TDR Targets

Basic information

Technical information

TDR Targets ID: 261374
Name: (4-phenylphenyl)methyl 2-(4-bromophenyl)-6-ch loro-8-methylquinoline-4-carboxylate
MW: 542.85 | Formula: C30H21BrClNO2
H donors: 0 H acceptors: 2 LogP: 8.51 Rotable bonds: 6
Rule of 5 violations (Lipinski): 2
SMILES: Clc1cc(C)c2c(c1)c(cc(n2)c1ccc(cc1)Br)C(=O)OCc1ccc(cc1)c1ccccc1
InChi: 1S/C30H21BrClNO2/c1-19-15-25(32)16-26-27(17-28(33-29(19)26)23-11-13-24(31)14-12-23)30(34)35-18-20-7-9-22(10-8-20)21-5-3-2-4-6-21/h2-17H,18H2,1H3
InChiKey: NJLFIHLPSYNLGF-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

(4-phenylphenyl)methyl 2-(4-bromophenyl)-6-chloro-8-methyl-quinoline-4-carboxylate
2-(4-bromophenyl)-6-chloro-8-methyl-4-quinolinecarboxylic acid (4-phenylphenyl)methyl ester
2-(4-bromophenyl)-6-chloro-8-methyl-cinchonin (4-phenylbenzyl) ester
2-(4-bromophenyl)-6-chloro-8-methyl-cinchoninic acid (4-phenylbenzyl) ester
AIDS228078
4-Quinolinecarboxylic acid, 2-(4-bromophenyl)-6-chloro-8-methyl-, [1,1'-biphenyl]-4-ylmethyl ester
AIDS-228078

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Candida albicans	Prolyl-tRNA synthetase	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Mycobacterium tuberculosis	Probable prolyl-tRNA synthetase ProS (proline--tRNA ligase) (PRORS) (global RNA synthesis factor) (proline translase)	Get druggable targets OG5_128299	All targets in OG5_128299
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128299	All targets in OG5_128299
Wolbachia endosymbiont of Brugia malayi	prolyl-tRNA synthetase	Get druggable targets OG5_128299	All targets in OG5_128299
Plasmodium vivax	proline--tRNA ligase, putative	Get druggable targets OG5_128299	All targets in OG5_128299
Plasmodium yoelii	prolyl-tRNA synthetase-related	Get druggable targets OG5_128299	All targets in OG5_128299
Brugia malayi	probable proline-trna synthetase - fission yeast, putative	Get druggable targets OG5_128299	All targets in OG5_128299
Babesia bovis	tRNA synthetase class II core domain containing protein	Get druggable targets OG5_128299	All targets in OG5_128299
Treponema pallidum	prolyl-tRNA synthetase	Get druggable targets OG5_128299	All targets in OG5_128299
Theileria parva	prolyl-tRNA synthetase, putative	Get druggable targets OG5_128299	All targets in OG5_128299
Schistosoma mansoni	prolyl-tRNA synthetase	Get druggable targets OG5_128299	All targets in OG5_128299
Mycobacterium ulcerans	prolyl-tRNA synthetase	Get druggable targets OG5_128299	All targets in OG5_128299
Plasmodium knowlesi	proline--tRNA ligase, putative	Get druggable targets OG5_128299	All targets in OG5_128299
Plasmodium berghei	proline--tRNA ligase, putative	Get druggable targets OG5_128299	All targets in OG5_128299
Plasmodium falciparum	proline--tRNA ligase, putative	Get druggable targets OG5_128299	All targets in OG5_128299
Echinococcus multilocularis	prolyl tRNA synthetase, mitochondrial	Get druggable targets OG5_128299	All targets in OG5_128299
Brugia malayi	Met-10+ like-protein	Get druggable targets OG5_128299	All targets in OG5_128299
Schistosoma japonicum	ko:K01881 prolyl-tRNA synthetase [EC6.1.1.15], putative	Get druggable targets OG5_128299	All targets in OG5_128299
Echinococcus granulosus	prolyl tRNA synthetase mitochondrial	Get druggable targets OG5_128299	All targets in OG5_128299
Chlamydia trachomatis	proline--tRNA ligase	Get druggable targets OG5_128299	All targets in OG5_128299
Schistosoma japonicum	Probable prolyl-tRNA synthetase, mitochondrial precursor, putative	Get druggable targets OG5_128299	All targets in OG5_128299

