Detailed information for compound 722234

Basic information

Technical information
  • TDR Targets ID: 722234
  • Name: 3-(5-chloro-2-methoxyphenyl)-1-(thiophen-2-yl methyl)urea
  • MW: 296.773 | Formula: C13H13ClN2O2S
  • H donors: 2 H acceptors: 1 LogP: 2.74 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1NC(=O)NCc1cccs1)Cl
  • InChi: 1S/C13H13ClN2O2S/c1-18-12-5-4-9(14)7-11(12)16-13(17)15-8-10-3-2-6-19-10/h2-7H,8H2,1H3,(H2,15,16,17)
  • InChiKey: FBOBCUZXTZGRQW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(5-chloro-2-methoxy-phenyl)-1-(2-thienylmethyl)urea
  • 3-(5-chloro-2-methoxyphenyl)-1-(2-thienylmethyl)urea
  • 3-(5-chloro-2-methoxy-phenyl)-1-(thiophen-2-ylmethyl)urea
  • ZINC00609112
  • IVK/1639352

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0075 0.0082
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0266 0.0291
Mycobacterium tuberculosis Conserved hypothetical protein 0.0005 0.0032 0.0886
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0745 0.1124
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0266 0.0291
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0266 0.0291
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0339 0.4554
Onchocerca volvulus 0.0014 0.0248 0.4407
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0339 0.9307
Brugia malayi Cam kinase protein 1 0.0031 0.0642 0.2802
Treponema pallidum threonyl-tRNA synthetase 0.0006 0.0048 0.141
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0745 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0563 0.246
Brugia malayi neuropeptide F receptor 0.0015 0.0266 0.1162
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0248 0.1084
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0266 0.0291
Onchocerca volvulus 0.0014 0.0248 0.4407
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Brugia malayi Sugar transporter family protein 0.0014 0.0248 0.1084
Entamoeba histolytica protein kinase, putative 0.0031 0.0642 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0061 0.0267
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Schistosoma mansoni neuropeptide receptor 0.0015 0.0266 0.0291
Schistosoma mansoni hypothetical protein 0.0395 0.9162 1
Trypanosoma brucei glucose transporter 2A 0.0031 0.0651 0.8738
Echinococcus granulosus solute carrier family 22 0.0014 0.0248 0.0271
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0006 0.0048 0.0262
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0445 0.5966
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus multilocularis sex peptide receptor 0.0015 0.0266 0.0291
Echinococcus granulosus g protein coupled receptor 0.0015 0.0266 0.0291
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0651 0.8738
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0006 0.0048 0.0072
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0266 0.0291
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0642 0.8612
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0248 0.0271
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0266 0.0291
Schistosoma mansoni glycyl-tRNA synthetase 0.0006 0.0048 0.0052
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0266 0.0291
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0651 0.2843
Schistosoma mansoni amine GPCR 0.0015 0.0266 0.0291
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0248 0.3332
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0248 0.0271
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0011 0.0166 0.3243
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0365 0.5587
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0248 0.3332
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0006 0.0048 0.0209
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0339 0.0339
Loa Loa (eye worm) sugar transporter 0.0102 0.2291 1
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0651 0.2843
Plasmodium falciparum protein kinase 7 0.0287 0.6628 0.6628
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0266 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0061 0.0267
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0266 0.0291
Schistosoma mansoni opsin-like receptor 0.0015 0.0266 0.0291
Schistosoma mansoni amine GPCR 0.0015 0.0266 0.0291
Schistosoma mansoni neuropeptide receptor 0.0015 0.0266 0.0291
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0266 0.0291
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0445 0.0485
Onchocerca volvulus 0.0015 0.0266 0.4724
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0266 0.0291
Echinococcus granulosus neuropeptide s receptor 0.0015 0.0266 0.0291
Onchocerca volvulus 0.0015 0.0266 0.4724
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0248 0.5239
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0642 0.0642
Plasmodium vivax threonine--tRNA ligase, putative 0.0006 0.0048 0.0048
Brugia malayi Sugar transporter family protein 0.0014 0.0248 0.1084
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0445 0.6932
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0266 0.1162
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0266 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0061 0.0267
Schistosoma mansoni amine GPCR 0.0015 0.0266 0.0291
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0266 0.0291
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0365 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0032 0.0141
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0642 0.0701
Brugia malayi hypothetical protein 0.0015 0.0266 0.1162
Onchocerca volvulus 0.0014 0.0248 0.4407
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0006 0.0048 0.0746
