Detailed information for compound 542969

Basic information

Technical information
  • TDR Targets ID: 542969
  • Name: (4E,6E,8E,10E,12E,14E,16E,18E,20E,22E,26E)-2- methoxy-2,6,10,14,19,23,27,31-octamethyl-dotr iaconta-4,6,8,10,12,14,16,18,20,22,26,30-dode caen-3-one
  • MW: 582.898 | Formula: C41H58O2
  • H donors: 0 H acceptors: 1 LogP: 13.87 Rotable bonds: 18
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(C(=O)C=CC(=CC=CC(=CC=C/C(=C/C=C/C=C(\C=C/C=C(\CC/C=C(/CCC=C(C)C)\C)/C)/C)/C)C)C)(C)C
  • InChi: 1S/C41H58O2/c1-33(2)19-14-22-36(5)25-17-28-37(6)26-15-23-34(3)20-12-13-21-35(4)24-16-27-38(7)29-18-30-39(8)31-32-40(42)41(9,10)43-11/h12-13,15-16,18-21,23-27,29-32H,14,17,22,28H2,1-11H3/b13-12+,23-15+,24-16+,29-18+,32-31+,34-20+,35-21+,36-25+,37-26+,38-27+,39-30+
  • InChiKey: ZQFURSYWJPLAJR-FZFXUSNISA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (4E,6E,8E,10E,12E,14E,16E,18E,20E,22E,26E)-2-methoxy-2,6,10,14,19,23,27,31-octamethyl-3-dotriaconta-4,6,8,10,12,14,16,18,20,22,26,30-dodecaenone
  • (4E,6E,8E,10E,12E,14E,16E,18E,20E,22E,26E)-2-methoxy-2,6,10,14,19,23,27,31-octamethyldotriaconta-4,6,8,10,12,14,16,18,20,22,26,30-dodecaen-3-one
  • spheroidenone
  • 13836-70-9
  • C15903
  • .psi.,.psi.-Carotene, 3,4-didehydro-1,2,7',8'-tetrahydro-1-methoxy-2-oxo-
  • Lycopene, 3,4-didehydro-1,2,7',8'-tetrahydro-1-methoxy-2-oxo-, all-trans-
  • LMPR01070121
  • psi,psi-Carotene, 3,4-didehydro-1,2,7',8-tetrahydro-1-methoxy-2-oxo-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.2642 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0006 0.0011 0.0049
Echinococcus multilocularis pyruvate kinase 0.0017 0.0248 0.0367
Trypanosoma brucei glucose transporter 1E 0.0034 0.0621 0.2167
Loa Loa (eye worm) hypothetical protein 0.0015 0.0219 0.0322
Leishmania major glucose transporter, lmgt2 0.0034 0.0621 0.2167
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0259 0.0903
Plasmodium falciparum glutathione reductase 0.005 0.097 0.0956
Onchocerca volvulus 0.0015 0.0217 0.3522
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0335 0.032
Leishmania major pyruvate kinase 0.0032 0.0595 0.2076
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0006 0.0016 0.0016
Echinococcus granulosus pyruvate kinase 0.0017 0.0248 0.0367
Mycobacterium tuberculosis Probable reductase 0.0113 0.2365 0.8951
Loa Loa (eye worm) RNA binding protein 0.0062 0.1236 0.1898
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0259 0.0903
Echinococcus granulosus pyruvate kinase 0.0032 0.0595 0.0905
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0335 0.0502
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.2898 0.4473
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.0611 0.093
Toxoplasma gondii protein kinase, putative 0.0307 0.6617 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0006 0.0016 0.0016
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.2365 0.8951
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0414 0.1444
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0217 0.0327
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.0612 0.0597
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.0612 0.0597
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0333 0.1262
Treponema pallidum prolyl-tRNA synthetase 0.0012 0.0134 0.4875
Plasmodium falciparum thioredoxin reductase 0.0017 0.0259 0.0243
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0006 0.0016 0.0125
Onchocerca volvulus 0.0015 0.0217 0.3522
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.0612 0.0597
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.2898 0.4473
Onchocerca volvulus 0.0015 0.0217 0.3522
Trypanosoma brucei pyruvate kinase 1, putative 0.0032 0.0595 0.2076
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0611 0.093
Trypanosoma cruzi hexose transporter, putative 0.0034 0.0621 0.2167
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0015 0.0217 0.8272
Leishmania major protein kinase, putative 0.0033 0.0611 0.2134
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0259 0.0903
Echinococcus granulosus Threonyl tRNA synthetase C 0.0006 0.0016 0.0007
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0136 0.2865 0.4422
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0611 0.093
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.1248 0.1916
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0136 0.2865 1
Schistosoma mansoni ran 0.0021 0.0335 0.0502
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0715 0.2496
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0595 0.0905
Onchocerca volvulus Putative transporter 0.0015 0.0217 0.3522
Loa Loa (eye worm) sugar transporter 0.0109 0.2266 0.3493
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0259 0.0243
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0259 1
Plasmodium falciparum hexose transporter 0.0109 0.2266 0.2253
Echinococcus granulosus solute carrier family 22 0.0015 0.0217 0.0319
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0595 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0034 0.0621 0.2167
Toxoplasma gondii sugar transporter ST2 0.0015 0.0217 0.0327
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0217 0.0756
Loa Loa (eye worm) hypothetical protein 0.0006 0.0016 0.0007
Leishmania major trypanothione reductase 0.005 0.097 0.3385
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0715 0.2496
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0217 0.0319