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Leishmania braziliensis	threonyl-tRNA synthetase, putative	Prolyl-tRNA synthetase	575 aa	501 aa	18.4 %
Leishmania donovani	threonyl-tRNA synthetase, putative	Prolyl-tRNA synthetase	575 aa	498 aa	18.3 %
Leishmania mexicana	threonyl-tRNA synthetase, putative	Prolyl-tRNA synthetase	575 aa	482 aa	18.3 %
Leishmania major	threonyl-tRNA synthetase, putative	Prolyl-tRNA synthetase	575 aa	477 aa	18.2 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Leishmania major	diacylglycerol acyltransferase, putative	0.0199	0.0267	0.1996
Entamoeba histolytica	membrane-bound O-acyltransferase (MBOAT ) family protein	0.0053	0.0043	1
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0222	0.0303	0.0303
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0039	0.0022	0.0022
Mycobacterium ulcerans	hypothetical protein	0.0199	0.0267	1
Loa Loa (eye worm)	diacylglycerol acyltransferase	0.0897	0.1338	0.1338
Loa Loa (eye worm)	hhat protein	0.0053	0.0043	0.0043
Schistosoma mansoni	tar DNA-binding protein	0.0057	0.005	0.005
Leishmania major	glycerol uptake protein, putative	0.0053	0.0043	0.0324
Echinococcus granulosus	diacylglycerol O acyltransferase 1	0.0315	0.0445	0.0445
Trypanosoma cruzi	glycerol uptake protein, putative	0.0053	0.0043	0.0324
Echinococcus multilocularis	o acyltransferase (membrane bound) domain	0.0053	0.0043	0.0043
Schistosoma mansoni	diacylglycerol O-acyltransferase 1	0.0315	0.0445	0.0445
Schistosoma mansoni	sterol O-acyltransferase 1	0.0053	0.0043	0.0043
Echinococcus granulosus	lysophospholipid acyltransferase 7	0.0053	0.0043	0.0043
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0089	0.0099	0.4101
Trypanosoma brucei	glycerol uptake protein, putative	0.0053	0.0043	0.0324
Brugia malayi	diacylglycerol acyltransferase	0.0315	0.0445	0.0445
Mycobacterium tuberculosis	Probable reductase	0.0089	0.0099	0.4101
Wolbachia endosymbiont of Brugia malayi	prolyl-tRNA synthetase	0.0045	0.0032	0.5
Leishmania major	glycerol uptake protein, putative	0.0053	0.0043	0.0324
Echinococcus granulosus	membrane bound acyltransferase:hhat	0.0053	0.0043	0.0043
Trypanosoma brucei	trypanothione reductase	0.0039	0.0022	0.0167
Toxoplasma gondii	mono- or diacylglycerol acyltransferase	0.0199	0.0267	0.1996
Leishmania major	glycerol uptake protein, putative	0.0053	0.0043	0.0324
Loa Loa (eye worm)	hhat protein	0.0053	0.0043	0.0043
Plasmodium falciparum	diacylglycerol O-acyltransferase	0.0315	0.0445	1
Echinococcus granulosus	sterol O acyltransferase 1	0.0053	0.0043	0.0043
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0099	0.0115	0.4834
Trypanosoma brucei	diacylglycerol acyltransferase, putative	0.0897	0.1338	1
Echinococcus granulosus	alpha 16 mannosyl glycoprotein	0.6543	1	1
Mycobacterium tuberculosis	Probable oxidoreductase	0.0099	0.0115	0.4834
Loa Loa (eye worm)	hypothetical protein	0.6543	1	1
Toxoplasma gondii	thioredoxin reductase	0.0039	0.0022	0.0167
Echinococcus granulosus	protein cysteine N palmitoyltransferase	0.0053	0.0043	0.0043
Echinococcus multilocularis	tar DNA binding protein	0.0057	0.005	0.005
Echinococcus granulosus	o acyltransferase membrane bound domain	0.0053	0.0043	0.0043
Echinococcus granulosus	o acyltransferase membrane bound domain	0.0053	0.0043	0.0043
Brugia malayi	diacylglycerol acyltransferase family protein	0.0897	0.1338	0.1338