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0266 0.1162
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0266 0.0291
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.0266 0.0291
Leishmania major hypothetical protein, conserved 0.0005 0.0032 0.0433
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0339 0.1482
Chlamydia trachomatis proline--tRNA ligase 0.0011 0.0166 0.2978
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0642 0.0642
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0006 0.0048 0.0642
Entamoeba histolytica protein kinase, putative 0.0031 0.0642 1
Onchocerca volvulus 0.0015 0.0266 0.4724
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0248 0.1084
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0266 0.0291
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0006 0.0048 0.0209
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2291 0.25
Schistosoma mansoni amine GPCR 0.0015 0.0266 0.0291
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0266 0.0291
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Schistosoma mansoni hypothetical protein 0.0015 0.0266 0.0291
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0642 0.0701
Onchocerca volvulus 0.0014 0.0248 0.4407
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0379 0.1656
Onchocerca volvulus 0.0014 0.0248 0.4407
Onchocerca volvulus 0.0014 0.0248 0.4407
Schistosoma mansoni histamine h1 receptor 0.0015 0.0266 0.0291
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0339 0.037
Onchocerca volvulus 0.0015 0.0266 0.4724
Schistosoma mansoni myosin xvIII 0.0015 0.0266 0.0291
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Brugia malayi major facilitator superfamily protein 0.0014 0.0248 0.1084
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0445 1
Toxoplasma gondii glycyl-tRNA synthetase 0.0006 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Trypanosoma cruzi hypothetical protein, conserved 0.0005 0.0032 0.0433
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Schistosoma mansoni biogenic amine receptor 0.0015 0.0266 0.0291
Brugia malayi hypothetical protein 0.0014 0.0248 0.1084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Schistosoma mansoni neuropeptide receptor 0.0015 0.0266 0.0291
Onchocerca volvulus 0.0015 0.0266 0.4724
Giardia lamblia Threonyl-tRNA synthetase 0.0006 0.0048 0.0763
Toxoplasma gondii facilitative glucose transporter GT1 0.0102 0.2291 0.3456
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Plasmodium vivax CDK-related protein kinase 6, putative 0.0431 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0266 0.0291
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0266 0.1162
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0266 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.2291 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0266 0.0291
Onchocerca volvulus 0.0015 0.0266 0.4724
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0266 0.0291
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0061 0.0267
Echinococcus granulosus allatostatin A receptor 0.0015 0.0266 0.0291
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0266 0.0291
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0651 0.8738
Brugia malayi RE15519p 0.0015 0.0266 0.1162
Schistosoma mansoni sugar transporter 0.0014 0.0248 0.0271
Echinococcus granulosus serotonin receptor 0.0015 0.0266 0.0291
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.003 0.0627 0.0684
Leishmania major hypothetical protein, conserved 0.0005 0.0032 0.0433
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Leishmania major protein kinase, putative 0.0031 0.0642 0.8612
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0642 0.0642
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0266 0.0291
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0061 0.0267
Schistosoma mansoni glucose transporter 0.0014 0.0248 0.0271
Loa Loa (eye worm) hypothetical protein 0.003 0.0627 0.2738
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Plasmodium falciparum hexose transporter 0.0102 0.2291 0.2291
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0266 0.1162
Schistosoma mansoni glucose transport protein 0.0102 0.2291 0.25
Onchocerca volvulus 0.0028 0.0563 1
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.003 0.0627 0.2738
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0005 0.0032 0.0433
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0266 0.0291
Brugia malayi hypothetical protein 0.0015 0.0266 0.1162
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0445 0.0485
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2291 0.25
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0266 0.0291
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0642 0.0701
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0642 0.0969
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0266 0.0291
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0102 0.2291 0.25
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0642 0.0642
Brugia malayi neuropeptide F receptor 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0339 0.5412
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0115 0.0126
Brugia malayi ORL1-like opioid receptor 0.0015 0.0266 0.1162
Echinococcus multilocularis somatostatin receptor 0.0015 0.0266 0.0291
Echinococcus multilocularis cpg binding protein 0.0029 0.06 0.0655
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0061 0.0267
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0266 0.1162
Schistosoma mansoni opsin-like receptor 0.0015 0.0266 0.0291
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0266 0.0291
