Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Dual specificity protein kinase TTK homolog | 0.0554 | 0.8948 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0087 | 0.0515 |
Schistosoma mansoni | rab6-interacting | 0.0103 | 0.1344 | 0.1344 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0103 | 0.1344 | 0.1312 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0616 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0955 | 0.1068 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0066 | 0.0713 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0066 | 0.0713 | 0.0679 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1344 | 0.1502 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.0499 | 0.8021 | 0.8021 |
Brugia malayi | hypothetical protein | 0.0103 | 0.1344 | 0.1484 |
Schistosoma mansoni | rab6-interacting | 0.0103 | 0.1344 | 0.1344 |
Schistosoma mansoni | protein kinase | 0.0066 | 0.0713 | 0.0713 |
Loa Loa (eye worm) | TTK protein kinase | 0.0554 | 0.8948 | 1 |
Onchocerca volvulus | 0.0103 | 0.1344 | 0.1484 | |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0103 | 0.1344 | 0.1312 |
Loa Loa (eye worm) | AUR protein kinase | 0.0066 | 0.0713 | 0.0796 |
Toxoplasma gondii | MAPEG family protein | 0.0114 | 0.1535 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0087 | 0.0097 |
Echinococcus granulosus | RUN | 0.0103 | 0.1344 | 0.1312 |
Leishmania major | protein kinase, putative | 0.0066 | 0.0713 | 1 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0103 | 0.1344 | 0.1312 |
Echinococcus granulosus | microsomal glutathione S transferase 3 | 0.0114 | 0.1535 | 0.1504 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0087 | 0.0515 |
Entamoeba histolytica | protein kinase , putative | 0.0066 | 0.0713 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0292 | 0.0256 |
Entamoeba histolytica | protein kinase, putative | 0.0066 | 0.0713 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0067 | 0.0745 | 0.0711 |
Loa Loa (eye worm) | doublecortin family protein | 0.0103 | 0.1344 | 0.1502 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0087 | 0.045 |
Echinococcus granulosus | dual specificity serine:threonine tyrosine | 0.0554 | 0.8948 | 0.8944 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0066 | 0.0713 | 0.5234 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0019 | 0.0021 |
Loa Loa (eye worm) | AUR protein kinase | 0.0066 | 0.0713 | 0.0796 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.0114 | 0.1535 | 0.1504 |
Brugia malayi | Protein kinase domain containing protein | 0.0554 | 0.8948 | 1 |
Echinococcus multilocularis | dual specificity serine:threonine tyrosine | 0.0554 | 0.8948 | 0.8944 |
Echinococcus multilocularis | RUN | 0.0103 | 0.1344 | 0.1312 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0087 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0383 | 0.0428 |
Giardia lamblia | Kinase, TTK | 0.0554 | 0.8948 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0085 | 0.1037 | 0.114 |
Echinococcus granulosus | aurora kinase A | 0.0066 | 0.0713 | 0.0679 |
Toxoplasma gondii | aurora kinase | 0.0066 | 0.0713 | 0.4576 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0554 | 0.8948 | 1 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0103 | 0.1344 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0713 | 0.0777 |
Schistosoma mansoni | hypothetical protein | 0.0103 | 0.1344 | 0.1344 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0554 | 0.8948 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0087 | 0.0515 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0066 | 0.0713 | 0.5234 |
Brugia malayi | hypothetical protein | 0.0103 | 0.1344 | 0.1484 |
Schistosoma mansoni | lipoxygenase | 0.0616 | 1 | 1 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0066 | 0.0713 | 1 |
Brugia malayi | hypothetical protein | 0.0348 | 0.548 | 0.6115 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0103 | 0.1344 | 0.1312 |
Loa Loa (eye worm) | AUR protein kinase | 0.0066 | 0.0713 | 0.0796 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0713 | 0.0713 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0036 | 0.0036 |
Entamoeba histolytica | protein kinase, putative | 0.0066 | 0.0713 | 0.5 |
Echinococcus multilocularis | aurora kinase A | 0.0066 | 0.0713 | 0.0679 |
Onchocerca volvulus | 0.0103 | 0.1344 | 0.1484 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0338 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1344 | 0.1502 |
Brugia malayi | Doublecortin family protein | 0.0103 | 0.1344 | 0.1484 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0082 | 0.007 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0713 | 0.0777 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0066 | 0.0713 | 0.0777 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0066 | 0.0713 | 0.0777 |
Loa Loa (eye worm) | hypothetical protein | 0.0348 | 0.548 | 0.6124 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0713 | 0.0777 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0713 | 0.0777 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0066 | 0.0713 | 0.5 |
Brugia malayi | serine/threonine kinase 12 | 0.0066 | 0.0713 | 0.0777 |
Trypanosoma brucei | aurora B kinase | 0.0066 | 0.0713 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0103 | 0.1344 | 0.1312 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0066 | 0.0713 | 0.5 |
Schistosoma mansoni | loxhd1 | 0.0103 | 0.1344 | 0.1344 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0103 | 0.1344 | 0.1312 |
Schistosoma mansoni | dual specificity serine/threonine tyrosine kinase | 0.0554 | 0.8948 | 0.8948 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.0114 | 0.1535 | 0.1535 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0066 | 0.0713 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.042 | 0.0469 |
Brugia malayi | Bromodomain containing protein | 0.0043 | 0.0337 | 0.0356 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0067 | 0.0745 | 0.0711 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0292 | 0.0256 |
Schistosoma mansoni | lipoxygenase | 0.0431 | 0.6872 | 0.6872 |
Schistosoma mansoni | polycystin 1-related | 0.0103 | 0.1344 | 0.1344 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0066 | 0.0713 | 0.0679 |
Schistosoma mansoni | bromodomain containing protein | 0.0072 | 0.0813 | 0.0813 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0103 | 0.1344 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.