Detailed information for compound 274191

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 363.15 | Formula: C15H10INO2
  • H donors: 0 H acceptors: 1 LogP: 3.94 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc2c(c1)c(=O)oc(n2)c1ccccc1I
  • InChi: 1S/C15H10INO2/c1-9-6-7-13-11(8-9)15(18)19-14(17-13)10-4-2-3-5-12(10)16/h2-8H,1H3
  • InChiKey: XQOKPVZGYQLUQC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens complement component 1, r subcomponent Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0132 0.0437
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0089 0.0903
Plasmodium vivax telomerase reverse transcriptase, putative 0.0612 0.2681 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0015 0.0058
Echinococcus granulosus expressed conserved protein 0.0091 0.0339 0.113
Loa Loa (eye worm) hypothetical protein 0.0042 0.0117 0.0619
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0015 0.0058
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0015 0.0044
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0089 0.0903
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1221 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0035 0.0479
Leishmania major DNA polymerase eta, putative 0.0019 0.0015 0.0058
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0365 0.1219
Loa Loa (eye worm) hypothetical protein 0.0113 0.0438 0.2323
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0046 0.0139 0.1026
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0132 0.0701
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0014
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0021 0.0024 0.0127
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0457 0.2425
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0089 0.0291
Brugia malayi Protein kinase domain containing protein 0.0406 0.1757 0.2423
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0015 0.012
Echinococcus multilocularis Protein lozenge 0.0055 0.0176 0.0582
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0089 0.0731
Brugia malayi beta-lactamase family protein 0.0035 0.0089 0.0123
Mycobacterium ulcerans beta-lactamase 0.0035 0.0089 0.1462
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0016 0.0003 0.0014
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.015 0.0207
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0015 0.0126
Schistosoma mansoni hypothetical protein 0.004 0.011 0.0361
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0035 0.0479
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0015 0.0126
Toxoplasma gondii RNA-directed DNA polymerase 0.0612 0.2681 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0185
Echinococcus multilocularis fibrillin 1 0.0016 0.0003 0.0001
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0068 0.0237 0.1258
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0035 0.0479
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0185
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0089 0.0903
Trypanosoma brucei telomerase reverse transcriptase 0.0612 0.2681 1
Schistosoma mansoni hypothetical protein 0.004 0.011 0.0361
Echinococcus multilocularis microtubule associated protein 2 0.0678 0.2977 1
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0612 0.2681 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0014
Mycobacterium ulcerans hypothetical protein 0.0023 0.0035 0.0479
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0089 0.0903
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0068 0.0237 0.079
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0089 0.0292
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0561 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1221 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0089 0.0123
Schistosoma mansoni tsg101-related 0.0057 0.0186 0.0616
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0089 0.1462
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0002 0.0008
Onchocerca volvulus 0.0035 0.0089 0.0086
Loa Loa (eye worm) runx1 0.0055 0.0176 0.0931
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0015 0.0043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0117 0.0957
Schistosoma mansoni single-minded 0.006 0.0199 0.0659
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0035 0.013
Echinococcus granulosus laminin 0.0016 0.0003 0.0001
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0372 0.124
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0132 0.0182
Brugia malayi bHLH-PAS transcription factor 0.0044 0.0129 0.0178
Loa Loa (eye worm) hypothetical protein 0.0033 0.0081 0.0428
Onchocerca volvulus 0.0035 0.0089 0.0086
Leishmania major telomerase reverse transcriptase, putative 0.0612 0.2681 1
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0551 0.1846
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0561 0.5909
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0008 0.0045
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0015 0.0082
Schistosoma mansoni hypothetical protein 0.0033 0.0081 0.0262
Schistosoma mansoni tsg101-related 0.0057 0.0186 0.0616
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0089 0.1591
Loa Loa (eye worm) hypothetical protein 0.0435 0.1886 1
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.1221 0.5
Trichomonas vaginalis hypothetical protein 0.0033 0.008 0.0654
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0365 0.1219
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0473
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0185
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0457 0.2425
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.1221 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0089 0.0473
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0473
Giardia lamblia Telomerase catalytic subunit 0.0612 0.2681 1
Echinococcus multilocularis transfer RNA-Lys 0.0044 0.0129 0.0426
Schistosoma mansoni tsg101-related 0.0046 0.0139 0.0458
Mycobacterium leprae Probable lipase LipE 0.0035 0.0089 0.1591
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0002 0.0008
Echinococcus granulosus dna polymerase eta 0.0019 0.0015 0.0044
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0132 0.0437
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0473
Mycobacterium tuberculosis Conserved protein 0.0035 0.0089 0.0903
Loa Loa (eye worm) hypothetical protein 0.0435 0.1886 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0089 0.0731
Toxoplasma gondii ABC1 family protein 0.0035 0.0089 0.0323
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0002 0.0008
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0035 0.0162
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0035 0.0048
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0089 0.0731
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.015 0.0797
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0014
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0015 0.0021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0127
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1221 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0015 0.0058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0132 0.0435
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0117 0.0385
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0612 0.2681 1
Leishmania major hypothetical protein, conserved 0.0022 0.0028 0.0106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0035 0.0326
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0035 0.0479
Loa Loa (eye worm) beta-lactamase 0.0035 0.0089 0.0473
Loa Loa (eye worm) hypothetical protein 0.0097 0.0365 0.1935
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0035 0.0162
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0081 0.0111
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0035 0.0623
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0035 0.0162
