Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine proteinase, putative | 0.0078 | 0.0455 | 1 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0268 | 0.0155 |
Brugia malayi | G-protein coupled receptor | 0.009 | 0.056 | 0.056 |
Schistosoma mansoni | adenoreceptor | 0.009 | 0.056 | 0.1193 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | amine GPCR | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | g-protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.009 | 0.056 | 0.056 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.056 | 0.1193 |
Onchocerca volvulus | Cathepsin F homolog | 0.0078 | 0.0455 | 0.6383 |
Echinococcus granulosus | cathepsin l1 | 0.0056 | 0.0268 | 0.0533 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Echinococcus granulosus | fmrfamide receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | neuropeptide s receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0053 | 0.0238 | 0.044 |
Echinococcus granulosus | insulin receptor | 0.0053 | 0.0238 | 0.044 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.009 | 0.056 | 0.1427 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0455 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0455 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0056 | 0.0268 | 0.3182 |
Echinococcus granulosus | cysteine protease | 0.0046 | 0.0181 | 0.0266 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0078 | 0.0455 | 0.9964 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.5 |
Echinococcus multilocularis | insulin receptor | 0.0053 | 0.0238 | 0.044 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.1108 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0416 | 0.3359 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0078 | 0.0455 | 0.0343 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0056 | 0.0268 | 0.0274 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0053 | 0.0238 | 0.0124 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | Cathepsin L homolog | 0.0078 | 0.0455 | 0.6383 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0078 | 0.0455 | 0.1104 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Loa Loa (eye worm) | neuropeptide F receptor | 0.009 | 0.056 | 0.045 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.0456 | 0.4311 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0078 | 0.0455 | 0.0343 |
Schistosoma mansoni | opsin-like receptor | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0135 | 0.0021 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0145 | 0.1035 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Loa Loa (eye worm) | fibroinase | 0.0078 | 0.0455 | 0.0343 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0056 | 0.0268 | 0.0274 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.009 | 0.056 | 0.1427 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.0416 | 0.3359 | 0.3281 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | cathepsin L-like precursor | 0.0056 | 0.0268 | 0.0268 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.009 | 0.056 | 0.1427 |
Brugia malayi | larval opioid receptor | 0.009 | 0.056 | 0.056 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0145 | 0.1035 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Brugia malayi | G protein-coupled receptor | 0.009 | 0.056 | 0.056 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0416 | 0.3359 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Plasmodium vivax | unspecified product | 0.0046 | 0.0181 | 0.3734 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0051 | 0.0226 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0078 | 0.0455 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0046 | 0.0181 | 0.3734 |
Schistosoma mansoni | amine GPCR | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | myosin xvIII | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0056 | 0.0268 | 0.1018 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0078 | 0.0455 | 0.086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | serotonin receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | sex peptide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.009 | 0.056 | 0.1427 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0078 | 0.0455 | 0.9964 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0046 | 0.0181 | 0.0181 |
Loa Loa (eye worm) | TYRA-2 protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | cathepsin L | 0.0046 | 0.0181 | 0.0266 |
Echinococcus multilocularis | cysteine protease | 0.0078 | 0.0455 | 0.1104 |
Brugia malayi | Melatonin receptor type 1A | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.009 | 0.056 | 0.1427 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0078 | 0.0455 | 0.1104 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | neuropeptide receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | biogenic amine receptor | 0.009 | 0.056 | 0.1193 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | orexin receptor type 2 | 0.009 | 0.056 | 0.1427 |
Giardia lamblia | Cathepsin B precursor | 0.0145 | 0.1035 | 0.5 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 1 |
Echinococcus multilocularis | sex peptide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | cysteine protease | 0.0078 | 0.0455 | 0.1104 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0145 | 0.1035 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | ORL1-like opioid receptor | 0.009 | 0.056 | 0.056 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0455 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.0226 | 0.4744 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0416 | 0.3359 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0152 | 0.0037 |
