Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0435 | 1 | 1 |
Giardia lamblia | Cathepsin L-like protease | 0.008 | 0 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0435 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0224 | 0.4054 | 0.4054 |
Giardia lamblia | Cathepsin B precursor | 0.008 | 0 | 0.5 |
Brugia malayi | 4-hydroxyphenylpyruvate dioxygenase family protein | 0.0354 | 0.7723 | 0.7723 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0435 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0435 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.1791 | 0.1791 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0224 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0435 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.008 | 0 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0435 | 1 | 1 |
Onchocerca volvulus | 0.0435 | 1 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0291 | 0.5946 | 0.5946 |
Leishmania major | cathepsin L-like protease | 0.0435 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.008 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0224 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0435 | 1 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.008 | 0 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0291 | 0.5946 | 0.5946 |
Echinococcus multilocularis | cathepsin L | 0.0224 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0435 | 1 | 1 |
Schistosoma mansoni | cathepsin s | 0.0144 | 0.1791 | 0.1791 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.1791 | 0.1791 |
Onchocerca volvulus | Cathepsin L homolog | 0.0435 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0224 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | cysteine protease | 0.0435 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0435 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.008 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Onchocerca volvulus | 0.0291 | 0.5946 | 0.5946 | |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.1791 | 0.1791 |
Plasmodium vivax | vivapain-1 | 0.0224 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | fibroinase | 0.0435 | 1 | 1 |
Echinococcus granulosus | cathepsin L | 0.0224 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0291 | 0.5946 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.008 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0291 | 0.5946 | 0.5946 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0435 | 1 | 1 |
Loa Loa (eye worm) | 4-hydroxyphenylpyruvate dioxygenase | 0.0354 | 0.7723 | 0.7723 |
Onchocerca volvulus | 0.0435 | 1 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0224 | 0.4054 | 0.4054 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0435 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0435 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0291 | 0.5946 | 0.5946 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.008 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0224 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | ctsf protein | 0.0435 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.5946 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0435 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.008 | 0 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0435 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0435 | 1 | 1 |
Giardia lamblia | Cysteine protease | 0.008 | 0 | 0.5 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.008 | 0 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0435 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0435 | 1 | 1 |
Plasmodium vivax | vivapain-3 | 0.0224 | 0.4054 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Onchocerca volvulus | 0.0435 | 1 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0224 | 0.4054 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0224 | 0.4054 | 0.4054 |
Plasmodium vivax | unspecified product | 0.0224 | 0.4054 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0224 | 0.4054 | 0.4054 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0435 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0435 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0144 | 0.1791 | 0.1791 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0144 | 0.1791 | 0.1791 |
Brugia malayi | Cathepsin L-like precursor | 0.0144 | 0.1791 | 0.1791 |
Echinococcus multilocularis | cysteine protease | 0.0435 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.008 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.008 | 0 | 0.5 |
Onchocerca volvulus | 0.0435 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Echinococcus granulosus | cysteine protease | 0.0224 | 0.4054 | 0.4054 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0291 | 0.5946 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0224 | 0.4054 | 0.4054 |
Onchocerca volvulus | 0.0435 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.5946 | 0.5946 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0144 | 0.1791 | 0.1791 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0224 | 0.4054 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Brugia malayi | cathepsin L-like precursor | 0.0291 | 0.5946 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Giardia lamblia | Encystation-specific protease | 0.008 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.008 | 0 | 0.5 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.008 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0224 | 0.4054 | 0.4054 |
Giardia lamblia | Hypothetical protein | 0.008 | 0 | 0.5 |
Echinococcus granulosus | cathepsin l1 | 0.0291 | 0.5946 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0435 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0224 | 0.4054 | 0.4054 |
Onchocerca volvulus | Cathepsin F homolog | 0.0435 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.008 | 0 | 0.5 |
Onchocerca volvulus | 0.0435 | 1 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0435 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0291 | 0.5946 | 0.5946 |
Giardia lamblia | Cathepsin L precursor | 0.008 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 1 | 1 |
Onchocerca volvulus | Putative protein | 0.0354 | 0.7723 | 0.7723 |
Brugia malayi | Cathepsin L-like precursor | 0.0435 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0224 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0224 | 0.4054 | 0.4054 |
Giardia lamblia | Cysteine protease | 0.008 | 0 | 0.5 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0144 | 0.1791 | 0.1791 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0224 | 0.4054 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0224 | 0.4054 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Onchocerca volvulus | Cathepsin L homolog | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0224 | 0.4054 | 0.4054 |
Plasmodium vivax | unspecified product | 0.0144 | 0.1791 | 0.1791 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0435 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0435 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.5946 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.008 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.008 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0291 | 0.5946 | 0.5946 |
Trypanosoma cruzi | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0224 | 0.4054 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.008 | 0 | 0.5 |
Onchocerca volvulus | 0.0435 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0224 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0224 | 0.4054 | 0.4054 |
Giardia lamblia | Cathepsin B precursor | 0.008 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 1 | 1 |
Giardia lamblia | Cysteine protease | 0.008 | 0 | 0.5 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0435 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0435 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0435 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0435 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0435 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Giardia lamblia | Cysteine protease | 0.008 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0435 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0224 | 0.4054 | 0.4054 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0144 | 0.1791 | 0.1791 |
Leishmania major | cysteine peptidase A (CPA) | 0.0435 | 1 | 1 |
Giardia lamblia | Cathepsin L-like protease | 0.008 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0435 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.