Detailed information for compound 565061

Basic information

Technical information
  • TDR Targets ID: 565061
  • Name: platyphylline
  • MW: 337.411 | Formula: C18H27NO5
  • H donors: 1 H acceptors: 3 LogP: 1.93 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: C/C=C\1/C[C@@H](C)[C@@](C)(O)C(=O)OC[C@@H]2[C@@H]3[C@H](OC1=O)CCN3CC2
  • InChi: 1S/C18H27NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4,11,13-15,22H,5-10H2,1-3H3/b12-4-/t11-,13-,14-,15-,18-/m1/s1
  • InChiKey: BTHCJHQOYFUIMG-REYNEDSXSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (1-alpha)-1,2-Dihydro-12-hydroxysenecionan-11,16-dione
  • EINECS 207-558-6
  • Platiphillin
  • Platiphyllin
  • Senecionan-11,16-dione, 1,2-dihydro-12-hydroxy-, (1-alpha)-
  • STOCK1N-54408
  • C10363

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0066 0.0218
Entamoeba histolytica hypothetical protein 0.0023 0.012 0.2114
Echinococcus granulosus importin subunit beta 1 0.0028 0.0159 0.0545
Echinococcus multilocularis para nitrobenzyl esterase 0.0012 0.0039 0.0126
Mycobacterium ulcerans carboxylesterase, LipT 0.0012 0.0039 0.0947
Onchocerca volvulus 0.001 0.003 0.0027
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0066 0.0233
Schistosoma mansoni hypothetical protein 0.03 0.2151 0.7483
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0105 0.0475
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0122 0.2136
Schistosoma mansoni ran 0.0021 0.0105 0.0356
Loa Loa (eye worm) hypothetical protein 0.0012 0.0044 0.0189
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0159 0.0581
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.0168
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0105 0.0379
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0122 0.3115
Schistosoma mansoni importin beta-1 0.0028 0.0159 0.0545
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0384 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0079 0.0355
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0066 0.1644
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0066 0.0233
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0066 0.0233
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0122 0.3115
Giardia lamblia Telomerase catalytic subunit 0.0375 0.2698 1
Schistosoma mansoni intermediate filament proteins 0.0026 0.0147 0.0503
Brugia malayi isocitrate dehydrogenase 0.0015 0.0066 0.0086
Loa Loa (eye worm) hypothetical protein 0.0015 0.0065 0.0291
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0065 0.0291
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.0168
Schistosoma mansoni hypothetical protein 0.0205 0.1453 0.505
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0147 0.0672
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0012 0.0039 0.0947
Loa Loa (eye worm) carboxylesterase 0.0069 0.046 0.2125
Loa Loa (eye worm) hypothetical protein 0.0069 0.046 0.2125
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0079 0.0283
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0105 0.0379
Trypanosoma brucei telomerase reverse transcriptase 0.0375 0.2698 1
Schistosoma mansoni lamin 0.0026 0.0147 0.0503
Schistosoma mansoni hypothetical protein 0.0033 0.0195 0.067
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0066 0.0218
Echinococcus granulosus BC026374 protein S09 family 0.0012 0.0039 0.0126
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0384 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0144 0.0656
Echinococcus multilocularis lamin dm0 0.0026 0.0147 0.0503
Onchocerca volvulus 0.0023 0.0122 0.0119
Echinococcus granulosus para nitrobenzyl esterase 0.0012 0.0039 0.0126
Plasmodium vivax importin-beta 2, putative 0.0028 0.0159 0.0581
Onchocerca volvulus 0.0012 0.0039 0.0036
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0003 0.0242
Onchocerca volvulus 0.0146 0.1025 0.1023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0122 0.0553
Loa Loa (eye worm) hypothetical protein 0.0023 0.0122 0.0553
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0147 0.0672
Plasmodium falciparum telomerase reverse transcriptase 0.0375 0.2698 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0384 0.1328
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0122 0.3115
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0072 0.182
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.046 0.1591
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0105 0.0379
Schistosoma mansoni cpg binding protein 0.003 0.017 0.0583
Echinococcus multilocularis snurportin 1 0.03 0.2151 0.7483
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0072 0.182
Loa Loa (eye worm) hypothetical protein 0.0146 0.1025 0.4759
Brugia malayi Carboxylesterase family protein 0.0012 0.0039 0.005
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0012 0.0039 0.324
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0079 0.2
Plasmodium vivax telomerase reverse transcriptase, putative 0.0375 0.2698 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0105 0.0141
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0122 0.0441
Schistosoma mansoni hypothetical protein 0.0399 0.2874 1
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0066 0.0086
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0307 0.0419
Echinococcus granulosus neuroligin 0.0012 0.0039 0.0126
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0072 0.182
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.012 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0066 0.0218