Brugia malayi	MBOAT family protein	0.0053	0.0043	0.0043
Trypanosoma cruzi	diacylglycerol acyltransferase, putative	0.0199	0.0267	0.1996
Echinococcus multilocularis	protein cysteine N palmitoyltransferase	0.0053	0.0043	0.0043
Plasmodium vivax	diacylglycerol O-acyltransferase, putative	0.0315	0.0445	1
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0032	0.0032
Loa Loa (eye worm)	MBOAT family protein	0.0053	0.0043	0.0043
Treponema pallidum	alginate O-acetylation protein (algI)	0.0053	0.0043	1
Loa Loa (eye worm)	thioredoxin reductase	0.0039	0.0022	0.0022
Trypanosoma cruzi	GUP1, putative	0.0053	0.0043	0.0324
Loa Loa (eye worm)	TAR-binding protein	0.0057	0.005	0.005
Mycobacterium ulcerans	prolyl-tRNA synthetase	0.0045	0.0032	0.1197
Leishmania major	diacylglycerol acyltransferase, putative	0.0199	0.0267	0.1996
Entamoeba histolytica	membrane-bound O-acyltransferase (MBOAT ) family protein	0.0053	0.0043	1
Echinococcus multilocularis	prolyl tRNA synthetase, mitochondrial	0.0038	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0043	0.0043
Mycobacterium tuberculosis	Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase)	0.017	0.0223	1
Schistosoma mansoni	leukocyte receptor cluster (lrc) member 4 protein	0.0053	0.0043	0.0043
Schistosoma mansoni	hypothetical protein	0.0199	0.0267	0.0267
Trichomonas vaginalis	conserved hypothetical protein	0.0092	0.0104	1
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0039	0.0022	0.041
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0043	0.0043
Trichomonas vaginalis	porcupine, putative	0.0053	0.0043	0.4184
Trichomonas vaginalis	conserved hypothetical protein	0.0092	0.0104	1
Echinococcus granulosus	leukotriene A 4 hydrolase	0.0464	0.0673	0.0673
Schistosoma mansoni	diacylglycerol O-acyltransferase 1	0.0897	0.1338	0.1338
Schistosoma mansoni	tar DNA-binding protein	0.0057	0.005	0.005
Leishmania major	trypanothione reductase	0.0039	0.0022	0.0167
Brugia malayi	MBOAT family protein	0.0053	0.0043	0.0043
Trypanosoma brucei	glycerol uptake protein, putative	0.0053	0.0043	0.0324
Echinococcus multilocularis	diacylglycerol O acyltransferase 1	0.0315	0.0445	0.0445
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0089	0.0099	0.4101
Trypanosoma cruzi	trypanothione reductase, putative	0.0039	0.0022	0.0167
Brugia malayi	Met-10+ like-protein	0.0034	0.0014	0.0014
Loa Loa (eye worm)	RNA binding protein	0.0057	0.005	0.005
Loa Loa (eye worm)	hypothetical protein	0.0262	0.0364	0.0364
Brugia malayi	RNA binding protein	0.0057	0.005	0.005
Trypanosoma cruzi	diacylglycerol acyltransferase, putative	0.0199	0.0267	0.1996
Schistosoma mansoni	hypothetical protein	0.0053	0.0043	0.0043
Toxoplasma gondii	acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha	0.0315	0.0445	0.3326
Echinococcus granulosus	tar DNA binding protein	0.0057	0.005	0.005
Entamoeba histolytica	vacuolar protein sorting 26	0.0053	0.0043	1
Echinococcus multilocularis	leukotriene A 4 hydrolase	0.0464	0.0673	0.0673
Plasmodium vivax	thioredoxin reductase, putative	0.0039	0.0022	0.0503
Echinococcus granulosus	prolyl tRNA synthetase mitochondrial	0.0038	0.0021	0.0021
Entamoeba histolytica	hypothetical protein, conserved	0.0053	0.0043	1
Brugia malayi	Thioredoxin reductase	0.0039	0.0022	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0043	0.0043
