TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 298.247 | Formula: C16H10O6
H donors: 3 H acceptors: 5 LogP: 2.41 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: O=C1/C(=C\c2ccc(cc2)C(=O)O)/Oc2c1ccc(c2O)O
InChi: 1S/C16H10O6/c17-11-6-5-10-13(18)12(22-15(10)14(11)19)7-8-1-3-9(4-2-8)16(20)21/h1-7,17,19H,(H,20,21)/b12-7+
InChiKey: KPSJJDXVCYMBFL-KPKJPENVSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	potassium channel subfamily K 8	0.0126	0.0367	0.0367
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0048	0.0095	0.2588
Echinococcus multilocularis	acetylcholinesterase	0.0435	0.1446	0.1446
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0435	0.1446	0.1446
Brugia malayi	hypothetical protein	0.0022	0.0002	0.0013
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0022	0.0002	0.0002
Plasmodium vivax	potassium channel, putative	0.0126	0.0367	0.9881
Brugia malayi	hypothetical protein	0.0126	0.0367	0.1963
Echinococcus multilocularis	twik family of potassium channels	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Echinococcus granulosus	G protein coupled receptor 139	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Brugia malayi	Carboxylesterase family protein	0.0073	0.0182	0.0976
Mycobacterium leprae	PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO)	0.0048	0.0095	0.5
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Mycobacterium ulcerans	flavin-containing monoamine oxidase AofH	0.0688	0.2333	1
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	BC026374 protein (S09 family)	0.0073	0.0182	0.0182
Schistosoma mansoni	hypothetical protein	0.0022	0.0002	0.0002
Leishmania major	cathepsin L-like protease	0.0069	0.0167	0.2648
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0022	0.0002	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	fmrfamide receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	lysine specific demethylase 5A	0.0064	0.0148	0.0148
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Brugia malayi	SWIRM domain containing protein	0.0048	0.0095	0.0508
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 28	0.0126	0.0367	0.1963
Echinococcus granulosus	g protein coupled receptor	0.0022	0.0002	0.0002
Brugia malayi	Serotonin receptor	0.0022	0.0002	0.0013
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0126	0.0367	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0069	0.0167	0.2648
Mycobacterium ulcerans	transmembrane cation transporter	0.0126	0.0367	0.1214
Schistosoma mansoni	opsin-like receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0095	0.0095
Brugia malayi	Choline/ethanolamine kinase family protein	0.0127	0.0371	0.1987
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0022	0.0002	0.0002
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0022	0.0002	0.0002
Loa Loa (eye worm)	acetylcholinesterase 1	0.0435	0.1446	0.1446
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Brugia malayi	hypothetical protein	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Brugia malayi	neuropeptide F receptor	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0163	0.0496	0.0496
Echinococcus granulosus	serotonin receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	neuropeptide receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	twik family of potassium channels-related	0.0126	0.0367	0.0367
Echinococcus multilocularis	Two pore potassium channel protein sup 9	0.0126	0.0367	0.0367
Onchocerca volvulus		0.0022	0.0002	0.0067
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0022	0.0002	0.0013
Brugia malayi	sulfakinin receptor protein	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus granulosus	tm gpcr rhodopsin	0.0022	0.0002	0.0002
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0022	0.0002	0.0002
Echinococcus granulosus	neuropeptides capa receptor	0.0022	0.0002	0.0002
Leishmania major	hypothetical protein, conserved	0.0126	0.0367	1
Echinococcus granulosus	hypothetical protein	0.0822	0.28	0.28
Echinococcus multilocularis	somatostatin receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	neuropeptides capa receptor	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0126	0.0367	1
Brugia malayi	neuropeptide F receptor	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.1297	0.4464	0.4464
