Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0461 | 0.6069 | 1 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0187 | 0.2283 | 0.3761 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0187 | 0.2283 | 0.3761 |
Entamoeba histolytica | phenylalanyl-tRNA synthetase alpha subunit, putative | 0.0174 | 0.209 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0217 | 0.0898 |
Echinococcus multilocularis | phenylalanyl tRNA synthetase | 0.0116 | 0.129 | 0.2126 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase subunit alpha | 0.0174 | 0.209 | 0.5665 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase subunit alpha | 0.0066 | 0.06 | 0.1625 |
Onchocerca volvulus | 0.0048 | 0.0347 | 0.5 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0185 | 0.0304 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.032 | 0.0867 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0438 | 0.0722 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0108 | 0.1189 | 0.1959 |
Leishmania major | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0174 | 0.209 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0289 | 0.369 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0108 | 0.1189 | 0.3222 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0108 | 0.1189 | 0.5483 |
Treponema pallidum | phenylalanyl-tRNA synthetase subunit alpha | 0.0174 | 0.209 | 1 |
Plasmodium falciparum | phenylalanine--tRNA ligase | 0.0084 | 0.0853 | 0.3802 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0438 | 0.0722 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0066 | 0.06 | 0.2532 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0347 | 0.1528 |
Wolbachia endosymbiont of Brugia malayi | phenylalanyl-tRNA synthetase subunit alpha | 0.0745 | 1 | 0.5 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0438 | 0.1188 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0347 | 0.0941 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0108 | 0.1189 | 0.5184 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.209 | 1 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0048 | 0.0347 | 0.0688 |
Mycobacterium tuberculosis | Probable phenylalanyl-tRNA synthetase, alpha chain PheS | 0.0745 | 1 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0108 | 0.1189 | 0.3222 |
Toxoplasma gondii | phenylalanyl-tRNA synthetase alpha chain A, putative | 0.0174 | 0.209 | 1 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0438 | 0.1174 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0438 | 0.1971 |
Trypanosoma cruzi | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0174 | 0.209 | 1 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase mitochondrial | 0.0116 | 0.129 | 0.3497 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0513 | 0.0845 |
Plasmodium vivax | phenylalanine--tRNA ligase, putative | 0.0066 | 0.06 | 0.2532 |
Echinococcus granulosus | phenylalanyl tRNA synthetase alpha chain B | 0.0174 | 0.209 | 0.3444 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0108 | 0.1189 | 0.5483 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0251 | 0.0174 |
Plasmodium falciparum | phenylalanine--tRNA ligase | 0.0116 | 0.129 | 0.5992 |
Echinococcus granulosus | neuropeptide s receptor | 0.0461 | 0.6069 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.0562 | 0.1523 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0108 | 0.1189 | 0.5184 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0347 | 0.1528 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.0724 | 0.3359 |
Loa Loa (eye worm) | phenylalanyl-tRNA synthetase | 0.0116 | 0.129 | 0.5726 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0174 | 0.209 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0347 | 0.0688 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0108 | 0.1189 | 0.5483 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0438 | 0.0722 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0108 | 0.1189 | 0.5483 |
Brugia malayi | phosphofructokinase | 0.0108 | 0.1189 | 0.5618 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0438 | 0.1174 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0185 | 0.0304 |
Echinococcus granulosus | phenylalanyl tRNA synthetase | 0.0116 | 0.129 | 0.2126 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0048 | 0.0347 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0665 | 0.2385 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.032 | 0.0867 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0108 | 0.1189 | 0.1959 |
Plasmodium vivax | phenylalanine--tRNA ligase alpha subunit, putative | 0.0174 | 0.209 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0461 | 0.6069 | 1 |
Trypanosoma brucei | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0174 | 0.209 | 1 |
Giardia lamblia | Phenylalanyl-tRNA synthetase alpha chain | 0.0174 | 0.209 | 1 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0048 | 0.0347 | 0.0572 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0048 | 0.0347 | 0.0941 |
Plasmodium falciparum | phenylalanine--tRNA ligase alpha subunit | 0.0174 | 0.209 | 1 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0066 | 0.06 | 0.2532 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.032 | 0.0543 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0461 | 0.6069 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0108 | 0.1189 | 0.5618 |
Echinococcus multilocularis | phenylalanyl tRNA synthetase alpha chain B | 0.0174 | 0.209 | 0.3444 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.032 | 0.1397 |
Plasmodium vivax | phenylalanine--tRNA ligase, putative | 0.0116 | 0.129 | 0.5992 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0108 | 0.1189 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.032 | 0.0527 |
Toxoplasma gondii | Ferredoxin-fold anticodon binding domain-containing protein | 0.0116 | 0.129 | 0.5992 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.032 | 0.0527 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0108 | 0.1189 | 0.5483 |
Brugia malayi | phenylalanyl (f) trna synthetase protein 1 | 0.0174 | 0.209 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0347 | 0.0941 |
Brugia malayi | 6-phosphofructokinase | 0.0108 | 0.1189 | 0.5618 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.032 | 0.0527 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0048 | 0.0347 | 0.0572 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0048 | 0.0347 | 0.0572 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0108 | 0.1189 | 0.5483 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0108 | 0.1189 | 0.5483 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0513 | 0.0845 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0277 | 0.0315 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.032 | 0.0527 |
Brugia malayi | phenylalanyl-tRNA synthetase, mitochondrial precursor, putative | 0.0116 | 0.129 | 0.6112 |
Loa Loa (eye worm) | phosphofructokinase | 0.0108 | 0.1189 | 0.5184 |
Mycobacterium ulcerans | phenylalanyl-tRNA synthetase subunit alpha | 0.0745 | 1 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0108 | 0.1189 | 0.5483 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0438 | 0.0722 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0048 | 0.0347 | 0.0572 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.032 | 0.0867 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.