Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0064 | 0.0628 | 0.0763 |
Mycobacterium ulcerans | hypothetical protein | 0.0105 | 0.1157 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0105 | 0.1157 | 0.141 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0114 | 0.2706 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.0407 | 0.0473 |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.0581 | 0.7336 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0105 | 0.1157 | 0.1354 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0064 | 0.0628 | 0.085 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0043 | 0.0329 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0105 | 0.1157 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Schistosoma mansoni | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0763 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0043 | 0.0046 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0297 | 0.0357 |
Brugia malayi | beta-lactamase | 0.0105 | 0.1157 | 0.1416 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0043 | 0.0329 |
Entamoeba histolytica | hypothetical protein | 0.0064 | 0.0628 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0064 | 0.0628 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0043 | 0.0046 |
Mycobacterium tuberculosis | Probable reductase | 0.0108 | 0.1196 | 0.1399 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0108 | 0.1196 | 0.1399 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0043 | 0.0038 |
Schistosoma mansoni | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0763 |
Mycobacterium tuberculosis | Conserved protein | 0.0105 | 0.1157 | 0.1354 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.0407 | 0.3491 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Mycobacterium tuberculosis | Conserved protein | 0.0105 | 0.1157 | 0.1354 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.4885 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0005 | 0.5 |
Schistosoma mansoni | axis inhibition protein axin | 0.0064 | 0.0628 | 0.0763 |
Schistosoma mansoni | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0763 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0105 | 0.1157 | 1 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0064 | 0.0628 | 0.0623 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0105 | 0.1157 | 0.1416 |
Schistosoma mansoni | axis inhibition protein axin | 0.0064 | 0.0628 | 0.0763 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0645 | 0.8172 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0043 | 0.0329 |
Mycobacterium ulcerans | beta-lactamase | 0.0105 | 0.1157 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0581 | 0.7336 | 0.8972 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.1059 | 0.129 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0064 | 0.0628 | 0.0763 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0064 | 0.0628 | 0.0763 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0064 | 0.0628 | 0.0623 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0224 | 0.2697 | 0.3265 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0043 | 0.0045 |
Brugia malayi | PXA domain containing protein | 0.0064 | 0.0628 | 0.0769 |
Mycobacterium ulcerans | lipase LipD | 0.0105 | 0.1157 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0672 | 0.8511 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.0407 | 0.3491 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.0407 | 0.3491 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0043 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0108 | 0.1196 | 0.1399 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0568 | 0.0767 |
Entamoeba histolytica | hypothetical protein | 0.0064 | 0.0628 | 1 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0064 | 0.0628 | 0.085 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0064 | 0.0628 | 0.0623 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0105 | 0.1157 | 0.1152 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.4885 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0114 | 0.0945 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0105 | 0.1157 | 0.1354 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0064 | 0.0628 | 0.0769 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0043 | 0.0329 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0114 | 0.014 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0043 | 0.0053 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0043 | 0.0045 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0297 | 0.4343 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0066 | 0.0648 | 0.0877 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0407 | 1 |
Loa Loa (eye worm) | RGS-3 protein | 0.0064 | 0.0628 | 0.072 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0105 | 0.1157 | 0.137 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0064 | 0.0628 | 0.0623 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0581 | 0.7336 | 0.8977 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0108 | 0.1196 | 0.1399 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0114 | 0.0945 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0105 | 0.1157 | 0.1354 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0043 | 0.0038 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0568 | 0.0661 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0105 | 0.1157 | 1 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0064 | 0.0628 | 0.0763 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0297 | 0.0364 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0108 | 0.1196 | 0.1399 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0105 | 0.1157 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.0689 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0043 | 0.0329 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0043 | 0.0046 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0105 | 0.1157 | 0.1354 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0407 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0105 | 0.1157 | 0.1571 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0098 | 0.1059 | 0.1249 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.1059 | 0.129 |
Onchocerca volvulus | 0.0105 | 0.1157 | 0.5 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.1059 | 0.1054 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0568 | 0.4885 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0105 | 0.1157 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.0407 | 0.0448 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0108 | 0.1196 | 0.1982 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0043 | 0.0329 |
