Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0078 | 0.0455 | 0.1104 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | biogenic amine receptor | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | neuropeptide receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Echinococcus granulosus | orexin receptor type 2 | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | sex peptide receptor | 0.009 | 0.056 | 0.1427 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0078 | 0.0455 | 0.9964 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | TYRA-2 protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0046 | 0.0181 | 0.0181 |
Echinococcus multilocularis | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | cathepsin L | 0.0046 | 0.0181 | 0.0266 |
Echinococcus multilocularis | cysteine protease | 0.0078 | 0.0455 | 0.1104 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.009 | 0.056 | 0.045 |
Brugia malayi | Melatonin receptor type 1A | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Toxoplasma gondii | cathepsin B | 0.0145 | 0.1035 | 1 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Echinococcus granulosus | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0078 | 0.0455 | 0.086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Schistosoma mansoni | tyrosine kinase | 0.0165 | 0.1199 | 0.3203 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 1 |
Echinococcus multilocularis | sex peptide receptor | 0.009 | 0.056 | 0.1427 |
Giardia lamblia | Cathepsin B precursor | 0.0145 | 0.1035 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0078 | 0.0455 | 0.1104 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.009 | 0.056 | 0.1427 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0145 | 0.1035 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0455 | 0.086 |
Echinococcus multilocularis | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | ORL1-like opioid receptor | 0.009 | 0.056 | 0.056 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.0226 | 0.4744 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0416 | 0.3359 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0152 | 0.0037 |
Brugia malayi | Protein kinase domain containing protein | 0.0053 | 0.0238 | 0.0238 |
Echinococcus granulosus | cathepsin b | 0.0416 | 0.3359 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.009 | 0.056 | 0.1193 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | biogenic amine receptor | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | biogenic amine receptor | 0.009 | 0.056 | 0.1193 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0078 | 0.0456 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0165 | 0.1199 | 0.3383 |
Brugia malayi | follicle stimulating hormone receptor | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0268 | 0.0155 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0078 | 0.0455 | 0.1104 |
Echinococcus multilocularis | somatostatin receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.0809 | 0.0809 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | cathepsin L | 0.0046 | 0.0181 | 0.0266 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0268 | 0.0155 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0088 | 0.0545 | 0.1382 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0056 | 0.0268 | 0.1018 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0078 | 0.0455 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | cathepsin B | 0.0145 | 0.1035 | 0.0931 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.0429 | 0.0429 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.0226 | 0.0402 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.009 | 0.056 | 0.056 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Echinococcus granulosus | g-protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.009 | 0.056 | 0.056 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Echinococcus granulosus | fmrfamide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | cathepsin l1 | 0.0056 | 0.0268 | 0.0533 |
Onchocerca volvulus | Cathepsin F homolog | 0.0078 | 0.0455 | 0.6383 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | neuropeptide s receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0053 | 0.0238 | 0.044 |
Echinococcus granulosus | insulin receptor | 0.0053 | 0.0238 | 0.044 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0455 | 0.0343 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0455 | 0.086 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.009 | 0.056 | 0.1427 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0078 | 0.0455 | 1 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0268 | 0.0155 |
Brugia malayi | G-protein coupled receptor | 0.009 | 0.056 | 0.056 |
Schistosoma mansoni | adenoreceptor | 0.009 | 0.056 | 0.1193 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | amine GPCR | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0078 | 0.0455 | 0.0343 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | cysteine protease | 0.0046 | 0.0181 | 0.0266 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0056 | 0.0268 | 0.3182 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0078 | 0.0455 | 0.9964 |
Echinococcus multilocularis | insulin receptor | 0.0053 | 0.0238 | 0.044 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.5 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.1108 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0416 | 0.3359 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | opsin-like receptor | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0135 | 0.0021 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0145 | 0.1035 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0056 | 0.0268 | 0.0274 |
Loa Loa (eye worm) | fibroinase | 0.0078 | 0.0455 | 0.0343 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.009 | 0.056 | 0.1427 |
