Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0264 | 0.5103 | 0.5003 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0078 | 0.0874 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0264 | 0.5103 | 0.6406 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0124 | 0.1939 | 0.2272 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Brugia malayi | FAD binding domain containing protein | 0.0078 | 0.0874 | 0.0687 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0124 | 0.1939 | 0.2272 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0124 | 0.1939 | 0.2272 |
Trichomonas vaginalis | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.1271 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0363 | 0.7361 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.045 | 0.9331 | 0.9317 |
Echinococcus multilocularis | nischarin | 0.0385 | 0.7853 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0259 | 0.4988 | 0.6256 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0264 | 0.5103 | 0.6531 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0053 | 0.031 | 0.0144 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0311 | 0.061 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.0311 | 0.0113 |
Entamoeba histolytica | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0264 | 0.5103 | 0.5003 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0264 | 0.5103 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0124 | 0.1939 | 0.2272 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0363 | 0.7361 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0124 | 0.1939 | 0.3799 |
Chlamydia trachomatis | sulfite reductase | 0.0048 | 0.02 | 0.5 |
Brugia malayi | tailless protein | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0264 | 0.5103 | 0.5003 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0264 | 0.5103 | 0.6531 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0078 | 0.0874 | 0.0799 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.012 | 0.1844 | 0.8342 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0078 | 0.0874 | 0.088 |
Echinococcus granulosus | nischarin | 0.0385 | 0.7853 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0139 | 0.2277 | 0.4463 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | nuclear hormone receptor | 0.0124 | 0.1939 | 0.1774 |
Schistosoma mansoni | thyroid hormone receptor | 0.0264 | 0.5103 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0139 | 0.2277 | 0.2714 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | vesicular acetylcholine transporter unc-17 | 0.0218 | 0.4065 | 0.3944 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0139 | 0.2277 | 0.4463 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Onchocerca volvulus | 0.0124 | 0.1939 | 0.2218 | |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0053 | 0.031 | 0.0144 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0124 | 0.1939 | 0.1774 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0264 | 0.5103 | 0.6406 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0134 | 0.2149 | 1 |
Onchocerca volvulus | 0.0264 | 0.5103 | 0.6531 | |
Trichomonas vaginalis | sulfite reductase, putative | 0.0078 | 0.0874 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0264 | 0.5103 | 0.5003 |
Mycobacterium tuberculosis | Probable reductase | 0.012 | 0.1844 | 0.8342 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.4988 | 0.5244 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0124 | 0.1939 | 0.3799 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0264 | 0.5103 | 0.6406 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0264 | 0.5103 | 0.6406 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0139 | 0.2277 | 0.212 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0124 | 0.1939 | 0.2218 |
Schistosoma mansoni | nuclear receptor | 0.0124 | 0.1939 | 0.3799 |
Echinococcus granulosus | FTZ F1 alpha | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.7361 | 0.7843 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0124 | 0.1939 | 0.1774 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.3329 | 0.3426 |
Echinococcus multilocularis | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0652 |
Brugia malayi | ecdysone receptor | 0.0124 | 0.1939 | 0.1774 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0124 | 0.1939 | 0.1904 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0264 | 0.5103 | 0.6406 |
Schistosoma mansoni | coup transcription factor | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Echinococcus granulosus | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0652 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0546 |
Schistosoma mansoni | zinc finger protein | 0.0124 | 0.1939 | 0.3799 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | hypothetical protein | 0.0124 | 0.1939 | 0.1774 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0134 | 0.2149 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0139 | 0.2277 | 0.2275 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | hypothetical protein | 0.0124 | 0.1939 | 0.1774 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.0218 | 0.4065 | 0.5117 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0264 | 0.5103 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0134 | 0.2149 | 1 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0078 | 0.0874 | 0.088 |
Onchocerca volvulus | 0.0124 | 0.1939 | 0.2218 | |
Leishmania major | p450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0124 | 0.1939 | 0.1904 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0069 | 0.0673 | 0.6446 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.0218 | 0.4065 | 0.4233 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0078 | 0.0874 | 0.1712 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0134 | 0.2149 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0264 | 0.5103 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Brugia malayi | hypothetical protein | 0.0139 | 0.2277 | 0.212 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0264 | 0.5103 | 0.537 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0078 | 0.0874 | 0.088 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0078 | 0.0874 | 0.0799 |
