398 | 1 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0326 | 1 | 1 |
Plasmodium falciparum | polyprenol reductase, putative | 0.0119 | 0.3398 | 0.5 |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.0119 | 0.3398 | 1 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0119 | 0.3398 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0119 | 0.3398 | 0.3033 |
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0119 | 0.3398 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.3398 | 0.3033 |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0029 | 0.0523 | 0.154 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0119 | 0.3398 | 0.3033 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.0326 | 1 | 1 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.0119 | 0.3398 | 0.3033 |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.0119 | 0.3398 | 1 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.0326 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0119 | 0.3398 | 0.3033 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.3398 | 0.3033 |
Entamoeba histolytica | 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein | 0.0119 | 0.3398 | 0.3033 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0326 | 1 | 1 |
Entamoeba histolytica | trans-2,3-enoyl-CoA reductase, putative | 0.0119 | 0.3398 | 0.3033 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.0119 | 0.3398 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0326 | 1 | 1 |
Trypanosoma brucei | CAAX amino terminal protease, putative | 0.0029 | 0.0523 | 0.0523 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.0119 | 0.3398 | 1 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0119 | 0.3398 | 0.3033 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.0119 | 0.3398 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0326 | 1 | 1 |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0029 | 0.0523 | 0.154 |
Onchocerca volvulus | 0.0119 | 0.3398 | 0.5 | |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0326 | 1 | 1 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.0326 | 1 | 1 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0326 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0326 | 1 | 1 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0119 | 0.3398 | 0.5 |
Plasmodium vivax | polyprenol reductase, putative | 0.0119 | 0.3398 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0119 | 0.3398 | 0.3033 |
Mycobacterium ulcerans | hypothetical protein | 0.0326 | 1 | 0.5 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0119 | 0.3398 | 0.3033 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.