Brugia malayi | cathepsin L-like precursor | 0.0056 | 0.0268 | 0.0268 |
Loa Loa (eye worm) | hypothetical protein | 0.0416 | 0.3359 | 0.3281 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | larval opioid receptor | 0.009 | 0.056 | 0.056 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0145 | 0.1035 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0056 | 0.0268 | 0.0274 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0053 | 0.0238 | 0.0124 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Onchocerca volvulus | Cathepsin L homolog | 0.0078 | 0.0455 | 0.6383 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0078 | 0.0455 | 0.1104 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.0456 | 0.4311 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0078 | 0.0455 | 0.0343 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0046 | 0.0181 | 0.3734 |
Schistosoma mansoni | myosin xvIII | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | amine GPCR | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0056 | 0.0268 | 0.1018 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0078 | 0.0455 | 0.086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | serotonin receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | G protein-coupled receptor | 0.009 | 0.056 | 0.056 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0416 | 0.3359 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0051 | 0.0226 | 0.5 |
Plasmodium vivax | unspecified product | 0.0046 | 0.0181 | 0.3734 |
Entamoeba histolytica | cysteine protease, putative | 0.0078 | 0.0455 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0145 | 0.1035 | 0.2688 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.009 | 0.056 | 0.1193 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0053 | 0.0238 | 0.044 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.009 | 0.056 | 0.056 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0145 | 0.1035 | 0.2688 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0456 | 0.0345 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.009 | 0.056 | 0.056 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0046 | 0.0181 | 0.0181 |
Loa Loa (eye worm) | ctsf protein | 0.0078 | 0.0455 | 0.0343 |
Brugia malayi | sulfakinin receptor protein | 0.119 | 1 | 1 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Schistosoma mansoni | tyrosine kinase | 0.0087 | 0.0537 | 0.1121 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.119 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.009 | 0.056 | 0.1427 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0051 | 0.0226 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.009 | 0.056 | 0.1427 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.009 | 0.056 | 0.1193 |
Brugia malayi | G-protein coupled receptor | 0.009 | 0.056 | 0.056 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0078 | 0.0455 | 0.9964 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.009 | 0.056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0298 | 0.0623 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | tyrosine kinase | 0.0053 | 0.0238 | 0.0179 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Schistosoma mansoni | histamine h1 receptor | 0.009 | 0.056 | 0.1193 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 1 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | fmrfamide receptor | 0.009 | 0.056 | 0.1427 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | amine GPCR | 0.009 | 0.056 | 0.1193 |
Brugia malayi | Dopamine receptor | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | tyrosine kinase | 0.0053 | 0.0238 | 0.0179 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Schistosoma mansoni | tyrosine kinase | 0.0088 | 0.0545 | 0.1146 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.0328 | 0.0463 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.009 | 0.056 | 0.1427 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0078 | 0.0456 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | somatostatin receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0165 | 0.1199 | 0.1096 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.0226 | 0.0402 |
Schistosoma mansoni | tyrosine kinase | 0.0087 | 0.0537 | 0.1121 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0392 | 0.028 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | opsin-like receptor | 0.009 | 0.056 | 0.1193 |
Brugia malayi | hypothetical protein | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | hypothetical protein | 0.009 | 0.056 | 0.1427 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0078 | 0.0455 | 0.1104 |
Brugia malayi | Dopamine receptor protein 2 | 0.009 | 0.056 | 0.056 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.0809 | 0.0702 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | allatostatin A receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | neuropeptides capa receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | g-protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | neuropeptide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.0456 | 0.1108 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | g protein coupled receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0298 | 0.0623 |
Schistosoma mansoni | neuropeptide receptor | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0165 | 0.1199 | 0.1199 |
Brugia malayi | neuropeptide F receptor | 0.009 | 0.056 | 0.056 |
Brugia malayi | Serotonin receptor | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | 0.0051 | 0.0224 | 0.0397 | |
Schistosoma mansoni | neuropeptide receptor | 0.009 | 0.056 | 0.1193 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.056 | 0.1193 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.009 | 0.056 | 0.1427 |