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0064	0.0148	0.0148
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0022	0.0002	0.0002
Echinococcus granulosus	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Echinococcus multilocularis	small conductance calcium activated potassium	0.2879	1	1
Schistosoma mansoni	jumonji domain containing protein	0.0064	0.0148	0.0148
Echinococcus granulosus	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Schistosoma mansoni	growth hormone secretagogue receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	melatonin receptor type 1A	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Onchocerca volvulus		0.0073	0.0182	0.4972
Plasmodium vivax	lysine-specific histone demethylase 1, putative	0.0048	0.0095	0.2557
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	g protein coupled receptor	0.0022	0.0002	0.0002
Echinococcus granulosus	allatostatin A receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	neuropeptide Y receptor	0.0022	0.0002	0.0002
Echinococcus granulosus	biogenic amine 5HT receptor	0.0163	0.0496	0.0496
Echinococcus multilocularis	neuropeptide receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0022	0.0002	0.0002
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0022	0.0002	0.0002
Echinococcus multilocularis	neuropeptide receptor A26	0.0022	0.0002	0.0002
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0048	0.0095	0.2557
Echinococcus granulosus	tm gpcr rhodopsin	0.0022	0.0002	0.0002
Toxoplasma gondii	ion channel protein	0.0126	0.0367	0.984
Brugia malayi	G-protein coupled receptor	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	TWK-28 protein	0.0126	0.0367	0.0367
Brugia malayi	GnHR receptor homolog	0.0022	0.0002	0.0013
Echinococcus multilocularis	carboxylesterase 5A	0.0435	0.1446	0.1446
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Brugia malayi	Carboxylesterase family protein	0.0435	0.1446	0.7743
Trypanosoma cruzi	ion transport protein, putative	0.0126	0.0367	1
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Echinococcus multilocularis	potassium channel subfamily K 8	0.0126	0.0367	0.0367
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0073	0.0182	0.0182
Brugia malayi	putative neuropeptide receptor NPR1	0.0022	0.0002	0.0013
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0073	0.0182	0.0182
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Onchocerca volvulus		0.0073	0.0182	0.4972
Brugia malayi	Carboxylesterase family protein	0.0435	0.1446	0.7743
Onchocerca volvulus		0.0022	0.0002	0.0067
Brugia malayi	Carboxylesterase family protein	0.0073	0.0182	0.0976
Echinococcus granulosus	g-protein coupled receptor	0.0022	0.0002	0.0002
Plasmodium falciparum	lysine-specific histone demethylase 1, putative	0.0048	0.0095	0.2557
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Brugia malayi	hypothetical protein	0.0022	0.0002	0.0013
Echinococcus multilocularis	microtubule associated protein 2	0.0747	0.2538	0.2538
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0022	0.0002	0.0002
Echinococcus granulosus	neuropeptide receptor A26	0.0022	0.0002	0.0002
Loa Loa (eye worm)	carboxylesterase	0.0435	0.1446	0.1446
Schistosoma mansoni	amine GPCR	0.0022	0.0002	0.0002
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0022	0.0002	0.0002
Schistosoma mansoni	amine GPCR	0.0022	0.0002	0.0002
Echinococcus granulosus	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Trypanosoma cruzi	major cysteine proteinase, putative	0.0054	0.0115	0.0746
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 5	0.0126	0.0367	0.1963
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog	0.0126	0.0367	0.1963
Echinococcus granulosus	BC026374 protein S09 family	0.0073	0.0182	0.0182
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0022	0.0002	0.0002
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	calcium-activated potassium channel	0.2461	0.8537	0.8537
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0022	0.0002	0.0013
Plasmodium vivax	protoporphyrinogen oxidase, putative	0.0048	0.0095	0.2557
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 39B	0.0126	0.0367	0.1963
Echinococcus granulosus	neuropeptide Y receptor	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0073	0.0182	0.4972