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0014 0.0248 0.6876
Echinococcus granulosus sex peptide receptor 0.0015 0.0266 0.0291
Trypanosoma brucei glucose transporter 1E 0.0031 0.0651 0.8738
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0642 0.0642
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0164 0.3754 0.5664
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2291 0.25
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Brugia malayi Dopamine receptor 0.0015 0.0266 0.1162
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0248 0.1084
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0266 0.1162
Echinococcus granulosus neuropeptide receptor 0.0015 0.0266 0.0291
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2291 0.25
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0207 0.0903
Schistosoma mansoni hypothetical protein 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Onchocerca volvulus 0.0014 0.0248 0.4407
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Onchocerca volvulus 0.0015 0.0266 0.4724
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0266 0.0291
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0248 0.0375
Brugia malayi F/Y-rich N-terminus family protein 0.0008 0.0112 0.0491
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0745 0.0745
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0266 0.0291
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.003 0.0627 0.2738
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0266 0.0291
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0339 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.0266 0.4724
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0339 0.1482
Echinococcus multilocularis solute carrier family 22 0.0014 0.0248 0.0271
Echinococcus granulosus g protein coupled receptor 0.0015 0.0266 0.0291
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0266 0.0291
Leishmania major glucose transporter, lmgt2 0.0031 0.0651 0.8738
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0115 0.0126
Brugia malayi hypothetical protein 0.0015 0.0266 0.1162
Brugia malayi follicle stimulating hormone receptor 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0031 0.0642 0.2802
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0061 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0061 0.0267
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus granulosus somatostatin receptor 0.0015 0.0266 0.0291
Onchocerca volvulus 0.0014 0.0248 0.4407
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0075 0.0082
Schistosoma mansoni sugar transporter 0.0014 0.0248 0.0271
Brugia malayi larval opioid receptor 0.0015 0.0266 0.1162
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0266 0.0291
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0445 0.0445
Schistosoma mansoni cpg binding protein 0.0028 0.0563 0.0615
Echinococcus multilocularis solute carrier family 22 0.0014 0.0248 0.0271
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0445 0.1941
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.003 0.0627 1
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.003 0.0627 0.2738
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0445 0.0485
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus granulosus orexin receptor type 2 0.0015 0.0266 0.0291
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0061 0.0267
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0651 0.2843
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0266 0.0291
Giardia lamblia Glycyl-tRNA synthetase 0.0006 0.0048 0.0763
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0266 0.0291
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0339 0.1482
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0445 0.0671
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0248 0.3332
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0248 0.0271
Trypanosoma brucei glucose transporter, putative 0.0031 0.0651 0.8738
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0266 0.0291
Echinococcus granulosus cpg binding protein 0.0029 0.06 0.0655
Trypanosoma brucei glucose transporter, putative 0.0031 0.0651 0.8738
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0266 0.0291
Brugia malayi glycyl-tRNA synthetase 0.0006 0.0048 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0061 0.0267
Giardia lamblia Hexose transporter 0.0014 0.0248 0.3959
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.0266 0.0291
Brugia malayi Serotonin receptor 0.0015 0.0266 0.1162
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0266 0.0291
Echinococcus multilocularis solute carrier family 22 0.0014 0.0248 0.0271
Brugia malayi G-protein coupled receptor 0.0015 0.0266 0.1162
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0248 0.5239
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0445 0.5966
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0075 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0248 0.1084
Onchocerca volvulus 0.0015 0.0266 0.4724
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Brugia malayi CXXC zinc finger family protein 0.0028 0.0563 0.246
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0266 0.1162
Loa Loa (eye worm) sugar transporter 0.0014 0.0248 0.1084
Leishmania major threonyl-tRNA synthetase, putative 0.0006 0.0048 0.0642
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0266 0.0291
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0642 0.0701
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0006 0.0048 0.0209
Brugia malayi hypothetical protein 0.0015 0.0266 0.1162
