Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | calpain family protein 1 | 0.0063 | 0.007 | 0.0723 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0021 | 0.001 | 0.0104 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0021 | 0.001 | 0.0104 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0036 | 0.0031 | 0.0323 |
Trypanosoma brucei | calpain-like protein, putative | 0.0019 | 0.0007 | 0.0068 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0019 | 0.0006 | 0.0064 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.0048 | 0.0503 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0048 | 0.0048 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0006 | 0.0064 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0019 | 0.0007 | 0.0068 |
Trypanosoma cruzi | folylpolyglutamate synthetase | 0.0693 | 0.0962 | 1 |
Mycobacterium leprae | PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) | 0.2089 | 0.2941 | 0.2941 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.001 | 0.0104 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0095 | 0.0989 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0028 | 0.0028 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0036 | 0.0031 | 0.0031 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0019 | 0.0007 | 0.0068 |
Toxoplasma gondii | bifunctional protein FolC subfamily protein | 0.0693 | 0.0962 | 1 |
Brugia malayi | calpain 5 | 0.0019 | 0.0007 | 0.0068 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0081 | 0.0095 | 0.0989 |
Plasmodium vivax | calpain, putative | 0.0019 | 0.0007 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0006 | 0.0064 |
Brugia malayi | calpain family protein 1 | 0.0063 | 0.007 | 0.0723 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.0048 | 0.0503 |
Mycobacterium tuberculosis | Possible ligase | 0.0693 | 0.0962 | 0.0962 |
Echinococcus multilocularis | Immunoglobulin | 0.0019 | 0.0006 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0031 | 0.0323 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.001 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0006 | 0.0064 |
Loa Loa (eye worm) | TKL/RAF/RAF protein kinase | 0.0124 | 0.0155 | 0.1614 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0081 | 0.0095 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.007 | 0.0723 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0044 | 0.0043 | 0.0387 |
Chlamydia trachomatis | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 0.2089 | 0.2941 | 0.2919 |
Mycobacterium ulcerans | UDP-N-acetylmuramate--L-alanine ligase | 0.4094 | 0.5782 | 0.5782 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0044 | 0.0043 | 0.0446 |
Schistosoma mansoni | vesicular amine transporter | 0.0019 | 0.0006 | 0.0064 |
Trypanosoma brucei | antigen, putative | 0.0019 | 0.0007 | 0.0068 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0095 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0031 | 0.0323 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0048 | 0.0048 | 0.0048 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0019 | 0.0006 | 0.0064 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.0048 | 0.0503 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0007 | 0.0068 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0007 | 0.0068 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.0048 | 1 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0302 | 0.0408 | 0.4244 |
Schistosoma mansoni | Mername-AA248 (C02 family) | 0.0019 | 0.0007 | 0.0068 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0019 | 0.0006 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0031 | 0.0323 |
Echinococcus multilocularis | hypothetical protein | 0.0019 | 0.0007 | 0.0059 |
Plasmodium falciparum | dihydrofolate synthase/folylpolyglutamate synthase | 0.0693 | 0.0962 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0024 | 0.0014 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0048 | 0.0503 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0095 | 0.0989 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0019 | 0.0007 | 0.0068 |
Leishmania major | kinesin, putative | 0.0019 | 0.0007 | 0.0068 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0048 | 0.0048 | 0.0048 |
Plasmodium vivax | dihydrofolate synthase/folylpolyglutamate synthase, putative | 0.0693 | 0.0962 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0028 | 0.0028 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0019 | 0.0007 | 0.0068 |
Trypanosoma cruzi | kinesin, putative | 0.0019 | 0.0007 | 0.0068 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0036 | 0.0031 | 0.0323 |
Treponema pallidum | UDP-N-acetylmuramate--L-alanine ligase | 0.4094 | 0.5782 | 0.4025 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0021 | 0.001 | 0.0104 |
Echinococcus multilocularis | roundabout 2 | 0.0029 | 0.0021 | 0.0193 |
Echinococcus multilocularis | calpain 7 (C02 family) | 0.0019 | 0.0007 | 0.0059 |
Echinococcus granulosus | defective proboscis extension response | 0.0019 | 0.0006 | 0.0064 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0019 | 0.0006 | 0.0064 |