Echinococcus multilocularis	g protein coupled receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0073	0.0182	0.0182
Trypanosoma brucei	calcium-activated potassium channel, putative	0.0126	0.0367	1
Echinococcus granulosus	neuropeptide receptor	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0022	0.0002	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus granulosus	orexin receptor type 2	0.0022	0.0002	0.0002
Echinococcus granulosus	neuropeptide FF receptor 2	0.0022	0.0002	0.0002
Loa Loa (eye worm)	large conductance calcium-activated potassium channel alpha subunit ai	0.0126	0.0367	0.0367
Brugia malayi	Dopamine receptor protein 2	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Echinococcus multilocularis	TWiK family of potassium channels protein 7	0.0126	0.0367	0.0367
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog	0.0126	0.0367	0.1963
Echinococcus multilocularis	neuropeptide s receptor	0.0022	0.0002	0.0002
Echinococcus granulosus	carboxylesterase 5A	0.0435	0.1446	0.1446
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0022	0.0002	0.0002
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0022	0.0002	0.0002
Schistosoma mansoni	biogenic amine receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	potassium channel subfamily K 8	0.0126	0.0367	0.0367
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Schistosoma mansoni	neuropeptide receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0022	0.0002	0.0002
Schistosoma mansoni	twik family of potassium channels-related	0.0126	0.0367	0.0367
Echinococcus granulosus	dro:myosuppressin receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	uncoordinated protein 58	0.0126	0.0367	0.0367
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0126	0.0367	1
Echinococcus granulosus	TWiK family of potassium channels protein 7	0.0126	0.0367	0.0367
Trypanosoma cruzi	ion transport protein, putative	0.0126	0.0367	1
Schistosoma mansoni	acetylcholinesterase	0.0073	0.0182	0.0182
Brugia malayi	follicle stimulating hormone receptor	0.0022	0.0002	0.0013
Schistosoma mansoni	neuropeptide receptor	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0022	0.0002	0.0067
Schistosoma mansoni	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Brugia malayi	G protein-coupled receptor	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Loa Loa (eye worm)	choline/ethanolamine kinase	0.0127	0.0371	0.0371
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	Protoporphyrinogen oxidase chloroplast/mitochondrial precursor	0.0048	0.0095	0.0095
Plasmodium vivax	hypothetical protein, conserved	0.0048	0.0095	0.2557
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 13	0.0126	0.0367	0.1963
Onchocerca volvulus		0.0073	0.0182	0.4972
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0022	0.0002	0.0002
Echinococcus multilocularis	potassium channel subfamily K	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0022	0.0002	0.0067
Schistosoma mansoni	Lysine-specific histone demethylase 1	0.0048	0.0095	0.0095
Brugia malayi	putative neuropeptide receptor	0.0022	0.0002	0.0013
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 7	0.0126	0.0367	0.1963
Brugia malayi	hypothetical protein	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Brugia malayi	G protein-coupled receptor F59B2.13	0.0022	0.0002	0.0013
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	serotonin receptor	0.0163	0.0496	0.0496
Brugia malayi	hypothetical protein	0.0022	0.0002	0.0013
Schistosoma mansoni	microtubule-associated protein tau	0.0747	0.2538	0.2538
Echinococcus granulosus	twik family of potassium channels	0.0126	0.0367	0.0367
Plasmodium falciparum	potassium channel	0.0126	0.0367	0.9881
Schistosoma mansoni	amine GPCR	0.0022	0.0002	0.0002
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus granulosus	acetylcholinesterase	0.0435	0.1446	0.1446
Trypanosoma brucei	calcium/potassium channel (CAKC), putative	0.0126	0.0367	1
Echinococcus multilocularis	serotonin receptor	0.0163	0.0496	0.0496
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0126	0.0367	1
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0022	0.0002	0.0067
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 39A	0.0126	0.0367	0.1963