Leishmania major glucose transporter, lmgt3 0.0031 0.0651 0.8738
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0266 0.0291
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus granulosus hypothetical protein 0.0015 0.0266 0.0291
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0745 1
Echinococcus multilocularis solute carrier family 22 0.0014 0.0248 0.0271
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0445 0.0485
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0266 0.0291
Giardia lamblia Sugar-proton symporter 0.0014 0.0248 0.3959
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0445 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0266 0.0291
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0266 0.0291
Brugia malayi Dopamine receptor protein 1 0.0015 0.0266 0.1162
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0248 0.1084
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0032 0.0141
Onchocerca volvulus 0.0014 0.0248 0.4407
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0006 0.0048 0.0209
Trypanosoma cruzi hypothetical protein, conserved 0.0005 0.0032 0.0433
Onchocerca volvulus 0.0015 0.0266 0.4724
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Plasmodium vivax hexose transporter 0.0102 0.2291 0.2291
Schistosoma mansoni ap endonuclease 0.0018 0.0339 0.037
Brugia malayi G protein-coupled receptor 0.0015 0.0266 0.1162
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0642 0.0701
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0642 0.0642
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0075 0.0082
Echinococcus multilocularis glycyl tRNA synthetase 0.0006 0.0048 0.0052
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0266 0.1162
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0248 0.0271
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0005 0.0032 0.0049
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0005 0.0032 0.0433
Trypanosoma brucei sugar transporter, putative 0.0014 0.0248 0.3332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0266 0.0291
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0266 0.0291
Echinococcus granulosus dnaJ subfamily B 0.0395 0.9162 1
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0248 0.6809
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0115 0.0502
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0745 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus multilocularis serotonin receptor 0.0015 0.0266 0.0291
Brugia malayi hypothetical protein 0.0014 0.0248 0.1084
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0266 0.1162
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0048 0.0642
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2291 0.25
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0339 0.1482
Brugia malayi Melatonin receptor type 1A 0.0015 0.0266 0.1162
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0248 0.1084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0642 0.2802
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.1291 0.141
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2291 0.25
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0365 1
Onchocerca volvulus 0.0015 0.0266 0.4724
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0266 0.0291
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0339 0.5287
Toxoplasma gondii sugar transporter ST3 0.0014 0.0248 0.0375
Loa Loa (eye worm) hypothetical protein 0.0025 0.0493 0.2154
Brugia malayi sulfakinin receptor protein 0.0015 0.0266 0.1162
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0005 0.0032 0.0433
Plasmodium falciparum threonine--tRNA ligase 0.0006 0.0048 0.0048
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0266 0.1162
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0445 1
Brugia malayi hypothetical protein 0.0015 0.0266 0.1162
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0248 0.6809
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0651 0.8738
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.003 0.0627 0.0684
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus granulosus fmrfamide receptor 0.0015 0.0266 0.0291
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0248 0.5239
Schistosoma mansoni biogenic amine receptor 0.0015 0.0266 0.0291
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0266 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0032 0.0141
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0266 0.0291
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0597 0.0651
Schistosoma mansoni biogenic amine receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0266 0.1162
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0248 0.1084
Schistosoma mansoni protein kinase 0.0031 0.0642 0.0701
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0642 0.0701
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0023 0.0445 0.1941
Echinococcus multilocularis General substrate transporter 0.0087 0.1956 0.2135
Leishmania major glucose transporter, lmgt1 0.0031 0.0651 0.8738
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0266 0.0291
Brugia malayi Sugar transporter family protein 0.0102 0.2291 1
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0006 0.0048 0.1312
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0266 0.1162
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0248 0.1084
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0651 0.2843
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0266 0.0291
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0006 0.0048 0.0746
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0651 0.8738
