Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0142 | 0.034 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0068 | 0.0185 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0083 | 0.0224 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0068 | 0.0185 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0307 | 0.0828 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0068 | 0.0141 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0068 | 0.0141 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0403 | 0.2189 | 0.5903 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0239 | 0.0643 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0083 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0233 | 0.1256 | 0.1247 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0016 | 0.0044 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0403 | 0.2189 | 0.5885 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0083 | 0.0181 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0068 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0174 | 0.0164 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0083 | 0.5 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0083 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0083 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0083 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0083 | 0.0073 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0142 | 0.0382 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.005 | 0.55 |
Loa Loa (eye worm) | NNMT/PNMT/TEMT family protein | 0.1825 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0233 | 0.1256 | 0.1247 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0068 | 0.0058 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0239 | 0.0643 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.005 | 0.55 |
Echinococcus multilocularis | muscleblind protein | 0.0305 | 0.1652 | 0.4428 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.005 | 0.55 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.005 | 0.55 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0142 | 0.0382 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0233 | 0.1256 | 0.3358 |
Onchocerca volvulus | 0.0047 | 0.0239 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.1825 | 1 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0083 | 0.0073 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0083 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0305 | 0.1652 | 0.1643 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0083 | 0.0073 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0305 | 0.1652 | 0.4428 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0174 | 0.0469 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0068 | 0.0058 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0068 | 0.0141 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0133 | 0.0123 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0083 | 1 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0025 | 0.0015 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0068 | 0.0141 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0083 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0133 | 0.0359 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0679 | 0.3709 | 1 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0142 | 0.034 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0233 | 0.1256 | 0.3358 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0083 | 0.0181 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0083 | 0.0073 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0068 | 0.0185 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0006 | 0.001 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0265 | 0.0254 |
Brugia malayi | Muscleblind-like protein | 0.0305 | 0.1652 | 0.1643 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0026 | 0.0026 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0083 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0083 | 1 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0006 | 0.001 | 0.5 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0026 | 0.0015 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0083 | 0.5 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0239 | 0.0228 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0068 | 0.0185 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0265 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0265 | 0.0254 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1825 | 1 | 1 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0006 | 0.001 | 0.0028 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0026 | 0.0026 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0679 | 0.3709 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0068 | 0.0058 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0083 | 0.0181 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0679 | 0.3709 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0133 | 0.0123 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.005 | 0.55 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0083 | 0.0181 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0083 | 0.0224 |
Echinococcus granulosus | muscleblind protein | 0.0305 | 0.1652 | 0.4428 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0272 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0068 | 0.0141 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0083 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0068 | 0.0058 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0083 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0083 | 0.0224 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0083 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0174 | 0.0164 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0305 | 0.1652 | 0.1643 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0265 | 0.0254 |
Echinococcus granulosus | dnaJ subfamily B | 0.0403 | 0.2189 | 0.5885 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0083 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0083 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0083 | 0.0181 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
3 literature references were collected for this gene.