Entamoeba histolytica	membrane-bound O-acyltransferase (MBOAT ) family protein	0.0053	0.0043	1
Toxoplasma gondii	hypothetical protein	0.0036	0.0017	0.013
Plasmodium vivax	glutathione reductase, putative	0.0039	0.0022	0.0503
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0089	0.0099	0.4101
Brugia malayi	MBOAT family protein	0.0053	0.0043	0.0043
Loa Loa (eye worm)	MBOAT family protein	0.0053	0.0043	0.0043
Schistosoma mansoni	membrane-bound acyltransferase/hhat	0.0053	0.0043	0.0043
Echinococcus granulosus	Membrane bound O acyl transferase MBOAT	0.0053	0.0043	0.0043
Trypanosoma cruzi	GUP1, putative	0.0053	0.0043	0.0324
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0099	0.0115	0.4834
Echinococcus multilocularis	o acyltransferase (membrane bound) domain	0.0053	0.0043	0.0043
Schistosoma mansoni	leukotriene A4 hydrolase (M01 family)	0.0464	0.0673	0.0673
Echinococcus granulosus	o acyltransferase membrane bound domain	0.0053	0.0043	0.0043
Trichomonas vaginalis	conserved hypothetical protein	0.0092	0.0104	1
Trichomonas vaginalis	conserved hypothetical protein	0.0092	0.0104	1
Schistosoma mansoni	o-acyltransferase (membrane bound) domain containing protein	0.0053	0.0043	0.0043
Loa Loa (eye worm)	glutathione reductase	0.0039	0.0022	0.0022
Loa Loa (eye worm)	diacylglycerol acyltransferase	0.0315	0.0445	0.0445
Leishmania major	glycerol uptake protein, putative	0.0053	0.0043	0.0324
Brugia malayi	probable proline-trna synthetase - fission yeast, putative	0.0045	0.0032	0.0032
Onchocerca volvulus		0.0053	0.0043	0.0324
Loa Loa (eye worm)	leukotriene A4 hydrolase	0.0464	0.0673	0.0673
Trypanosoma cruzi	glycerol uptake protein, putative	0.0053	0.0043	0.0324
Trichomonas vaginalis	conserved hypothetical protein	0.0092	0.0104	1
Echinococcus multilocularis	Membrane bound O acyl transferase, MBOAT	0.0053	0.0043	0.0043
Trypanosoma cruzi	glycerol uptake protein, putative	0.0053	0.0043	0.0324
Trichomonas vaginalis	conserved hypothetical protein	0.0053	0.0043	0.4184
Leishmania major	hypothetical protein, unknown function,protein, unknown function	0.0199	0.0267	0.1996
Toxoplasma gondii	dgat2l1-prov protein	0.0897	0.1338	1
Trichomonas vaginalis	transmembrane protein nessy, putative	0.0053	0.0043	0.4184
Trichomonas vaginalis	conserved hypothetical protein	0.0092	0.0104	1
Toxoplasma gondii	acyl-CoA:diacylglycerol acyltransferase 1-related enzyme	0.0315	0.0445	0.3326
Schistosoma mansoni	o-acyltransferase (membrane bound) domain containing protein	0.0053	0.0043	0.0043
Trichomonas vaginalis	conserved hypothetical protein	0.0053	0.0043	0.4184
Echinococcus multilocularis	alpha 1,6 mannosyl glycoprotein	0.6543	1	1
Brugia malayi	TAR-binding protein	0.0057	0.005	0.005
Loa Loa (eye worm)	membrane bound O-acyltransferase domain containing 1	0.0053	0.0043	0.0043
Schistosoma mansoni	tar DNA-binding protein	0.0057	0.005	0.005
Trypanosoma cruzi	diacylglycerol acyltransferase, putative	0.0199	0.0267	0.1996
Brugia malayi	MBOAT family protein	0.0053	0.0043	0.0043
Trichomonas vaginalis	conserved hypothetical protein	0.0056	0.0048	0.4676
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0057	0.005	0.005
Brugia malayi	RNA recognition motif domain containing protein	0.0057	0.005	0.005
Leishmania major	glycerol uptake protein, putative	0.0053	0.0043	0.0324
Trichomonas vaginalis	conserved hypothetical protein	0.0092	0.0104	1
Trypanosoma cruzi	diacylglycerol acyltransferase, putative	0.0897	0.1338	1