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0259 0.2074
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0038 0.0715 0.1081
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.1248 1
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0054
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0136 0.2865 0.9886
Trypanosoma brucei glucose transporter, putative 0.0034 0.0621 0.2167
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0136 0.2865 0.4422
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0335 0.1171
Plasmodium vivax thioredoxin reductase, putative 0.005 0.097 0.0956
Mycobacterium ulcerans pyruvate kinase 0.0032 0.0595 0.4769
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.1236 0.1898
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0414 0.0399
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Echinococcus multilocularis solute carrier family 22 0.0015 0.0217 0.0319
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0006 0.0016 0.0016
Echinococcus multilocularis calcium dependent protein kinase 0.0031 0.0566 0.086
Schistosoma mansoni hypothetical protein 0.03 0.6466 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0597 0.0907
Chlamydia trachomatis pyruvate kinase 0.0032 0.0595 1
Schistosoma mansoni hypothetical protein 0.0015 0.0219 0.0322
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0259 0.0903
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0259 0.2074
Brugia malayi Thioredoxin reductase 0.005 0.097 0.3322
Brugia malayi TAR-binding protein 0.0062 0.1236 0.4244
Echinococcus multilocularis solute carrier family 22 0.0015 0.0217 0.0319
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0414 0.6849
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0217 0.0319
Plasmodium vivax hexose transporter 0.0109 0.2266 0.2253
Giardia lamblia Prolyl-tRNA synthetase 0.0033 0.0597 1
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0259 0.0391
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0259 0.0243
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.2266 0.3493
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0136 0.2865 1
Echinococcus multilocularis pyruvate kinase 0.0032 0.0595 0.0905
Brugia malayi Pyruvate kinase, M2 isozyme 0.0032 0.0595 0.2022
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.0097 0.0299
Entamoeba histolytica hypothetical protein 0.0024 0.0414 0.141
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0948 0.3244
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0217 0.0956
Echinococcus multilocularis solute carrier family 22 0.0015 0.0217 0.0319
Giardia lamblia Pyruvate kinase 0.0032 0.0595 0.997
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0335 0.0507
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0217 0.1737
Echinococcus granulosus geminin 0.0166 0.3532 0.5454
Loa Loa (eye worm) glutathione reductase 0.005 0.097 0.1486
Onchocerca volvulus 0.0015 0.0217 0.3522
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.097 0.3672
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0217 0.0956
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0715 0.2496
Echinococcus granulosus General substrate transporter 0.0093 0.193 0.2974
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0136 0.2865 1
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0219 0.072
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0259 0.1142
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0136 0.2865 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0219 0.072
Onchocerca volvulus 0.0015 0.0217 0.3522
Trypanosoma brucei glucose transporter, putative 0.0034 0.0621 0.2167
Loa Loa (eye worm) hypothetical protein 0.0026 0.0463 0.07
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0259 0.0903
Echinococcus multilocularis tar DNA binding protein 0.0062 0.1236 0.1898
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.2898 0.4473
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0062 0.1248 0.4722
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Giardia lamblia Pyruvate kinase 0.0017 0.0248 0.3994
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0259 0.0243
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0259 0.1142
Plasmodium falciparum glutathione reductase 0.0017 0.0259 0.0243
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0109 0.2266 0.3493
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0033 0.0597 0.2052
Leishmania major glucose transporter, lmgt1 0.0034 0.0621 0.2167
Entamoeba histolytica Ran family GTPase 0.0021 0.0335 0.1136
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0611 0.093
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0414 0.0625
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0217 0.0756
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0414 0.3315
Echinococcus granulosus snurportin 1 0.03 0.6466 1
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0109 0.2266 0.3493
Echinococcus multilocularis GPCR, family 2 0.0015 0.0219 0.0322
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0007 0.0044 0.0153
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0217 0.0319
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0006 0.0016 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0062 0.1236 0.1898
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0217 0.0956
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0219 0.0322
Schistosoma mansoni tar DNA-binding protein 0.0062 0.1236 0.1898
