Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0114 | 0.0945 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0064 | 0.0628 | 0.085 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.012 | 0.1352 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0297 | 0.0292 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0043 | 0.0046 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0043 | 0.0329 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0648 | 0.0787 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0108 | 0.1196 | 0.1399 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0114 | 0.0945 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0297 | 0.0364 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0407 | 1 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0064 | 0.0628 | 0.0623 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.0407 | 0.3491 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0064 | 0.0628 | 0.0623 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.012 | 0.1352 | 0.1583 |
Echinococcus multilocularis | expressed protein | 0.0064 | 0.0628 | 0.0623 |
Entamoeba histolytica | hypothetical protein | 0.0064 | 0.0628 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0098 | 0.1059 | 0.1295 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0005 | 0.0007 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0064 | 0.0628 | 0.0763 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0066 | 0.0648 | 0.0643 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0623 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0114 | 0.0945 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.1059 | 0.1054 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0114 | 0.0945 |
Brugia malayi | PXA domain containing protein | 0.0064 | 0.0628 | 0.0769 |
Leishmania major | hypothetical protein, conserved | 0.0105 | 0.1157 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0105 | 0.1157 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.0407 | 0.3491 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0108 | 0.1196 | 0.1982 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0043 | 0.0038 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0407 | 1 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0064 | 0.0628 | 0.0769 |
Schistosoma mansoni | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0763 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0105 | 0.1157 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0224 | 0.2697 | 0.33 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0064 | 0.0628 | 0.085 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.0407 | 0.0448 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Schistosoma mansoni | axis inhibition protein axin | 0.0064 | 0.0628 | 0.0763 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0105 | 0.1157 | 0.1354 |
Mycobacterium ulcerans | lipase LipD | 0.0105 | 0.1157 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0297 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0105 | 0.1157 | 0.1354 |
Echinococcus granulosus | axis inhibition protein axin | 0.0064 | 0.0628 | 0.085 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0064 | 0.0628 | 0.085 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0043 | 0.0329 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0105 | 0.1157 | 0.1354 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0064 | 0.0628 | 0.072 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0043 | 0.0329 |
Trichomonas vaginalis | esterase, putative | 0.0105 | 0.1157 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0105 | 0.1157 | 0.1416 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.0689 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0581 | 0.7336 | 0.8977 |
Schistosoma mansoni | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0763 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.0689 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0064 | 0.0628 | 0.0623 |
Mycobacterium tuberculosis | Conserved protein | 0.0105 | 0.1157 | 0.1354 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0297 | 0.4343 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0005 | 0.5 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.0581 | 0.7336 | 0.7335 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0064 | 0.0628 | 0.0623 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0016 | 0.0005 | 0.5 |
Mycobacterium tuberculosis | Probable reductase | 0.0108 | 0.1196 | 0.1399 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0105 | 0.1157 | 0.1416 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0105 | 0.1157 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0568 | 0.4885 |
Mycobacterium tuberculosis | Conserved protein | 0.0105 | 0.1157 | 0.1354 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.0407 | 0.0473 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0297 | 0.4343 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0043 | 0.0329 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0064 | 0.0628 | 0.072 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0224 | 0.2697 | 0.3265 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0114 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.0581 | 0.7336 | 1 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0064 | 0.0628 | 0.0623 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0645 | 0.8172 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.0407 | 0.3491 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.1059 | 0.1054 |
Mycobacterium ulcerans | beta-lactamase | 0.0105 | 0.1157 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0648 | 0.0787 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0043 | 0.0053 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.0407 | 0.3491 |
Entamoeba histolytica | hypothetical protein | 0.0064 | 0.0628 | 1 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0105 | 0.1157 | 0.1354 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0043 | 0.0329 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.1059 | 0.129 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.4885 |
Schistosoma mansoni | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0763 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0043 | 0.0045 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0105 | 0.1157 | 0.1354 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0005 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0108 | 0.1196 | 0.1399 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0105 | 0.1157 | 0.137 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.1059 | 0.129 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0581 | 0.7336 | 0.8972 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0043 | 0.0053 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0105 | 0.1157 | 0.141 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0568 | 0.0563 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0064 | 0.0628 | 0.5408 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0066 | 0.0648 | 0.0877 |