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0065 0.0218
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0017 0.0049
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0066 0.0233
Toxoplasma gondii RNA-directed DNA polymerase 0.0375 0.2698 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0039 0.0126
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0122 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.0168
Echinococcus multilocularis acetylcholinesterase 0.0069 0.046 0.1591
Echinococcus multilocularis geminin 0.0205 0.1453 0.505
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0004 0.0005
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0105 0.0379
Echinococcus granulosus cpg binding protein 0.003 0.017 0.0583
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0079 0.0283
Loa Loa (eye worm) hypothetical protein 0.0033 0.0195 0.0895
Entamoeba histolytica Ran family GTPase 0.0021 0.0105 0.1836
Leishmania major telomerase reverse transcriptase, putative 0.0375 0.2698 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0066 0.0218
Loa Loa (eye worm) carboxylesterase 0.0012 0.0039 0.0168
Loa Loa (eye worm) hypothetical protein 0.0013 0.0047 0.0206
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0079 0.5
Brugia malayi RNA, U transporter 1 0.008 0.0539 0.0739
Onchocerca volvulus 0.0026 0.0147 0.0145
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.0168
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0012 0.0039 0.0126
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0307 0.1416
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0122 0.3115
Onchocerca volvulus 0.0028 0.0159 0.0156
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0375 0.2698 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0004 0.0005
Echinococcus multilocularis cpg binding protein 0.003 0.017 0.0583
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0122 0.2136
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0105 0.0379
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0122 0.0441
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0159 0.0725
Brugia malayi Carboxylesterase family protein 0.0012 0.0039 0.005
Echinococcus multilocularis neuroligin 0.0012 0.0039 0.0126
Brugia malayi Carboxylesterase family protein 0.0012 0.0039 0.005
Schistosoma mansoni ran 0.0021 0.0105 0.0356
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0066 0.0218
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0384 1
Brugia malayi STAT protein, DNA binding domain containing protein 0.0292 0.2091 0.2878
Mycobacterium tuberculosis Carboxylesterase LipT 0.0012 0.0039 0.0947
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0003 0.0242
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0384 0.1328
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0159 0.0545
Onchocerca volvulus 0.0026 0.0147 0.0145
Trichomonas vaginalis spcc417.12 protein, putative 0.0012 0.0039 0.324
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.0218
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0388 0.1343
Brugia malayi Importin beta-1 subunit 0.0028 0.0159 0.0216
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.012 1
Trichomonas vaginalis ran, putative 0.0021 0.0105 0.872
Echinococcus multilocularis BC026374 protein (S09 family) 0.0012 0.0039 0.0126
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0012 0.0039 0.0947
Schistosoma mansoni cpg binding protein 0.003 0.017 0.0583
Leishmania major importin beta-1 subunit, putative 0.0023 0.012 0.0436
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0122 0.0441
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0384 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.0159 0.0215
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0065 0.0086
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0065 0.0218
Echinococcus multilocularis acetylcholinesterase 0.0069 0.046 0.1591
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0384 0.1415
Loa Loa (eye worm) acetylcholinesterase 1 0.0069 0.046 0.2125
Onchocerca volvulus 0.0012 0.0039 0.0036
Echinococcus granulosus lamin 0.0026 0.0147 0.0503
Loa Loa (eye worm) hypothetical protein 0.0069 0.046 0.2125
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0066 0.0233
Schistosoma mansoni BC026374 protein (S09 family) 0.0012 0.0039 0.0126
Schistosoma mansoni gliotactin 0.0012 0.0039 0.0126
Loa Loa (eye worm) hypothetical protein 0.0083 0.0559 0.2589
Loa Loa (eye worm) hypothetical protein 0.0028 0.0159 0.0728
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0004 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0122 0.3115
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0017 0.0065
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0159 0.0581
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.0168
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0122 0.3115
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0016 0.0018
Echinococcus multilocularis carboxylesterase 5A 0.0069 0.046 0.1591
Loa Loa (eye worm) carboxylesterase 0.0012 0.0039 0.0168
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0012 0.0039 0.0126
Loa Loa (eye worm) hypothetical protein 0.0023 0.0122 0.0553
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0122 0.0164
Echinococcus granulosus snurportin 1 0.03 0.2151 0.7483
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0147 0.0199
Brugia malayi Carboxylesterase family protein 0.0069 0.046 0.063
