Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Blistered cuticle protein 3 | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0324 | 0.3093 | 0.1668 |
Brugia malayi | EGF-like domain containing protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Brugia malayi | GCC2 and GCC3 family protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Echinococcus granulosus | 3-phosphoinositide-dependent protein kinase 1 | 0.0324 | 0.3093 | 0.1668 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.019 | 0.1711 | 0.1711 |
Brugia malayi | EGF-like domain containing protein | 0.019 | 0.1711 | 0.1711 |
Brugia malayi | phosphoinositide-dependent protein kinase I | 0.0324 | 0.3093 | 0.3093 |
Onchocerca volvulus | 0.0993 | 1 | 1 | |
Onchocerca volvulus | Peroxidasin homolog | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | Notch2 | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Brugia malayi | notch-like transmembrane receptor | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Trichomonas vaginalis | AGC family protein kinase | 0.0324 | 0.3093 | 0.5 |
Brugia malayi | Delta serrate ligand family protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Brugia malayi | Animal haem peroxidase family protein | 0.0993 | 1 | 1 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.019 | 0.1711 | 0.1711 |
Brugia malayi | Animal haem peroxidase family protein | 0.0993 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Brugia malayi | EGF-like domain containing protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0993 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0324 | 0.3093 | 0.3093 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Onchocerca volvulus | 0.0993 | 1 | 1 | |
Loa Loa (eye worm) | notch protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Brugia malayi | EGF-like domain containing protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.0324 | 0.3093 | 0.3093 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.019 | 0.1711 | 0.1711 |
Onchocerca volvulus | 0.0993 | 1 | 1 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.0324 | 0.3093 | 0.3093 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Schistosoma mansoni | peroxidasin | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0993 | 1 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Giardia lamblia | High cysteine protein | 0.019 | 0.1711 | 0.5 |
Brugia malayi | Muscle positioning protein 4 | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0993 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0324 | 0.3093 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0324 | 0.3093 | 0.5 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Brugia malayi | EGF-like domain containing protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0993 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0993 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0993 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Trichomonas vaginalis | AGC family protein kinase | 0.0324 | 0.3093 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Brugia malayi | Peroxidasin | 0.0993 | 1 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0993 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Echinococcus multilocularis | 3 phosphoinositide dependent protein kinase 1 | 0.0324 | 0.3093 | 0.1668 |
Toxoplasma gondii | EGF family domain-containing protein | 0.019 | 0.1711 | 0.5 |
Onchocerca volvulus | Dual oxidase homolog | 0.0993 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0993 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1711 | 0.1711 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.