Schistosoma mansoni | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0763 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0114 | 0.0087 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0066 | 0.0648 | 0.0643 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0114 | 0.0945 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.0407 | 0.3491 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0297 | 0.0398 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0066 | 0.0648 | 0.0744 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.0407 | 0.0499 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0105 | 0.1157 | 1 |
Brugia malayi | glutathione reductase | 0.0047 | 0.0407 | 0.0499 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0043 | 0.0329 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0064 | 0.0628 | 0.0623 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0064 | 0.0628 | 0.0769 |
Schistosoma mansoni | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0763 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0064 | 0.0628 | 0.072 |
Brugia malayi | PXA domain containing protein | 0.0064 | 0.0628 | 0.0769 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.012 | 0.1352 | 0.1583 |
Echinococcus multilocularis | expressed protein | 0.0064 | 0.0628 | 0.0623 |
Onchocerca volvulus | 0.0105 | 0.1157 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0623 |
Leishmania major | trypanothione reductase | 0.0047 | 0.0407 | 0.3491 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0114 | 0.2706 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0108 | 0.1196 | 0.1399 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0114 | 0.0945 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Onchocerca volvulus | 0.0105 | 0.1157 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0064 | 0.0628 | 0.0623 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0043 | 0.0052 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0568 | 0.0563 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0064 | 0.0628 | 0.085 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0114 | 0.0945 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0297 | 0.0357 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0005 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.012 | 0.1352 | 0.1583 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0297 | 0.4343 |
Echinococcus granulosus | axis inhibition protein axin | 0.0064 | 0.0628 | 0.085 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0105 | 0.1157 | 0.1354 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0064 | 0.0628 | 0.085 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.0581 | 0.7336 | 0.7335 |
Echinococcus granulosus | axis inhibition protein axin | 0.0064 | 0.0628 | 0.085 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0064 | 0.0628 | 0.0769 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0005 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0043 | 0.0053 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0064 | 0.0628 | 0.072 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0098 | 0.1059 | 0.1295 |
Loa Loa (eye worm) | beta-lactamase | 0.0105 | 0.1157 | 0.137 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.1059 | 0.1054 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0043 | 0.0052 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0064 | 0.0628 | 0.0623 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0043 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0628 | 0.0769 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0105 | 0.1157 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0645 | 0.8172 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0648 | 0.0787 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0064 | 0.0628 | 0.0769 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0105 | 0.1157 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0105 | 0.1157 | 0.1416 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.012 | 0.1352 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.1059 | 0.129 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.1059 | 0.1437 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.1059 | 0.1437 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0105 | 0.1157 | 0.141 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0105 | 0.1157 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0297 | 0.4343 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0297 | 0.4343 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.0407 | 0.0448 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0064 | 0.0628 | 0.0769 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.0407 | 0.0402 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0064 | 0.0628 | 0.5408 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0043 | 1 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0105 | 0.1157 | 0.1354 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0043 | 0.0052 |
Leishmania major | hypothetical protein, conserved | 0.0105 | 0.1157 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Brugia malayi | follicle stimulating hormone receptor | 0.0224 | 0.2697 | 0.33 |
Toxoplasma gondii | ABC1 family protein | 0.0105 | 0.1157 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0105 | 0.1157 | 0.1354 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.4885 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0105 | 0.1157 | 1 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0064 | 0.0628 | 0.085 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.0689 |
Echinococcus granulosus | expressed protein | 0.0064 | 0.0628 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0297 | 0.0292 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0628 | 0.0769 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0645 | 0.8172 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0105 | 0.1157 | 0.1416 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.4885 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0105 | 0.1157 | 0.1354 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.012 | 0.1352 | 0.1583 |
Trichomonas vaginalis | esterase, putative | 0.0105 | 0.1157 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0005 | 0.0007 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0043 | 0.0329 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.0581 | 0.7336 | 0.8972 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0648 | 0.0787 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0114 | 0.0945 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0064 | 0.0628 | 0.0623 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0064 | 0.0628 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0016 | 0.0005 | 0.5 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.0407 | 0.3491 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.0407 | 0.0548 |
Plasmodium vivax | hypothetical protein, conserved | 0.0105 | 0.1157 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.