Detailed information for compound 675541

Basic information

Technical information
  • TDR Targets ID: 675541
  • Name: 2-(4-bromo-2-methylphenoxy)-N-(5,6,7,8-tetrah ydronaphthalen-1-yl)acetamide
  • MW: 374.272 | Formula: C19H20BrNO2
  • H donors: 1 H acceptors: 1 LogP: 5.23 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cccc2c1CCCC2)COc1ccc(cc1C)Br
  • InChi: 1S/C19H20BrNO2/c1-13-11-15(20)9-10-18(13)23-12-19(22)21-17-8-4-6-14-5-2-3-7-16(14)17/h4,6,8-11H,2-3,5,7,12H2,1H3,(H,21,22)
  • InChiKey: OFYBOXIIKLJGNJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(4-bromo-2-methyl-phenoxy)-N-tetralin-5-yl-acetamide
  • 2-(4-bromo-2-methylphenoxy)-N-(5-tetralinyl)acetamide
  • 2-(4-bromo-2-methyl-phenoxy)-N-(5,6,7,8-tetrahydronaphthalen-1-yl)ethanamide
  • ZINC01159658
  • STK122834

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii protein kinase, putative 0.0603 0.6603 1
Plasmodium falciparum calcium-dependent protein kinase 2 0.0065 0.0574 0.0404
Echinococcus granulosus General substrate transporter 0.0183 0.1897 0.5128
Echinococcus granulosus lysyl tRNA synthetase 0.0048 0.0374 0.098
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0177 0.0299
Echinococcus multilocularis solute carrier family 22 0.003 0.0177 0.0441
Schistosoma mansoni hypothetical protein 0.0035 0.0238 0.0609
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0583 0.8107
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0374 0.098
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.2234 0.7653
Onchocerca volvulus 0.003 0.0177 0.0361
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Echinococcus granulosus calcium dependent protein kinase 0.0061 0.0528 0.1398
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0294 1
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0064 0.0558 1
Brugia malayi hypothetical protein 0.003 0.0177 0.0479
Echinococcus granulosus sodium:glucose cotransporter 0.0038 0.0264 0.068
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0294 1
Plasmodium falciparum hexose transporter 0.0213 0.2234 0.2094
Brugia malayi hypothetical protein 0.003 0.0177 0.0479
Echinococcus granulosus high affinity choline transporter 1 0.0343 0.3686 1
Leishmania major glucose transporter/membrane transporter D2, putative 0.0066 0.0583 0.8107
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0213 0.2234 0.6044
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0345 0.3708 0.5495
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0065 0.0573 0.1555
Schistosoma mansoni sugar transporter 0.003 0.0177 0.0441
Trypanosoma brucei glucose transporter, putative 0.0066 0.0583 0.8107
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.02 0.2089 0.5666
Echinococcus multilocularis General substrate transporter 0.0183 0.1897 0.5128
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0392 0.1063
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0064 0.0558 0.1481
Echinococcus multilocularis calcium dependent protein kinase 0.0061 0.0528 0.1398
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0065 0.0573 0.1555
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0015 0.004
Loa Loa (eye worm) sugar transporter 0.0213 0.2234 0.606
Brugia malayi Sodium:solute symporter family protein 0.0038 0.0264 0.0717
Onchocerca volvulus 0.003 0.0177 0.0361
Loa Loa (eye worm) hypothetical protein 0.0038 0.0264 0.0717
Plasmodium falciparum mitogen-activated protein kinase 2 0.0345 0.3708 0.3595
Onchocerca volvulus 0.003 0.0177 0.0361
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0167 0.1712 0.4621
Plasmodium falciparum calcium-dependent protein kinase 4 0.0065 0.0574 0.0404
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0677 1
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0048 0.0374 0.395
Echinococcus multilocularis lamin 0.0027 0.0139 0.0337
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0583 0.8107
Echinococcus granulosus sodium:myo inositol cotransporter 0.0038 0.0264 0.068
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0583 0.151
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0213 0.2234 0.6044
Loa Loa (eye worm) hypothetical protein 0.0048 0.0374 0.1016
Toxoplasma gondii lysine-tRNA ligase 0.0048 0.0374 0.0308
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0345 0.3708 0.3595
Schistosoma mansoni sugar transporter 0.003 0.0177 0.0441
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0038 0.0264 0.068
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0038 0.0264 0.068