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0064	0.0148	0.0148
Brugia malayi	Twik (KCNK-like) family of potasium channels, alpha subunit 40	0.0126	0.0367	0.1963
Onchocerca volvulus		0.0022	0.0002	0.0067
Echinococcus multilocularis	lysine specific histone demethylase 1A	0.0048	0.0095	0.0095
Leishmania major	ion transport protein-like protein	0.0126	0.0367	1
Echinococcus granulosus	7tm_1 domain containing protein	0.0022	0.0002	0.0002
Echinococcus multilocularis	orexin receptor type 2	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0126	0.0367	1
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	neuroligin 3 (S09 family)	0.0073	0.0182	0.0182
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0095	0.0095
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Onchocerca volvulus		0.0022	0.0002	0.0067
Echinococcus granulosus	para nitrobenzyl esterase	0.0073	0.0182	0.0182
Brugia malayi	hypothetical protein	0.0022	0.0002	0.0013
Echinococcus multilocularis	neuropeptides capa receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	opsin-like receptor	0.0022	0.0002	0.0002
Plasmodium falciparum	protoporphyrinogen oxidase	0.0048	0.0095	0.2557
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 17	0.0126	0.0367	0.1963
Schistosoma mansoni	twik family of potassium channels-related	0.0126	0.0367	0.0367
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0182	0.0182
Schistosoma mansoni	hypothetical protein	0.0022	0.0002	0.0002
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 24	0.0126	0.0367	0.1963
Brugia malayi	larval opioid receptor	0.0022	0.0002	0.0013
Mycobacterium tuberculosis	Carboxylesterase LipT	0.0073	0.0182	0.0422
Brugia malayi	Cytochrome P450 family protein	0.0049	0.0097	0.0517
Brugia malayi	G-protein coupled receptor	0.0022	0.0002	0.0013
Loa Loa (eye worm)	cytochrome P450 family protein	0.0049	0.0097	0.0097
Brugia malayi	hypothetical protein	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus granulosus	choline:ethanolamine kinase	0.0127	0.0371	0.0371
Schistosoma mansoni	amine GPCR	0.0022	0.0002	0.0002
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 45	0.0126	0.0367	0.1963
Chlamydia trachomatis	protoporphyrinogen oxidase	0.0048	0.0095	0.5
Echinococcus granulosus	calcium activated potassium channel variant	0.0126	0.0367	0.0367
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0048	0.0095	0.0095
Trypanosoma cruzi	cruzipain precursor, putative	0.0069	0.0167	0.2648
Schistosoma mansoni	amine oxidase	0.0048	0.0095	0.0095
Onchocerca volvulus		0.0022	0.0002	0.0067
Echinococcus multilocularis	neuropeptide receptor	0.0022	0.0002	0.0002
Entamoeba histolytica	calcium-gated potassium channel protein, putative	0.0126	0.0367	0.5
Loa Loa (eye worm)	potassium voltage-gated channel subfamily Q member 5	0.0126	0.0367	0.0367
Schistosoma mansoni	calcium-activated potassium channel	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0435	0.1446	0.1446
Echinococcus multilocularis	para nitrobenzyl esterase	0.0073	0.0182	0.0182
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0022	0.0002	0.0002
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0022	0.0002	0.0002
Echinococcus multilocularis	neuroligin	0.0073	0.0182	0.0182
Schistosoma mansoni	opsin-like receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0095	0.0095
Trypanosoma cruzi	cysteine peptidase, putative	0.0069	0.0167	0.2648
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 30.	0.0126	0.0367	0.1963
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0095	0.0095
Echinococcus multilocularis	g protein coupled receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	TYRA-2 protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0182	0.0182
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 32	0.0126	0.0367	0.1963
Onchocerca volvulus		0.0073	0.0182	0.4972
Echinococcus granulosus	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0095	0.0095
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	biogenic amine receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Echinococcus multilocularis	family S9 non peptidase ue (S09 family)	0.0073	0.0182	0.0182
Trypanosoma cruzi	hypothetical protein, conserved	0.0126	0.0367	1
