Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0124 | 0.1939 | 0.1774 |
Schistosoma mansoni | zinc finger protein | 0.0124 | 0.1939 | 0.3799 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0546 |
Echinococcus granulosus | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0652 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Schistosoma mansoni | coup transcription factor | 0.0264 | 0.5103 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0124 | 0.1939 | 0.1904 |
Brugia malayi | ecdysone receptor | 0.0124 | 0.1939 | 0.1774 |
Echinococcus multilocularis | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0652 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.3329 | 0.3426 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0124 | 0.1939 | 0.1774 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.7361 | 0.7843 |
Echinococcus granulosus | FTZ F1 alpha | 0.0264 | 0.5103 | 0.6406 |
Schistosoma mansoni | nuclear receptor | 0.0124 | 0.1939 | 0.3799 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0124 | 0.1939 | 0.2218 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0139 | 0.2277 | 0.212 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0264 | 0.5103 | 0.6406 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0264 | 0.5103 | 0.6406 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0124 | 0.1939 | 0.3799 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Mycobacterium tuberculosis | Probable reductase | 0.012 | 0.1844 | 0.8342 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.4988 | 0.5244 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0078 | 0.0874 | 1 |
Onchocerca volvulus | 0.0264 | 0.5103 | 0.6531 | |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0134 | 0.2149 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | hypothetical protein | 0.0139 | 0.2277 | 0.212 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0264 | 0.5103 | 1 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0078 | 0.0874 | 0.1712 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0134 | 0.2149 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.0218 | 0.4065 | 0.4233 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0069 | 0.0673 | 0.6446 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Leishmania major | p450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0134 | 0.2149 | 1 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0078 | 0.0874 | 0.088 |
Onchocerca volvulus | 0.0124 | 0.1939 | 0.2218 | |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0264 | 0.5103 | 1 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.0218 | 0.4065 | 0.5117 |
Brugia malayi | hypothetical protein | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0139 | 0.2277 | 0.2275 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0134 | 0.2149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0053 | 0.031 | 0.0144 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0311 | 0.061 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0264 | 0.5103 | 0.6531 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0259 | 0.4988 | 0.6256 |
Echinococcus multilocularis | nischarin | 0.0385 | 0.7853 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.045 | 0.9331 | 0.9317 |
Trichomonas vaginalis | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.1271 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0363 | 0.7361 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0124 | 0.1939 | 0.2272 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0124 | 0.1939 | 0.2272 |
Brugia malayi | FAD binding domain containing protein | 0.0078 | 0.0874 | 0.0687 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0264 | 0.5103 | 0.6406 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0124 | 0.1939 | 0.2272 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0264 | 0.5103 | 0.5003 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0078 | 0.0874 | 1 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0124 | 0.1939 | 0.1774 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0264 | 0.5103 | 0.6406 |
Onchocerca volvulus | 0.0124 | 0.1939 | 0.2218 | |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0053 | 0.031 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0139 | 0.2277 | 0.4463 |
Brugia malayi | vesicular acetylcholine transporter unc-17 | 0.0218 | 0.4065 | 0.3944 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0264 | 0.5103 | 0.5003 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0139 | 0.2277 | 0.2714 |
Schistosoma mansoni | thyroid hormone receptor | 0.0264 | 0.5103 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | nuclear hormone receptor | 0.0124 | 0.1939 | 0.1774 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0139 | 0.2277 | 0.4463 |
Echinococcus granulosus | nischarin | 0.0385 | 0.7853 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0264 | 0.5103 | 0.6531 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0078 | 0.0874 | 0.0799 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0078 | 0.0874 | 0.088 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.012 | 0.1844 | 0.8342 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | tailless protein | 0.0124 | 0.1939 | 0.1774 |
Chlamydia trachomatis | sulfite reductase | 0.0048 | 0.02 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0124 | 0.1939 | 0.3799 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0363 | 0.7361 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0124 | 0.1939 | 0.2272 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0264 | 0.5103 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Entamoeba histolytica | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.5 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.0311 | 0.0113 |
Brugia malayi | Thioredoxin reductase | 0.0053 | 0.031 | 0.0112 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0264 | 0.5103 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0139 | 0.2277 | 0.2714 |
Brugia malayi | hypothetical protein | 0.0376 | 0.7652 | 0.7604 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0874 | 0.0738 |