Onchocerca volvulus 0.003 0.0177 0.0361
Echinococcus granulosus solute carrier family 22 0.003 0.0177 0.0441
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Schistosoma mansoni sugar transporter 0.003 0.0177 0.0441
Schistosoma mansoni hypothetical protein 0.0034 0.0217 0.0552
Brugia malayi glutaminase DH11.1 0.027 0.2865 0.7772
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0583 0.151
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0573 0.1521
Trypanosoma brucei glucose transporter, putative 0.0066 0.0583 0.8107
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0177 0.0299
Schistosoma mansoni sodium/solute symporter 0.0038 0.0264 0.068
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0583 0.151
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0213 0.2234 0.6044
Trypanosoma brucei glucose transporter, putative 0.0066 0.0583 0.8107
Onchocerca volvulus 0.003 0.0177 0.0361
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Schistosoma mansoni glucose transport protein 0.0213 0.2234 0.6044
Echinococcus multilocularis solute carrier family 22 0.003 0.0177 0.0441
Plasmodium vivax CDK-related protein kinase 6, putative 0.0906 1 1
Brugia malayi hypothetical protein 0.0035 0.0238 0.0646
Loa Loa (eye worm) sugar transporter 0.003 0.0177 0.0479
Loa Loa (eye worm) glutaminase 2 0.027 0.2865 0.7772
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Loa Loa (eye worm) hypothetical protein 0.0064 0.0558 0.1515
Brugia malayi Cam kinase protein 1 0.0065 0.0573 0.1555
Loa Loa (eye worm) hypothetical protein 0.0026 0.0133 0.0361
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Schistosoma mansoni glucose transporter 0.003 0.0177 0.0441
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0015 0.004
Onchocerca volvulus Putative transporter 0.003 0.0177 0.0361
Schistosoma mansoni high-affinity choline transporter 0.0343 0.3686 1
Leishmania major lysyl-tRNA synthetase, putative 0.0048 0.0374 0.395
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Plasmodium falciparum calcium-dependent protein kinase 3 0.0065 0.0574 0.0404
Onchocerca volvulus 0.003 0.0177 0.0361
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0583 0.151
Brugia malayi Sugar transporter family protein 0.003 0.0177 0.0479
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0048 0.0374 0.3046
Brugia malayi hypothetical protein 0.003 0.0177 0.0479
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0677 1
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0038 0.0264 0.0136
Plasmodium falciparum proline--tRNA ligase 0.0075 0.0677 0.051
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0246 0.1383
Echinococcus multilocularis solute carrier family 22 0.003 0.0177 0.0441
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Giardia lamblia Prolyl-tRNA synthetase 0.0064 0.0558 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0583 0.8107
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0065 0.0573 0.7919
Schistosoma mansoni protein kinase 0.0065 0.0573 0.1521
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0217 0.0589
Plasmodium falciparum calcium-dependent protein kinase 5 0.0065 0.0574 0.0404
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.0573 0.1475
Schistosoma mansoni protein kinase 0.0065 0.0573 0.1521
Entamoeba histolytica protein kinase, putative 0.0065 0.0573 1
Onchocerca volvulus 0.003 0.0177 0.0361
Schistosoma mansoni glucose transport protein 0.0213 0.2234 0.6044
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0048 0.0374 0.395
Onchocerca volvulus 0.003 0.0177 0.0361
Schistosoma mansoni hypothetical protein 0.0213 0.2234 0.6044
Entamoeba histolytica protein kinase, putative 0.0065 0.0573 1
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0177 0.0441
Brugia malayi Sugar transporter family protein 0.003 0.0177 0.0479
Schistosoma mansoni inositol transporter 0.0038 0.0264 0.068
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0065 0.0573 0.1521
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0177 0.0441
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0583 0.8107
Mycobacterium ulcerans glutaminase 0.027 0.2865 1
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0583 0.151
Leishmania major glucose transporter, lmgt1 0.0066 0.0583 0.8107
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0042 0.0309 0.0491
Onchocerca volvulus 0.003 0.0177 0.0361
Echinococcus granulosus solute carrier family 22 0.003 0.0177 0.0441
