Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Angiotensin II receptor | Starlite/ChEMBL | References |
Rattus norvegicus | Angiotensin II receptor (AT-1) type-1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.0318 | 1 | 1 |
Echinococcus multilocularis | alpha(13)fucosyltransferase | 0.0135 | 0.0233 | 1 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.0318 | 1 | 1 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0131 | 0 | 0.5 |
Echinococcus granulosus | glycoprotein 3 alpha L fucosyltransferase | 0.0135 | 0.0233 | 1 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.0318 | 1 | 1 |
Echinococcus granulosus | alpha13fucosyltransferase | 0.0135 | 0.0233 | 1 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.0318 | 1 | 1 |
Echinococcus multilocularis | glycoprotein 3 alpha L fucosyltransferase | 0.0135 | 0.0233 | 1 |
Echinococcus multilocularis | glycoprotein 3 alpha L fucosyltransferase | 0.0135 | 0.0233 | 1 |
Echinococcus granulosus | glycoprotein 3 alpha L fucosyltransferase | 0.0135 | 0.0233 | 1 |
Echinococcus multilocularis | alpha(13)fucosyltransferase | 0.0135 | 0.0233 | 1 |
Onchocerca volvulus | Alpha 1,3 fucosyltransferase homolog | 0.0135 | 0.0233 | 0.5 |
Echinococcus multilocularis | glycoprotein 3 alpha L fucosyltransferase | 0.0135 | 0.0233 | 1 |
Echinococcus multilocularis | glycoprotein 3 alpha L fucosyltransferase | 0.0135 | 0.0233 | 1 |
Echinococcus multilocularis | glycoprotein 3 alpha L fucosyltransferase | 0.0135 | 0.0233 | 1 |
Echinococcus granulosus | glycoprotein 3 alpha L fucosyltransferase | 0.0135 | 0.0233 | 1 |
Echinococcus granulosus | glycoprotein 3 alpha L fucosyltransferase | 0.0135 | 0.0233 | 1 |
Brugia malayi | alpha1,3-fucosyltransferase homologue | 0.0318 | 1 | 0.5 |
Loa Loa (eye worm) | fucosyl transferase | 0.0318 | 1 | 1 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 2.9 uM | Inhibitory concentration that gives 50% displacement of specific binding at labeled angiotensin II type 1 receptor in rat adrenal cortical membranes. | ChEMBL. | 12593652 |
IC50 (binding) | = 2.9 uM | Ability to displace [3H]-AII (2 nM) from its specific binding sites in rat adrenal cortical microsome preparation | ChEMBL. | 2329554 |
IC50 (binding) | = 2.9 uM | Inhibitory concentration that gives 50% displacement of specific binding at labeled angiotensin II type 1 receptor in rat adrenal cortical membranes. | ChEMBL. | 12593652 |
IC50 (binding) | = 2.9 uM | Ability to displace [3H]-AII (2 nM) from its specific binding sites in rat adrenal cortical microsome preparation | ChEMBL. | 2329554 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.