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0006 0.0011 0.0049
Toxoplasma gondii pyruvate kinase PyK1 0.0032 0.0595 0.0899
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0006 0.0011 0.0049
Schistosoma mansoni protein kinase 0.0033 0.0611 0.093
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0414 0.3315
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0217 0.0756
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0006 0.0011 0.0049
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Brugia malayi pyruvate kinase 0.0007 0.0032 0.0072
Leishmania major glucose transporter/membrane transporter D2, putative 0.0034 0.0621 0.2167
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.0612 0.0925
Schistosoma mansoni tar DNA-binding protein 0.0062 0.1236 0.1898
Schistosoma mansoni importin beta-1 0.0028 0.0498 0.0755
Brugia malayi Sugar transporter family protein 0.0015 0.0217 0.0712
Entamoeba histolytica protein kinase, putative 0.0033 0.0611 0.2104
Echinococcus multilocularis General substrate transporter 0.0093 0.193 0.2974
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Plasmodium falciparum proline--tRNA ligase 0.0038 0.0715 0.0701
Chlamydia trachomatis proline--tRNA ligase 0.0012 0.0134 0.2046
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0259 0.4183
Trypanosoma brucei glucose transporter, putative 0.0034 0.0621 0.2167
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0382 0.1684
Onchocerca volvulus 0.0015 0.0217 0.3522
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.2642 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.0612 0.0597
Loa Loa (eye worm) hypothetical protein 0.0023 0.0379 0.057
Mycobacterium leprae Probable pyruvate kinase PykA 0.0032 0.0595 0.2252
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0259 0.0384
Plasmodium falciparum mitogen-activated protein kinase 2 0.0175 0.3734 0.3724
Plasmodium falciparum protein kinase 7 0.0307 0.6617 0.6612
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.2266 0.3493
Schistosoma mansoni glucose transport protein 0.0109 0.2266 0.3493
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.2266 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0379 0.1289
Brugia malayi RNA, U transporter 1 0.008 0.1635 0.5626
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0259 0.0903
Loa Loa (eye worm) hypothetical protein 0.0033 0.0597 0.0907
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0414 0.1444
Loa Loa (eye worm) hypothetical protein 0.0033 0.0597 0.0907
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0006 0.0016 0.0059
Plasmodium vivax pyruvate kinase, putative 0.0032 0.0595 0.058
Echinococcus multilocularis glycyl tRNA synthetase 0.0006 0.0016 0.0007
Schistosoma mansoni pyruvate kinase 0.0032 0.0595 0.0905
Trypanosoma brucei trypanothione reductase 0.005 0.097 0.3385
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0382 0.1332
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0006 0.0016 0.0125
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0595 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0611 0.093
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Brugia malayi RNA binding protein 0.0062 0.1236 0.4244
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0137 0.2898 0.4473
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0259 0.0391
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0217 0.0319
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0006 0.0011 0.0049
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0033 0.0597 0.2259
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0006 0.0016 0.0059
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0259 0.4196
Trypanosoma brucei sugar transporter, putative 0.0015 0.0217 0.0756
Loa Loa (eye worm) hypothetical protein 0.0049 0.0948 0.1451
Onchocerca volvulus 0.0015 0.0217 0.3522
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0259 1
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0217 0.0756
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0259 0.0903
Loa Loa (eye worm) hypothetical protein 0.0024 0.0414 0.0624
Echinococcus granulosus pyruvate kinase 0.0032 0.0595 0.0905
Schistosoma mansoni glucose transport protein 0.0109 0.2266 0.3493
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0611 0.093
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0498 0.1739
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trichomonas vaginalis ran, putative 0.0021 0.0335 0.148
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0054
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0006 0.0016 0.0024
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.0611 0.2134
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0217 0.0956
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0333 0.1262
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.2266 0.3493
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0414 0.1826
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Treponema pallidum NADH oxidase 0.0017 0.0259 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0611 0.093
Schistosoma mansoni protein kinase 0.0033 0.0611 0.093
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0379 0.057
Plasmodium falciparum importin beta, putative 0.0028 0.0498 0.0483
Loa Loa (eye worm) TAR-binding protein 0.0062 0.1236 0.1898
Onchocerca volvulus 0.0015 0.0217 0.3522
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0136 0.2865 0.4422