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Echinococcus multilocularis solute carrier family 5 0.0038 0.0264 0.068
Loa Loa (eye worm) hypothetical protein 0.0064 0.0558 0.1515
Loa Loa (eye worm) glutaminase 0.027 0.2865 0.7772
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0374 0.098
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0177 0.0479
Trypanosoma brucei glucose transporter, putative 0.0066 0.0583 0.8107
Schistosoma mansoni sugar transporter 0.003 0.0177 0.0441
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0392 0.1063
Leishmania major glucose transporter, lmgt2 0.0066 0.0583 0.8107
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0065 0.0574 0.0404
Echinococcus granulosus lamin dm0 0.0027 0.0139 0.0337
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0038 0.0264 0.068
Schistosoma mansoni intermediate filament proteins 0.0027 0.0139 0.0337
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0583 0.151
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0065 0.0574 0.0404
Trichomonas vaginalis glutaminase, putative 0.027 0.2865 1
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0177 0.0479
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0135 0.0366
Toxoplasma gondii facilitative glucose transporter GT1 0.0213 0.2234 0.3201
Plasmodium falciparum lysine--tRNA ligase 0.0048 0.0374 0.0201
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Echinococcus multilocularis lamin dm0 0.0027 0.0139 0.0337
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0213 0.2234 0.6044
Echinococcus multilocularis high affinity choline transporter 1 0.0343 0.3686 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0583 0.8107
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0167 0.1712 0.4621
Brugia malayi major facilitator superfamily protein 0.003 0.0177 0.0479
Loa Loa (eye worm) hypothetical protein 0.02 0.2089 0.5666
Brugia malayi intermediate filament protein 0.0027 0.0139 0.0376
Onchocerca volvulus 0.003 0.0177 0.0361
Onchocerca volvulus 0.003 0.0177 0.0361
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0677 1
Plasmodium falciparum protein kinase 7 0.0603 0.6603 0.6542
Brugia malayi GH02984p 0.0343 0.3686 1
Onchocerca volvulus Huntingtin homolog 0.0121 0.1196 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0583 0.8107
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0573 0.1521
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0573 0.1521
Plasmodium vivax calcium-dependent protein kinase, putative 0.0065 0.0574 0.0404
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0065 0.0574 0.0617
Trypanosoma cruzi hexose transporter 0.0066 0.0583 0.8107
Plasmodium falciparum calcium-dependent protein kinase 1 0.0065 0.0574 0.0404
Schistosoma mansoni glucose transport protein 0.0213 0.2234 0.6044
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0583 0.151
Plasmodium vivax hexose transporter 0.0213 0.2234 0.2094
Onchocerca volvulus 0.003 0.0177 0.0361
Plasmodium vivax lysine--tRNA ligase, putative 0.0048 0.0374 0.0201
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0177 0.0479
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0177 0.0441
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0213 0.2234 0.6044
Trypanosoma brucei glucose transporter 1E 0.0066 0.0583 0.8107
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0573 0.1521
Loa Loa (eye worm) hypothetical protein 0.0065 0.0573 0.1555
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0213 0.2234 0.6044
Brugia malayi Sugar transporter family protein 0.0213 0.2234 0.606
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0558 0.1481
Onchocerca volvulus 0.0038 0.0264 0.119
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0677 1
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0065 0.0574 0.0404
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0064 0.0558 0.1419
Echinococcus multilocularis solute carrier family 22 0.003 0.0177 0.0441
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0177 0.0441
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0238 0.0609
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Onchocerca volvulus Huntingtin homolog 0.0121 0.1196 1
Loa Loa (eye worm) hypothetical protein 0.0343 0.3686 1
Leishmania major protein kinase, putative 0.0065 0.0573 0.7919
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0139 0.0376
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Trypanosoma brucei glucose transporter, putative 0.0066 0.0583 0.8107