Trypanosoma cruzi	diacylglycerol acyltransferase, putative	0.0199	0.0267	0.1996
Schistosoma mansoni	tar DNA-binding protein	0.0057	0.005	0.005
Plasmodium vivax	proline--tRNA ligase, putative	0.0038	0.0021	0.0473
Schistosoma mansoni	prolyl-tRNA synthetase	0.0038	0.0021	0.0021
Plasmodium falciparum	thioredoxin reductase	0.0039	0.0022	0.0503
Brugia malayi	hypothetical protein	0.0213	0.0289	0.0289
Echinococcus multilocularis	sterol O acyltransferase 1	0.0053	0.0043	0.0043
Loa Loa (eye worm)	MBOAT family protein	0.0053	0.0043	0.0043
Brugia malayi	Hhat protein	0.0053	0.0043	0.0043
Echinococcus granulosus	thioredoxin glutathione reductase	0.0039	0.0022	0.0022
Leishmania major	diacylglycerol acyltransferase, putative	0.0897	0.1338	1
Schistosoma mansoni	diacylglycerol O-acyltransferase	0.0199	0.0267	0.0267
Mycobacterium ulcerans	epoxide hydrolase EphA	0.017	0.0223	0.834
Schistosoma mansoni	zinc finger protein	0.0053	0.0043	0.0043
Trichomonas vaginalis	conserved hypothetical protein	0.0092	0.0104	1
Schistosoma mansoni	tar DNA-binding protein	0.0057	0.005	0.005
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0089	0.0099	0.4101
Trichomonas vaginalis	conserved hypothetical protein	0.0053	0.0043	0.4184
Plasmodium falciparum	proline--tRNA ligase, putative	0.0038	0.0021	0.0473
Brugia malayi	MBOAT family protein	0.0053	0.0043	0.0043
Chlamydia trachomatis	proline--tRNA ligase	0.0045	0.0032	0.5
Echinococcus multilocularis	lysophospholipid acyltransferase 7	0.0053	0.0043	0.0043
Toxoplasma gondii	hypothetical protein	0.0053	0.0043	0.0324
Echinococcus multilocularis	membrane bound acyltransferase:hhat	0.0053	0.0043	0.0043
Mycobacterium tuberculosis	Probable dehydrogenase	0.0089	0.0099	0.4101
Schistosoma mansoni	o-acyltransferase (membrane bound) domain containing protein	0.0053	0.0043	0.0043
Trypanosoma cruzi	diacylglycerol acyltransferase, putative	0.0897	0.1338	1
Schistosoma mansoni	beta-12-n-acetylglucosaminyltransferase II	0.6543	1	1
Toxoplasma gondii	diacylglycerol acyltransferase	0.0199	0.0267	0.1996
Trypanosoma brucei	diacylglycerol acyltransferase, putative	0.0199	0.0267	0.1996
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0099	0.0115	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0043	0.0043
Onchocerca volvulus		0.0897	0.1338	1
Entamoeba histolytica	hypothetical protein	0.0053	0.0043	1
Leishmania major	hypothetical protein, conserved	0.0053	0.0043	0.0324
Schistosoma mansoni	diacylglycerol O-acyltransferase	0.0199	0.0267	0.0267
Echinococcus multilocularis	o acyltransferase (membrane bound) domain	0.0053	0.0043	0.0043
Brugia malayi	glutathione reductase	0.0039	0.0022	0.0022
Plasmodium falciparum	glutathione reductase	0.0039	0.0022	0.0503

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 8.8 uM	Aminoacylation activity against Candida albicans prolyl-tRNA synthetase	ChEMBL.	11229766
IC50 (binding)	= 8.8 uM	Aminoacylation activity against Candida albicans prolyl-tRNA synthetase	ChEMBL.	11229766
IC50 (binding)	> 100 uM	Aminoacylation activity against human prolyl-tRNA synthetase	ChEMBL.	11229766
IC50 (binding)	> 100 uM	Aminoacylation activity against human prolyl-tRNA synthetase	ChEMBL.	11229766

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL153564
PubChem: 5275536

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 261374