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0109 0.2266 0.3493
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0259 0.0903
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0414 0.0624
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.2365 0.8951
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.0612 0.0597
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0414 0.0399
Trypanosoma cruzi hexose transporter 0.0034 0.0621 0.2167
Echinococcus granulosus tar DNA binding protein 0.0062 0.1236 0.1898
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0259 0.0979
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trypanosoma brucei glucose transporter, putative 0.0034 0.0621 0.2167
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0006 0.0016 0.0007
Trichomonas vaginalis sugar transporter, putative 0.0034 0.0621 0.274
Echinococcus granulosus pyruvate kinase 0.0017 0.0248 0.0367
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.2642 1
Brugia malayi Sugar transporter family protein 0.0109 0.2266 0.7809
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.2365 0.8951
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0217 0.0756
Trichomonas vaginalis glucose transporter, putative 0.0034 0.0621 0.274
Leishmania major threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0054
Loa Loa (eye worm) sugar transporter 0.0015 0.0217 0.0319
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0335 0.1123
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0136 0.2865 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0033 0.0597 0.2634
Brugia malayi hypothetical protein 0.0015 0.0217 0.0712
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0033 0.0597 0.2028
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.6466 1
Toxoplasma gondii facilitative glucose transporter GT1 0.0109 0.2266 0.3424
Brugia malayi Pyruvate kinase, muscle isozyme 0.0032 0.0595 0.2022
Trypanosoma brucei THT1 - hexose transporter, putative 0.0034 0.0621 0.2167
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0414 0.0624
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0219 0.0322
Schistosoma mansoni tar DNA-binding protein 0.0062 0.1236 0.1898
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0069
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0597 0.0907
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0021 0.0333 0.1262
Brugia malayi hypothetical protein 0.0015 0.0217 0.0712
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0335 0.5503
Schistosoma mansoni tar DNA-binding protein 0.0062 0.1236 0.1898
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.1248 1
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0217 0.0319
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0217 0.0712
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0217 0.0956
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0033 0.0597 0.0907
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0006 0.0011 0.0049
Onchocerca volvulus 0.0015 0.0217 0.3522
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.1248 0.1916
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0259 0.0384
Echinococcus granulosus glycyl tRNA synthetase 0.0006 0.0016 0.0007
Onchocerca volvulus 0.0015 0.0217 0.3522
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0006 0.0011 0.0049
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0217 0.1737
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0217 0.1737
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0032 0.0595 0.2252
Schistosoma mansoni pyruvate kinase 0.0017 0.0248 0.0367
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trypanosoma brucei glucose transporter 2A 0.0034 0.0621 0.2167
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0248 0.0232
Trypanosoma brucei pyruvate kinase 1 0.0032 0.0595 0.2076
Schistosoma mansoni sugar transporter 0.0015 0.0217 0.0319
Entamoeba histolytica protein kinase, putative 0.0033 0.0611 0.2104
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0175 0.3734 0.5643
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0259 0.0903
Echinococcus multilocularis snurportin 1 0.03 0.6466 1
Plasmodium falciparum thioredoxin reductase 0.005 0.097 0.0956
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.061 0.2076
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0217 0.0201
Schistosoma mansoni hypothetical protein 0.0015 0.0219 0.0322
Trypanosoma brucei glucose transporter, putative 0.0034 0.0621 0.2167
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0259 0.0903
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0498 0.1739
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0219 0.0322
Loa Loa (eye worm) hypothetical protein 0.0033 0.0611 0.093
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0611 0.093
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0595 0.2076
Schistosoma mansoni glucose transport protein 0.0109 0.2266 0.3493
Schistosoma mansoni protein kinase 0.0033 0.0611 0.093
Echinococcus granulosus calcium dependent protein kinase 0.0031 0.0566 0.086
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0033 0.0597 0.0907
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.1236 0.4244
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.0612 0.0925
Echinococcus multilocularis pyruvate kinase 0.0017 0.0248 0.0367
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.1156 0.1773
Schistosoma mansoni pyruvate kinase 0.0032 0.0595 0.0905
