Detailed information for compound 711451

Basic information

Technical information
  • TDR Targets ID: 711451
  • Name: 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N -(6-ethoxy-1,3-benzothiazol-2-yl)acetamide
  • MW: 367.47 | Formula: C13H13N5O2S3
  • H donors: 2 H acceptors: 4 LogP: 2.89 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc2c(c1)sc(n2)NC(=O)CSc1nnc(s1)N
  • InChi: 1S/C13H13N5O2S3/c1-2-20-7-3-4-8-9(5-7)22-12(15-8)16-10(19)6-21-13-18-17-11(14)23-13/h3-5H,2,6H2,1H3,(H2,14,17)(H,15,16,19)
  • InChiKey: XJBGWVNQVNPSFS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide
  • 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)ethanamide
  • Oprea1_408783
  • ZINC02732194
  • STK220127
  • AN-919/41439902

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0017 0.008 0.0355
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.013 0.0546
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0783 0.5306
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0512 0.6071
Toxoplasma gondii microneme protein, putative 0.0033 0.0281 0.0672
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0033 0.0647
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0054 0.0549 0.6617
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.013 0.1292
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0783 1
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0014 0.0033 0.0096
Brugia malayi PAN domain containing protein 0.0033 0.0281 0.1907
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0783 1
Onchocerca volvulus 0.0033 0.0281 0.3351
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.013 0.1292
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0783 0.5306
Brugia malayi AMP-binding enzyme family protein 0.0021 0.013 0.0881
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.013 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0093 0.0447
Onchocerca volvulus 0.0033 0.0281 0.3351
Schistosoma mansoni hypothetical protein 0.0014 0.0033 0.0647
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0033 0.0647
Brugia malayi Fibulin-1 precursor 0.0013 0.0029 0.0193
Brugia malayi AMP-binding enzyme family protein 0.0021 0.013 0.0881
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0783 1
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.013 0.0881
Loa Loa (eye worm) hypothetical protein 0.0021 0.013 0.0701
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0783 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.013 0.1292
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0549 0.6884
Brugia malayi AMP-binding enzyme family protein 0.0021 0.013 0.0881
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.013 0.1069
Echinococcus granulosus transmembrane protease serine 3 0.0014 0.0033 0.0096
Onchocerca volvulus 0.0033 0.0281 0.3351
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.013 0.0546
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0013 0.0029 0.0193
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.013 0.1292
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.013 0.0701
Loa Loa (eye worm) hypothetical protein 0.0033 0.0281 0.1747
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.013 0.1292
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.013 0.0879
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.013 0.1292
Echinococcus multilocularis enteropeptidase 0.0014 0.0033 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.013 0.1292
Echinococcus multilocularis glycoprotein Antigen 5 0.0014 0.0033 0.0005
Loa Loa (eye worm) hypothetical protein 0.0073 0.0783 0.5214
Echinococcus granulosus tissue type plasminogen activator 0.0051 0.0512 1
Toxoplasma gondii PAN domain-containing protein 0.0309 0.3792 1
Brugia malayi Trypsin family protein 0.0014 0.0033 0.0225
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.013 0.5
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0127 0.1475 1
Brugia malayi Trypsin family protein 0.0014 0.0033 0.0225
Schistosoma mansoni hypothetical protein 0.0051 0.0512 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0783 0.5214
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0014 0.0033 0.0225
Schistosoma mansoni egf-like domain protein 0.0013 0.0029 0.0557
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0051 0.0512 0.9212
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Brugia malayi Trypsin family protein 0.0014 0.0033 0.0225
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.013 0.0546
Onchocerca volvulus 0.0014 0.0033 0.0061
Loa Loa (eye worm) PAN domain-containing protein 0.0033 0.0281 0.1747
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.013 0.1292
Onchocerca volvulus 0.0014 0.0033 0.0061
Echinococcus granulosus Mastin 0.0014 0.0033 0.0096
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0033 0.0647
Echinococcus multilocularis Mastin 0.0014 0.0033 0.0005
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.013 0.5
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Plasmodium falciparum acyl-CoA synthetase 0.0054 0.0549 1