Mycobacterium ulcerans	carboxylesterase, LipT	0.0073	0.0182	0.039
Echinococcus multilocularis	fmrfamide receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	choline:ethanolamine kinase	0.0127	0.0371	0.0371
Leishmania major	cathepsin L-like protease	0.0069	0.0167	0.2648
Echinococcus multilocularis	protoporphyrinogen oxidase	0.0048	0.0095	0.0095
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0182	0.0182
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0022	0.0002	0.0067
Echinococcus multilocularis	acetylcholinesterase	0.0435	0.1446	0.1446
Mycobacterium tuberculosis	Possible transmembrane cation transporter	0.0126	0.0367	0.1314
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0163	0.0496	0.0496
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Trypanosoma cruzi	hypothetical protein, conserved	0.0126	0.0367	1
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Echinococcus granulosus	neuropeptides capa receptor	0.0022	0.0002	0.0002
Echinococcus granulosus	7TM GPCR rhodopsin	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0022	0.0002	0.0067
Brugia malayi	Carboxylesterase family protein	0.0073	0.0182	0.0976
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	amine GPCR	0.0022	0.0002	0.0002
Echinococcus multilocularis	BC026374 protein (S09 family)	0.0073	0.0182	0.0182
Schistosoma mansoni	calcium-activated potassium channel	0.0126	0.0367	0.0367
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0022	0.0002	0.0002
Echinococcus granulosus	Two pore potassium channel protein sup 9	0.0126	0.0367	0.0367
Mycobacterium tuberculosis	Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO)	0.064	0.2164	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0982	0.336	0.336
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0126	0.0367	1
Loa Loa (eye worm)	TWK-7 protein	0.0126	0.0367	0.0367
Echinococcus granulosus	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 21	0.0126	0.0367	0.1963
Brugia malayi	hypothetical protein	0.0022	0.0002	0.0013
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 12	0.0126	0.0367	0.1963
Plasmodium vivax	hypothetical protein, conserved	0.0048	0.0095	0.2557
Onchocerca volvulus		0.0126	0.0367	1
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Echinococcus granulosus	acetylcholinesterase	0.0435	0.1446	0.1446
Leishmania major	hypothetical protein, conserved	0.0126	0.0367	1
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0095	0.0095
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0048	0.0095	0.0095
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0022	0.0002	0.0002
Mycobacterium ulcerans	ion transport protein	0.0126	0.0367	0.1214
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0126	0.0367	1
Echinococcus granulosus	g protein coupled receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	lipoxygenase	0.006	0.0134	0.0134
Brugia malayi	hypothetical protein	0.0048	0.0095	0.0508
Mycobacterium tuberculosis	POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT)	0.0073	0.0182	0.0422
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	twik family of potassium channels-related	0.0126	0.0367	0.0367
Onchocerca volvulus		0.0126	0.0367	1
Loa Loa (eye worm)	jmjC domain-containing protein	0.0064	0.0148	0.0148
Schistosoma mansoni	hypothetical protein	0.2879	1	1
Schistosoma mansoni	biogenic amine receptor	0.0022	0.0002	0.0002
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0126	0.0367	1
Loa Loa (eye worm)	carboxylesterase	0.0073	0.0182	0.0182
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0182	0.0182
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0022	0.0002	0.0002
Plasmodium falciparum	potassium channel	0.0126	0.0367	0.9881
Onchocerca volvulus		0.0126	0.0367	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0022	0.0002	0.0002
Echinococcus granulosus	potassium channel subfamily K 8	0.0126	0.0367	0.0367
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0022	0.0002	0.0002
Leishmania major	cathepsin L-like protease	0.0069	0.0167	0.2648
Plasmodium vivax	choline kinase, putative	0.0127	0.0371	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0982	0.336	0.336
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0064	0.0148	0.0148