Plasmodium vivax glutathione reductase, putative 0.005 0.097 0.0956
Leishmania major hypothetical protein, conserved 0.0015 0.0217 0.0756
Brugia malayi major facilitator superfamily protein 0.0015 0.0217 0.0712
Toxoplasma gondii sugar transporter ST3 0.0015 0.0217 0.0327
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0595 0.2076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Loa Loa (eye worm) hypothetical protein 0.0033 0.061 0.0929
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0033 0.0597 0.2028
Schistosoma mansoni ran 0.0021 0.0335 0.0502
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0034 0.0621 0.274
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0259 0.2074
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.0611 0.093
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0217 0.0712
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0498 0.0753
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0595 0.0905
Echinococcus multilocularis solute carrier family 22 0.0015 0.0217 0.0319
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0054
Echinococcus multilocularis pyruvate kinase 0.0026 0.0445 0.0672
Brugia malayi Cam kinase protein 1 0.0033 0.0611 0.208
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.2898 0.4473
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0259 0.0903
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0335 0.1171
Onchocerca volvulus 0.0015 0.0217 0.3522
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.1248 0.4283
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0595 0.2626
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0136 0.2865 0.4422
Schistosoma mansoni glucose transporter 0.0015 0.0217 0.0319
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0611 0.2699
Plasmodium vivax CDK-related protein kinase 6, putative 0.0461 1 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0159 0.0511
Echinococcus multilocularis pyruvate kinase 0.0017 0.0248 0.0367
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0498 0.0755
Plasmodium vivax sugar transporter, putative 0.0015 0.0217 0.0201
Schistosoma mansoni hypothetical protein 0.0166 0.3532 0.5454
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0621 0.274
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.0414 0.687
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0382 0.1684
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0414 0.1566
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0948 0.3244
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0006 0.0016 0.0007
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0062 0.1248 0.1916
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.097 0.1486
Brugia malayi glycyl-tRNA synthetase 0.0006 0.0016 0.0016
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0348 0.1536
Leishmania major pyruvate kinase 0.0032 0.0595 0.2076
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0217 0.0319
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0175 0.0254
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.0611 0.208
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0219 0.0322
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Brugia malayi glutathione reductase 0.005 0.097 0.3322
Echinococcus granulosus solute carrier family 22 0.0015 0.0217 0.0319
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.2898 0.4473
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.2898 0.4473
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0335 0.032
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0715 0.2496
Trypanosoma cruzi hexose transporter, putative 0.0034 0.0621 0.2167
Onchocerca volvulus 0.0015 0.0217 0.3522
Echinococcus granulosus pyruvate kinase 0.0017 0.0248 0.0367
Onchocerca volvulus 0.0015 0.0217 0.3522
Echinococcus granulosus GPCR family 2 0.0015 0.0219 0.0322
Schistosoma mansoni hypothetical protein 0.0033 0.061 0.0929
Leishmania major GTP-binding protein, putative 0.0021 0.0335 0.1171
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.097 0.1486
Leishmania major importin beta-1 subunit, putative 0.0023 0.0382 0.1332
Echinococcus granulosus transcription factor Dp 1 0.0079 0.1609 0.2475
Echinococcus multilocularis geminin 0.0166 0.3532 0.5454
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0259 0.0903
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0259 0.0903
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.0611 0.093
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0217 0.0956
Plasmodium vivax importin-beta 2, putative 0.0028 0.0498 0.0483
Trypanosoma cruzi hexose transporter, putative 0.0034 0.0621 0.2167
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.2898 0.4473
Trypanosoma brucei glucose transporter, putative 0.0034 0.0621 0.2167
Schistosoma mansoni sugar transporter 0.0015 0.0217 0.0319
Onchocerca volvulus 0.0015 0.0217 0.3522
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0109 0.2266 0.3493
Toxoplasma gondii thioredoxin reductase 0.005 0.097 0.1466
Echinococcus granulosus solute carrier family 22 0.0015 0.0217 0.0319
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0414 0.1444
Schistosoma mansoni sugar transporter 0.0015 0.0217 0.0319
Schistosoma mansoni hypothetical protein 0.0015 0.0219 0.0322
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0414 0.0624
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Schistosoma mansoni hypothetical protein 0.0166 0.3532 0.5454