Echinococcus granulosus | cathepsin b | 0.0416 | 0.3359 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.009 | 0.056 | 0.1193 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Brugia malayi | Protein kinase domain containing protein | 0.0053 | 0.0238 | 0.0238 |
Toxoplasma gondii | cathepsin B | 0.0145 | 0.1035 | 1 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0078 | 0.0455 | 0.086 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | tyrosine kinase | 0.0165 | 0.1199 | 0.3203 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0268 | 0.0155 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0078 | 0.0455 | 0.1104 |
Echinococcus multilocularis | somatostatin receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.0809 | 0.0809 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | cathepsin L | 0.0046 | 0.0181 | 0.0266 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | biogenic amine receptor | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | biogenic amine receptor | 0.009 | 0.056 | 0.1193 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0078 | 0.0456 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0165 | 0.1199 | 0.3383 |
Brugia malayi | follicle stimulating hormone receptor | 0.009 | 0.056 | 0.056 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.0429 | 0.0429 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.0226 | 0.0402 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.009 | 0.056 | 0.056 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0268 | 0.0155 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0088 | 0.0545 | 0.1382 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0056 | 0.0268 | 0.1018 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0078 | 0.0455 | 1 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Loa Loa (eye worm) | cathepsin B | 0.0145 | 0.1035 | 0.0931 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0416 | 0.3359 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0087 | 0.0537 | 0.1121 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Onchocerca volvulus | Cathepsin L homolog | 0.0078 | 0.0455 | 0.6383 |
Echinococcus multilocularis | neuropeptide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | cysteine protease | 0.0078 | 0.0455 | 0.0343 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | amine GPCR | 0.009 | 0.056 | 0.1193 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0115 | 0.0115 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.0809 | 0.0702 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.009 | 0.056 | 0.045 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0056 | 0.0268 | 0.0268 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.1108 |
Echinococcus multilocularis | neuropeptide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0298 | 0.0623 |
Echinococcus granulosus | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | neuropeptide receptor | 0.009 | 0.056 | 0.1193 |
Brugia malayi | neuropeptide F receptor | 0.009 | 0.056 | 0.056 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0165 | 0.1199 | 0.1199 |
Schistosoma mansoni | neuropeptide receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus multilocularis | 0.0051 | 0.0224 | 0.0397 | |
Brugia malayi | Serotonin receptor | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.009 | 0.056 | 0.1427 |
Plasmodium vivax | vivapain-2 | 0.0078 | 0.0455 | 0.9964 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.056 | 0.1193 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0455 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | Dopamine receptor protein 1 | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | fmrfamide receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0416 | 0.3359 | 0.3359 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.009 | 0.056 | 0.1193 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Echinococcus granulosus | cathepsin l1 | 0.0078 | 0.0455 | 0.1104 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | amine GPCR | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | neuropeptide s receptor | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0078 | 0.0455 | 0.086 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0078 | 0.0455 | 0.1104 |
Brugia malayi | Cathepsin L-like precursor | 0.0056 | 0.0268 | 0.0268 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | cathepsin b | 0.0416 | 0.3359 | 1 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Brugia malayi | AKH receptor | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | allatostatin A receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | cathepsin b | 0.0416 | 0.3359 | 1 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Loa Loa (eye worm) | G-protein coupled receptor | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.009 | 0.056 | 0.045 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.0456 | 0.4311 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | neuropeptide F receptor | 0.009 | 0.056 | 0.056 |
Giardia lamblia | Cathepsin B precursor | 0.0145 | 0.1035 | 0.5 |
Brugia malayi | Serotonin receptor | 0.009 | 0.056 | 0.056 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Brugia malayi | Probable ClpP-like protease | 0.0078 | 0.0456 | 0.0456 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.009 | 0.056 | 0.1427 |
