Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | CYP4Cod1 | 0.0023 | 0.0265 | 0.0286 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0848 | 0.0918 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.0265 | 0.2014 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.3051 | 0.3303 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.066 | 0.0241 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0848 | 0.0848 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1014 | 0.1097 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.1418 | 0.1418 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0979 | 0.106 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.066 | 0.0241 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.066 | 0.6737 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.1079 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0248 | 0.0248 |
Leishmania major | hypothetical protein, conserved | 0.005 | 0.1079 | 0.8211 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0265 | 0.0286 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0051 | 0.111 | 0.111 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.066 | 0.1012 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0802 | 0.0802 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0746 | 0.0425 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0265 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0624 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0979 | 0.106 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0802 | 0.0802 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.2545 | 0.2756 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0746 | 0.0746 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0676 | 0.0676 |
Loa Loa (eye worm) | hypothetical protein | 0.0323 | 0.9236 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.066 | 0.1264 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0676 | 0.5147 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.066 | 0.0714 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0802 | 0.0802 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0051 | 0.111 | 0.2127 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0566 | 0.0869 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0051 | 0.111 | 0.111 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1135 | 0.1229 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0058 | 0.1314 | 0.164 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0248 | 0.0248 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0051 | 0.111 | 0.2127 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1418 | 0.1418 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0051 | 0.111 | 0.2127 |
Onchocerca volvulus | 0.0189 | 0.5221 | 0.5318 | |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0033 | 0.0547 | 0.4165 |
Brugia malayi | beta-lactamase | 0.0036 | 0.066 | 0.0714 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0189 | 0.5221 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.066 | 0.5022 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.1418 | 0.1535 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0058 | 0.1314 | 0.164 |
Schistosoma mansoni | hypothetical protein | 0.0349 | 1 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.066 | 0.0714 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0051 | 0.111 | 0.111 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0265 | 0.0286 |
Echinococcus multilocularis | expressed conserved protein | 0.0093 | 0.2365 | 0.2365 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0676 | 0.1295 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0189 | 0.5221 | 0.5652 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0545 | 0.059 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0189 | 0.5221 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.1418 | 0.1418 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0189 | 0.5221 | 0.5652 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0979 | 0.7454 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.066 | 0.5022 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0746 | 0.0425 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.005 | 0.1079 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1418 | 0.1418 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0624 | 0.0675 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0676 | 0.0732 |
Echinococcus granulosus | X box binding protein 1 | 0.0291 | 0.8272 | 0.8272 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0131 | 0.348 | 0.5338 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.066 | 0.5022 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0189 | 0.5221 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.066 | 0.066 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.066 | 0.1012 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0547 | 0.4165 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.1418 | 0.1535 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0189 | 0.5221 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.066 | 0.0714 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0047 | 0.0979 | 0.1876 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0248 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0624 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.066 | 0.0714 |
Echinococcus multilocularis | expressed protein | 0.0033 | 0.0571 | 0.0571 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0624 | 0.0675 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0746 | 0.0746 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.066 | 0.1264 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0848 | 0.0848 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0033 | 0.0571 | 0.0618 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.066 | 0.066 |
Schistosoma mansoni | hypothetical protein | 0.0349 | 1 | 1 |
Onchocerca volvulus | 0.0323 | 0.9236 | 1 | |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.066 | 0.1012 |
Echinococcus granulosus | tumor protein p63 | 0.0329 | 0.9417 | 0.9417 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0566 | 0.0869 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0051 | 0.111 | 0.8452 |
Schistosoma mansoni | rotamase | 0.0033 | 0.0571 | 0.0571 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0848 | 0.0848 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.066 | 0.0714 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0676 | 0.5 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0848 | 0.0848 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0979 | 0.1876 |
Schistosoma mansoni | hypothetical protein | 0.0291 | 0.8272 | 0.8272 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0033 | 0.0547 | 0.4927 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.066 | 0.1012 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0189 | 0.5221 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.1418 | 0.1535 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0099 | 0.2545 | 0.2545 |
Echinococcus multilocularis | tumor protein p63 | 0.0329 | 0.9417 | 0.9417 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.0979 | 0.0925 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.066 | 0.0794 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0051 | 0.111 | 0.111 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0979 | 0.106 |
Trypanosoma brucei | cytochrome P450, putative | 0.0023 | 0.0265 | 0.2014 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.066 | 0.1012 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0053 | 0.1152 | 0.1248 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0047 | 0.0979 | 0.1502 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.066 | 0.1264 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.3051 | 0.3303 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0189 | 0.5221 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0099 | 0.2545 | 0.2545 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0979 | 0.7454 |
