Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Leishmania major | subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Brugia malayi | plexin A | 0.0069 | 0.0047 | 0.0014 |
Echinococcus multilocularis | Peptidase S8 S53, subtilisin kexin sedolisin | 0.2793 | 0.3716 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.023 | 0.0265 | 0.5 |
Echinococcus multilocularis | neuroendocrine convertase 2 | 0.023 | 0.0265 | 0.0594 |
Echinococcus granulosus | membrane bound transcription factor site 1 | 0.023 | 0.0265 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.0265 | 0.0265 |
Schistosoma mansoni | site-1 peptidase (S08 family) | 0.023 | 0.0265 | 0.0265 |
Mycobacterium tuberculosis | Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) | 0.023 | 0.0265 | 0.5 |
Brugia malayi | Membrane-bound transcription factor site-1 protease precursor | 0.023 | 0.0265 | 0.0233 |
Plasmodium vivax | subtilisin-like protease 2, putative | 0.023 | 0.0265 | 0.5 |
Echinococcus multilocularis | membrane bound transcription factor site 1 | 0.023 | 0.0265 | 0.0594 |
Mycobacterium leprae | PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) | 0.023 | 0.0265 | 0.5 |
Echinococcus granulosus | proprotein convertase subtilisin:kexin type 5 | 0.023 | 0.0265 | 0.0594 |
Echinococcus multilocularis | 0.023 | 0.0265 | 0.0594 | |
Echinococcus granulosus | Furin 1 | 0.023 | 0.0265 | 0.0594 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0573 | 0.0727 | 0.1853 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Schistosoma mansoni | plexin | 0.0058 | 0.0033 | 0.0033 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Plasmodium vivax | subtilisin-like serine protease, putative | 0.023 | 0.0265 | 0.5 |
Mycobacterium tuberculosis | Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) | 0.023 | 0.0265 | 0.5 |
Mycobacterium leprae | PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) | 0.023 | 0.0265 | 0.5 |
Echinococcus granulosus | peptidase s8 s53 subtilisin kexin sedolisin | 0.2793 | 0.3716 | 1 |
Plasmodium falciparum | subtilisin-like protease 3 | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Schistosoma mansoni | tripeptidyl-peptidase II (S08 family) | 0.7459 | 1 | 1 |
Mycobacterium tuberculosis | Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) | 0.023 | 0.0265 | 0.5 |
Onchocerca volvulus | 0.023 | 0.0265 | 1 | |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0033 | 0.0033 |
Mycobacterium ulcerans | proline rich membrane-anchored mycosin MycP5 | 0.023 | 0.0265 | 0.5 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.023 | 0.0265 | 0.0265 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Schistosoma mansoni | site-1 peptidase (S08 family) | 0.023 | 0.0265 | 0.0265 |
Toxoplasma gondii | subtilisin SUB10 | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Plasmodium vivax | subtilisin-like protease 1 | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Toxoplasma gondii | subtilisin SUB9 | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Toxoplasma gondii | subtilisin SUB2 | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Toxoplasma gondii | subtilisin SUB1 | 0.023 | 0.0265 | 0.5 |
Mycobacterium leprae | Possible secreted protease | 0.023 | 0.0265 | 0.5 |
Echinococcus granulosus | furin | 0.023 | 0.0265 | 0.0594 |
Mycobacterium tuberculosis | Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trypanosoma cruzi | subtilisin peptidase | 0.023 | 0.0265 | 0.5 |
Loa Loa (eye worm) | proprotein convertase 2 | 0.023 | 0.0265 | 0.0265 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Echinococcus multilocularis | Furin 1 | 0.023 | 0.0265 | 0.0594 |
Schistosoma mansoni | furin-1 (S08 family) | 0.023 | 0.0265 | 0.0265 |
Trypanosoma cruzi | subtilisin-like serine peptidase, putative | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Loa Loa (eye worm) | subtilase | 0.7459 | 1 | 1 |
Echinococcus multilocularis | proprotein convertase subtilisin:kexin type 5 | 0.023 | 0.0265 | 0.0594 |
Brugia malayi | celfurPC protein | 0.023 | 0.0265 | 0.0233 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Plasmodium falciparum | subtilisin-like protease 2 | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Loa Loa (eye worm) | plexin A | 0.0069 | 0.0047 | 0.0047 |
Toxoplasma gondii | subtilisin SUB5 | 0.023 | 0.0265 | 0.5 |
Brugia malayi | Hypothetical subtilase-type proteinase F21H12.6 in chromosome II | 0.023 | 0.0265 | 0.0233 |
Toxoplasma gondii | subtilisin SUB7 | 0.023 | 0.0265 | 0.5 |
Loa Loa (eye worm) | endoprotease bli-4 | 0.023 | 0.0265 | 0.0265 |
Toxoplasma gondii | subtilisin SUB8 | 0.023 | 0.0265 | 0.5 |
Brugia malayi | proprotein convertase 2 | 0.023 | 0.0265 | 0.0233 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trypanosoma cruzi | subtilisin-like serine peptidase, putative | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0573 | 0.0727 | 0.1853 |
Brugia malayi | neuroendocrine convertase 1 precursor | 0.023 | 0.0265 | 0.0233 |
Mycobacterium ulcerans | membrane-anchored serine protease (mycosin), MycP4 | 0.023 | 0.0265 | 0.5 |
Echinococcus granulosus | neuroendocrine convertase 2 | 0.023 | 0.0265 | 0.0594 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.023 | 0.0265 | 0.0265 |
Toxoplasma gondii | subtilisin SUB6 | 0.023 | 0.0265 | 0.5 |
Toxoplasma gondii | subtilisin SUB12 | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Toxoplasma gondii | subtilisin SUB4 | 0.023 | 0.0265 | 0.5 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.023 | 0.0265 | 0.5 |
Plasmodium falciparum | subtilisin-like protease 1 | 0.023 | 0.0265 | 0.5 |
Mycobacterium ulcerans | membrane-anchored mycosin MycP3 | 0.023 | 0.0265 | 0.5 |
Trypanosoma cruzi | serine peptidase, clan SB, family S8-like protein | 0.023 | 0.0265 | 0.5 |
Brugia malayi | endoprotease bli-4 precursor | 0.023 | 0.0265 | 0.0233 |
Trypanosoma brucei | subtilisin peptidase | 0.023 | 0.0265 | 0.5 |
Toxoplasma gondii | subtilisin SUB11 | 0.023 | 0.0265 | 0.5 |
Trypanosoma brucei | serine peptidase, clan SB, family S8-like protein | 0.023 | 0.0265 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.0265 | 0.0265 |
Schistosoma mansoni | subfamily S8B non-peptidase homologue (S08 family) | 0.023 | 0.0265 | 0.0265 |
Trichomonas vaginalis | conserved hypothetical protein | 0.023 | 0.0265 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.