Mycobacterium ulcerans | folylpolyglutamate synthase protein FolC | 0.2089 | 0.2941 | 0.2941 |
Echinococcus granulosus | twitchin | 0.0023 | 0.0013 | 0.0134 |
Trypanosoma cruzi | kinesin, putative | 0.0019 | 0.0007 | 0.0068 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0282 | 0.038 | 0.3952 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0048 | 0.0048 | 0.0048 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0028 | 0.0028 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.0048 | 0.0503 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0048 | 0.0048 | 0.0048 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0007 | 0.0068 |
Entamoeba histolytica | calpain large subunit domain III containing protein | 0.0019 | 0.0007 | 0.136 |
Mycobacterium ulcerans | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase | 0.2089 | 0.2941 | 0.2941 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.0048 | 0.0503 |
Mycobacterium ulcerans | hypothetical protein | 0.0048 | 0.0048 | 0.0048 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0081 | 0.0095 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0031 | 0.0323 |
Echinococcus multilocularis | folylpolyglutamate synthase, mitochondrial | 0.0693 | 0.0962 | 0.8675 |
Echinococcus granulosus | folylpolyglutamate synthase mitochondrial | 0.0693 | 0.0962 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0048 | 0.0048 | 0.0048 |
Mycobacterium tuberculosis | Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS) | 0.2089 | 0.2941 | 0.2941 |
Schistosoma mansoni | nephrin | 0.0023 | 0.0013 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0043 | 0.0446 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.0048 | 0.0048 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0007 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0006 | 0.0064 |
Trypanosoma brucei | calpain-like protein, putative | 0.0019 | 0.0007 | 0.0068 |
Schistosoma mansoni | apoptosis regulator bax | 0.0081 | 0.0095 | 0.0989 |
Echinococcus multilocularis | calpain 5 | 0.0019 | 0.0007 | 0.0059 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0036 | 0.0031 | 0.0031 |
Echinococcus granulosus | calpain 5 | 0.0019 | 0.0007 | 0.0068 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0007 | 0.0068 |
Echinococcus multilocularis | calpain | 0.0019 | 0.0007 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0095 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0048 | 0.0503 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0006 | 0.0064 |
Echinococcus multilocularis | folylpolyglutamate synthase, mitochondrial | 0.0693 | 0.0962 | 0.8675 |
Onchocerca volvulus | Putative folylpolyglutamate synthase | 0.0693 | 0.0962 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.0048 | 0.0048 |
Loa Loa (eye worm) | FolC protein | 0.0693 | 0.0962 | 1 |
Wolbachia endosymbiont of Brugia malayi | UDP-N-acetylmuramyl pentapeptide synthase | 0.7069 | 1 | 1 |
Echinococcus multilocularis | raf serine:threonine protein kinase | 0.0217 | 0.0287 | 0.2592 |
Mycobacterium tuberculosis | Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF | 0.7069 | 1 | 1 |
Mycobacterium ulcerans | UDP-N-acetylmuramyl tripeptide synthase | 0.0693 | 0.0962 | 0.0962 |
Echinococcus granulosus | raf serine:threonine protein kinase | 0.0217 | 0.0287 | 0.2988 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.0048 | 1 |
Trypanosoma cruzi | calpain cysteine peptidase, putative | 0.0019 | 0.0007 | 0.0068 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0067 | 0.0074 | 0.0771 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0043 | 0.0446 |
Echinococcus granulosus | roundabout 2 | 0.0029 | 0.0021 | 0.0223 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0021 | 0.001 | 0.0104 |
Onchocerca volvulus | 0.0044 | 0.0043 | 0.0446 | |
Mycobacterium ulcerans | UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase | 0.4094 | 0.5782 | 0.5782 |
Chlamydia trachomatis | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase | 0.2089 | 0.2941 | 0.2919 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0019 | 0.0006 | 0.0064 |
Treponema pallidum | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (murF) | 0.7069 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | UDP-N-acetylmuramate-alanine ligase | 0.4094 | 0.5782 | 0.5333 |
Mycobacterium ulcerans | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF | 0.7069 | 1 | 1 |
Echinococcus granulosus | calpain | 0.0019 | 0.0007 | 0.0068 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0067 | 0.0074 | 0.0669 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0029 | 0.0021 | 0.0214 |
Trypanosoma brucei | calpain-like protein, putative | 0.0019 | 0.0007 | 0.0068 |
Brugia malayi | calpain 7 | 0.0019 | 0.0007 | 0.0068 |
Echinococcus multilocularis | neuroglian | 0.0023 | 0.0013 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0021 | 0.0223 |
Entamoeba histolytica | protein kinase, putative | 0.0019 | 0.0007 | 0.136 |
Echinococcus granulosus | Immunoglobulin | 0.0019 | 0.0006 | 0.0064 |
Schistosoma mansoni | calpain (C02 family) | 0.0019 | 0.0007 | 0.0068 |