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0627 0.0684
Plasmodium vivax glycine--tRNA ligase, putative 0.0006 0.0048 0.0048
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0006 0.0048 0.0377
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0248 0.1084
Echinococcus granulosus solute carrier family 22 0.0014 0.0248 0.0271
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0266 0.1162
Schistosoma mansoni neuropeptide receptor 0.0015 0.0266 0.0291
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0266 0.0291
Trypanosoma brucei glucose transporter, putative 0.0031 0.0651 0.8738
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0075 0.0082
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0266 0.0291
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0642 0.0642
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0061 0.0267
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0651 0.8738
Schistosoma mansoni amine GPCR 0.0015 0.0266 0.0291
Brugia malayi Serotonin receptor 0.0015 0.0266 0.1162
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0339 0.4554
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Toxoplasma gondii protein kinase, putative 0.0287 0.6628 1
Onchocerca volvulus 0.0015 0.0266 0.4724
Mycobacterium ulcerans sugar transporter 0.0014 0.0248 0.5239
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0266 0.0291
Onchocerca volvulus 0.0015 0.0266 0.4724
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0006 0.0048 0.0052
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0339 0.0339
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0266 0.0291
Brugia malayi AKH receptor 0.0015 0.0266 0.1162
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Loa Loa (eye worm) hypothetical protein 0.003 0.0627 0.2738
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0248 0.3332
Leishmania major hypothetical protein, conserved 0.0014 0.0248 0.3332
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0266 0.0291
Echinococcus granulosus Threonyl tRNA synthetase C 0.0006 0.0048 0.0052
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0266 0.0291
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.0266 0.4724
Schistosoma mansoni hypothetical protein 0.0102 0.2291 0.25
Schistosoma mansoni hypothetical protein 0.0015 0.0266 0.0291
Brugia malayi G-protein coupled receptor 0.0015 0.0266 0.1162
Trypanosoma brucei glucose transporter, putative 0.0031 0.0651 0.8738
Onchocerca volvulus 0.0014 0.0248 0.4407
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0266 0.0291
Echinococcus granulosus General substrate transporter 0.0087 0.1956 0.2135
Onchocerca volvulus 0.0015 0.0266 0.4724
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus granulosus solute carrier family 22 0.0014 0.0248 0.0271
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0745 1
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0266 0.0291
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0266 0.0291
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0445 0.5966
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0248 0.0248
Brugia malayi hypothetical protein 0.0015 0.0266 0.1162
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0642 0.0969
Schistosoma mansoni glucose transport protein 0.0102 0.2291 0.25
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0266 0.0291
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0061 0.0267
Trypanosoma cruzi hexose transporter 0.0031 0.0651 0.8738
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0651 0.2843
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0266 0.0291
Echinococcus granulosus glycyl tRNA synthetase 0.0006 0.0048 0.0052
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0651 0.2843
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0642 0.0642
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.1144 0.1726
Schistosoma mansoni cpg binding protein 0.0029 0.06 0.0655
Brugia malayi major facilitator superfamily protein 0.0014 0.0248 0.1084
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0048 0.0642
Onchocerca volvulus 0.0014 0.0248 0.4407
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0061 0.0267
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0266 0.0291
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0266 0.0291
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0164 0.3754 0.3754
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0642 0.0701
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0266 0.0291
Trichomonas vaginalis helicase, putative 0.0006 0.0061 0.0267
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0061 0.0267
Brugia malayi hypothetical protein 0.0015 0.0266 0.1162
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0339 0.4554
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0642 0.0701
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0597 0.0651
Schistosoma mansoni opsin-like receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Brugia malayi hypothetical protein 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0248 0.1084
Brugia malayi putative neuropeptide receptor 0.0015 0.0266 0.1162
Onchocerca volvulus 0.0014 0.0248 0.4407
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0445 0.709
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Schistosoma mansoni protein kinase 0.0031 0.0642 0.0701
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0248 0.3332
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0339 0.7448
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0642 0.2802
Treponema pallidum prolyl-tRNA synthetase 0.0011 0.0166 0.4891