Trypanosoma cruzi | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.0551 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0264 | 0.5103 | 0.5003 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.0218 | 0.4065 | 0.7966 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0264 | 0.5103 | 0.5003 |
Toxoplasma gondii | deoxyhypusine synthase | 0.007 | 0.0699 | 1 |
Schistosoma mansoni | deoxyhypusine synthase | 0.007 | 0.0699 | 0.137 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0124 | 0.1939 | 0.3799 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0078 | 0.0874 | 0.088 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0139 | 0.2277 | 0.212 |
Brugia malayi | steroid hormone receptor | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0264 | 0.5103 | 0.537 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0124 | 0.1939 | 0.2272 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0124 | 0.1939 | 0.2272 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | ecdysteroid receptor | 0.0264 | 0.5103 | 0.5003 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Leishmania major | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.0551 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Entamoeba histolytica | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0264 | 0.5103 | 1 |
Brugia malayi | glutathione reductase | 0.0053 | 0.031 | 0.0112 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.0311 | 0.061 |
Plasmodium vivax | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.6898 |
Brugia malayi | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0509 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0078 | 0.0874 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.012 | 0.1844 | 0.8342 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.012 | 0.1844 | 0.8342 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0264 | 0.5103 | 1 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0048 | 0.02 | 0.0392 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0053 | 0.031 | 0.0121 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.0218 | 0.4065 | 0.505 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0264 | 0.5103 | 0.537 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0124 | 0.1939 | 0.3799 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0078 | 0.0874 | 0.0799 |
Brugia malayi | nuclear receptor NHR-88 | 0.0124 | 0.1939 | 0.1774 |
Leishmania major | cytochrome P450 reductase, putative | 0.0069 | 0.0673 | 0.0515 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.012 | 0.1844 | 0.8342 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0259 | 0.4988 | 0.6256 |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.7652 | 0.8161 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0264 | 0.5103 | 0.5003 |
Giardia lamblia | Deoxyhypusine synthase, putative | 0.007 | 0.0699 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.9331 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0124 | 0.1939 | 0.2218 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0124 | 0.1939 | 0.2272 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0078 | 0.0874 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0264 | 0.5103 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Plasmodium falciparum | deoxyhypusine synthase | 0.007 | 0.0699 | 0.6898 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0264 | 0.5103 | 1 |
Brugia malayi | hypothetical protein | 0.0259 | 0.4988 | 0.4886 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0363 | 0.7361 | 1 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0078 | 0.0874 | 0.0738 |
Brugia malayi | nuclear receptor NHR-67 | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0124 | 0.1939 | 0.1774 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0264 | 0.5103 | 0.6406 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0264 | 0.5103 | 0.6531 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Brugia malayi | nuclear receptor RXR | 0.0124 | 0.1939 | 0.1774 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0124 | 0.1939 | 0.2272 |
Brugia malayi | conserved hypotetical protein | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0264 | 0.5103 | 0.5003 |
Trypanosoma brucei | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0551 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0363 | 0.7361 | 0.7307 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0874 | 0.0738 |
Brugia malayi | hypothetical protein | 0.0376 | 0.7652 | 0.7604 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0139 | 0.2277 | 0.2714 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0264 | 0.5103 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0053 | 0.031 | 0.0112 |
Brugia malayi | nuclear hormone receptor | 0.0264 | 0.5103 | 0.5003 |
Trypanosoma cruzi | p450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0264 | 0.5103 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0053 | 0.031 | 0.0121 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | DR-78 | 0.0124 | 0.1939 | 0.1904 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.0218 | 0.4065 | 0.505 |
Brugia malayi | flavodoxin family protein | 0.0078 | 0.0874 | 0.0687 |
Schistosoma mansoni | nuclear hormone receptor | 0.0124 | 0.1939 | 0.3799 |
Schistosoma mansoni | nuclear hormone receptor | 0.0264 | 0.5103 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | nuclear receptor RXR | 0.0139 | 0.2277 | 0.212 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0264 | 0.5103 | 0.6406 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0264 | 0.5103 | 0.5003 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.012 | 0.1844 | 0.8342 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0124 | 0.1939 | 0.1774 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0264 | 0.5103 | 0.6406 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Schistosoma mansoni | nuclear receptor | 0.0124 | 0.1939 | 0.3799 |
Brugia malayi | hypothetical protein | 0.0139 | 0.2277 | 0.212 |
Onchocerca volvulus | Nischarin homolog | 0.0376 | 0.7648 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 16.3 % | Ability to display a naloxone-reversible inhibition of electrically induced contractions in GPI in the presence of 1.0 microM bestatin at concentration 10 e-6 M | ChEMBL. | 2754695 |
Inhibition (functional) | = 47 % | Percentage inhibition of compound against morphine at 10 e-7 M in guinea pig ileum tissue | ChEMBL. | 2754695 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.