Trypanosoma brucei | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0551 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0363 | 0.7361 | 0.7307 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | conserved hypotetical protein | 0.0124 | 0.1939 | 0.1774 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0124 | 0.1939 | 0.2272 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Brugia malayi | nuclear receptor RXR | 0.0124 | 0.1939 | 0.1774 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0264 | 0.5103 | 0.6531 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0264 | 0.5103 | 0.6406 |
Brugia malayi | nuclear receptor NHR-67 | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0124 | 0.1939 | 0.1774 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0078 | 0.0874 | 0.0738 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0363 | 0.7361 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | hypothetical protein | 0.0259 | 0.4988 | 0.4886 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Plasmodium falciparum | deoxyhypusine synthase | 0.007 | 0.0699 | 0.6898 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0264 | 0.5103 | 0.6406 |
Schistosoma mansoni | thyroid hormone receptor | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Onchocerca volvulus | Nischarin homolog | 0.0376 | 0.7648 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0124 | 0.1939 | 0.3799 |
Brugia malayi | hypothetical protein | 0.0139 | 0.2277 | 0.212 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0264 | 0.5103 | 0.6406 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0124 | 0.1939 | 0.1774 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0264 | 0.5103 | 0.537 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.012 | 0.1844 | 0.8342 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0264 | 0.5103 | 0.5003 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0264 | 0.5103 | 0.6406 |
Brugia malayi | nuclear receptor RXR | 0.0139 | 0.2277 | 0.212 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0264 | 0.5103 | 0.5003 |
Schistosoma mansoni | nuclear hormone receptor | 0.0264 | 0.5103 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0124 | 0.1939 | 0.3799 |
Brugia malayi | flavodoxin family protein | 0.0078 | 0.0874 | 0.0687 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.0218 | 0.4065 | 0.505 |
Loa Loa (eye worm) | DR-78 | 0.0124 | 0.1939 | 0.1904 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0264 | 0.5103 | 0.6406 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0053 | 0.031 | 0.0121 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0264 | 0.5103 | 1 |
Trypanosoma cruzi | p450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Brugia malayi | nuclear hormone receptor | 0.0264 | 0.5103 | 0.5003 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.012 | 0.1844 | 0.8342 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0078 | 0.0874 | 0.5 |
Brugia malayi | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0509 |
Brugia malayi | glutathione reductase | 0.0053 | 0.031 | 0.0112 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.0311 | 0.061 |
Plasmodium vivax | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.6898 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Entamoeba histolytica | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.5 |
Leishmania major | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.0551 |
Brugia malayi | ecdysteroid receptor | 0.0264 | 0.5103 | 0.5003 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0124 | 0.1939 | 0.2272 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0124 | 0.1939 | 0.2272 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0139 | 0.2277 | 0.212 |
Brugia malayi | steroid hormone receptor | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0124 | 0.1939 | 0.3799 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0078 | 0.0874 | 0.088 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Schistosoma mansoni | deoxyhypusine synthase | 0.007 | 0.0699 | 0.137 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0264 | 0.5103 | 0.5003 |
Toxoplasma gondii | deoxyhypusine synthase | 0.007 | 0.0699 | 1 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.0218 | 0.4065 | 0.7966 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0264 | 0.5103 | 0.5003 |
Trypanosoma cruzi | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.0551 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0078 | 0.0874 | 0.0799 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0078 | 0.0874 | 0.088 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0264 | 0.5103 | 0.537 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0078 | 0.0874 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0124 | 0.1939 | 0.2272 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0124 | 0.1939 | 0.2218 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Giardia lamblia | Deoxyhypusine synthase, putative | 0.007 | 0.0699 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.9331 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.7652 | 0.8161 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0259 | 0.4988 | 0.6256 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.012 | 0.1844 | 0.8342 |
Leishmania major | cytochrome P450 reductase, putative | 0.0069 | 0.0673 | 0.0515 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0078 | 0.0874 | 0.0799 |
Brugia malayi | nuclear receptor NHR-88 | 0.0124 | 0.1939 | 0.1774 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0124 | 0.1939 | 0.3799 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0264 | 0.5103 | 0.5003 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.0218 | 0.4065 | 0.505 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0053 | 0.031 | 0.0121 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0048 | 0.02 | 0.0392 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.012 | 0.1844 | 0.8342 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 47 % | Percentage inhibition of compound against morphine at 10 e-7 M in guinea pig ileum tissue | ChEMBL. | 2754695 |
Inhibition (functional) | = 79.3 % | Ability to display a naloxone-reversible inhibition of electrically induced contractions in GPI in the presence of 1.0 microM bestatin at concentration 10 e-6 M | ChEMBL. | 2754695 |
Ke (functional) | = 1.4 nM | Inhibitory activity in guinea pig ileum tissue in the absence and presence of 10 nM naloxone | ChEMBL. | 2754695 |
Relative potency (functional) | = 10 | Ability to display a naloxone-reversible inhibition of electrically induced contractions in GPI by Morphine at 0.1 microM | ChEMBL. | 2754695 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.