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0266 0.0291
Onchocerca volvulus 0.0014 0.0248 0.4407
Onchocerca volvulus 0.0015 0.0266 0.4724
Echinococcus granulosus solute carrier family 22 0.0014 0.0248 0.0271
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0642 0.0969
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0248 0.1084
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0339 0.037
Echinococcus multilocularis serotonin receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0266 0.0291
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0745 0.0745
Onchocerca volvulus 0.0015 0.0266 0.4724
Brugia malayi GnHR receptor homolog 0.0015 0.0266 0.1162
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0651 0.8738
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0642 0.2802
Toxoplasma gondii sugar transporter ST2 0.0014 0.0248 0.0375
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.9162 1
Plasmodium falciparum mitogen-activated protein kinase 2 0.0164 0.3754 0.3754
Trypanosoma brucei glucose transporter, putative 0.0031 0.0651 0.8738
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0061 0.0267
Giardia lamblia Prolyl-tRNA synthetase 0.003 0.0627 1
Onchocerca volvulus 0.0014 0.0248 0.4407
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0642 0.0642
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0248 0.1084
Schistosoma mansoni sugar transporter 0.0014 0.0248 0.0271
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0445 0.1941
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Onchocerca volvulus 0.0014 0.0248 0.4407
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0642 0.2802
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2291 0.25
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0006 0.0048 0.0642
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0339 0.4554
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0266 0.0291
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0266 0.0291
Brugia malayi hypothetical protein 0.0015 0.0266 0.1162
Schistosoma mansoni ap endonuclease 0.0018 0.0339 0.037
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0642 0.0701
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0317 0.4254
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0015 0.0266 0.1162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0061 0.0267
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0266 0.0291
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0266 0.0291
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0627 0.0684
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0061 0.0267
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0266 0.0291
Brugia malayi hypothetical protein 0.0014 0.0248 0.1084
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0006 0.0048 0.0377
Echinococcus granulosus g protein coupled receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0006 0.0048 0.0209
Schistosoma mansoni hypothetical protein 0.0015 0.0266 0.0291
Onchocerca volvulus 0.0015 0.0266 0.4724
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0004 0.0007 0.0008
Brugia malayi hypothetical protein 0.0015 0.0266 0.1162
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0266 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0248 0.1084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.003 0.0627 0.977
Onchocerca volvulus 0.0014 0.0248 0.4407
Toxoplasma gondii sugar transporter ST1 0.0014 0.0248 0.0375
Onchocerca volvulus 0.0015 0.0266 0.4724
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0651 0.2843
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0339 1
Toxoplasma gondii exonuclease III APE 0.0018 0.0339 0.0512
Echinococcus granulosus neuropeptide receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Schistosoma mansoni adenoreceptor 0.0015 0.0266 0.0291
Schistosoma mansoni glucose transport protein 0.0102 0.2291 0.25
Trypanosoma brucei glucose transporter, putative 0.0031 0.0651 0.8738
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0266 0.0291
Trypanosoma brucei glucose transporter, putative 0.0031 0.0651 0.8738
Schistosoma mansoni sugar transporter 0.0014 0.0248 0.0271
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Onchocerca volvulus Putative transporter 0.0014 0.0248 0.4407
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0266 0.0291
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0266 0.0291
Loa Loa (eye worm) hypothetical protein 0.0014 0.0248 0.1084
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0248 0.0271
Trypanosoma brucei glucose transporter, putative 0.0031 0.0651 0.8738
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0248 0.1084
Entamoeba histolytica hypothetical protein 0.0023 0.0445 0.6927
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0266 0.0291
Plasmodium vivax sugar transporter, putative 0.0014 0.0248 0.0248
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0445 0.0445
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0266 0.1162
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0745 1
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0006 0.0048 0.0209
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0651 0.8738
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0266 0.0291
Brugia malayi Dopamine receptor protein 2 0.0015 0.0266 0.1162
Loa Loa (eye worm) hypothetical protein 0.0015 0.0266 0.1162
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0266 0.0291
Schistosoma mansoni cpg binding protein 0.0029 0.06 0.0655
Schistosoma mansoni protein kinase 0.0031 0.0642 0.0701

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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