Brugia malayi pyruvate kinase, muscle isozyme 0.0007 0.0032 0.0072
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0382 0.1684
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.0612 0.0597
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0217 0.0712
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.2642 1
Onchocerca volvulus 0.0015 0.0217 0.3522
Brugia malayi Importin beta-1 subunit 0.0028 0.0498 0.1687
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0335 0.0502
Loa Loa (eye worm) hypothetical protein 0.0015 0.0217 0.0319
Echinococcus multilocularis transcription factor Dp 1 0.0079 0.1609 0.2475
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0248 0.0374
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.2365 0.8951
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0137 0.2898 1
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0175 0.3734 0.3724
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0217 0.0319
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0259 0.0384
Plasmodium falciparum pyruvate kinase 0.0032 0.0595 0.058
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0015 0.0217 0.082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0259 0.0903
Giardia lamblia Sugar-proton symporter 0.0015 0.0217 0.346
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0259 0.0903
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.2365 0.8951
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0006 0.0011 0.0049
Mycobacterium ulcerans sugar transporter 0.0015 0.0217 0.1737
Loa Loa (eye worm) pyruvate kinase 0.0007 0.0032 0.0032
Schistosoma mansoni sugar transporter 0.0015 0.0217 0.0319
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0016
Toxoplasma gondii sugar transporter ST1 0.0015 0.0217 0.0327
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0248 0.0232
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.097 0.3385
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.0612 0.0925
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0217 0.0956
Brugia malayi hypothetical protein 0.0015 0.0217 0.0712
Echinococcus granulosus importin subunit beta 1 0.0028 0.0498 0.0755
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.0612 0.0597
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.0612 0.0597
Loa Loa (eye worm) hypothetical protein 0.0028 0.0498 0.0755
Toxoplasma gondii glycyl-tRNA synthetase 0.0006 0.0016 0.0024
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0062 0.1248 0.4354
Plasmodium vivax proline--tRNA ligase, putative 0.0038 0.0715 0.0701
Trypanosoma brucei glucose transporter, putative 0.0034 0.0621 0.2167
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0006 0.0016 0.0054
Loa Loa (eye worm) thioredoxin reductase 0.005 0.097 0.1486
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0219 0.0322
Schistosoma mansoni hypothetical protein 0.0015 0.0219 0.0322
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0259 0.0903
Brugia malayi major facilitator superfamily protein 0.0015 0.0217 0.0712
Leishmania major glucose transporter, lmgt3 0.0034 0.0621 0.2167
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0621 0.274
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0015 0.0217 0.082
Trypanosoma brucei glucose transporter, putative 0.0034 0.0621 0.2167
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0948 0.1451
Schistosoma mansoni glycyl-tRNA synthetase 0.0006 0.0016 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0217 0.0956
Giardia lamblia Hexose transporter 0.0015 0.0217 0.346
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0259 0.0243
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0595 0.2626
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0286 0.0997
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0414 0.1394
Trypanosoma brucei THT1 - hexose transporter, putative 0.0034 0.0621 0.2167
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0414 0.0624
Echinococcus multilocularis pyruvate kinase 0.0032 0.0595 0.0905
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0034 0.0621 0.274
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0611 0.093
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.2365 0.8951
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.0612 0.0597
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0715 0.2496
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0259 0.0858
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0109 0.2266 0.3493
Trichomonas vaginalis glucose transporter, putative 0.0034 0.0621 0.274
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0595 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0159 0.0511
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0335 0.1171
Echinococcus granulosus solute carrier family 22 0.0015 0.0217 0.0319
Brugia malayi Sugar transporter family protein 0.0015 0.0217 0.0712
Schistosoma mansoni hypothetical protein 0.0109 0.2266 0.3493
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0595 0.0905
Onchocerca volvulus 0.0015 0.0217 0.3522
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0335 0.0502
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0259 0.0903
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0012 0.0134 0.1075
Entamoeba histolytica hypothetical protein 0.0023 0.0382 0.1298
Loa Loa (eye worm) hypothetical protein 0.0032 0.0595 0.0905

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.