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0238 0.0609
Onchocerca volvulus 0.003 0.0177 0.0361
Loa Loa (eye worm) hypothetical protein 0.0052 0.0424 0.1149
Echinococcus granulosus lamin 0.0027 0.0139 0.0337
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0238 0.0609
Schistosoma mansoni lamin 0.0027 0.0139 0.0337
Schistosoma mansoni lamin 0.0027 0.0139 0.0337
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0075 0.0677 0.0779
Brugia malayi major facilitator superfamily protein 0.003 0.0177 0.0479
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0139 0.0376
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0038 0.0264 0.068
Schistosoma mansoni inositol transporter 0.0038 0.0264 0.068
Trypanosoma brucei glucose transporter 2A 0.0066 0.0583 0.8107
Echinococcus granulosus solute carrier family 22 0.003 0.0177 0.0441
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0048 0.0374 0.0736
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0374 0.1013
Loa Loa (eye worm) hypothetical protein 0.0121 0.1196 0.3244
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0213 0.2234 0.6044
Plasmodium vivax proline--tRNA ligase, putative 0.0075 0.0677 0.051
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0177 0.0441
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0677 1
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0573 0.1521
Loa Loa (eye worm) hypothetical protein 0.0027 0.0139 0.0376
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0177 0.0479
Onchocerca volvulus 0.003 0.0177 0.0361
Loa Loa (eye worm) hypothetical protein 0.0121 0.1196 0.3244
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0064 0.0558 0.1515
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0177 0.0299
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0558 0.1481
Trypanosoma brucei glucose transporter, putative 0.0066 0.0583 0.8107
Trypanosoma brucei glucose transporter, putative 0.0066 0.0583 0.8107
Onchocerca volvulus 0.003 0.0177 0.0361
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0064 0.0558 0.1481
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.004
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0064 0.0558 0.9557
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0094 0.5
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0213 0.2234 0.6044
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0177 0.0479
Trypanosoma brucei glucose transporter, putative 0.0066 0.0583 0.8107
Echinococcus multilocularis musashi 0.0027 0.0139 0.0337
Echinococcus multilocularis lysyl tRNA synthetase 0.0048 0.0374 0.098
Echinococcus granulosus intermediate filament protein 0.0027 0.0139 0.0337
Brugia malayi hypothetical protein 0.0121 0.1196 0.3244
Echinococcus granulosus sodium:glucose cotransporter 2 0.0038 0.0264 0.068
Mycobacterium ulcerans sugar transporter 0.003 0.0177 0.0299
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0177 0.5
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0065 0.0574 0.0617
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0015 0.004
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0065 0.0574 0.0617
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Onchocerca volvulus 0.003 0.0177 0.0361
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0374 0.1013
Chlamydia trachomatis lysine--tRNA ligase 0.0048 0.0374 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Echinococcus granulosus solute carrier family 5 0.0038 0.0264 0.068
Echinococcus granulosus solute carrier family 22 0.003 0.0177 0.0441
Leishmania major glucose transporter, lmgt3 0.0066 0.0583 0.8107
Schistosoma mansoni glutaminase 0.027 0.2865 0.7763
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0573 0.1521
Brugia malayi lysyl-tRNA synthetase 0.0048 0.0374 0.1016
Schistosoma mansoni protein kinase 0.0065 0.0573 0.1521
Loa Loa (eye worm) hypothetical protein 0.0034 0.0217 0.0589
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0573 0.1521
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0573 0.1521
Entamoeba histolytica hypothetical protein 0.0048 0.0374 0.4067
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0064 0.0558 0.1515
Giardia lamblia Lysyl-tRNA synthetase 0.0048 0.0374 0.5182
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0139 0.0376
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0479
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0065 0.0573 0.1555

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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