TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 551.945 | Formula: C25H25ClF3N5O4
H donors: 4 H acceptors: 4 LogP: 0.94 Rotable bonds: 8
Rule of 5 violations (Lipinski): 2
SMILES: OC(=O)C(F)(F)F.NCc1cccc(c1)NC(=O)Cn1c(C)c(Cl)nc(c1=O)NC1Cc2c(C1)cccc2
InChi: 1S/C23H24ClN5O2.C2HF3O2/c1-14-21(24)28-22(27-19-10-16-6-2-3-7-17(16)11-19)23(31)29(14)13-20(30)26-18-8-4-5-15(9-18)12-25;3-2(4,5)1(6)7/h2-9,19H,10-13,25H2,1H3,(H,26,30)(H,27,28);(H,6,7)
InChiKey: JUKRBCWVZDTBBR-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	tryptase alpha/beta 1	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Brugia malayi	Trypsin family protein	tryptase alpha/beta 1	275 aa	288 aa	25.4 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	receptor protein tyrosine phosphatase n (ia2)	0.0017	0.029	0.029
Schistosoma mansoni	rgs-gaip interacting protein gipc	0.0017	0.029	0.029
Echinococcus granulosus	receptor type tyrosine protein phosphatase zeta	0.0017	0.029	0.029
Schistosoma mansoni	multidrug resistance protein	0.001	0.0086	0.0086
Brugia malayi	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Echinococcus granulosus	multidrug resistance protein 1	0.001	0.0086	0.0086
Onchocerca volvulus		0.0017	0.029	0.0569
Schistosoma mansoni	protein-tyrosine phosphatase non-receptor type nt5	0.0017	0.029	0.029
Onchocerca volvulus		0.0184	0.5102	1
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0057	0.1424	0.2668
Loa Loa (eye worm)	hypothetical protein	0.001	0.0083	0.0083
Brugia malayi	hypothetical protein	0.0017	0.029	0.029
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.001	0.0086	0.0086
Onchocerca volvulus		0.0017	0.029	0.0569
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0017	0.029	0.029
Echinococcus granulosus	Receptor type tyrosine protein phosphatase O	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Trypanosoma cruzi	hypothetical protein, conserved	0.0057	0.1424	1
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.001	0.0086	0.0086
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0017	0.029	0.029
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0017	0.029	0.029
Schistosoma mansoni	receptor protein tyrosine phosphatase	0.0017	0.029	0.029
Onchocerca volvulus		0.001	0.0086	0.0169
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Echinococcus granulosus	multidrug resistance protein 1	0.001	0.0086	0.0086
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Trichomonas vaginalis	pten, drome, putative	0.0017	0.029	0.0407
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0017	0.029	0.029
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0184	0.5102	1
Echinococcus multilocularis	multidrug resistance protein 1	0.001	0.0086	0.0086
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0017	0.029	0.029
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.001	0.0086	0.0086
Brugia malayi	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0353	1	1
Brugia malayi	Protein-tyrosine phosphatase 1	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0017	0.029	0.029
Giardia lamblia	Low molecular weight protein-tyrosine-phosphatase	0.0184	0.5102	1
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0184	0.5102	1
Echinococcus granulosus	receptor type tyrosine protein phosphatase zeta	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.001	0.0086	0.0086
Onchocerca volvulus		0.0017	0.029	0.0569
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.001	0.0086	0.0086
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Echinococcus granulosus	Receptor type tyrosine protein phosphatase O	0.0017	0.029	0.029
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0017	0.029	0.029
Schistosoma mansoni	receptor protein tyrosine phosphatase r (pcptp1)	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Leishmania major	protein-tyrosine phosphatase 1-like protein	0.0017	0.029	0.1526
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0017	0.029	0.029
Entamoeba histolytica	Pten 3-phosphoinositide phosphatase, putative	0.0017	0.029	0.0407
Onchocerca volvulus		0.0017	0.029	0.0569
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Trypanosoma cruzi	hypothetical protein, conserved	0.0057	0.1424	1
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Leishmania major	hypothetical protein, conserved	0.0057	0.1424	1
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0017	0.029	0.029
Brugia malayi	Low molecular weight phosphotyrosine protein phosphatase containing protein	0.0184	0.5102	0.5102
Echinococcus multilocularis	protein tyrosine phosphatase n9	0.0017	0.029	0.029
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0017	0.029	0.0407
Plasmodium vivax	multidrug resistance protein 1, putative	0.001	0.0086	0.5
Schistosoma mansoni	multidrug resistance protein	0.001	0.0086	0.0086
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.001	0.0086	0.0086
Echinococcus multilocularis	receptor type tyrosine protein phosphatase H	0.0017	0.029	0.029
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0353	1	1
Leishmania major	tyrosine specific protein phosphatase, putative	0.0017	0.029	0.1526
Mycobacterium ulcerans	phosphotyrosine protein phosphatase PtpA	0.0184	0.5102	1
Schistosoma mansoni	multidrug resistance protein	0.001	0.0086	0.0086
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0184	0.5102	1
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Schistosoma mansoni	receptor protein tyrosine phosphatase n (ia2)	0.0017	0.029	0.029
Trypanosoma brucei	low molecular weight protein tyrosine phosphatase, putative	0.0057	0.1424	1
Onchocerca volvulus		0.0017	0.029	0.0569
Schistosoma mansoni	non-receptor protein-tyrosine phosphatase	0.0017	0.029	0.029
