Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | phosphofructokinase, putative | 0.0116 | 0.0491 | 0.2207 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0058 | 0.0181 | 0.0722 |
Plasmodium vivax | phenylalanine--tRNA ligase, putative | 0.0186 | 0.0865 | 0.403 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0051 | 0.0143 | 0.0572 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0058 | 0.0181 | 0.0722 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0132 | 0.0527 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0494 | 0.2508 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0132 | 0.0527 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0116 | 0.0491 | 0.1959 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0116 | 0.0491 | 0.2352 |
Brugia malayi | 6-phosphofructokinase | 0.0116 | 0.0491 | 0.2302 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0132 | 0.0527 |
Plasmodium falciparum | phenylalanine--tRNA ligase alpha subunit | 0.0415 | 0.2088 | 1 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0051 | 0.0143 | 0.0572 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0116 | 0.0491 | 0.2007 |
Echinococcus multilocularis | phenylalanyl tRNA synthetase | 0.0186 | 0.0865 | 0.3449 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0143 | 0.0266 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0415 | 0.2088 | 1 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0201 | 0.0943 | 0.3761 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0051 | 0.0143 | 0.0687 |
Mycobacterium ulcerans | phenylalanyl-tRNA synthetase subunit alpha | 0.1899 | 1 | 1 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0116 | 0.0491 | 0.2207 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.0132 | 0.021 |
Toxoplasma gondii | Ferredoxin-fold anticodon binding domain-containing protein | 0.0186 | 0.0865 | 0.403 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0051 | 0.0143 | 0.0687 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0051 | 0.0143 | 0.0572 |
Brugia malayi | 6-phosphofructokinase | 0.0116 | 0.0491 | 0.2302 |
Brugia malayi | Bromodomain containing protein | 0.008 | 0.0299 | 0.1376 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0058 | 0.0181 | 0.0722 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0115 | 0.0122 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.009 | 0.0368 |
Schistosoma mansoni | hypothetical protein | 0.031 | 0.1524 | 0.7301 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase subunit alpha | 0.0415 | 0.2088 | 1 |
Treponema pallidum | phenylalanyl-tRNA synthetase subunit alpha | 0.0415 | 0.2088 | 1 |
Leishmania major | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0415 | 0.2088 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0212 | 0.0845 |
Loa Loa (eye worm) | hypothetical protein | 0.0415 | 0.2088 | 1 |
Mycobacterium tuberculosis | Probable phenylalanyl-tRNA synthetase, alpha chain PheS | 0.1899 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.0132 | 0.0572 |
Plasmodium falciparum | phenylalanine--tRNA ligase | 0.0186 | 0.0865 | 0.403 |
Trypanosoma cruzi | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0415 | 0.2088 | 1 |
Onchocerca volvulus | 0.0051 | 0.0143 | 0.5 | |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0051 | 0.0143 | 0.5 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0116 | 0.0491 | 0.2207 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0494 | 0.2508 | 1 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0051 | 0.0143 | 0.0572 |
Entamoeba histolytica | phenylalanyl-tRNA synthetase alpha subunit, putative | 0.0415 | 0.2088 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0116 | 0.0491 | 0.2352 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0051 | 0.0143 | 0.0687 |
Echinococcus granulosus | neuropeptide s receptor | 0.0494 | 0.2508 | 1 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0051 | 0.0143 | 0.0266 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0076 | 0.0304 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0494 | 0.2508 | 1 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase mitochondrial | 0.0186 | 0.0865 | 0.4141 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0132 | 0.0633 |
Echinococcus multilocularis | phenylalanyl tRNA synthetase alpha chain B | 0.0415 | 0.2088 | 0.8327 |
Trypanosoma brucei | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0415 | 0.2088 | 1 |
Loa Loa (eye worm) | phosphofructokinase | 0.0116 | 0.0491 | 0.2007 |
Brugia malayi | phosphofructokinase | 0.0116 | 0.0491 | 0.2302 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0116 | 0.0491 | 0.2207 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0132 | 0.0527 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0212 | 0.0845 |
Plasmodium falciparum | phenylalanine--tRNA ligase | 0.0154 | 0.0695 | 0.3203 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0132 | 0.0633 |
Brugia malayi | mbt repeat family protein | 0.0051 | 0.0143 | 0.0626 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0058 | 0.0181 | 0.0867 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase subunit alpha | 0.0136 | 0.0597 | 0.2858 |
Brugia malayi | phenylalanyl-tRNA synthetase, mitochondrial precursor, putative | 0.0186 | 0.0865 | 0.4103 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0116 | 0.0491 | 0.2207 |
Brugia malayi | mbt repeat family protein | 0.0051 | 0.0143 | 0.0626 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0136 | 0.0597 | 0.2723 |
Plasmodium vivax | phenylalanine--tRNA ligase alpha subunit, putative | 0.0415 | 0.2088 | 1 |
Loa Loa (eye worm) | MBCTL1 | 0.0058 | 0.0181 | 0.0455 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0116 | 0.0491 | 0.2207 |
Echinococcus granulosus | phenylalanyl tRNA synthetase alpha chain B | 0.0415 | 0.2088 | 0.8327 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0058 | 0.0181 | 0.0722 |
Toxoplasma gondii | phenylalanyl-tRNA synthetase alpha chain A, putative | 0.0415 | 0.2088 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0275 | 0.0923 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0058 | 0.0181 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0104 | 0.0068 |
Loa Loa (eye worm) | phenylalanyl-tRNA synthetase | 0.0186 | 0.0865 | 0.3877 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0116 | 0.0491 | 0.2207 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0076 | 0.0304 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0201 | 0.0943 | 0.3761 |
Giardia lamblia | Phenylalanyl-tRNA synthetase alpha chain | 0.0415 | 0.2088 | 1 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0116 | 0.0491 | 0.1959 |
Wolbachia endosymbiont of Brugia malayi | phenylalanyl-tRNA synthetase subunit alpha | 0.1899 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0181 | 0.0455 |
Brugia malayi | phenylalanyl (f) trna synthetase protein 1 | 0.0415 | 0.2088 | 1 |
Plasmodium vivax | phenylalanine--tRNA ligase, putative | 0.0136 | 0.0597 | 0.2723 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.0232 | 0.1112 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0136 | 0.0597 | 0.2723 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0116 | 0.0491 | 0.2207 |
Echinococcus granulosus | phenylalanyl tRNA synthetase | 0.0186 | 0.0865 | 0.3449 |
Mycobacterium leprae | Probable phenylalanyl-tRNA synthetase, alpha chain PheS | 0.028 | 0.1363 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0116 | 0.0491 | 0.2007 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0132 | 0.0633 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.