Toxoplasma gondii | ABC1 family protein | 0.0105 | 0.1157 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0043 | 0.0329 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0064 | 0.0628 | 0.0769 |
Brugia malayi | PXA domain containing protein | 0.0064 | 0.0628 | 0.0769 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0043 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0114 | 0.2706 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0105 | 0.1157 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0043 | 0.0052 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0105 | 0.1157 | 0.1354 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0064 | 0.0628 | 0.0769 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0105 | 0.1157 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0105 | 0.1157 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0105 | 0.1157 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0043 | 0.0052 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0105 | 0.1157 | 0.1152 |
Echinococcus granulosus | expressed protein | 0.0064 | 0.0628 | 0.085 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0043 | 0.0038 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0064 | 0.0628 | 0.0763 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.1059 | 0.1437 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0105 | 0.1157 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0043 | 0.0329 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0098 | 0.1059 | 0.1249 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Mycobacterium tuberculosis | Conserved protein | 0.0105 | 0.1157 | 0.1354 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Leishmania major | trypanothione reductase | 0.0047 | 0.0407 | 0.3491 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.0407 | 0.3491 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0043 | 0.0046 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Brugia malayi | glutathione reductase | 0.0047 | 0.0407 | 0.0499 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0297 | 0.4343 |
Loa Loa (eye worm) | RGS-3 protein | 0.0064 | 0.0628 | 0.072 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0108 | 0.1196 | 0.1399 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0064 | 0.0628 | 0.0623 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0043 | 0.0329 |
Onchocerca volvulus | 0.0105 | 0.1157 | 0.5 | |
Schistosoma mansoni | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0763 |
Onchocerca volvulus | 0.0105 | 0.1157 | 0.5 | |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0043 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0297 | 0.0357 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0628 | 0.0769 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0064 | 0.0628 | 0.0623 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0114 | 0.014 |
Brugia malayi | beta-lactamase family protein | 0.0105 | 0.1157 | 0.1416 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0064 | 0.0628 | 0.085 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.012 | 0.1352 | 0.1583 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.1059 | 0.1437 |
Brugia malayi | beta-lactamase | 0.0105 | 0.1157 | 0.1416 |
Plasmodium vivax | hypothetical protein, conserved | 0.0105 | 0.1157 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.1059 | 0.129 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0568 | 0.0661 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0064 | 0.0628 | 0.085 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0672 | 0.8511 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0043 | 0.0045 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0005 | 0.5 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0043 | 0.0052 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0645 | 0.8172 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0105 | 0.1157 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.012 | 0.1352 | 0.1583 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0114 | 0.0945 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0043 | 0.0329 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0297 | 0.0357 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0064 | 0.0628 | 0.0769 |
Schistosoma mansoni | axis inhibition protein axin | 0.0064 | 0.0628 | 0.0763 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0114 | 0.0945 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0105 | 0.1157 | 0.1571 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0105 | 0.1157 | 0.1354 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.4885 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0628 | 0.072 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1157 | 0.137 |
Schistosoma mansoni | regulator of G protein signaling | 0.0064 | 0.0628 | 0.0763 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0568 | 0.0767 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.0407 | 0.0499 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0108 | 0.1196 | 0.1399 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0628 | 0.5408 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0064 | 0.0628 | 0.0763 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0645 | 0.8172 | 1 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.0581 | 0.7336 | 0.8972 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0064 | 0.0628 | 0.0763 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0043 | 0.0046 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.0407 | 0.0448 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.4885 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0064 | 0.0628 | 0.085 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0568 | 0.4885 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0108 | 0.1196 | 0.1399 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0064 | 0.0628 | 0.0769 |
Onchocerca volvulus | 0.0105 | 0.1157 | 0.5 | |
Echinococcus granulosus | axis inhibition protein axin | 0.0064 | 0.0628 | 0.085 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0628 | 0.0769 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0105 | 0.1157 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0114 | 0.2706 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0297 | 0.4343 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.0407 | 0.0402 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0105 | 0.1157 | 0.141 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.0407 | 0.0548 |
Loa Loa (eye worm) | beta-lactamase | 0.0105 | 0.1157 | 0.137 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0043 | 0.0329 |
Entamoeba histolytica | hypothetical protein | 0.0064 | 0.0628 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0105 | 0.1157 | 1 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0066 | 0.0648 | 0.0744 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0043 | 0.0329 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0064 | 0.0628 | 0.0623 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.