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Echinococcus multilocularis	hypothetical protein	0.0017	0.029	0.029
Toxoplasma gondii	ATP-binding cassette transporter ABC.B1	0.001	0.0086	0.5
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.001	0.0086	0.0086
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0353	1	1
Onchocerca volvulus		0.0017	0.029	0.0569
Schistosoma mansoni	pcd6 interacting protein-related	0.0017	0.029	0.029
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0017	0.029	0.029
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0017	0.029	0.029
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.001	0.0086	0.0086
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.001	0.0086	0.0086
Chlamydia trachomatis	ABC transporter ATP binding protein/permease	0.001	0.0086	0.5
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0057	0.1424	0.2668
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0184	0.5102	1
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	phosphotyrosine protein phosphatase	0.0184	0.5102	0.5102
Onchocerca volvulus		0.0017	0.029	0.0569
Loa Loa (eye worm)	protein-tyrosine phosphatase 1	0.0017	0.029	0.029
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0017	0.029	0.029
Onchocerca volvulus	4.1 G protein, putative homolog	0.0017	0.029	0.0569
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Schistosoma mansoni	protein-tyrosine phosphatase n9	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Schistosoma mansoni	protein tyrosine phosphatase	0.0017	0.029	0.029
Echinococcus multilocularis		0.0017	0.029	0.029
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.001	0.0086	0.5
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Plasmodium falciparum	multidrug resistance protein 1	0.001	0.0086	0.5
Echinococcus multilocularis	ATP binding cassette sub family B	0.001	0.0083	0.0083
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0017	0.029	0.029
Schistosoma mansoni	protein tyrosine phosphatase non-receptor type nt1	0.0353	1	1
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Onchocerca volvulus		0.0017	0.029	0.0569
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0184	0.5102	1
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Brugia malayi	ABC transporter family protein	0.001	0.0086	0.0086
Loa Loa (eye worm)	protein tyrosine phosphatase	0.0017	0.029	0.029
Brugia malayi	hypothetical protein	0.0017	0.029	0.029
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0017	0.029	0.029
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0017	0.029	0.0407
Loa Loa (eye worm)	protein-tyrosine-phosphatase	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Loa Loa (eye worm)	ATP-binding cassette sub-family B member 2	0.001	0.0086	0.0086
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0184	0.5102	1
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0017	0.029	0.029
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0184	0.5102	1
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0184	0.5102	1
Schistosoma mansoni	smdr2	0.001	0.0086	0.0086
Brugia malayi	Dual specificity protein phosphatase CDC14B	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Loa Loa (eye worm)	multidrug resistance protein 3	0.001	0.0086	0.0086
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Echinococcus granulosus	multidrug resistance protein 1	0.001	0.0086	0.0086
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Mycobacterium tuberculosis	Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase)	0.0127	0.3463	1
Onchocerca volvulus		0.0017	0.029	0.0569
Echinococcus granulosus	5'partial\|ATP binding cassette sub family B	0.001	0.0083	0.0083
Onchocerca volvulus		0.0017	0.029	0.0569
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.001	0.0086	0.0086
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0017	0.029	0.029
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Brugia malayi	multidrug resistance protein 3	0.001	0.0086	0.0086
Brugia malayi	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0017	0.029	0.029
Echinococcus multilocularis	multidrug resistance protein 1	0.001	0.0086	0.0086
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Schistosoma mansoni	protein tyrosine phosphatase	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Brugia malayi	protein-tyrosine phosphatase Lar-like precursor, putative	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.0017	0.029	0.029
Onchocerca volvulus		0.0017	0.029	0.0569
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0017	0.029	0.029
Loa Loa (eye worm)	dual specificity protein phosphatase CDC14B	0.0017	0.029	0.029
Schistosoma mansoni	protein tyrosine phosphatase	0.0017	0.029	0.029
Loa Loa (eye worm)	hypothetical protein	0.001	0.0086	0.0086
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Echinococcus granulosus	protein tyrosine phosphatase n9	0.0017	0.029	0.029
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0017	0.029	0.029
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0017	0.029	0.029
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0017	0.029	0.029
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0017	0.029	0.029
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0017	0.029	0.029

Activities

Activity type	Activity value	Assay description	Source	Reference
Ki (binding)	= 970 nM	Inhibitory activity against human Tryptase beta 2 expressed in yeast cells	ChEMBL.	15341931
Ki (binding)	= 970 nM	Inhibitory activity against human Tryptase beta 2 expressed in yeast cells	ChEMBL.	15341931

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 325649