Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | alpha-mannosidase | 0.017 | 0.0809 | 0.5 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0138 | 0.0467 | 0.5768 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0618 | 0.5631 | 1 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Trypanosoma brucei | lysosomal alpha-mannosidase precursor, putative | 0.0151 | 0.0613 | 1 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Schistosoma mansoni | alpha-glucosidase | 0.056 | 0.5009 | 1 |
Echinococcus multilocularis | transfer RNA-Trp | 0.0114 | 0.0207 | 0.0121 |
Loa Loa (eye worm) | glycosyl hydrolase family 38 protein | 0.017 | 0.0809 | 0.1378 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Schistosoma mansoni | mannosyl-oligosaccharide alpha-12-mannosidase | 0.0114 | 0.0207 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0207 | 0.0302 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0138 | 0.0467 | 0.5768 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0138 | 0.0467 | 0.0594 |
Schistosoma mansoni | lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) | 0.0151 | 0.0613 | 0.097 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0618 | 0.5631 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0207 | 0.0302 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0114 | 0.0207 | 0.2561 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Echinococcus granulosus | lysosomal alpha mannosidase | 0.0151 | 0.0613 | 0.0748 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0138 | 0.0467 | 0.5768 |
Echinococcus multilocularis | lysosomal alpha mannosidase | 0.0151 | 0.0613 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0196 | 0.0281 |
Trypanosoma cruzi | lysosomal alpha-mannosidase precursor, putative | 0.0151 | 0.0613 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0138 | 0.0467 | 0.0766 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0141 | 0.0183 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0138 | 0.0467 | 0.0479 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0138 | 0.0467 | 0.5768 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0138 | 0.0467 | 0.5768 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Trypanosoma brucei | glucosidase, putative | 0.0138 | 0.0467 | 0.5788 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0141 | 0.0183 |
Onchocerca volvulus | 0.056 | 0.5009 | 1 | |
Loa Loa (eye worm) | mannosidase | 0.0114 | 0.0207 | 0.0302 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0138 | 0.0467 | 0.0594 |
Trichomonas vaginalis | alpha-mannosidase, putative | 0.017 | 0.0809 | 1 |
Brugia malayi | Glycosyl hydrolases family 38 protein | 0.017 | 0.0809 | 0.1217 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0138 | 0.0467 | 0.5768 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Brugia malayi | Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform 1 | 0.0114 | 0.0207 | 0.0121 |
Trichomonas vaginalis | alpha-mannosidase 2c1, putative | 0.0101 | 0.007 | 0.0865 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Echinococcus multilocularis | mannosyl oligosaccharide 1,2 alpha mannosidase | 0.0114 | 0.0207 | 0.0121 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0618 | 0.5631 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0138 | 0.0467 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.056 | 0.5009 | 1 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0138 | 0.0467 | 0.5768 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0138 | 0.0467 | 0.5768 |
Mycobacterium tuberculosis | Possible conserved exported protein | 0.1024 | 1 | 0.5 |
Trypanosoma cruzi | lysosomal alpha-mannosidase precursor, putative | 0.0151 | 0.0613 | 1 |
Trichomonas vaginalis | alpha-mannosidase 2c1, putative | 0.017 | 0.0809 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0618 | 0.5631 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0138 | 0.0467 | 0.5 |
Echinococcus multilocularis | endoplasmic reticulum mannosyl oligosaccharide | 0.0114 | 0.0207 | 0.0121 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0114 | 0.0207 | 0.2561 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0618 | 0.5631 | 1 |
Schistosoma mansoni | alpha glucosidase | 0.0138 | 0.0467 | 0.0669 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0138 | 0.0467 | 0.5768 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.