Echinococcus multilocularis | geminin | 0.0349 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1418 | 0.1418 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0676 | 0.0276 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0047 | 0.0979 | 0.1876 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.066 | 0.5942 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0571 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.066 | 0.0714 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.1079 | 0.8211 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0676 | 0.0276 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0561 | 0.086 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.066 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.066 | 0.0714 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0058 | 0.1314 | 1 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0101 | 0.2591 | 0.2591 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0848 | 0.0918 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.0561 | 0.5724 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0142 | 0.3821 | 0.3821 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0189 | 0.5221 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0979 | 0.106 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0047 | 0.0979 | 0.1876 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0746 | 0.0746 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.005 | 0.1079 | 0.8211 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0035 | 0.0624 | 0.5 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.066 | 0.0241 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0232 | 0.6518 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0047 | 0.0979 | 0.1502 |
Onchocerca volvulus | 0.0047 | 0.0979 | 0.0372 | |
Brugia malayi | Cytochrome P450 family protein | 0.0053 | 0.1152 | 0.1248 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0848 | 0.0918 |
Onchocerca volvulus | 0.0048 | 0.1014 | 0.0413 | |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.0265 | 0.2014 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.066 | 0.6737 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.066 | 0.0241 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0189 | 0.5221 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0746 | 0.0746 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.066 | 0.1012 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0979 | 0.106 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.1418 | 0.1535 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0848 | 0.0848 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0035 | 0.0624 | 0.0957 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.066 | 0.0241 |
Mycobacterium ulcerans | hypothetical protein | 0.0047 | 0.0979 | 0.1876 |
Echinococcus multilocularis | X box binding protein 1 | 0.0291 | 0.8272 | 0.8272 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0746 | 0.0807 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.066 | 0.1012 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0802 | 0.0802 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.066 | 0.1012 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0676 | 0.0676 |
Echinococcus granulosus | expressed conserved protein | 0.0093 | 0.2365 | 0.2365 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0979 | 0.7454 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0746 | 0.0425 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.1014 | 0.1014 |
Trypanosoma brucei | low molecular weight protein tyrosine phosphatase, putative | 0.0058 | 0.1314 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0566 | 0.0869 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.066 | 0.1012 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1079 | 0.1168 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0676 | 0.0276 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0142 | 0.3821 | 0.3821 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.066 | 0.066 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.1079 | 0.8211 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.1418 | 0.1535 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0676 | 0.0732 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0979 | 0.1876 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.1079 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0676 | 0.0276 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.066 | 0.5022 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.0979 | 0.0925 |
Leishmania major | cytochrome p450-like protein | 0.0023 | 0.0265 | 0.2014 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.0979 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0624 | 0.0675 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0189 | 0.5221 | 1 |
Brugia malayi | hypothetical protein | 0.0323 | 0.9236 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.0979 | 1 |
Echinococcus granulosus | expressed protein | 0.0033 | 0.0571 | 0.0571 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0023 | 0.0265 | 0.0507 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0676 | 0.0676 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0265 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.066 | 0.0714 |
Brugia malayi | RNA binding protein | 0.0062 | 0.1418 | 0.1535 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.1029 | 0.1029 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0547 | 0.4165 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0571 | 0.0618 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.066 | 0.1264 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0099 | 0.2545 | 0.2756 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0979 | 0.1876 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0676 | 0.609 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0035 | 0.0624 | 0.1195 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1418 | 0.1418 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0051 | 0.111 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0058 | 0.1314 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0571 | 0.005 |
Leishmania major | hypothetical protein, conserved | 0.0058 | 0.1314 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0676 | 0.0676 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.066 | 0.0714 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.005 | 0.1079 | 0.9715 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0189 | 0.5221 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0676 | 0.5147 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1418 | 0.1418 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0848 | 0.0645 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0979 | 0.106 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.066 | 0.0714 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0566 | 0.0869 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.066 | 0.1012 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.3051 | 0.3303 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0047 | 0.0979 | 0.0925 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.066 | 0.1264 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.066 | 0.0714 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0099 | 0.2545 | 0.4276 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0051 | 0.111 | 0.1703 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0746 | 0.0425 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0676 | 0.5147 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0033 | 0.0547 | 0.4165 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.066 | 0.066 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0676 | 0.5147 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0047 | 0.0979 | 0.1876 |
Brugia malayi | hypothetical protein | 0.005 | 0.1079 | 0.1168 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 1.6 nM | Antimalarial activity against Plasmodium falciparum Nigerian in human erythrocytes after 48 hrs | ChEMBL. | 18004799 |
pKa | = 14.1 | Dissociation constant, pKa of the compound by potentiometric titration | ChEMBL. | 18004799 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.