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.013 0.1292
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0783 1
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.013 0.0546
Toxoplasma gondii PAN domain-containing protein 0.0033 0.0281 0.0672
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.013 0.1292
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0512 1
Brugia malayi PAN domain containing protein 0.0033 0.0281 0.1907
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.013 0.0546
Brugia malayi PAN domain containing protein 0.0033 0.0281 0.1907
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0512 0.6071
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0073 0.0783 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0783 1
Schistosoma mansoni phospholipase C beta 0.0017 0.008 0.1559
Toxoplasma gondii PAN/Apple domain-containing protein 0.0033 0.0281 0.0672
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0512 0.6071
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Plasmodium vivax acyl-CoA synthetase, putative 0.0054 0.0549 1
Onchocerca volvulus 0.0021 0.013 0.1345
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0018 0.0093 0.0065
Onchocerca volvulus 0.0033 0.0281 0.3351
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0783 1
Loa Loa (eye worm) PAN domain-containing protein 0.0033 0.0281 0.1747
Loa Loa (eye worm) hypothetical protein 0.0033 0.0281 0.1747
Loa Loa (eye worm) hypothetical protein 0.0033 0.0281 0.1747
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0783 0.5306
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.013 0.0546
Loa Loa (eye worm) hypothetical protein 0.0051 0.0512 0.3343
Onchocerca volvulus 0.0021 0.013 0.1345
Leishmania major phospholipase c-like protein 0.0018 0.0093 0.0189
Loa Loa (eye worm) PAN domain-containing protein 0.0033 0.0281 0.1747
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.013 0.0546
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0073 0.0783 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0033 0.0647
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0014 0.0033 0.0005
Loa Loa (eye worm) hypothetical protein 0.0033 0.0281 0.1747
Brugia malayi Calcium binding EGF domain containing protein 0.0013 0.0029 0.0193
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0033 0.0647
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.013 0.0546
Toxoplasma gondii PAN domain-containing protein 0.0033 0.0281 0.0672
Onchocerca volvulus 0.0033 0.0281 0.3351
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0018 0.0093 0.0447
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.013 0.027
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0013 0.0029 0.0557
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.013 0.027
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0073 0.0783 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0032
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0033 0.0647
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.013 0.0879
Loa Loa (eye worm) Plcb4 protein 0.0017 0.008 0.0355
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.013 0.0879
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.013 0.1292
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.013 0.0881
Toxoplasma gondii microneme protein MIC17C 0.0033 0.0281 0.0672
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.013 0.0879
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0018 0.0093 0.0172
Onchocerca volvulus 0.0033 0.0281 0.3351
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.013 0.0714
Loa Loa (eye worm) hypothetical protein 0.0033 0.0281 0.1747
Schistosoma mansoni hypothetical protein 0.0014 0.0033 0.0647
Loa Loa (eye worm) hypothetical protein 0.0021 0.013 0.0701
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.013 0.0102
Onchocerca volvulus 0.0014 0.0033 0.0061
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.013 0.0714
Brugia malayi AMP-binding enzyme family protein 0.0021 0.013 0.0881
Onchocerca volvulus 0.0014 0.0033 0.0061
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0783 1
Onchocerca volvulus 0.0014 0.0033 0.0061
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.013 0.0701
Brugia malayi Protein kinase domain containing protein 0.0051 0.0512 0.3472
Toxoplasma gondii hypothetical protein 0.0033 0.0281 0.0672
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0033 0.0005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0783 1
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.013 0.1069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0032
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0032
Toxoplasma gondii kringle domain-containing protein 0.0051 0.0512 0.1285
Toxoplasma gondii microneme protein MIC4 0.0033 0.0281 0.0672
Onchocerca volvulus 0.0051 0.0512 0.6412
Toxoplasma gondii microneme protein MIC17B 0.0033 0.0281 0.0672
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0783 1
Toxoplasma gondii PAN domain-containing protein 0.0033 0.0281 0.0672
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.013 0.1292