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Schistosoma mansoni	neuropeptide F-like receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0022	0.0002	0.0002
Brugia malayi	hypothetical protein	0.0022	0.0002	0.0013
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0435	0.1446	0.1446
Trypanosoma cruzi	calcium/potassium channel (CAKC), putative	0.0126	0.0367	1
Echinococcus multilocularis	sex peptide receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0022	0.0002	0.0002
Leishmania major	calcium/potassium channel (CAKC), putative	0.0126	0.0367	1
Echinococcus multilocularis	dro:myosuppressin receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	neuropeptide F-like receptor	0.0022	0.0002	0.0002
Trypanosoma cruzi	cysteine peptidase, putative	0.0069	0.0167	0.2648
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Echinococcus multilocularis		0.0048	0.0095	0.0095
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0182	0.0182
Echinococcus multilocularis	g-protein coupled receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	myosin xvIII	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0182	0.0182
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0022	0.0002	0.0013
Trypanosoma cruzi	calcium-activated potassium channel, putative	0.0126	0.0367	1
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0063	0.0146	0.1877
Schistosoma mansoni	neuropeptide receptor	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0022	0.0002	0.0067
Brugia malayi	Melatonin receptor type 1A	0.0022	0.0002	0.0013
Schistosoma mansoni	twik family of potassium channels-related	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0163	0.0496	0.0496
Brugia malayi	AKH receptor	0.0022	0.0002	0.0013
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	G-protein coupled receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	twik family of potassium channels-related	0.0126	0.0367	0.0367
Echinococcus granulosus	neuropeptide receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	allatostatin A receptor	0.0022	0.0002	0.0002
Brugia malayi	hypothetical protein	0.0022	0.0002	0.0013
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0292	0.0947	0.0947
Schistosoma mansoni	gliotactin	0.0073	0.0182	0.0182
Loa Loa (eye worm)	hypothetical protein	0.2879	1	1
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0022	0.0002	0.0002
Echinococcus granulosus	g protein coupled receptor	0.0022	0.0002	0.0002
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0064	0.0148	0.0148
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Brugia malayi	Dopamine receptor	0.0022	0.0002	0.0013
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Echinococcus granulosus	lysine specific demethylase 5A	0.0064	0.0148	0.0148
Mycobacterium tuberculosis	POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT)	0.0073	0.0182	0.0422
Onchocerca volvulus		0.0022	0.0002	0.0067
Brugia malayi	hypothetical protein	0.0073	0.0182	0.0976
Echinococcus granulosus	neuropeptide Y receptor	0.0022	0.0002	0.0002
Giardia lamblia	Hypothetical protein	0.0126	0.0367	0.5
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Echinococcus granulosus	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Echinococcus granulosus	somatostatin receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0022	0.0002	0.0067
Schistosoma mansoni	histamine h1 receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	neuropeptide F receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	neuropeptide f receptor 76f	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0126	0.0367	1
Loa Loa (eye worm)	S-phase kinase-associated protein 1A	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus granulosus	twik family of potassium channels	0.0126	0.0367	0.0367
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 35	0.0126	0.0367	0.1963
Loa Loa (eye worm)	hypothetical protein	0.0322	0.1052	0.1052
Echinococcus multilocularis	conserved hypothetical protein	0.08	0.2723	0.2723
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0022	0.0002	0.0067
Onchocerca volvulus		0.0022	0.0002	0.0067
Echinococcus granulosus	biogenic amine 5HT receptor	0.0022	0.0002	0.0002
Plasmodium falciparum	choline kinase	0.0127	0.0371	1
Brugia malayi	jmjC domain containing protein	0.0064	0.0148	0.0793
