Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | hypothetical protein, conserved | 0.0164 | 0.0036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0233 | 0.0397 |
Echinococcus multilocularis | beta galactosidase | 0.0874 | 0.2092 | 0.2064 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0955 | 0.2329 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0874 | 0.2092 | 0.3563 |
Onchocerca volvulus | 0.0232 | 0.0233 | 0.0693 | |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0164 | 0.0036 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0164 | 0.0036 | 0.5 |
Onchocerca volvulus | Trehalase homolog | 0.0232 | 0.0233 | 0.0693 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0233 | 0.0397 |
Trypanosoma brucei | glycosyl hydrolase-like protein | 0.0164 | 0.0036 | 0.5 |
Brugia malayi | Trehalase family protein | 0.0232 | 0.0233 | 0.0339 |
Onchocerca volvulus | 0.0232 | 0.0233 | 0.0693 | |
Brugia malayi | Trehalase family protein | 0.0232 | 0.0233 | 0.0339 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.171 | 0.4516 | 0.7676 |
Schistosoma mansoni | alpha-glucosidase | 0.171 | 0.4516 | 0.7676 |
Brugia malayi | Trehalase family protein | 0.0232 | 0.0233 | 0.0339 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0164 | 0.0036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0874 | 0.2092 | 0.3563 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0036 | 0.0061 |
Schistosoma mansoni | alpha-l-fucosidase | 0.2177 | 0.5872 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0267 | 0.0334 | 0.5 |
Onchocerca volvulus | 0.1149 | 0.289 | 1 | |
Leishmania major | glycosyl hydrolase-like protein | 0.0164 | 0.0036 | 0.5 |
Brugia malayi | hypothetical protein | 0.0232 | 0.0233 | 0.0339 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.2177 | 0.5872 | 1 |
Schistosoma mansoni | beta-galactosidase | 0.0874 | 0.2092 | 0.3524 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0164 | 0.0036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0233 | 0.0397 |
Loa Loa (eye worm) | trehalase | 0.0232 | 0.0233 | 0.0397 |
Loa Loa (eye worm) | trehalase | 0.0232 | 0.0233 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0233 | 0.0397 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0164 | 0.0036 | 0.5 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.3601 | 1 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0164 | 0.0036 | 0.0061 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0164 | 0.0036 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.171 | 0.4516 | 0.7676 |
Loa Loa (eye worm) | trehalase | 0.0232 | 0.0233 | 0.0397 |
Onchocerca volvulus | 0.0232 | 0.0233 | 0.0693 | |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.3601 | 1 | 0.5 |
Loa Loa (eye worm) | TRE-1 protein | 0.0232 | 0.0233 | 0.0397 |
Onchocerca volvulus | 0.0232 | 0.0233 | 0.0693 | |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0233 | 0.0397 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0164 | 0.0036 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.171 | 0.4516 | 0.4496 |
Trichomonas vaginalis | trehalase, putative | 0.0232 | 0.0233 | 0.0862 |
Onchocerca volvulus | 0.0232 | 0.0233 | 0.0693 | |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.2177 | 0.5872 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.171 | 0.4516 | 0.4496 |
Echinococcus granulosus | beta galactosidase | 0.0874 | 0.2092 | 0.2064 |
Trypanosoma brucei | glucosidase, putative | 0.0164 | 0.0036 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.171 | 0.4516 | 0.4496 |
Plasmodium vivax | hypothetical protein, conserved | 0.0267 | 0.0334 | 0.5 |
Brugia malayi | Trehalase family protein | 0.0232 | 0.0233 | 0.0339 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0164 | 0.0036 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0232 | 0.0233 | 0.0862 |
Loa Loa (eye worm) | TRE-2 protein | 0.0232 | 0.0233 | 0.0397 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0955 | 0.2329 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.171 | 0.4516 | 0.769 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.