Plasmodium vivax | vivapain-2 | 0.0078 | 0.0455 | 0.9964 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0455 | 0.086 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0416 | 0.3359 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0087 | 0.0537 | 0.1121 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | cysteine protease | 0.0078 | 0.0455 | 0.0343 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | neuropeptide receptor | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | Cathepsin L homolog | 0.0078 | 0.0455 | 0.6383 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Schistosoma mansoni | amine GPCR | 0.009 | 0.056 | 0.1193 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.009 | 0.056 | 0.045 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0115 | 0.0115 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.0809 | 0.0702 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0056 | 0.0268 | 0.0268 |
Echinococcus multilocularis | allatostatin A receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | cathepsin b | 0.0416 | 0.3359 | 1 |
Brugia malayi | AKH receptor | 0.009 | 0.056 | 0.056 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.009 | 0.056 | 0.045 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Brugia malayi | neuropeptide F receptor | 0.009 | 0.056 | 0.056 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.0456 | 0.4311 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.009 | 0.056 | 0.045 |
Giardia lamblia | Cathepsin B precursor | 0.0145 | 0.1035 | 0.5 |
Brugia malayi | Serotonin receptor | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.009 | 0.056 | 0.1427 |
Brugia malayi | Probable ClpP-like protease | 0.0078 | 0.0456 | 0.0456 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0455 | 0.0455 |
Echinococcus multilocularis | fmrfamide receptor | 0.009 | 0.056 | 0.1427 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0416 | 0.3359 | 0.3359 |
Brugia malayi | Dopamine receptor protein 1 | 0.009 | 0.056 | 0.056 |
Echinococcus granulosus | cathepsin l1 | 0.0078 | 0.0455 | 0.1104 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.009 | 0.056 | 0.1193 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.009 | 0.056 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | amine GPCR | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | neuropeptide s receptor | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Onchocerca volvulus | 0.0078 | 0.0455 | 0.6383 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0078 | 0.0455 | 0.086 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0078 | 0.0455 | 0.1104 |
Echinococcus granulosus | cathepsin b | 0.0416 | 0.3359 | 1 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0056 | 0.0268 | 0.0268 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0165 | 0.1199 | 0.3383 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Toxoplasma gondii | cathepsin CPL | 0.0078 | 0.0455 | 0.4295 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.009 | 0.056 | 0.1427 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Schistosoma mansoni | tyrosine kinase | 0.0088 | 0.0545 | 0.1146 |
Schistosoma mansoni | neuropeptide receptor | 0.009 | 0.056 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.009 | 0.056 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | neuropeptide Y receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | neuropeptides capa receptor | 0.009 | 0.056 | 0.1427 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0455 | 0.3201 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.009 | 0.056 | 0.1193 |
Plasmodium vivax | vivapain-3 | 0.0046 | 0.0181 | 0.3734 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0046 | 0.0181 | 0.0266 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0416 | 0.3359 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0056 | 0.0268 | 0.0268 |
Echinococcus granulosus | neuropeptide receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0088 | 0.0545 | 0.1382 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Giardia lamblia | Cathepsin B precursor | 0.0145 | 0.1035 | 0.5 |
Brugia malayi | RE15519p | 0.009 | 0.056 | 0.056 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0088 | 0.0545 | 0.1382 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus multilocularis | cathepsin b | 0.0416 | 0.3359 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.056 | 0.045 |
Echinococcus multilocularis | serotonin receptor | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.056 | 0.1193 |
Echinococcus granulosus | serotonin receptor | 0.009 | 0.056 | 0.1427 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0078 | 0.0455 | 0.1104 |
Echinococcus granulosus | neuropeptide Y receptor | 0.009 | 0.056 | 0.1427 |
Plasmodium vivax | vivapain-1 | 0.0046 | 0.0181 | 0.3734 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.009 | 0.056 | 0.1193 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0078 | 0.0455 | 0.0455 |
Echinococcus multilocularis | orexin receptor type 2 | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0078 | 0.0456 | 0.0865 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.009 | 0.056 | 0.1193 |
Onchocerca volvulus | 0.009 | 0.056 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0455 | 0.086 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.009 | 0.056 | 0.056 |
Echinococcus granulosus | neuropeptide receptor | 0.009 | 0.056 | 0.1427 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.009 | 0.056 | 0.1193 |
Brugia malayi | GnHR receptor homolog | 0.009 | 0.056 | 0.056 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.009 | 0.056 | 0.1427 |
Plasmodium vivax | vivapain-2 | 0.0078 | 0.0455 | 0.9964 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0455 | 0.3201 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.009 | 0.056 | 0.1427 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 100 ng ml-1 | Compound was evaluated for the inhibition of Con A (concanavalin A) stimulated murine thymocyte mitogenesis. | ChEMBL. | 3806605 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.