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Plasmodium vivax	potassium channel, putative	0.0126	0.0367	0.9881
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Schistosoma mansoni	hypothetical protein	0.0022	0.0002	0.0002
Echinococcus multilocularis	arachidonate 5 lipoxygenase	0.006	0.0134	0.0134
Schistosoma mansoni	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus granulosus	neuropeptide s receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	hypothetical protein	0.1164	0.3998	0.3998
Echinococcus multilocularis	neuropeptide Y receptor	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0022	0.0002	0.0067
Echinococcus granulosus	family S9 non peptidase ue S09 family	0.0073	0.0182	0.0182
Brugia malayi	Dopamine receptor protein 1	0.0022	0.0002	0.0013
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0022	0.0002	0.0013
Echinococcus granulosus	neuroligin	0.0073	0.0182	0.0182
Brugia malayi	jmjC domain containing protein	0.0064	0.0148	0.0793
Echinococcus granulosus	microtubule associated protein 2	0.0747	0.2538	0.2538
Echinococcus granulosus	arachidonate 5 lipoxygenase	0.006	0.0134	0.0134
Echinococcus granulosus	sex peptide receptor	0.0022	0.0002	0.0002
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Brugia malayi	RE15519p	0.0022	0.0002	0.0013
Schistosoma mansoni	amine oxidase	0.0048	0.0095	0.0095
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Loa Loa (eye worm)	neuropeptide F receptor	0.0022	0.0002	0.0002
Schistosoma mansoni	twik family of potassium channels-related	0.0126	0.0367	0.0367
Echinococcus multilocularis	G protein coupled receptor 139	0.0022	0.0002	0.0002
Schistosoma mansoni	calcium-activated potassium channel	0.2879	1	1
Schistosoma mansoni	twik family of potassium channels-related	0.0126	0.0367	0.0367
Echinococcus granulosus	fmrfamide receptor	0.0022	0.0002	0.0002
Brugia malayi	Carboxylesterase family protein	0.0073	0.0182	0.0976
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0022	0.0002	0.0002
Loa Loa (eye worm)	carboxylesterase	0.0073	0.0182	0.0182
Schistosoma mansoni	adenoreceptor	0.0022	0.0002	0.0002
Onchocerca volvulus		0.0126	0.0367	1
Leishmania major	potassium channel subunit-like protein	0.0126	0.0367	1
Trypanosoma cruzi	calcium-activated potassium channel, putative	0.0126	0.0367	1
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0022	0.0002	0.0002
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0022	0.0002	0.0002
Brugia malayi	ORL1-like opioid receptor	0.0022	0.0002	0.0013
Onchocerca volvulus		0.0022	0.0002	0.0067
Echinococcus multilocularis	twik family of potassium channels	0.0126	0.0367	0.0367
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0022	0.0002	0.0002
Toxoplasma gondii	ion channel protein	0.0126	0.0367	0.984
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0022	0.0002	0.0002
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0022	0.0002	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0182	0.0182
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Echinococcus granulosus	potassium channel subfamily K	0.0126	0.0367	0.0367
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0002	0.0002
Brugia malayi	hypothetical protein	0.0126	0.0367	0.1963
Echinococcus multilocularis	calcium activated potassium channel variant	0.0126	0.0367	0.0367
Brugia malayi	Serotonin receptor	0.0555	0.1868	1
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0367	0.0367
Toxoplasma gondii	phosphotransferase enzyme family protein	0.0127	0.0371	1
Brugia malayi	amine oxidase, flavin-containing family protein	0.0048	0.0095	0.0508
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0022	0.0002	0.0002
Mycobacterium ulcerans	flavin-containing monoamine oxidase AofH	0.0688	0.2333	1
Loa Loa (eye worm)	G-protein coupled receptor	0.0022	0.0002	0.0002
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0022	0.0002	0.0002
Trypanosoma cruzi	calcium/potassium channel (CAKC), putative	0.0126	0.0367	1

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 24 uM	Inhibitory concentration against Streptococcus pneumoniae chorismate synthase	ChEMBL.	12565943
IC50 (binding)	= 24 uM	Inhibitory concentration against Streptococcus pneumoniae chorismate synthase	ChEMBL.	12565943

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 233762