Toxoplasma gondii subtilisin SUB12 0.0033 0.0281 0.0672
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.013 0.1292
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0512 0.6071
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0017 0.008 0.0541
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0032
Toxoplasma gondii hypothetical protein 0.0033 0.0281 0.0672
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.013 0.2538
Onchocerca volvulus 0.0018 0.0093 0.0857
Brugia malayi hypothetical protein 0.0014 0.0033 0.0225
Loa Loa (eye worm) hypothetical protein 0.0018 0.0093 0.0447
Loa Loa (eye worm) hypothetical protein 0.0073 0.0783 0.5214
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.013 0.1292
Mycobacterium ulcerans hypothetical protein 0.0073 0.0783 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0549 0.3599
Leishmania major hypothetical protein, conserved 0.0051 0.0512 0.615
Onchocerca volvulus 0.0033 0.0281 0.3351
Loa Loa (eye worm) hypothetical protein 0.0033 0.0281 0.1747
Onchocerca volvulus 0.0033 0.0281 0.3351
Brugia malayi PAN domain containing protein 0.0033 0.0281 0.1907
Loa Loa (eye worm) hypothetical protein 0.0033 0.0281 0.1747
Loa Loa (eye worm) hypothetical protein 0.0054 0.0549 0.3599
Loa Loa (eye worm) PAN domain-containing protein 0.0033 0.0281 0.1747
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.013 0.0546
Echinococcus multilocularis transmembrane protease serine 3 0.0014 0.0033 0.0005
Brugia malayi Trypsin family protein 0.0014 0.0033 0.0225
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0014 0.0033 0.0647
Brugia malayi Kringle domain containing protein 0.0051 0.0512 0.3472
Onchocerca volvulus 0.0073 0.0783 1
Onchocerca volvulus 0.0021 0.013 0.1345
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0033 0.0281 0.0672
Toxoplasma gondii PAN domain-containing protein 0.0309 0.3792 1
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.013 0.1292
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.013 0.2098
Brugia malayi PAN domain containing protein 0.0033 0.0281 0.1907
Toxoplasma gondii PAN domain-containing protein 0.0033 0.0281 0.0672
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Entamoeba histolytica acyl-coA synthetase, putative 0.0073 0.0783 1
Onchocerca volvulus 0.0033 0.0281 0.3351
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0018 0.0093 0.0631
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0018 0.0093 0.1336
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.013 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.013 0.0546
Brugia malayi PAN domain containing protein 0.0033 0.0281 0.1907
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.013 0.0546
Brugia malayi PAN domain containing protein 0.0033 0.0281 0.1907
Onchocerca volvulus 0.0018 0.0093 0.0857
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.013 0.1292
Toxoplasma gondii microneme protein MIC17A 0.0033 0.0281 0.0672
Echinococcus granulosus glycoprotein Antigen 5 0.0014 0.0033 0.0096
Onchocerca volvulus 0.0033 0.0281 0.3351
Brugia malayi PAN domain containing protein 0.0033 0.0281 0.1907
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0783 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0549 0.3599
Plasmodium falciparum cysteine repeat modular protein 1 0.0051 0.0512 0.9212
Echinococcus multilocularis tissue type plasminogen activator 0.0051 0.0512 0.0485
Onchocerca volvulus 0.0021 0.013 0.1345
Loa Loa (eye worm) hypothetical protein 0.0054 0.0549 0.3599
Loa Loa (eye worm) TK/ROR protein kinase 0.0051 0.0512 0.3343
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0032
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0033 0.0647
Brugia malayi Variant SH3 domain containing protein 0.0127 0.1475 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0033 0.0647
Loa Loa (eye worm) hypothetical protein 0.0054 0.0549 0.3599
Onchocerca volvulus 0.0033 0.0281 0.3351
Toxoplasma gondii propionate-CoA ligase 0.0021 0.013 0.027
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0783 1
Brugia malayi PAN domain containing protein 0.0033 0.0281 0.1907
Echinococcus granulosus enteropeptidase 0.0014 0.0033 0.0096
Loa Loa (eye worm) oxidoreductase 0.0021 0.013 0.0701
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.013 0.0714
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0054 0.0549 0.5
Loa Loa (eye worm) trypsin family protein 0.0014 0.0033 0.0032
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0073 0.0783 1
Loa Loa (eye worm) PAN domain-containing protein 0.0033 0.0281 0.1747
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0017 0.008 0.0541
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.013 0.1292
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0014 0.0033 0.0096
Brugia malayi Trypsin-like protease protein 5 0.0014 0.0033 0.0225
Onchocerca volvulus 0.0014 0.0033 0.0061
Brugia malayi PAN domain containing protein 0.0033 0.0281 0.1907

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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