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0342 0.1258
Schistosoma mansoni cpg binding protein 0.0028 0.0159 0.0542
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0122 0.3115
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0159 0.0581
Brugia malayi Carboxylesterase family protein 0.0069 0.046 0.063
Echinococcus granulosus acetylcholinesterase 0.0069 0.046 0.1591
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0122 0.0164
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0307 0.0419
Onchocerca volvulus 0.0012 0.0039 0.0036
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0066 0.0218
Brugia malayi hypothetical protein 0.0012 0.0039 0.005
Leishmania major GTP-binding protein, putative 0.0021 0.0105 0.0379
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.012 0.0436
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0065 0.0086
Loa Loa (eye worm) hypothetical protein 0.0012 0.0044 0.0189
Schistosoma mansoni neuroligin 3 (S09 family) 0.0012 0.0039 0.0126
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0039 0.0126
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0057 0.0075
Loa Loa (eye worm) STAT protein 0.0292 0.2091 0.9717
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0384 0.1415
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0122 0.0164
Schistosoma mansoni acetylcholinesterase 0.0012 0.0039 0.0126
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0066 0.0233
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0004 0.0005
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0066 0.0292
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.0218
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0066 0.0218
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0047 0.0154
Loa Loa (eye worm) hypothetical protein 0.0026 0.0147 0.0672
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0105 0.0356
Echinococcus granulosus dnaJ subfamily B 0.0399 0.2874 1
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0375 0.2698 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0105 0.0356
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0122 1
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.0218
Echinococcus granulosus carboxylesterase 5A 0.0069 0.046 0.1591
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0105 0.0379
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0384 0.1328
Echinococcus multilocularis lamin 0.0026 0.0147 0.0503
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0083 0.0559 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0079 0.0355
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0066 0.0233
Loa Loa (eye worm) hypothetical protein 0.0017 0.0079 0.0355
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0004 0.0005
Trichomonas vaginalis importin beta-1, putative 0.0023 0.012 1
Schistosoma mansoni hypothetical protein 0.0205 0.1453 0.505
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.2151 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0017 0.0049
Echinococcus multilocularis GPCR, family 2 0.0015 0.0065 0.0218
Mycobacterium ulcerans hypothetical protein 0.0023 0.0122 0.3115
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0066 0.0233
Onchocerca volvulus 0.0012 0.0039 0.0036
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0057 0.0254
Loa Loa (eye worm) hypothetical protein 0.0017 0.0079 0.0355
Brugia malayi Telomerase reverse transcriptase 0.0997 0.7256 1
Brugia malayi intermediate filament protein 0.0026 0.0147 0.0199
Plasmodium falciparum importin beta, putative 0.0028 0.0159 0.0581
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.0168
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.0168
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.2874 1
Onchocerca volvulus 0.0012 0.0039 0.0036
Brugia malayi hypothetical protein 0.0146 0.1025 0.141
Loa Loa (eye worm) hypothetical protein 0.0048 0.0307 0.1416
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0122 0.2136
Schistosoma mansoni lamin 0.0026 0.0147 0.0503
Echinococcus granulosus intermediate filament protein 0.0026 0.0147 0.0503
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0039 0.0126
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.0218
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0083 0.0559 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0065 0.0218
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0066 0.0233
Brugia malayi Carboxylesterase family protein 0.0012 0.0039 0.005
Echinococcus granulosus acetylcholinesterase 0.0069 0.046 0.1591
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0384 0.1328
Echinococcus granulosus lamin dm0 0.0026 0.0147 0.0503
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0122 0.3115
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0065 0.0218
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0195 0.0265
Echinococcus granulosus GPCR family 2 0.0015 0.0065 0.0218
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0072 0.182
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0047 0.0154
Loa Loa (eye worm) hypothetical protein 0.0017 0.0079 0.0355
Echinococcus multilocularis musashi 0.0026 0.0147 0.0503
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0079 0.2
Echinococcus granulosus geminin 0.0205 0.1453 0.505
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0122 0.3115

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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