Trypanosoma brucei | kinesin, putative | 0.0019 | 0.0007 | 0.0068 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0081 | 0.0095 | 0.0858 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0007 | 0.0068 |
Echinococcus granulosus | folylpolyglutamate synthase, mitochondrial | 0.0693 | 0.0962 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0048 | 0.0048 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0006 | 0.0064 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0019 | 0.0007 | 0.0068 |
Toxoplasma gondii | kringle domain-containing protein | 0.0021 | 0.001 | 0.0104 |
Treponema pallidum | UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (murE) | 0.4094 | 0.5782 | 0.4025 |
Trypanosoma brucei | folylpolyglutamate synthase, putative | 0.0693 | 0.0962 | 1 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0007 | 0.0068 |
Wolbachia endosymbiont of Brugia malayi | UDP-N-acetylmuramyl tripeptide synthase | 0.2089 | 0.2941 | 0.2189 |
Trichomonas vaginalis | dihydrofolate synthase/folylpolyglutamate synthase, putative | 0.0693 | 0.0962 | 1 |
Echinococcus granulosus | calpain A | 0.0019 | 0.0007 | 0.0068 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.0048 | 0.0048 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0021 | 0.001 | 0.0091 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.0048 | 0.0048 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0081 | 0.0095 | 0.0858 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0081 | 0.0095 | 0.0989 |
Mycobacterium leprae | ProbableUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF | 0.7069 | 1 | 1 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0019 | 0.0007 | 0.0068 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0063 | 0.007 | 0.0723 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0302 | 0.0408 | 0.4244 |
Schistosoma mansoni | folylpolyglutamate synthase | 0.0693 | 0.0962 | 1 |
Onchocerca volvulus | 0.0275 | 0.037 | 0.3842 | |
Trypanosoma cruzi | folylpolyglutamate synthase, putative | 0.0693 | 0.0962 | 1 |
Echinococcus multilocularis | Immunoglobulin | 0.0019 | 0.0006 | 0.0056 |
Echinococcus granulosus | calpain A | 0.0067 | 0.0074 | 0.0771 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.007 | 0.0723 |
Brugia malayi | Raf kinase | 0.0209 | 0.0277 | 0.2877 |
Brugia malayi | FolC bifunctional protein | 0.0693 | 0.0962 | 1 |
Leishmania major | calpain, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0007 | 0.0068 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0797 | 0.1109 | 1 |
Loa Loa (eye worm) | calpain 5 | 0.0019 | 0.0007 | 0.0068 |
Loa Loa (eye worm) | raf kinase | 0.0214 | 0.0284 | 0.2947 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0025 | 0.0015 | 0.0153 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0067 | 0.0074 | 0.0771 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0067 | 0.0074 | 0.0771 |
Echinococcus multilocularis | calpain A | 0.0067 | 0.0074 | 0.0669 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0081 | 0.0095 | 0.0989 |
Echinococcus granulosus | neuroglian | 0.0023 | 0.0013 | 0.0134 |
Brugia malayi | Kringle domain containing protein | 0.0021 | 0.001 | 0.0104 |
Chlamydia trachomatis | bifunctional UDP-N-acetylmuramate-alanine ligase/D-alanine-D-alanine ligase | 0.4094 | 0.5782 | 0.5769 |
Trypanosoma brucei | calpain-like protein, putative | 0.0019 | 0.0007 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0006 | 0.0064 |
Onchocerca volvulus | 0.0021 | 0.001 | 0.0104 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0031 | 0.0323 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0015 | 0.0153 |
Leishmania major | folylpolyglutamate synthetase | 0.0693 | 0.0962 | 1 |
Brugia malayi | calpain family protein 1 | 0.0063 | 0.007 | 0.0723 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.0048 | 0.0048 |
Schistosoma mansoni | calpain C (C02 family) | 0.0019 | 0.0007 | 0.0068 |
Schistosoma mansoni | cell adhesion molecule | 0.0025 | 0.0015 | 0.0153 |
Leishmania major | hypothetical protein, conserved | 0.0021 | 0.001 | 0.0104 |
Loa Loa (eye worm) | calpain | 0.0019 | 0.0007 | 0.0068 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0217 | 0.0287 | 0.2988 |
Onchocerca volvulus | 0.0048 | 0.0048 | 0.0503 | |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0019 | 0.0007 | 0.0068 |
Echinococcus granulosus | calpain 7 C02 family | 0.0019 | 0.0007 | 0.0068 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.0048 | 0.0503 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0021 | 0.0223 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0028 | 0.0028 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0019 | 0.0007 | 0.0068 |
Mycobacterium leprae | possible ligase | 0.0693 | 0.0962 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0048 | 0.0503 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 31 nM | Inhibition against human thrombin | ChEMBL. | 9871540 |
Ki (functional) | = 2500 nM | Concentration of the compound necessary to double the time required for clot formation induced by the addition of 4 NIH u/mL (final concentration) bovine thrombin. | ChEMBL. | 9871540 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.