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0015 0.012
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0551 0.1846
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0035 0.0479
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.1221 0.4522
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0035 0.013
Echinococcus granulosus single minded 2 0.0044 0.0129 0.0426
Echinococcus multilocularis laminin 0.0016 0.0003 0.0001
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0068 0.0237 0.079
Mycobacterium ulcerans hypothetical protein 0.0035 0.0089 0.1462
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0132 0.0435
Mycobacterium ulcerans lipase LipD 0.0035 0.0089 0.1462
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1221 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0075 0.0398
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0015 0.0044
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0089 0.0903
Mycobacterium ulcerans putative regulatory protein 0.0044 0.0129 0.2182
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0089 0.0277
Brugia malayi beta-lactamase family protein 0.0035 0.0089 0.0123
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0021 0.0024 0.0071
Echinococcus multilocularis Tolloid protein 1 0.0021 0.0024 0.0073
Brugia malayi PAS domain containing protein 0.006 0.0199 0.0274
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0113 0.0438 0.0604
Brugia malayi CHE-14 protein 0.0042 0.0117 0.0161
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0035 0.0479
Mycobacterium tuberculosis Conserved protein 0.0035 0.0089 0.0903
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0089 0.0731
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1221 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0473
Echinococcus granulosus Tolloid protein 1 0.0021 0.0024 0.0073
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0089 0.0903
Echinococcus multilocularis aryl hydrocarbon receptor 0.0129 0.051 0.1707
Mycobacterium tuberculosis Conserved protein 0.0035 0.0089 0.0903
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1221 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0117 0.0385
Loa Loa (eye worm) hypothetical protein 0.0114 0.044 0.2335
Plasmodium falciparum telomerase reverse transcriptase 0.0612 0.2681 1
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0089 0.0302
Schistosoma mansoni microtubule-associated protein tau 0.0678 0.2977 1
Onchocerca volvulus 0.0035 0.0089 0.0086
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0015 0.0058
Echinococcus granulosus microtubule associated protein 2 0.0678 0.2977 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.1221 1
Brugia malayi Telomerase reverse transcriptase 0.1629 0.725 1
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0015 0.0127
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0089 0.0291
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0132 0.0435
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0132 0.0437
Leishmania major protein kinase, putative 0.0016 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0035 0.0048
Echinococcus multilocularis dna polymerase eta 0.0019 0.0015 0.0044
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0035 0.0623
Leishmania major hypothetical protein, conserved 0.0035 0.0089 0.0333
Brugia malayi hypothetical protein 0.0435 0.1886 0.2601
Brugia malayi Fibulin-1 precursor 0.0016 0.0003 0.0004
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0089 0.1462
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0089 0.0903
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0045
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.0028 0.0106
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0473
Echinococcus granulosus aryl hydrocarbon receptor 0.0129 0.051 0.1707
Brugia malayi hypothetical protein 0.0068 0.0237 0.0327
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0035 0.0048
Schistosoma mansoni DNA polymerase eta 0.0019 0.0015 0.0043
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0016 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0049 0.015 0.0797
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0089 0.0731
Loa Loa (eye worm) hypothetical protein 0.0051 0.0159 0.0842
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.0946 1
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0117 0.0385
Onchocerca volvulus 0.0435 0.1886 0.1884
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0561 1
Echinococcus multilocularis expressed conserved protein 0.0091 0.0339 0.113
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0015 0.0127
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0035 0.0479
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0035 0.0326
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0015 0.0058
Schistosoma mansoni patched 1 0.0042 0.0117 0.0383
Onchocerca volvulus 0.0023 0.0035 0.0032
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0406 0.1757 0.9317
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0015 0.0021
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0365 0.29
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0089 0.0333
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0045
Leishmania major protein kinase, putative 0.0016 0.0002 0.0008
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0008 1
Leishmania major DNA polymerase kappa, putative 0.0019 0.0015 0.0058
Echinococcus multilocularis protein patched 0.0042 0.0117 0.0385
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0015 0.0058
Loa Loa (eye worm) hypothetical protein 0.0129 0.0508 0.2693
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0365 0.0503
Onchocerca volvulus 0.0129 0.0508 0.0505
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0117 0.0619
Schistosoma mansoni hypothetical protein 0.004 0.011 0.0361
Brugia malayi MH2 domain containing protein 0.0117 0.0457 0.0631
Echinococcus multilocularis protein dispatched 1 0.0047 0.0143 0.0473
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0035 0.013
Onchocerca volvulus 0.0045 0.0131 0.0129
Brugia malayi beta-lactamase 0.0035 0.0089 0.0123
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0089 0.0292
Echinococcus granulosus dna polymerase kappa 0.0019 0.0015 0.0044
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0015 0.0043
Schistosoma mansoni lozenge 0.0055 0.0176 0.0581
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0016 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0089 0.0333
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0473
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0016 0.0003 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0132 0.0437
Schistosoma mansoni hypothetical protein 0.004 0.011 0.0361
Schistosoma mansoni aryl hydrocarbon receptor 0.0173 0.0709 0.2374
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1221 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.015 0.0207
Trichomonas vaginalis esterase, putative 0.0035 0.0089 0.0731
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1221 1
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.0028 0.0049
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0015 0.0044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0045

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 10 uM Inhibition of C1r serine protease ChEMBL. No reference
IC50 (binding) = 10 uM Inhibition of C1r serine protease ChEMBL. No reference
IC50 (binding) = 51 uM Inhibitory activity against C1r serine protease ChEMBL. No reference
IC50 (binding) = 51 uM Inhibitory activity against C1r serine protease ChEMBL. No reference
IC50 (binding) > 62.5 uM Inhibitory activity against C1r serine protease ChEMBL. No reference
IC50 (binding) > 62.5 uM Inhibitory activity against C1r serine protease ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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