Brugia malayi | putative neuropeptide receptor | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Plasmodium vivax | vivapain-3 | 0.0046 | 0.0181 | 0.3734 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | neuropeptides capa receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | neuropeptide Y receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0046 | 0.0181 | 0.0266 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0416 | 0.3359 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | Cathepsin L-like precursor | 0.0056 | 0.0268 | 0.0268 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0088 | 0.0545 | 0.1382 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0165 | 0.1199 | 0.3383 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Toxoplasma gondii | cathepsin CPL | 0.0078 | 0.0455 | 0.4295 |
Schistosoma mansoni | tyrosine kinase | 0.0088 | 0.0545 | 0.1146 |
Schistosoma mansoni | neuropeptide receptor | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.009 | 0.056 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0078 | 0.0455 | 0.1104 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0078 | 0.0455 | 0.0455 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | neuropeptide Y receptor | 0.009 | 0.056 | 0.1427 |
Plasmodium vivax | vivapain-1 | 0.0046 | 0.0181 | 0.3734 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0078 | 0.0456 | 0.0865 |
Echinococcus multilocularis | orexin receptor type 2 | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.009 | 0.056 | 0.1193 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0455 | 0.086 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.009 | 0.056 | 0.056 |
Brugia malayi | GnHR receptor homolog | 0.009 | 0.056 | 0.056 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | neuropeptide receptor | 0.009 | 0.056 | 0.1427 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.009 | 0.056 | 0.1427 |
Plasmodium vivax | vivapain-2 | 0.0078 | 0.0455 | 0.9964 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | RE15519p | 0.009 | 0.056 | 0.056 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Giardia lamblia | Cathepsin B precursor | 0.0145 | 0.1035 | 0.5 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0088 | 0.0545 | 0.1382 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | cathepsin b | 0.0416 | 0.3359 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | serotonin receptor | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.056 | 0.1193 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.009 | 0.056 | 0.056 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0145 | 0.1035 | 0.2688 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0456 | 0.0345 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.009 | 0.056 | 0.056 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0046 | 0.0181 | 0.0181 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0145 | 0.1035 | 0.2688 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0053 | 0.0238 | 0.044 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Brugia malayi | G-protein coupled receptor | 0.009 | 0.056 | 0.056 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0078 | 0.0455 | 0.9964 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.009 | 0.056 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0053 | 0.0238 | 0.0179 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0298 | 0.0623 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Schistosoma mansoni | histamine h1 receptor | 0.009 | 0.056 | 0.1193 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | tyrosine kinase | 0.0087 | 0.0537 | 0.1121 |
Loa Loa (eye worm) | ctsf protein | 0.0078 | 0.0455 | 0.0343 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Brugia malayi | sulfakinin receptor protein | 0.119 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.119 | 1 | 1 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0051 | 0.0226 | 0.5 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.009 | 0.056 | 0.1427 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | tyrosine kinase | 0.0053 | 0.0238 | 0.0179 |
Schistosoma mansoni | tyrosine kinase | 0.0088 | 0.0545 | 0.1146 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.0328 | 0.0463 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.009 | 0.056 | 0.1427 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0078 | 0.0456 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0165 | 0.1199 | 0.1096 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.009 | 0.056 | 0.1427 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.009 | 0.056 | 0.1427 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.009 | 0.056 | 0.1427 |
Brugia malayi | Dopamine receptor | 0.009 | 0.056 | 0.056 |
Schistosoma mansoni | amine GPCR | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | allatostatin A receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Echinococcus multilocularis | g-protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | neuropeptides capa receptor | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | tyrosine kinase | 0.0087 | 0.0537 | 0.1121 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0392 | 0.028 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.0226 | 0.0402 |
Schistosoma mansoni | opsin-like receptor | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | hypothetical protein | 0.009 | 0.056 | 0.1427 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Brugia malayi | Dopamine receptor protein 2 | 0.009 | 0.056 | 0.056 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0078 | 0.0455 | 0.1104 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.0809 | 0.0702 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 10 ng ml-1 | Compound was evaluated for the inhibition of Con A (concanavalin A) stimulated murine thymocyte mitogenesis. | ChEMBL. | 3806605 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.